Evolution of acoustically vaporized microdroplets in gas embolotherapy

Journal of Biomechanical Engineering

Volumn 134, Issue 3, 2012, Pages

  Qamar, Adnan ^a,b   Wong, Zheng Z ^a   Fowlkes, J Brian ^c   Bull, Joseph L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMBIENT CONDITIONS; BUBBLE RADIUS; COMPUTATIONAL APPROACH; COMPUTATIONAL MODELING; DODECAFLUOROPENTANE; DROPLET SIZES; EVOLUTION PROCESS; FLUID PRESSURES; GAS BUBBLE; GAS EMBOLOTHERAPY; MICRO DROPLETS; MICROTUBE; PRESSURE PULSE; SHEAR STRESS AMPLITUDE; SPHERICAL BUBBLES; TRANSIENT BUBBLES; TUBE DIAMETERS; TUBE WALLS; ULTRA HIGH SPEED; VISCOUS DISSIPATION;

BUBBLES (IN FLUIDS); DYNAMICS; SHEAR STRESS; STRESS CONCENTRATION; TUBES (COMPONENTS); VAPORIZATION; VAPORS;

DROPS;

PERFLUOROPENTANE; MICROSPHERE;

ACOUSTIC DROPLET VAPORIZATION; AMPLITUDE MODULATION; ARTICLE; ARTIFICIAL EMBOLISM; FLOW KINETICS; GAS EMBOLOTHERAPY; MATHEMATICAL MODEL; MICROBUBBLE; MOLECULAR DYNAMICS; PARTICLE SIZE; PRESSURE; SHEAR STRESS; SURFACE TENSION; TUBE; VAPORIZATION; VISCOSITY; ACOUSTICS; CHEMISTRY; GAS; MECHANICAL STRESS; METHODOLOGY; THEORETICAL MODEL; VOLATILIZATION;

ACOUSTICS; EMBOLIZATION, THERAPEUTIC; GASES; MICROCHEMISTRY; MICROSPHERES; MODELS, THEORETICAL; PRESSURE; STRESS, MECHANICAL; VOLATILIZATION;

EID: 84859884462     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4005980     Document Type: Article

References (39)

