-
1
-
-
23944518960
-
A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay
-
DOI 10.1016/j.ijpharm.2005.05.034, PII S0378517305003418
-
Balimane PV and Chong S (2005) A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay. Int J Pharm 301:80-88. (Pubitemid 41206593)
-
(2005)
International Journal of Pharmaceutics
, vol.301
, Issue.1-2
, pp. 80-88
-
-
Balimane, P.V.1
Chong, S.2
-
2
-
-
2942682950
-
Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery
-
DOI 10.1016/j.ejpb.2004.02.014, PII S0939641104000554
-
Balimane PV, Patel K, Marino A, and Chong S (2004) Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery. Eur J Pharm Biopharm 58:99-105. (Pubitemid 38781010)
-
(2004)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.58
, Issue.1
, pp. 99-105
-
-
Balimane, P.V.1
Patel, K.2
Marino, A.3
Chong, S.4
-
3
-
-
4143142207
-
Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: Potential role for breast cancer resistance protein in clinical drug-drug interactions
-
DOI 10.1158/0008-5472.CAN-03-4062
-
Breedveld P, Zelcer N, Pluim D, Sönmezer O, Tibben MM, Beijnen JH, Schinkel AH, van Tellingen O, Borst P, and Schellens JH (2004) Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. Cancer Res 64:5804-5811. (Pubitemid 39095580)
-
(2004)
Cancer Research
, vol.64
, Issue.16
, pp. 5804-5811
-
-
Breedveld, P.1
Zelcer, N.2
Pluim, D.3
Sonmezer, O.4
Tibben, M.M.5
Beijnen, J.H.6
Schinkel, A.H.7
Van Tellingen, O.8
Borst, P.9
Schellens, J.H.M.10
-
4
-
-
84859926767
-
PhIP transport in ABCG2 stably transfected MDCKII cells
-
American Association of Pharmaceutical Scientists Meeting; 2006 Nov 1; San Antonio, TX Abstract W5320
-
Empey PE, Leggas M, and McNamara PJ (2006) PhIP transport in ABCG2 stably transfected MDCKII cells. American Association of Pharmaceutical Scientists Meeting; 2006 Nov 1; San Antonio, TX. AAPS PharmSci 8(S2), Abstract W5320.
-
(2006)
AAPS PharmSci
, vol.8
, Issue.S2
-
-
Empey, P.E.1
Leggas, M.2
McNamara, P.J.3
-
5
-
-
0034987671
-
Active transport of nitrofurantoin into human milk
-
Gerk PM, Kuhn RJ, Desai NS, and McNamara PJ (2001) Active transport of nitrofurantoin into human milk. Pharmacotherapy 21:669-675. (Pubitemid 32506482)
-
(2001)
Pharmacotherapy
, vol.21
, Issue.6
, pp. 669-675
-
-
Gerk, P.M.1
Kuhn, R.J.2
Desai, N.S.3
McNamara, P.J.4
-
6
-
-
77649216536
-
Membrane transporters in drug development
-
Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, et al. (2010) Membrane transporters in drug development. Nat Rev Drug Discov 9:215-236.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
Chu, X.6
Dahlin, A.7
Evers, R.8
Fischer, V.9
Hillgren, K.M.10
-
7
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
-
DOI 10.1038/nm1186
-
Jonker JW, Merino G, Musters S, van Herwaarden AE, Bolscher E, Wagenaar E, Mesman E, Dale TC, and Schinkel AH (2005) The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nat Med 11:127-129. (Pubitemid 40321346)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
Van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
Mesman, E.7
Dale, T.C.8
Schinkel, A.H.9
-
8
-
-
33846116128
-
Kinetic considerations for the quantitative assessment of efflux activity and inhibition: Implications for understanding and predicting the effects of efflux inhibition
-
DOI 10.1007/s11095-006-9135-x
-
Kalvass JC and Pollack GM (2007) Kinetic considerations for the quantitative assessment of efflux activity and inhibition: implications for understanding and predicting the effects of efflux inhibition. Pharm Res 24:265-276. (Pubitemid 46072186)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.2
, pp. 265-276
-
-
Kalvass, J.C.1
Pollack, G.M.2
-
10
-
-
33645108568
-
Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion
-
Merino G, Alvarez AI, Pulido MM, Molina AJ, Schinkel AH, and Prieto JG (2006) Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion. Drug Metab Dispos 34:690-695.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 690-695
-
-
Merino, G.1
Alvarez, A.I.2
Pulido, M.M.3
Molina, A.J.4
Schinkel, A.H.5
Prieto, J.G.6
-
11
-
-
17844369140
-
Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2)
-
DOI 10.1124/dmd.104.003319
-
Merino G, Jonker JW, Wagenaar E, Pulido MM, Molina AJ, Alvarez AI, and Schinkel AH (2005) Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2). Drug Metab Dispos 33:614-618. (Pubitemid 40593873)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.5
, pp. 614-618
-
-
Merino, G.1
Jonker, J.W.2
Wagenaar, E.3
Pulido, M.M.4
Molina, A.J.5
Alvarez, A.I.6
Schinkel, A.H.7
-
14
-
-
34250695989
-
Abcg2/Bcrp1 mediates the polarized transport of antiretroviral nucleosides abacavir and zidovudine
-
DOI 10.1124/dmd.106.014274
-
Pan G, Giri N, and Elmquist WF (2007) Abcg2/Bcrp1 mediates the polarized transport of antiretroviral nucleosides abacavir and zidovudine. Drug Metab Dispos 35:1165-1173. (Pubitemid 46956438)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.7
, pp. 1165-1173
-
-
Pan, G.1
Giri, N.2
Elmquist, W.F.3
-
16
-
-
37549046023
-
Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: A theoretical study
-
Sun H and Pang KS (2008) Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: a theoretical study. Drug Metab Dispos 36:102-123.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 102-123
-
-
Sun, H.1
Pang, K.S.2
-
17
-
-
0035103370
-
Stereoselective pharmacokinetics of pantoprazole, a proton pump inhibitor, in extensive and poor metabolizers of S-mephenytoin
-
DOI 10.1067/mcp.2001.113723
-
Tanaka M, Ohkubo T, Otani K, Suzuki A, Kaneko S, Sugawara K, Ryokawa Y, and Ishizaki T (2001) Stereoselective pharmacokinetics of pantoprazole, a proton pump inhibitor, in extensive and poor metabolizers of S-mephenytoin. Clin Pharmacol Ther 69:108-113. (Pubitemid 32225410)
-
(2001)
Clinical Pharmacology and Therapeutics
, vol.69
, Issue.3
, pp. 108-113
-
-
Tanaka, M.1
Ohkubo, T.2
Otani, K.3
Suzuki, A.4
Kaneko, S.5
Sugawara, K.6
Ryokawa, Y.7
Ishizaki, T.8
-
18
-
-
33846903263
-
2) into milk
-
DOI 10.1128/MCB.01621-06
-
van Herwaarden AE, Wagenaar E, Merino G, Jonker JW, Rosing H, Beijnen JH, and Schinkel AH (2007) Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk. Mol Cell Biol 27:1247-1253. (Pubitemid 46239808)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.4
, pp. 1247-1253
-
-
Van Herwaarden, A.E.1
Wagenaar, E.2
Merino, G.3
Jonker, J.W.4
Rosing, H.5
Beijnen, J.H.6
Schinkel, A.H.7
-
19
-
-
59049084011
-
Physiological and pharmacological roles of ABCG2 (BCRP): Recent findings in Abcg2 knockout mice
-
Vlaming ML, Lagas JS, and Schinkel AH (2009) Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice. Adv Drug Deliv Rev 61:14-25.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 14-25
-
-
Vlaming, M.L.1
Lagas, J.S.2
Schinkel, A.H.3
-
20
-
-
57349095219
-
N-(4-[2-(1,2,3,4- Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl) -9,10-dihydro-5-methoxy-9-oxo-4- acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin transfer into milk
-
Wang L, Leggas M, Goswami M, Empey PE, and McNamara PJ (2008) N-(4-[2-(1,2,3,4- Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10- dihydro-5-methoxy-9-oxo-4- acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin transfer into milk. Drug Metab Dispos 36:2591-2596.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 2591-2596
-
-
Wang, L.1
Leggas, M.2
Goswami, M.3
Empey, P.E.4
McNamara, P.J.5
-
21
-
-
84859921105
-
Stereoselective Interaction of Pantoprazole with ABCG2. I. Drug accumulation in rat milk
-
Wang L and McNamara PJ (2012) Stereoselective Interaction of Pantoprazole with ABCG2. I. Drug accumulation in rat milk. Drug Metab Dispos 40:1018-1023.
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 1018-1023
-
-
Wang, L.1
McNamara, P.J.2
-
22
-
-
25144473985
-
Pharmacokinetic differences between pantoprazole enantiomers in rats
-
DOI 10.1007/s11095-005-6807-x
-
Xie Z, Zhang Y, Xu H, and Zhong D (2005) Pharmacokinetic differences between pantoprazole enantiomers in rats. Pharm Res 22:1678-1684. (Pubitemid 41355907)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.10
, pp. 1678-1684
-
-
Xie, Z.1
Zhang, Y.2
Xu, H.3
Zhong, D.4
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