Evaluation of dysplasia through detailed cytomorphology in 3156 patients from the Düsseldorf Registry on myelodysplastic syndromes

Leukemia Research

Volumn 36, Issue 6, 2012, Pages 727-734

  Germing, Ulrich ^a   Strupp, Corinna ^a   Giagounidis, Aristoteles ^b   Haas, Rainer ^a   Gattermann, Norbert ^a   Starke, Carsten ^a   Aul, Carlo ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b ST JOHANNES HOSPITAL   (Germany)

Author keywords

Cytomorphology; Dysplastic features; Myelodysplastic syndromes

Indexed keywords

5Q- SYNDROME; ARTICLE; CELL STRUCTURE; CHRONIC MYELOMONOCYTIC LEUKEMIA; CONTROLLED STUDY; DISEASE CLASSIFICATION; ERYTHROPOIESIS; GRANULOPOIESIS; HUMAN; MAJOR CLINICAL STUDY; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; REFRACTORY ANEMIA WITH EXCESS BLASTS; REFRACTORY ANEMIA WITH EXCESS BLASTS IN TRANSFORMATION; REFRACTORY ANEMIA WITH RINGED SIDEROBLASTS; REFRACTORY CYTOPENIA WITH MULTILINEAGE DYSPLASIA; REFRACTORY CYTOPENIA WITH MULTILINEAGE DYSPLASIA AND RINGED SIDEROBLASTS; REFRACTORY CYTOPENIA WITH UNILINEAGE DYSPLASIA; RELIABILITY;

BONE MARROW CELLS; COHORT STUDIES; CYTOLOGICAL TECHNIQUES; ERYTHROPOIESIS; GERMANY; HEMATOPOIESIS; HUMANS; MYELODYSPLASTIC SYNDROMES; NEOPLASM STAGING; PROGNOSIS; REGISTRIES;

EID: 84859860919     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2012.02.014     Document Type: Article

References (25)

1. Bennett J.M., Catovsky D., Daniel M.T., Flandrin G., Galton D.A., Gralnick H.R., et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982, 51:189-199.
2. Bennett J.M. World Health Organization classification of the acute leukemias and myelodysplastic syndrome. Int J Hematol 2000, 72:131-133.
3. Brunning R.D., Orazi A., Germing U., LeBeau M.M., Porwit A., Baumann I., et al. Myelodysplastic syndromes/neoplasms overview. WHO classification of tumours of haematopoietic and lympoid tissues 2008, 88-93. IARC Press, Lyon. E. Jaffe, N.L. Harris, S.H. Swerdlow, J. Vardiman (Eds.).
4. Begemann H., Rastetter J., Heilmeyer L. Atlas der Klinischen Hämatologie 1996, vol. 4. Aufl, Springer.
5. Shibata A., Bennett J.M., Castoldi G.L., Catovsky D., Flandrin G., Jaffe E.S., et al. Recommended methods for cytological procedures in haematology International Committee for Standardization in Haematology (ICSH). Clin Lab Haematol 1985, 7:55-74.
6. Seligman A.M., Hanker J.S., Wasserkrug H., Dmochowski H., Katzoff L. Histochemical demonstration of some oxidized macromolecules with thiocarbohydrazide (TCH) or thiosemicarbazide (TSC) and osmium tetroxide. J Histochem Cytochem 1965, 13:629-639.
7. McManus J.F.A. Stain Tech 1946, 23:99.
8. Löffler H. Cytochemischer Nachweis von unspezifischer Esterase in Ausstrichen. Klin Wschr 1961, 39:1220-1227.
9. Kurijama K., Tomonaga M., Matsuo T., Jinnai I., Ichimaru M. Diagnostic significance of detecting pseudo-Pelger-Huet anomalies and micromegakaryocytes in myelodysplastic syndromes. Br J Haematol 1986, 63:665-669.
10. Van der Weide M., Sizoo W., Krefft J., Langenhuijsen M.M. Myelodysplastic syndromes: analysis of morphologic features related to the FAB classification. Eur J Haematol 1988, 41:58-61.
11. Gattermann N., Aul C., Schneider W. Two types of acquired idiopathic sideroblastic anaemia (AISA). Br J Haematol 1990, 74:45-52.
12. Garand R., Gardais J., Bizet M., Bremond J.L., Accard F., Callat M.P., et al. Heterogeneity of acquired idiopathic sideroblastic anaemia (AISA). Leuk Res 1992, 16:463-468.
13. Balduini C.L., Guarnone R., Pecci A., Centenara E., Ascari E. Multilineage dysplasia without increased blasts identifies a poor prognosis subset of myelodysplastic syndromes. Leukemia 1998, 12:1655-1656.
14. Matsuda A., Jinnai I., Yagasaki F., Kusumoto S., Minamihisamatsu M., Honda S., et al. Refractory anemia with severe dysplasia: clinical significance of morphological features in refractory anemia. Leukemia 1998, 12:482-485.
15. Rosati S., Mick R., Xu F., Stonys E., Le Beau M.M., Larson R., et al. Refractory cytopenia with multilineage dysplasia: further characterization of an 'unclassifiable' myelodysplastic syndrome. Leukemia 1996, 10:20-26.
16. Germing U., Gattermann N., Aivado M., Hildebrandt B., Aul C. Two types of acquired idiopathic sideroblastic anaemia (AISA): a time-tested distinction. Br J Haematol 2000, 108:724-728.
17. Germing U., Gattermann N., Strupp C., Aivado M., Aul C. Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: a retrospective analysis of 1600 patients. Leuk Res 2000, 24:983-992.
18. Germing U., Strupp C., Knipp S., Kuendgen A., Giagounidis A., Hildebrandt B., et al. Chronic myelomonocytic leukemia in the light of the WHO proposals. Haematologica 2007, 92:974-977.
19. Giagounidis A.A., Germing U., Haase S., Hildebrandt B., Schlegelberger B., Schoch C., et al. Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31. Leukemia 2004, 18:113-199.
20. Malcovati L., Germing U., Kuendgen A., DellaPorta M.G., Pascutto C., Invernizzi R., et al. Time dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes. J Clin Oncol 2007, 25:3503-3510.
21. Cervera J., Solé F., Haase D., LuñoE, Such E., Nomdedeu B., et al. Prognostic impact on survival of an unsuccessful conventional cytogenetic study in patients with myelodysplastic syndromes (MDS). Leuk Res 2009, 33(Suppl. 1):75-76.
22. Matsuda A., Germing U., Jinnai I., Iwanaga M., Misumi M., Kuendgen A., et al. Improvement of criteria for refractory cytopenia with multilineage dysplasia according to the WHO classification based on prognostic significance of morphological features in patients with refractory anemia according to the FAB classification. Leukemia 2007, 21:678-686.
23. Marisavljevic D., Rolovic Z., Cemerikic V., Boskovic D., Colovic M. Myelofibrosis in primary myelodysplastic syndromes: clinical and biological significance. Med Oncol 2004, 21:325-331.
24. Tuzuner N., Cox C., Rowe J.M., Watrous D., Bennett J.M. Hypocellular myelodysplastic syndromes (MDS): new proposals. Br J Haematol 1995, 91:612-617.
25. Büsche G., Teoman H., Wilczak W., Ganser A., Hecker H., Wilkens L., et al. Marrow fibrosis predicts early fatal marrow failure in patients with MDS. Leukemia 2008, 22:313-322.