An unusual case of nephrotic syndrome and glucosuria

American Journal of Kidney Diseases

Volumn 59, Issue 5, 2012, Pages 734-737

  Kwok, Sophie ^a   D'Agati, Vivette ^b   Anis, Kisra ^a   Jim, Belinda ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b College of Physicians and Surgeons ^*  (United States)

Author keywords

Glucosuria; nodular glomerulosclerosis; proteinuria; smoking

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FUROSEMIDE; GLUCOSE;

ADULT; ARTICLE; BLEEDING; BLOOD PRESSURE; BOWMAN CAPSULE; CASE REPORT; ERYTHROCYTE; GLOMERULOSCLEROSIS; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HUMAN; HYALINE DEGENERATION; HYPERTENSION; HYPERTENSION RETINOPATHY; IMMUNOFLUORESCENCE; KIDNEY BIOPSY; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY TUBULE BASEMENT MEMBRANE; LEG EDEMA; MALE; MICROANEURYSM; NEPHROSCLEROSIS; NEPHROTIC SYNDROME; PATHOLOGY; PROTEINURIA; RENAL DIABETES; RENAL REPLACEMENT THERAPY; SMOKING; ULTRASOUND; URINALYSIS;

BIOPSY; COMORBIDITY; DIABETIC NEPHROPATHIES; GLOMERULAR FILTRATION RATE; GLYCOSURIA; HUMANS; HYPERTENSION; KIDNEY; MALE; MIDDLE AGED; MUTATION; NEPHROTIC SYNDROME; PROTEINURIA; SMOKING; SODIUM-GLUCOSE TRANSPORTER 2;

EID: 84859798809     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2011.10.055     Document Type: Article

References (11)

1. Nasr SH, D'Agati VD. Nodular glomerulosclerosis in the nondiabetic smoker. J Am Soc Nephrol. 2007;18(7):2032-2036. (Pubitemid 47041068)
2. Herzenberg AM, Holden JK, Singh S, Magil AB. Idiopathic nodular glomerulosclerosis. Am J Kidney Dis. 1999;34(3):560-564. (Pubitemid 29413631)
3. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. Amore accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130(6):461-470. (Pubitemid 29135798)
4. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2005;28(suppl 1):S37-S42.
5. Alpers CE, Biava CG. Idiopathic lobular glomerulonephritis (nodular mesangial sclerosis): a distinct diagnostic entity. Clin Nephrol. 1989;32(2):68-74. (Pubitemid 19204967)
6. Markowitz GS, Lin J, Valeri AM, Avila C, Nasr SH, D'Agati VD. Idiopathic nodular glomerulosclerosis is a distinct clinicopathologic entity linked to hypertension and smoking. Hum Pathol. 2002;33(8):826-835. (Pubitemid 34983104)
7. Liang KV, Greene EL, Oei LS, Lewin M, Lager D, Sethi S. Nodular glomerulosclerosis: renal lesions in chronic smokers mimic chronic thrombotic microangiopathy and hypertensive lesions. Am J Kidney Dis. 2007;49(4):552-559. (Pubitemid 46441604)
8. Santer R, Calado J. Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target. Clin J Am Soc Nephrol. 2010;5(1):133-141.
9. Scholl-Burgi S, Santer R, Ehrich JH. Long-term outcome of renal glucosuria type 0: the original patient and his natural history. Nephrol Dial Transplant. 2004;19(9):2394-2396. (Pubitemid 39214139)
10. Schneider D, Gauthier B, Trachtman H. Hypercalciuria in children with renal glycosuria: evidence of dual renal tubular reabsorptive defects. J Pediatr. 1992;121(5, pt 1):715-719.
11. Vallon V, Platt KA, Cunard R, et al. SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 2011;22(1):104-112.