Analysis and evaluation of the impurity of felodipine and its tablets

Yaoxue Xuebao

Volumn 47, Issue 2, 2012, Pages 223-228

  Zhang, Na ^a   Yu, Li Ju ^a   Li, Jie ^a   Tong, Jun Wei ^b   Meng, Jie ^b   Zhang, Qi Ming ^a   Shi, Ya Qin ^a  

^a NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Felodipine; Impurity; Toxicity

Indexed keywords

1 [DIMETHYL 4 (2,3 DICHLOROPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; 2 [ETHYL METHYL 4 (2,3 DICHLOROPHENYL) 2,6 DIMETHYLPYRIDINE 3,5 DICARBOXYLATE; 3 [DIETHYL 4 (2,3 DICHLOROPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; CARBOXYLIC ACID DERIVATIVE; FELODIPINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG IMPURITY; DRUG ISOLATION; DRUG MANUFACTURE; DRUG QUALITY; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; TABLET FORMULATION; TERATOGENICITY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ZEBRA FISH;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM CHANNEL BLOCKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; FELODIPINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; QUALITY CONTROL; SPECTROPHOTOMETRY, INFRARED; TABLETS; TANDEM MASS SPECTROMETRY; ZEBRAFISH;

EID: 84859835883     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Chinese Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China [S]. 2010 ed. Vol II. Beijing: China Medico-Pharmaceutical Science and Technology Publishing House, 2010: 453.
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5. Hu CQ. Current situation and the trend in impurity control of chemical drugs [J]. Sci Sin B, 2010, 40: 679-687.