Unrequested findings on cardiac computed tomography: Looking beyond the heart

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Buckens, Constantinus F ^a   Verkooijen, Helena M ^a   Gondrie, Martijn J ^a   Jairam, Pushpa ^a   Mali, Willem P ^a   van der Graaf, Yolanda ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; CARDIAC COMPUTER ASSISTED TOMOGRAPHY; CARDIAC IMAGING; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ELECTRON BEAM TOMOGRAPHY; FEMALE; HUMAN; HYPERTENSION; INCIDENTAL FINDING; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; OBSERVATIONAL STUDY; PREVALENCE; PUBLICATION; RETROSPECTIVE STUDY; REVIEW; RISK FACTOR; SMOKING; SYSTEMATIC REVIEW; THORAX PAIN; CARDIOVASCULAR DISEASE; HEART; RADIOGRAPHY; REGRESSION ANALYSIS;

CARDIOVASCULAR DISEASES; HEART; HUMANS; INCIDENTAL FINDINGS; REGRESSION ANALYSIS; RISK FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84859825970     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032184     Document Type: Review

References (44)

1. Garvey CJ, Hanlon R, (2002) Computed tomography in clinical practice. BMJ 324 (7345): 1077-1080.
2. Scrutinio D, Giannuzzi P, (2008) Comorbidity in patients undergoing coronary artery bypass graft surgery: impact on outcome and implications for cardiac rehabilitation. Eur J Cardiovasc Prev Rehabil 15 (4): 379-385.
3. Smith-Bindman R, (2010) Is Computed Tomography Safe? N Engl J Med. Jul 1; 363 (1): 1-4.
4. Brenner DJ, Hricak H, (2010) Radiation exposure from medical imaging: time to regulate? JAMA 304 (2): 208-209.
5. Hillman BJ, Goldsmith JC, (2010) The Uncritical Use of High-Tech Medical Imaging. N Engl J Med. Jul 1; 363 (1): 4-6.
6. Mettler FA Jr, Bhargavan M, Faulkner K, Gilley DB, Gray JE, et al. (2009) Radiologic and nuclear medicine studies in the United States and worldwide: frequency, radiation dose, and comparison with other radiation sources-1950-2007. Radiology 253 (2): 520-531.
7. Orme NM, Fletcher JG, Siddiki HA, Harmsen WS, O'Byrne MM, et al. (2010) Incidental findings in imaging research: evaluating incidence, benefit, and burden. Arch Intern Med 170 (17): 1525-1532.
8. Budoff MJ, Gopal A, (2007) Incidental findings on cardiac computed tomography. Should we look? J Cardiovasc Comput Tomogr 1 (2): 97-105.
9. Sosnouski D, Bonsall RP, Mayer FB, Ravenel JG, (2007) Extracardiac findings at cardiac CT: a practical approach. J Thorac Imaging 22 (1): 77-85.
10. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, et al. (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. Apr 19; 283 (15): 2008-12.
11. Hussain A, Gordon-Dixon A, Almusawy H, Sinha P, Desai A, (2009) The incidence and outcome of incidental breast lesions detected by computed tomography. Ann R Coll Surg Engl. Mar; 92 (2): 124-6.
12. Quentin M, Kropil P, Steiner S, Lanzman RS, Blondin D, et al. (2010) [Prevalence and clinical significance of incidental cardiac findings in non-ECG-gated chest CT scans.]. Radiologe Jan; 51 (1): 59-64.
13. Vandenbroucke JP, von EE, Altman DG, Gotzsche PC, Mulrow CD, et al. (2007) Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Epidemiology 18 (6): 805-835.
14. von EE, Altman DG, Egger M, Pocock SJ, Gotzsche PC, et al. (2008) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 61 (4): 344-349.
15. R Development Core Team (2011) A Language and Environment for Statistical Computing. ISBN 3-900051-07-0, available: http://www.R-project.org/.
16. Viechtbauer W, (2010) Conducting meta-analyses in R with the metafor package. Journal of Statistical Software 36 (3): 1-48.
17. Higgins JP, Thompson SG, (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21 (11): 1539-1558.
18. DerSimonian R, Laird N, (1986) Meta-analysis in clinical trials. Control Clin Trials 7 (3): 177-188.
19. Koonce J, Schoepf JU, Nguyen SA, Northam MC, Ravenel JG, (2009) Extra-cardiac findings at cardiac CT: experience with 1,764 patients. Eur Radiol 19 (3): 570-576.
20. Law YM, Huang J, Chen K, Cheah FK, Chua T, (2008) Prevalence of significant extracoronary findings on multislice CT coronary angiography examinations and coronary artery calcium scoring examinations. J Med Imaging Radiat Oncol 52 (1): 49-56.
21. Schragin JG, Weissfeld JL, Edmundowicz D, Strollo DC, Fuhrman CR, (2004) Non-cardiac findings on coronary electron beam computed tomography scanning. J Thorac Imaging 19 (2): 82-86.
22. Greenberg-Wolff I, Uliel L, Goitein O, Shemesh J, Rozenman J, et al. (2008) Extra-cardiac findings on coronary computed tomography scanning. Isr Med Assoc J 10 (11): 806-808.
