Gastric Acid Suppression and Clostridium difficile Infection: Is There a Causal Connection?

Clinical Gastroenterology and Hepatology

Volumn 10, Issue 5, 2012, Pages 564-

  Khanna, Sahil ^a   Pardi, Darrell S ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

CLOSTRIDIUM DIFFICILE INFECTION; HUMAN; INFECTION RISK; LETTER; STOMACH ACID;

CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; HUMANS; PROTON PUMP INHIBITORS;

EID: 84859840401     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2012.01.013     Document Type: Letter

References (3)

1. Deshpande A., Pant C., Pasupuleti V., et al. Association between proton pump inhibitor therapy and Clostridium difficile infection in a meta-analysis. Clin Gastroenterol Hepatol 2012, 12:225-233.
2. Kyne L., Sougioultzis S., McFarland L.V., et al. Underlying disease severity as a major risk factor for nosocomial Clostridium difficile diarrhea. Infect Control Hosp Epidemiol 2002, 23:653-659.
3. Pépin J., Saheb N., Coulombe M.A., et al. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec. Clin Infect Dis 2005, 41:1254-1260.