Nonhuman primate models of thrombosis

Thrombosis Research

Volumn 129, Issue SUPPL. 2, 2012, Pages

  Myers Jr , Daniel D ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE HEART INFARCTION; FATALITY; INCIDENCE; MORBIDITY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; REVIEW; THROMBOGENESIS; THROMBOSIS; VASCULITIS; VENOUS THROMBOEMBOLISM;

EID: 84859793997     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2012.02.037     Document Type: Article

References (74)

1. Anderson Jr FA, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med 1991;151:933-8.
2. Heit JA. The epidemiology of venous thromboembolism in the community. Arterioscler Thromb Vasc Biol 2008;28:370-2.
3. Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, et al. Heart disease and stroke statistics-2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2006;113:e85-151.
4. Jeremias A, Gruberg L, Patel J, Connors G, Brown DL. Effect of peripheral arterial disease on in-hospital outcomes after primary percutaneous coronary intervention for acute myocardial infarction. Am J Cardiol 2010;105:1268-71.
5. Bokarev IN, Popova LV. Atherothrombosis: state-of-the-art review and approaches to the problem. Klin Med (Mosk) 2008;86:4-12.
6. Sorensen HT, Horvath-Puho E, Pedersen L, Baron JA, Prandoni P. Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study. Lancet 2007;370:1773-9. (Pubitemid 350137491)
7. Lowe GD. Venous and arterial thrombosis: epidemiology and risk factors at various ages. Maturitas 2004;47:259-63. (Pubitemid 38520111)
8. Kikura M, Takada T, Sato S. Age- and sex-specific incidence, risk, and latency period of a perioperative acute thromboembolism syndrome (PATS). Thromb Haemost 2004;91:725-32. (Pubitemid 38477453)
9. Hull RD, Pineo GF, Raskob GE. The economic impact of treating deep vein thrombosis with low-molecular-weight heparin: outcome of therapy and health economy aspects. Haemostasis 1998;28(Suppl. 3):8-16. (Pubitemid 29049316)
10. Silverstein MD, Heit JA, Mohr DN, Petterson TM, O'Fallon WM, Melton III LJ. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med 1998;158:585-93. (Pubitemid 28144815)
11. Heit JA, Silverstein MD, Mohr DN, Petterson TM, Lohse CM, O'Fallon WM, et al. The epidemiology of venous thromboembolism in the community. Thromb Haemost 2001;86:452-63. (Pubitemid 32663974)
12. Henke PK, Comerota AJ. An update on etiology, prevention, and therapy of postthrombotic syndrome. J Vasc Surg 2011;53:500-9.
13. Libby P. Coronary artery injury and the biology of atherosclerosis: inflammation, thrombosis, and stabilization. Am J Cardiol 2000;86:3J-8J discussion J-9J.
14. Karnicki K, Komorowicz E, Fass DN, Owen WG, McBane II RD. Influence of anatomical location on arterial thrombosis. Arterioscler Thromb Vasc Biol 2002;22: 342-7. (Pubitemid 34130128)
15. Shah PK. Pathophysiology of coronary thrombosis: role of plaque rupture and plaque erosion. Prog Cardiovasc Dis 2002;44:357-68. (Pubitemid 34535157)
16. Kumar V, Abbas AK, Fausto N, Robbins SL, Cotran RS. Robbins and Cotran pathologic basis of disease. 7th ed. Philadelphia: Elsevier Saunders; 2005. p. 133.
