Angiotensin-converting enzyme gene insertion/deletion polymorphism and essential hypertension in the Chinese population: A meta-analysis including 21058 participants

Internal Medicine Journal

Volumn 42, Issue 4, 2012, Pages 439-444

  Li, Y ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme; Chinese; Hypertension; Insertion deletion polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; CHINESE; DNA POLYMORPHISM; EMBASE; ESSENTIAL HYPERTENSION; GENE DELETION; GENE FREQUENCY; GENE INSERTION; HUMAN; MEDLINE; META ANALYSIS; PRIORITY JOURNAL; SYSTEMATIC REVIEW;

ASIAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; INDEL MUTATION; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 84859857881     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2011.02584.x     Document Type: Article

References (13)

1. Newhouse SJ, Wallace C, Dobson R, Mein C, Pembroke J, Farrall M etal. Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Hum Mol Genet 2005; 14: 1805-14.
2. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1343-6.
3. Mondry A, Loh M, Liu P, Zhu AL, Nagel M. Polymorphisms of the insertion / deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data. BMC Nephrol 2005; 6: 1-11.
4. Ji LD, Zhang LN, Shen P, Wang P, Zhang YM, Xing WH etal. Association of angiotensinogen gene M235T and angiotensin-converting enzyme gene I/D polymorphisms with essential hypertension in Han Chinese population: a meta-analysis. J Hypertens 2010; 28: 419-28.
5. Cochran WG. The effectiveness of adjustment by subclassification in removing bias in observational studies. Biometrics 1968; 24: 295-313.
6. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-48.
7. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.
8. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. Br Med J 1997; 315: 629-34.
9. Harbord RM, Egger M, Sterne1 JAC. A modified test for small study effects in meta-analyses of controlled trials with binary endpoints. Stat Med 2006; 25: 3443-57.
10. Barley J, Blackwood A, Carter ND, Crews DE, Cruickshank JK, Jeffery S etal. Angiotensin converting enzyme insertion/deletion polymorphism: association with ethnic origin. J Hypertens 1994; 12: 955-7.
11. Jeunemaitre X, Lifton RP, Hunt SC, Williams RR, Lalouel JM. Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension. Nat Genet 1992; 1: 72-5.
12. Gu XX, Spaepen M, Guo C, Fagard R, Amery A, Lijnen P etal. Lack of association between the I/D polymorphism of the angiotensin-converting enzyme gene and essential hypertension in a Belgian population. J Hum Hypertens 1994; 8: 683-5.
13. Tsai CT, Fallin D, Chiang FT, Hwang JJ, Lai LP, Hsu KL etal. Angiotensinogen gene haplotype and hypertension: interaction with ACE gene I allele. Hypertension 2003; 41: 9-15.