Short-term oral nutritional intervention with protein and vitamin D decreases falls in malnourished older adults

Journal of the American Geriatrics Society

Volumn 60, Issue 4, 2012, Pages 691-699

  Neelemaat, Floor ^a,b,c   Lips, Paul ^b,c   Bosmans, Judith E ^a,c   Thijs, Abel ^b   Seidell, Jaap C ^a,c   Van Bokhorst de Van Der Schueren, Marian A E ^a,b,c  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Elderly patients; Energy; Falls; Nutritional intervention; Protein; RCT; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL;

ADULT; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; CALORIC INTAKE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; FALLING; FAT FREE MASS; FEMALE; HAND GRIP; HOSPITAL ADMISSION; HUMAN; MALE; MALNUTRITION; PHYSICAL ACTIVITY; PROTEIN INTAKE; RANDOMIZED CONTROLLED TRIAL; TELECONSULTATION;

ACCIDENTAL FALLS; ADMINISTRATION, ORAL; AGED; DIETARY PROTEINS; DIETARY SUPPLEMENTS; FEMALE; FOLLOW-UP STUDIES; FRACTURES, BONE; HUMANS; INCIDENCE; MALE; MALNUTRITION; MIDDLE AGED; NUTRITION THERAPY; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES; VITAMIN D; VITAMINS;

EID: 84859853102     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2011.03888.x     Document Type: Article

References (37)