17. Mackman N. Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol 2004;24:1015-22. (Pubitemid 38737825)
18. Nemerson Y. Tissue factor and hemostasis. Blood 1988;71:1-8. (Pubitemid 18050383)
19. Wagner DD, Frenette PS. The vessel wall and its interactions. Blood 2008;111: 5271-81.
20. Hrachovinova I, Cambien B, Hafezi-Moghadam A, Kappelmayer J, Camphausen RT, Widom A, et al. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat Med 2003;9:1020-5. (Pubitemid 37021781)
21. Furie B, Furie BC, Flaumenhaft R. A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion. Thromb Haemost 2001;86: 214-21. (Pubitemid 32666187)
22. Frenette PS, Denis CV, Weiss L, Jurk K, Subbarao S, Kehrel B, et al. P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. J Exp Med 2000;191:1413-22. (Pubitemid 30227127)
23. Shebuski RJ, Kilgore KS. Role of inflammatory mediators in thrombogenesis. J Pharmacol Exp Ther 2002;300:729-35. (Pubitemid 34164973)
24. Esmon CT. Crosstalk between inflammation and thrombosis. Maturitas 2008;61: 122-31.
25. Wakefield TW, Strieter RM, Prince MR, Downing LJ, Greenfield LJ. Pathogenesis of venous thrombosis: a new insight. Cardiovasc Surg 1997;5:6-15. (Pubitemid 27219718)
26. Gessamelte RV. Abhandlungen zur Wissenschaftlichen Medicin. Frankfurt: A M Von Meidinger Sohn; 1856.
27. Napoli C, De Nigris F, Pignalosa O, Lerman A, Sica G, Fiorito C, et al. In vivo veritas: thrombosis mechanisms in animal models. Scand J Clin Lab Invest 2006;66: 407-27. (Pubitemid 44221784)
28. New drug and biological drug products; evidence needed to demonstrate effectiveness of new drugs when human efficacy studies are not ethical or feasible. Final rule. Fed Regist., 67; 2002. p. 37988-98.
29. Investigational new drug safety reporting requirements for human drug and biological products and safety reporting requirements for bioavailability and bioequivalence studies in humans. Final rule. Fed Regist., 75; 2010. p. 59935-63.
30. National Institutes of Health (U.S.). Office of Laboratory Animal Welfare. Public Health Service policy on humane care and use of laboratory animals. Rev. August, 2002. Ed. Bethesda, MD: Office of Laboratory Animal Welfare, National Institutes of Health; 2002.
31. Guide for the care and use of laboratory animals. 8th ed. Washington, DC: National Academy Press; 2010.
32. Leadley Jr RJ, Chi L, Rebello SS,Gagnon A. Contribution of in vivomodels of thrombosis to the discovery and development of novel antithrombotic agents. J Pharmacol Toxicol Methods 2000;43:101-16. (Pubitemid 32057032)
33. Olejniczak KGP, Gunzel P, Bass R. Preclinical testing stratagies. Drug Inf J 2001;35: 321-36.
34. Todd ME, McDevitt E, Goldsmith EI. Blood-clotting mechanisms of nonhuman primates. Choice of the baboon model to simulate man. J Med Primatol 1972;1: 132-41.
35. Feingold HM, Pivacek LE, Melaragno AJ, Valeri CR. Coagulation assays and platelet aggregation patterns in human, baboon, and canine blood. Am J Vet Res 1986;47: 2197-9.
36. Harker LA, Malpass TW, Branson HE, Hessel II EA, Slichter SJ. Mechanismof abnormal bleeding in patients undergoing cardiopulmonary bypass: acquired transient platelet dysfunction associated with selective alpha-granule release. Blood 1980;56:824-34. (Pubitemid 11242975)
37. Melaragno AJ, Abdu W, Katchis R, Doty A, Valeri CR. Liquid and freeze preservation of baboon platelets. Cryobiology 1981;18:445-52. (Pubitemid 12215360)
38. Vecchione JJ, Melaragno AJ, Weiblen BJ, Halkett JA, Callow AD, Valeri CR. Repeated intravenous administrations of human albumin and human fibrinogen in the baboon: survival measurements. J Med Primatol 1982;11:91-105. (Pubitemid 13228786)
39. Valeri CR, Ragno G. The survival and function of baboon red blood cells, platelets, and plasma proteins: a review of the experience from 1972 to 2002 at the Naval Blood Research Laboratory, Boston, Massachusetts. Transfusion 2006;46:1S-42S. (Pubitemid 44107170)
40. Callow AD, Ledig CB, O'Donnell TF, Kelly JJ, Rosenthal D, Korwin S, et al. A primate model for the study of the interaction of 111In-labeled baboon platelets with Dacron arterial prostheses. Ann Surg 1980;191:362-6. (Pubitemid 10184252)
41. Abildgaard CF, Harrison J, Johnson CA. Comparative study of blood coagulation in nonhuman primates. J Appl Physiol 1971;30:400-5.