1. Golzarian, J., Sun, S., and Sharafuddin, M. J., 2006, Vascular Embolotherapy: A Comprehensive Approach, Springer-Verlag, Berlin, Vol. 1.
2. Boehm, T., Folkman, J., Browder, T., and O'Reilly, M. S., 1997, Antiangiogenic Therapy of Experimental Cancer Does Not Induce Acquired Drug Resistance., Nature (London), 390, pp. 404-407. (Pubitemid 28027321)
3. Di Segni, R., Young, A. T., Zhong, Q., and Castaneda-Zuniga, W. R., 1997, Embolotherapy: Agents, Equipment, and Techniques, in Interventional Radiology, W. R. Castaneda-Zuniga, ed., Williams and Wilkins, Baltimore.
4. Bull, J. L., 2007, The Application of Microbubbles for Targeted Drug Delivery., Expert Opin. Drug Delivery, 4, pp. 475-493. (Pubitemid 47527330)
5. Bull, J. L., 2005, Cardiovascular Bubble Dynamics., Crit. Rev. Biomed. Eng., 33, pp. 299-346. (Pubitemid 40840001)
6. Apfel, R., 1998, Activatable Infusable Dispersions Containing Drops of a Superheated Liquid for Methods of Therapy and Diagnosis., US Patent No. 5,840,276.
7. Quay, S.C., 1996, Phase Shift Colloids as Ultrasound Contrast Agents., US Patent No. 5,558,853.
8. Kripfgans, O. D., Fowlkes, J. B., Woydt, M., Eldevik, O. P., and Carson, P. L., 2002, in vivo Droplet Vaporization for Occlusion Therapy and Phase Aberration Correction., IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 49, pp. 726-738. (Pubitemid 34773069)
9. Haworth, K. J., Fowlkes, J. B., Carson, P. L., and Kripfgans, O.D., 2008, Towards Aberration Correction of Transcranial Ultrasound Using Acoustic Droplet Vaporization., Ultrasound Med. Biol., 34, pp. 435-445. (Pubitemid 351625440)
10. Fabiilli, M. L., Haworth, K. J., Sebastian, I. E., Kripfgans, O. D., Carson, P. L., and Fowlkes, J. B., 2010, Delivery of Chlorambucil using an Acoustically-Triggered Perfluoropentane Emulsion., Ultrasound Med. Biol., 36, pp. 1364-1375.
11. Fabiilli, M. L., Lee, J. A., Kripfgans, O. D., Carson, P. L., and Fowlkes, J. B., 2010, Delivery of Water-Soluble Drugs using Acoustically Triggered Perfluorocarbon Double Emulsions., Pharm. Res., 27, pp. 2753-2765.
12. Miller, D. L., Kripfgans, O. D., Fowlkes, J. B., and Carson, P. L., 2000, Cavitation Nucleation Agents for Non-Thermal Ultrasound Therapy., J. Acoust. Soc. Am., 107, pp. 3480-3486. (Pubitemid 30397041)
13. Zhang, P., and Porter, T., 2010, An In Vitro Study of a Phase-Shift Nanoemulsion: A Potential Nucleation Agent for Bubble-Enhanced HIFU Tumor Ablation., Ultrasound Med. Biol., 36, pp. 1856-1866.
14. Kripfgans, O. D., Fowlkes, J. B., Miller, D. L., Eldevik O. P., and Carson, P. L., 2000, Acoustic Droplet Vaporization for Therapeutic and Diagnostic Applications., Ultrasound Med. Biol., 26, pp. 1177-1189.
15. Kripfgans, O. D., Fabiilli, M. L., Carson, P. L., and Fowlkes, J. B., 2004, On the Acoustic Vaporization of Micrometer-Sized Droplet., J. Acoust. Soc. Am., 116, pp. 272-281.
16. Lo, A. H., Kripfgans, O. D., Carson, P. L., Rothman, E. D., and Fowlkes, J. B., 2007, Acoustic Droplet Vaporization Threshold: Effects of Pulse Duration and Contrast Agent., IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 54, pp. 933-946.
17. Fabiilli, M. L., Haworth, K. J., Fakhri, N. H., Kripfgans, O. D., Carson, P. L., and Fowlkes, J., B., 2009, The Role of Inertial Cavitation in Acoustic Droplet Vaporization., IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 56, pp. 1006-1017.
18. Giesecke, T., and Hynynen, K., 2003, Ultrasound-Mediated Cavitation Thresholds of Liquid Perfluorocarbon Droplets In Vitro., UltrasoundMed. Biol., 29, pp. 1359-1365. (Pubitemid 37211336)
19. Ye, T., and Bull, J. L., 2004, Direct Numerical Simulations of Micro-Bubble Expansion in Gas Embolotherapy., J. Biomech. Eng., 126, pp. 745-759. (Pubitemid 40293724)
20. Ye, T., and Bull, J. L., 2006, Microbubble Expansion in a Flexible Tube., J. Biomech. Eng., 128, pp. 554-563. (Pubitemid 44187315)
21. Wong, Z. Z., 2009, Gas Embolotherapy: Bubble Evolution in Acoustic Droplet Vaporization and Design of a Benchtop Microvascular Model., Ph.D. thesis, University of Michigan, Ann Arbor.
22. Wong, Z. Z., Kripfgans, O. D., Qamar, A., Fowlkes, J. B., and Bull, J. L, 2011, Bubble Evolution in Acoustic Droplet Vaporization at Physiological Temperature via Ultra-High Speed Imaging., Soft Matter, 7, pp. 4009-4016.
23. Qamar, A., Wong, Z. Z., Fowlkes, J. B., and Bull, J. L., 2010, Dynamics of Acoustic Droplet Vaporization in Gas Embolotherapy., Appl. Phys. Lett. 96 (14), 143702.
24. Shepherd, J. E., and Sturtevant, B., 1982, Rapid Evaporation at the Superheat Limit., J. Fluid Mech., 121, pp. 379-402.
25. Avedisian, C. T, 1986, Bubble growth in superheated liquid droplets, Encyclopedia of Fluid Mechanics, Vol 3: Gas Liquid Flow, N. P. Cheremisnoff, ed., Gulf Publishing, Houston Texas.
26. McCann, H., Clarke, L. J., and Masters, A. P., 1989, An Experimetal Study of Vapour Growth at Superheated Limit Temperature., Int. J. Heat Mass Transfer, 32, pp. 1077-1093. (Pubitemid 21659984)
27. Chitavins, S. M., 1987, Explosive Vaporization of Small Droplets by a High Energy Laser Beam., J. Appl. Phys., 62, pp. 4387-4394.
28. Frost, D. L., 1989, Initiation of Explosive of a Droplet with Shock Wave., Exp. Fluids, 8, pp. 121-128. (Pubitemid 20667777)
29. Curra, F. P., Mourad, P. D., Khokhlova, V. A., Cleveland, R. O., and Crum, L. A., 2000, Numerical Simulations of Heating Patterns and Tissue Temperature Response due to High-Intensity focused Ultrasound., IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 47, pp. 1077-1089.
30. Billard, B. E., Hynynen, K., and Roemer, R. B., 1990, Effects of Physical Parameters on High Temperature Ultrasound Hyperthermia., Ultrasound Med. Biol., 16, pp. 409-420. (Pubitemid 20241984)
31. Carey, V. P., 1992, Liquid-Vapor Phase Change Phenomena, Hemisphere, Washington.
32. Demirdzic I., and Peric, M., 1988, Space Conservation Law in Finite Volume Calculations of Fluid Flow., Int. J. Numer. Methods Fluids, 8, pp. 1037-1050. (Pubitemid 18661739)
33. Peri, M., and Ferziger, J. H., 2002, Computational Fluid Dynamics, 3rd ed., Springer-Verlag, New York.
34. Demirdzic, I., and Muzaferija, S., 1995, Numerical Method for Coupled Fluid Flow, Heat Transfer and Stress Analysis using Unstructured Moving Meshes with Cells of Arbitrary Topology., Comput. Methods Appl. Mech. Eng., 125, pp. 235-255.
35. Patankar, S. V., and Spalding, D. B., 1972, A Calculation Procedure for Heat, Mass and Momentum Transfer in Three-Dimensional Parabolic Flows., Int. J. Heat Mass Transfer, 15, pp. 1787-1806.
36. Demirdzic, I., Lilek, Z., and Peri, M., 1993, A Collocated Finite Volume Method for Predicting Flows at All Speeds., Int. J. Numer. Methods Fluids, 16, pp. 1029-1050.
37. Frost, D. L., 1988, Dynamics of Explosive Boiling of a Droplet., Phys. Fluids, 31, pp. 2554-2561.
38. Dewey, C. F., Bussolari, S. R., Gimbrone, M. A., and Davies, P. F., 1981, The Dynamic Response of Vascular Endothelial Cell to Fluid Shear Stress., J. Biomed. Eng., 103, pp. 177-185.
39. Fung, Y. C., 1997, Biomechanics: Circulation, Springer, New York.