Quantitative comparison of clopidogrel 600 mg, prasugrel and ticagrelor, against clopidogrel 300 mg on major adverse cardiovascular events and bleeding in coronary stenting: Synthesis of CURRENT-OASIS-7, TRITON-TIMI-38 and PLATO

International Journal of Cardiology

Volumn 158, Issue 2, 2012, Pages 181-185

  Nijjer, Sukhjinder S ^a   Davies, Justin E ^a   Francis, Darrel P ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; PRASUGREL; TICAGRELOR;

ANGIOPLASTY; BLEEDING; CARDIOVASCULAR DISEASE; CORONARY STENT; DECISION MAKING; DRUG SYNTHESIS; HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; SYSTEMATIC REVIEW;

EID: 84859804214     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2011.12.046     Document Type: Editorial

References (22)

1. J.J. Thebault, G. Kieffer, and R. Cariou Single-dose pharmacodynamics of clopidogrel Semin Thromb Hemost 25 Suppl 2 1999 3 8
2. P.A. Gurbel, K.P. Bliden, B.L. Hiatt, and C.M. O'Connor Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity Circulation 107 23 2003 2908 2913
3. T. Bauer, H.J. Bouman, and J.W. van Werkum Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis BMJ 343 2011 d4588
4. J.-H. Jung, P.-K. Min, and S.-H. Lee Clopidogrel pretreatment before primary percutaneous coronary stenting in patients with acute ST-segment elevation myocardial infarction: comparison of high loading dose (600 mg) versus low loading dose (300 mg) Coron Artery Dis 20 2 2009 150 154
5. F. Mangiacapra, O. Muller, and A. Ntalianis Comparison of 600 versus 300-mg Clopidogrel loading dose in patients with ST-segment elevation myocardial infarction undergoing primary coronary angioplasty Am J Cardiol 106 9 2010 1208 1211
6. G. Dangas, R. Mehran, and G. Guagliumi Role of clopidogrel loading dose in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty: results from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial J Am Coll Cardiol 54 15 2009 1438 1446
7. C.U. Choi, S.-W. Rha, and D.J. Oh Standard versus high loading doses of clopidogrel in Asian ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the Korea Acute Myocardial Infarction Registry Am Heart J 161 2 2011 373.e1-3 382.e1-3
8. G. Montalescot, G. Sideris, and C. Meuleman A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial J Am Coll Cardiol 48 5 2006 931 938
9. M. Abuzahra, M. Pillai, and A. Caldera Comparison of higher clopidogrel loading and maintenance dose to standard dose on platelet function and outcomes after percutaneous coronary intervention using drug-eluting stents Am J Cardiol 102 4 2008 401 403
10. L. Bonello, G. Lemesle, and A. De Labriolle Impact of a 600-mg loading dose of clopidogrel on 30-day outcome in unselected patients undergoing percutaneous coronary intervention Am J Cardiol 102 10 2008 1318 1322
11. G. Patti, G. Bárczi, and D. Orlic Outcome comparison of 600- and 300-mg loading doses of clopidogrel in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction results from the ARMYDA-6 MI (antiplatelet therapy for reduction of myocardial Damage during Angioplasty-Myocardial Infarction) Randomized Study J Am Coll Cardiol 58 15 2011 1592 1599
12. S.D. Wiviott, D. Trenk, and A.L. Frelinger Prasugrel Compared With High Loading- and Maintenance-Dose Clopidogrel in Patients With Planned Percutaneous Coronary Intervention Circulation 116 25 2007 2923 2932
13. L. Wallentin, R.C. Becker, and A. Budaj Ticagrelor versus clopidogrel in patients with acute coronary syndromes N Engl J Med 361 11 2009 1045 1057
14. S.R. Mehta, J.-F. Tanguay, and J.W. Eikelboom Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial Lancet 376 9748 2010 1233 1243
15. S.R. Mehta, J.-P. Bassand, and S. Chrolavicius Dose comparisons of clopidogrel and aspirin in acute coronary syndromes N Engl J Med 363 10 2010 930 942
16. S.D. Wiviott, E.M. Antman, and C.M. Gibson Evaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: design and rationale for the TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet InhibitioN with prasugrel Thrombolysis In Myocardial Infarction 38 (TRITON-TIMI 38) Am Heart J 152 4 2006 627 635
17. S.D. Wiviott, E. Braunwald, and C.H. McCabe Prasugrel versus clopidogrel in patients with acute coronary syndromes N Engl J Med 357 20 2007 2001 2015
18. P.G. Steg, S. James, and R.A. Harrington Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: a Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis Circulation 122 21 2010 2131 2141
19. J.M. Siller-Matula, K. Huber, and G. Christ Impact of clopidogrel loading dose on clinical outcome in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis Heart 97 2 2011 98 105
20. D.A. Morrow, S.D. Wiviott, and H.D. White Effect of the novel thienopyridine prasugrel compared with clopidogrel on spontaneous and procedural myocardial infarction in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel - thrombolysis in myocardial infarction 38 Circulation 119 21 2009 2758 2764
21. A.J. Coats, and L.G. Shewan Statement on Authorship and Publishing Ethics in the International Journal of Cardiology Int J Cardiol 153 2011 257 258
22. D.P. Francis Duration and magnitude of the effect of a single statin tablet in primary prevention of cardiovascular events Int J Cardiol 149 1 2011 102 107