1. Stel VS, Smit JH, Pluijm SM et al. Consequences of falling in older men and women and risk factors for health service use and functional decline. Age Ageing 2004;33:58-65. (Pubitemid 38111450)
2. Blake AJ, Morgan K, Bendall MJ et al. Falls by elderly people at home: Prevalence and associated factors. Age Ageing 1988;17:365-372. (Pubitemid 19028314)
3. Graafmans WC, Ooms ME, Hofstee HM et al. Falls in the elderly: A prospective study of risk factors and risk profiles. Am J Epidemiol 1996;143:1129-1136. (Pubitemid 26158109)
4. Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med 1988;319:1701-1707. (Pubitemid 19019577)
5. Kim JS, Wilson JM, Lee SR. Dietary implications on mechanisms of sarcopenia: Roles of protein, amino acids and antioxidants. J Nutr Biochem 2010;21:1-13.
6. Bischoff-Ferrari HA, Borchers M, Gudat F et al. Vitamin D receptor expression in human muscle tissue decreases with age. J Bone Miner Res 2004;19:265-269. (Pubitemid 38116740)
7. Chevalier S, Saoud F, Gray-Donald K et al. The physical functional capacity of frail elderly persons undergoing ambulatory rehabilitation is related to their nutritional status. J Nutr Health Aging 2008;12:721-726.
8. Tang BM, Eslick GD, Nowson C et al. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: A meta-analysis. Lancet 2007;370:657-666. (Pubitemid 47285316)
9. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC et al. Effect of vitamin D on falls: A meta-analysis. JAMA 2004;291:1999-2006. (Pubitemid 38544282)
10. Boonen S, Bischoff-Ferrari HA, Cooper C et al. Addressing the musculoskeletal components of fracture risk with calcium and vitamin D: A review of the evidence. Calcif Tissue Int 2006;78:257-270.
11. Vellas B, Conceicao J, Lafont C et al. Malnutrition and falls. Lancet 1990;336:1447.
12. Johnson CS. The association between nutritional risk and falls among frail elderly. J Nutr Health Aging 2003;7:247-250. (Pubitemid 36781684)
13. Milne AC, Potter J, Vivanti A et al. Protein and energy supplementation in elderly people at risk from malnutrition (Review). Cochrane Database Syst Rev 2009;CD003288.
14. Lauque S, Arnaud-Battandier F, Gillette S et al. Improvement of weight and fat-free mass with oral nutritional supplementation in patients with Alzheimer's disease at risk of malnutrition: A prospective randomized study. J Am Geriatr Soc 2004;52:1702-1707. (Pubitemid 41709924)
15. McMurdo ME, Price RJ, Shields M et al. Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. J Am Geriatr Soc 2009;57:2239-2245.
16. Price R, Daly F, Pennington CR et al. Nutritional supplementation of very old people at hospital discharge increases muscle strength: A randomised controlled trial. Gerontology 2005;51:179-185. (Pubitemid 41094875)
17. Gray-Donald K, Payette H, Boutier V. Randomized clinical trial of nutritional supplementation shows little effect on functional status among freeliving frail elderly. J Nutr 1995;125:2965-2971.
18. Neelemaat F, Bosmans JE, Thijs A et al. Post-discharge nutritional support in malnourished elderly individuals improves functional limitations. J Am Med Dir Assoc 2011;12:295-301.
19. Neelemaat F, Thijs A, Seidell JC et al. Study protocol: Cost-effectiveness of transmural nutritional support in malnourished elderly patients in comparison with usual care. Nutr J 2010;9:6.
20. Dutch Nutrition Center. Nederlandse Voedingsmiddelentabel (Dutch Food Composition Table). The Hague, the Netherlands: Dutch Nutrition Center, 2001.
21. Towards an Adequate Intake of Vitamin D. The Hague, the Netherlands: Health Council of the Netherlands, 2008.
22. Kyle UG, Bosaeus I, De Lorenzo AD et al. Bioelectrical impedance analysis - part I: Review of principles and methods. Clin Nutr 2004;23:1226-1243. (Pubitemid 39243041)
23. Kyle UG, Bosaeus I, De Lorenzo AD et al. Bioelectrical impedance analysis - part II: Utilization in clinical practice. Clin Nutr 2004;23:1430-1453. (Pubitemid 39517638)
24. Mathiowetz V, Kashman N, Volland G et al. Grip and pinch strength: Normative data for adults. Arch Phys Med Rehabil 1985;66:69-74. (Pubitemid 15134048)
25. Kriegsman DM, Deeg DJ, van Eijk JT et al. Do disease specific characteristics add to the explanation of mobility limitations in patients with different chronic diseases? A study in the Netherlands. J Epidemiol Community Health 1997;51:676-685. (Pubitemid 28014245)
26. Glass TA. Conjugating the "tenses" of function: Discordance among hypothetical, experimental, and enacted function in older adults. Gerontologist 1998;38:101-112. (Pubitemid 28128346)
27. Guralnik JM, Simonsick EM, Ferrucci L et al. A short physical performance battery assessing lower extremity function: association with selfreported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85-M94. (Pubitemid 24100267)
28. Wicherts IS, van Schoor NM, Boeke AJ et al. Vitamin D status predicts physical performance and its decline in older persons. J Clin Endocrinol Metab 2007;92:2058-2065. (Pubitemid 46997101)
29. The prevention of falls in later life. A report of the Kellogg International Work Group on the prevention of falls by the elderly. Dan Med Bull 1987;34 (Suppl 4):1-24.
30. Nevitt MC, Cummings SR, Kidd S et al. Risk factors for recurrent nonsyncopal falls. A prospective study. JAMA 1989;261:2663-2668. (Pubitemid 19127961)
31. Tinetti ME, Doucette J, Claus E et al. Risk factors for serious injury during falls by older persons in the community. J Am Geriatr Soc 1995;43:1214-1221.
32. Tromp AM, Smit JH, Deeg DJ et al. Predictors for falls and fractures in the Longitudinal Aging Study Amsterdam. J Bone Miner Res 1998;13:1932-1939. (Pubitemid 28535851)
33. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB et al. Fall prevention with supplemental and active forms of vitamin D: A meta-analysis of randomised controlled trials. BMJ 2009;339:b3692.
34. van Schoor NM, Visser M, Pluijm SM et al. Vitamin D deficiency as a risk factor for osteoporotic fractures. Bone 2008;42:260-266.
35. Ross AC, Manson JE, Abrams SA et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: What clinicians need to know. J Clin Endocrinol Metab 2011;96: 53-58.
36. Lips P, Binkley N, Pfeifer M et al. Once-weekly dose of 8400 IU vitamin D(3) compared with placebo: Effects on neuromuscular function and tolerability in older adults with vitamin D insufficiency. Am J Clin Nutr 2010;91:985-991.
37. Rufenacht U, Ruhlin M, Wegmann M et al. Nutritional counseling improves quality of life and nutrient intake in hospitalized undernourished patients. Nutrition 2010;26:53-60.