42. Kelly CA, Gleiser CA. Selected coagulation reference values for adult and juvenile baboons. Lab Anim Sci 1986;36:173-5. (Pubitemid 16118618)
43. Myers JD, Wrobleski SK, Henke PK, Wakefield TW. Coagulation Biology. In: Souba Wiley W, DWW, editors. Surgical Research. Academic Press; 2001. p. 989-99.
44. Hanson SR, Paxton LD, Harker LA. Iliac artery mural thrombus formation. Effect of antiplatelet therapy on 111In-platelet deposition in baboons. Arteriosclerosis 1986;6:511-8.
45. Hanson SR, Harker LA. Baboon models of acute arterial thrombosis. Thromb Haemost 1987;58:801-5. (Pubitemid 18020441)
46. Harker LA, Kelly AB, Hanson SR. Experimental arterial thrombosis in nonhuman primates. Circulation 1991;83:IV41-55.
47. Del Zoppo GJ, Copeland BR, Harker LA, Waltz TA, Zyroff J, Hanson SR, et al. Experimental acute thrombotic stroke in baboons. Stroke 1986;17:1254-65. (Pubitemid 17008967)
48. Del Zoppo GJ, Copeland BR, Waltz TA, Zyroff J, Plow EF, Harker LA. The beneficial effect of intracarotid urokinase on acute stroke in a baboon model. Stroke 1986;17:638-43. (Pubitemid 16066531)
49. Huang J, Mocco J, Choudhri TF, Poisik A, Popilskis SJ, Emerson R, et al. A modified transorbital baboon model of reperfused stroke. Stroke 2000;31:3054-63.
50. Nakai K, Welch KM, Meyer JS. Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil. J Neurol Neurosurg Psychiatry 1977;40:595-9. (Pubitemid 8192052)
51. Welch KM, Wang TP, Chabi E. Ischemia-induced seizures and cortical monoamine levels. Ann Neurol 1978;3:152-5.
52. Waltz AG. Clinical relevance of models of cerebral ischemia. Stroke 1979;10: 211-3. (Pubitemid 9111052)
53. Izuhara Y, Yamaoka N, Kodama H, Dan T, Takizawa S, Hirayama N, et al. A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates. J Cereb Blood Flow Metab 2010;30:904-12.
54. Johnson GJ, Griggs TR, Badimon L. The utility of animal models in the preclinical study of interventions to prevent human coronary artery restenosis: analysis and recommendations. On behalf of the Subcommittee on Animal, Cellular and Molecular Models of Thrombosis and Haemostasis of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost 1999;81:835-43.
55. Bush Jr HL, Jakubowski JA, Sentissi JM. Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model. J Vasc Surg 1988;7:275-83. (Pubitemid 18067328)
56. Hanson SR, Harker LA, Bjornsson TD. Effects of platelet-modifying drugs on arterial thromboembolism in baboons. Aspirin potentiates the antithrombotic actions of dipyridamole and sulfinpyrazone by mechanism(s) independent of platelet cyclooxygenase inhibition. J Clin Invest 1985;75:1591-9. (Pubitemid 15041453)
57. Harker LA, Hanson SR. Experimental arterial thromboembolism in baboons. Mechanism, quantitation, and pharmacologic prevention. J Clin Invest 1979;64: 559-60.
