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Volumn 27, Issue 5, 2012, Pages 651-655

Prerequisites to launch neuroprotective trials in Parkinson's disease: An industry perspective

Author keywords

Clinical trials; Neuroprotection; Parkinson's disease; Pre motor

Indexed keywords

ACHIEVEMENT; ARTICLE; CLINICAL TRIAL (TOPIC); CONSENSUS; DISEASE CONTROL; DISEASE COURSE; FEASIBILITY STUDY; HEALTH CARE INDUSTRY; HUMAN; NEUROPROTECTION; PARKINSON DISEASE; PATIENT ADVOCACY; PERSONALIZED MEDICINE; PRIORITY JOURNAL; PROGRAM DEVELOPMENT; PROPHYLAXIS; PUBLIC-PRIVATE PARTNERSHIP; SAMPLE SIZE; STANDARDIZATION;

EID: 84859874196     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25017     Document Type: Article
Times cited : (18)

References (22)
  • 1
    • 34147164484 scopus 로고    scopus 로고
    • Neuroprotection in Parkinson's disease: an elusive goal
    • Biglan KM, Ravina B. Neuroprotection in Parkinson's disease: an elusive goal. Semin Neurol 2007; 27: 106-112.
    • (2007) Semin Neurol , vol.27 , pp. 106-112
    • Biglan, K.M.1    Ravina, B.2
  • 2
    • 0025651148 scopus 로고
    • Striatonigral degeneration. A clinicopathological study
    • Fearnley JM, Lees AJ. Striatonigral degeneration. A clinicopathological study. Brain 1990; 113: 1823-1842.
    • (1990) Brain , vol.113 , pp. 1823-1842
    • Fearnley, J.M.1    Lees, A.J.2
  • 3
    • 2942647959 scopus 로고    scopus 로고
    • Central nervous system atrophy and clinical status in multiple sclerosis
    • Zivadinov R, Bakshi R. Central nervous system atrophy and clinical status in multiple sclerosis. J Neuroimaging 2004; 14: 27S-35S.
    • (2004) J Neuroimaging , vol.14
    • Zivadinov, R.1    Bakshi, R.2
  • 4
    • 70349456475 scopus 로고    scopus 로고
    • A double-blind, delayed-start trial of rasagiline in Parkinson's disease
    • Olanow CW, Rascol O, Hauser R, et al. A double-blind, delayed-start trial of rasagiline in Parkinson's disease. N Engl J Med 2009; 361: 1268-1278.
    • (2009) N Engl J Med , vol.361 , pp. 1268-1278
    • Olanow, C.W.1    Rascol, O.2    Hauser, R.3
  • 5
    • 0024343466 scopus 로고
    • The effect of deprenyl (selegiline) on the natural history of Parkinson's disease
    • Tetrud JW, Langston JW. The effect of deprenyl (selegiline) on the natural history of Parkinson's disease. Science 1989; 245: 519-522.
    • (1989) Science , vol.245 , pp. 519-522
    • Tetrud, J.W.1    Langston, J.W.2
  • 6
    • 0029790469 scopus 로고    scopus 로고
    • Observations and suggestions on antidementia drug development
    • Leber P. Observations and suggestions on antidementia drug development. Alzheimer Dis Assoc Disord 1996; 10: 31-35.
    • (1996) Alzheimer Dis Assoc Disord , vol.10 , pp. 31-35
    • Leber, P.1
  • 7
    • 0030865454 scopus 로고    scopus 로고
    • Slowing the progression of Alzheimer disease: methodologic issues
    • Leber P. Slowing the progression of Alzheimer disease: methodologic issues. Alzheimer Dis Assoc Disord 1997; 11: 10-21.
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , pp. 10-21
    • Leber, P.1
  • 8
    • 61449173973 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics
    • Olanow CW, Hauser RA, Jankovic J, et al. A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics. Mov Disord 2008; 23: 2194-2201.
    • (2008) Mov Disord , vol.23 , pp. 2194-2201
    • Olanow, C.W.1    Hauser, R.A.2    Jankovic, J.3
  • 9
    • 73349136256 scopus 로고    scopus 로고
    • Endpoints and analyses to discern disease-modifying drug effects in early Parkinson's disease
    • Bhattaram VA, Siddiqui O, Kapcala LP, Gobburu JVS. Endpoints and analyses to discern disease-modifying drug effects in early Parkinson's disease. AAPS J 2009; 11: 456-464.
    • (2009) AAPS J , vol.11 , pp. 456-464
    • Bhattaram, V.A.1    Siddiqui, O.2    Kapcala, L.P.3    Gobburu, J.V.S.4
  • 10
    • 0347093537 scopus 로고    scopus 로고
    • The evaluation of disease modifying therapies in Alzheimer's disease: a regulatory viewpoint