23. Kirsch J, Araoz PA, Steinberg FB, Fletcher JG, McCollough CH, et al. (2007) Prevalence and significance of incidental extracardiac findings at 64-multidetector coronary CTA. J Thorac Imaging 22 (4): 330-334.
24. Mueller J, Jeudy J, Poston R, White CS, (2007) Cardiac CT angiography after coronary bypass surgery: prevalence of incidental findings. AJR Am J Roentgenol 189 (2): 414-419.
25. Hunold P, Schmermund A, Seibel RM, Gronemeyer DH, Erbel R, (2001) Prevalence and clinical significance of accidental findings in electron-beam tomographic scans for coronary artery calcification. Eur Heart J 22 (18): 1748-1758.
26. Kim JW, Kang EY, Yong HS, Kim YK, Woo OH, et al. (2009) Incidental extracardiac findings at cardiac CT angiography: comparison of prevalence and clinical significance between precontrast low-dose whole thoracic scan and postcontrast retrospective ECG-gated cardiac scan. Int J Cardiovasc Imaging 25 (Suppl 1): 75-81.
27. Aglan I, Jodocy D, Hiehs S, Soegner P, Frank R, et al. (2010) Clinical relevance and scope of accidental extracoronary findings in coronary computed tomography angiography: A cardiac versus thoracic FOV study. Eur J Radiol. Apr 74 (1): 166-74.
28. Machaalany J, Yam Y, Ruddy TD, Abraham A, Chen L, et al. (2009) Potential clinical and economic consequences of noncardiac incidental findings on cardiac computed tomography. J Am Coll Cardiol 54 (16): 1533-1541.
29. Lazoura O, Vassiou K, Kanavou T, Vlychou M, Arvanitis DL, et al. (2010) Incidental non-cardiac findings of a coronary angiography with a 128-slice multi-detector CT scanner: should we only concentrate on the heart? Korean J Radiol 11 (1): 60-68.
30. Mueller J, Jeudy J, Poston R, White CS, (2007) Cardiac CT angiography after coronary bypass surgery: prevalence of incidental findings. AJR Am J Roentgenol 189 (2): 414-419.
31. MacMahon H, Austin JH, Gamsu G, Herold CJ, Jett JR, et al. (2005) Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology 237 (2): 395-400.
32. Kirsch J, Araoz PA, Steinberg FB, Fletcher JG, McCollough CH, et al. (2007) Prevalence and significance of incidental extracardiac findings at 64-multidetector coronary CTA. J Thorac Imaging 22 (4): 330-334.
33. Chia PL, Kaw G, Wansaicheong G, Ho KT, (2009) Prevalence of non-cardiac findings in a large series of patients undergoing cardiac multi-detector computed tomography scans. Int J Cardiovasc Imaging 25 (5): 537-543.
34. Lehman SJ, Abbara S, Cury RC, Nagurney JT, Hsu J, et al. (2009) Significance of cardiac computed tomography incidental findings in acute chest pain. Am J Med 122 (6): 543-549.
35. Onuma Y, Tanabe K, Nakazawa G, Aoki J, Nakajima H, et al. (2006) Noncardiac findings in cardiac imaging with multidetector computed tomography. J Am Coll Cardiol 48 (2): 402-406.
36. Burt JR, Iribarren C, Fair JM, Norton LC, Mahbouba M, et al. (2008) Incidental findings on cardiac multidetector row computed tomography among healthy older adults: prevalence and clinical correlates. Arch Intern Med 168 (7): 756-761.
37. Elias-Smale SE, Proenca RV, Koller MT, Kavousi M, van Rooij FJ, et al. (2010) Coronary calcium score improves classification of coronary heart disease risk in the elderly: the Rotterdam study. J Am Coll Cardiol 56 (17): 1407-1414.
38. Johnson KM, Dowe DA, (2010) The detection of any coronary calcium outperforms Framingham risk score as a first step in screening for coronary atherosclerosis. AJR Am J Roentgenol 194 (5): 1235-1243.
39. Greenland P, Bonow RO, Brundage BH, Budoff MJ, Eisenberg MJ, et al. (2007) ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: A report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography). Circulation 115 (3): 402-426.
40. Venkatesh V, You JJ, Landry DJ, Ellins ML, Sheth T, (2010) Extracardiac findings in cardiac computed tomographic angiography in patients at low to intermediate risk for coronary artery disease. Can Assoc Radiol J 61 (5): 286-290.
41. Dewey M, Schnapauff D, Teige F, Hamm B, (2007) Non-cardiac findings on coronary computed tomography and magnetic resonance imaging. Eur Radiol 17 (8): 2038-2043.
42. Kawano Y, Tamura A, Goto Y, Shinozaki K, Zaizen H, et al. (2007) Incidental detection of cancers and other non-cardiac abnormalities on coronary multislice computed tomography. Am J Cardiol 99 (11): 1608-1609.
43. Haller S, Kaiser C, Buser P, Bongartz G, Bremerich J, (2006) Coronary artery imaging with contrast-enhanced MDCT: extracardiac findings. AJR Am J Roentgenol 187 (1): 105-110.
44. Horton KM, Post WS, Blumenthal RS, Fishman EK, (2002) Prevalence of significant noncardiac findings on electron-beam computed tomography coronary artery calcium screening examinations. Circulation 106 (5): 532-534.