58. Hanson SR, Harker LA. Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone. Proc Natl Acad Sci U S A 1988;85:3184-8.
59. Hashi CK, Glickman MH. Preclinical results of a prosthetic, early-stick graft with functional endothelium. J Vasc Access 2011;12:231-8.
60. Hever T, Nemeth N, Brath E, Toth L, Kiss F, Sajtos E, et al. Morphological, hemodynamical and hemorheological changes of mature artificial saphenous arteriovenous shunts in the rat model. Microsurgery 2010;30:649-56.
61. Wakefield TW, Strieter RM, Schaub R, Myers DD, Prince MR, Wrobleski SK, et al. Venous thrombosis prophylaxis by inflammatory inhibition without anticoagulation therapy. J Vasc Surg 2000;31:309-24. (Pubitemid 30100041)
62. Myers Jr DD, Schaub R,Wrobleski SK, Londy III FJ, Fex BA, Chapman AM, et al. P-selectin antagonism causes dose-dependent venous thrombosis inhibition. Thromb Haemost 2001;85:423-9. (Pubitemid 32233012)
63. Myers D, Wrobleski S, Londy F, Fex B, Hawley A, Schaub R, et al. New and effective treatment of experimentally induced venous thrombosis with anti-inflammatory rPSGL-Ig. Thromb Haemost 2002;87:374-82. (Pubitemid 34232476)
64. Myers Jr DD, Wrobleski SK, Longo C, Bedard PW, Kaila N, Shaw GD, et al. Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation. Thromb Haemost 2007;97:400-7. (Pubitemid 46437802)
65. Meier TR, Myers Jr DD, Wrobleski SK, Zajkowski PJ, Hawley AE, Bedard PW, et al. Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation. Thromb Haemost 2008;99:343-51. (Pubitemid 351230965)
66. Dormehl IC, Jacobs DJ, Pretorius JP, Maree M, Franz RC. Baboon (Papio ursinus) model to study deep vein thrombosis using 111-indium-labeled autologous platelets. J Med Primatol 1987;16:27-38. (Pubitemid 17058298)
67. Palmerini T, Nedelman MA, Scudder LE, Nakada MT, Jordan RE, Smyth S, et al. Effects of abciximab on the acute pathology of blood vessels after arterial stenting in nonhuman primates. J Am Coll Cardiol 2002;40:360-6. (Pubitemid 34756300)
68. Krpski WC, Bass A, Kelly AB, Marzec UM, Hanson SR, Harker LA. Heparin-resistant thrombus formation by endovascular stents in baboons. Interruption by a synthetic antithrombin. Circulation 1990;82:570-7.
69. Rodman NF, Wolf RH, Mason RG. Venous thrombosis on prosthetic surfaces. Evolution and blood coagulation studies in a nonhuman primate model. Am J Pathol 1974;75:229-42.
70. Mason RG, Wolf RH, Zucker WH, Shinoda BA. Dynamics of thrombus formation on an artificial surface in vivo. Effects of antithrombotic agents. Am J Pathol 1976;82: 445-56.
71. Narayanaswamy M, Wright KC, Kandarpa K. Animal models for atherosclerosis, restenosis, and endovascular graft research. J Vasc Interv Radiol 2000;11:5-17. (Pubitemid 30067203)
72. Stewart GJ, Ritchie WG, Lynch PR. Venous endothelial damage produced by massive sticking and emigration of leukocytes. Am J Pathol 1974;74:507-32.
73. Hampton JW, Matthews C. Similarities between baboon and human blood clotting. J Appl Physiol 1966;21:1713-6.
74. Savage B, McFadden PR, Hanson SR, Harker LA. The relation of platelet density to platelet age: survival of low- and high-density 111indium-labeled platelets in baboons. Blood 1986;68:386-93. (Pubitemid 16050658)