    • Mani RB. The evaluation of disease modifying therapies in Alzheimer's disease: a regulatory viewpoint. Stat Med 2004; 23: 305-314.
    • (2004) Stat Med , vol.23 , pp. 305-314
    • Mani, R.B.1
  • 11
    • 70349467696 scopus 로고    scopus 로고
    • The delayed-start study design
    • D'Agostino RBSr. The delayed-start study design. N Engl J Med 2009; 361: 1304-1306.
    • (2009) N Engl J Med , vol.361 , pp. 1304-1306
    • D'Agostino Sr, R.B.1
  • 12
    • 40449088027 scopus 로고    scopus 로고
    • Biomarkers for the early detection of Parkinson's and Alzheimer's disease
    • Berg D. Biomarkers for the early detection of Parkinson's and Alzheimer's disease. Neurodegener Dis 2008; 5: 133-136.
    • (2008) Neurodegener Dis , vol.5 , pp. 133-136
    • Berg, D.1
  • 13
    • 61949280270 scopus 로고    scopus 로고
    • "Disease-modification" trials in Parkinson disease: target populations, endpoints and study design
    • Rascol O. "Disease-modification" trials in Parkinson disease: target populations, endpoints and study design. Neurology 2009; 72: S51-S58.
    • (2009) Neurology , vol.72
    • Rascol, O.1
  • 15
    • 84859846991 scopus 로고    scopus 로고
    • Defining at-risk populations for Parkinson's disease: lessons from ongoing studies
    • Berg D, Marek K, Ross GW, Poewe W. Defining at-risk populations for Parkinson's disease: lessons from ongoing studies. Mov Disord 2012; 27: 656-665.
    • (2012) Mov Disord , vol.27 , pp. 656-665
    • Berg, D.1    Marek, K.2    Ross, G.W.3    Poewe, W.4
  • 16
    • 77956808929 scopus 로고    scopus 로고
    • Defining disease-modifying therapies for PD-a road map for moving forward
    • Olanow CW, Kieburtz K. Defining disease-modifying therapies for PD-a road map for moving forward. Mov Disord 2010; 25: 1774-1779.
    • (2010) Mov Disord , vol.25 , pp. 1774-1779
    • Olanow, C.W.1    Kieburtz, K.2
  • 17
    • 84859874695 scopus 로고    scopus 로고
    • Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's Disease
    • Postuma RB, Aarsland D, Barone P, et al. Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's Disease. Mov Disord 2012; 27: 617-626.
    • (2012) Mov Disord , vol.27 , pp. 617-626
    • Postuma, R.B.1    Aarsland, D.2    Barone, P.3
  • 18
    • 84863115941 scopus 로고    scopus 로고
    • Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab
    • Ostrowitzki S, Deptula D, Thurfjell L, et al. Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab. Arch Neurol 2012; 69: 198-207.
    • (2012) Arch Neurol , vol.69 , pp. 198-207
    • Ostrowitzki, S.1    Deptula, D.2    Thurfjell, L.3
  • 19
    • 77949300796 scopus 로고    scopus 로고
    • 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
    • Rinne JO, Brooks DJ, Rossor MN, et al. 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. Lancet Neurol 2010; 9: 363-372.
    • (2010) Lancet Neurol , vol.9 , pp. 363-372
    • Rinne, J.O.1    Brooks, D.J.2    Rossor, M.N.3
  • 20
    • 84859813166 scopus 로고    scopus 로고
    • Pre-motor Parkinson's disease: concepts and definitions
    • Siderowf A, Lang AE. Pre-motor Parkinson's disease: concepts and definitions. Mov Disord 2012; 27: 608-616.
    • (2012) Mov Disord , vol.27 , pp. 608-616
    • Siderowf, A.1    Lang, A.E.2
  • 21
    • 84859856337 scopus 로고    scopus 로고
    • Motor signs in the prodromal phase of Parkinson's disease
    • Maetzler W, Hausdorff JM. Motor signs in the prodromal phase of Parkinson's disease. Mov Disord 2012; 27: 627-633.
    • (2012) Mov Disord , vol.27 , pp. 627-633
    • Maetzler, W.1    Hausdorff, J.M.2
  • 22
    • 84859877206 scopus 로고    scopus 로고
    • Neuroimaging: current role in detecting pre-motor Parkinson's disease
    • Godau J, Hussl A, Lolekha P, Stoessl AJ, Seppi K. Neuroimaging: current role in detecting pre-motor Parkinson's disease. Mov Disord 2012; 27: 634-643.
    • (2012) Mov Disord , vol.27 , pp. 634-643
    • Godau, J.1    Hussl, A.2    Lolekha, P.3    Stoessl, A.J.4    Seppi, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.