Comparison of efficacy of letrozole and clomiphene citrate in ovulation induction for women with polycystic ovarian syndrome

HealthMED

Volumn 6, Issue 3, 2012, Pages 879-883

  Nazik, Hakan ^a   Kumtepe, Yakup ^b  

^a ADANA NUMUNE EDUCATION AND RESEARCH HOSPITAL   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Clomiphene citrate; Letrozole; Ovulation induction; PCOS

Indexed keywords

CLOMIFENE CITRATE; GONAPHENE; LETROZOLE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; MAJOR CLINICAL STUDY; OVARY FOLLICLE MATURATION; OVARY POLYCYSTIC DISEASE; OVULATION; OVULATION INDUCTION; PREGNANCY RATE; PROSPECTIVE STUDY; TREATMENT OUTCOME; TWIN PREGNANCY;

EID: 84859785368     PISSN: 18402291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Franks S. Poliycystic ovary sendrome. N Engl J Med 1995;333:853-861
2. Hananel H, Casper RF, Tulandi T. A new era in ovulation indution. Fertil Steril 2006;85:277-84
3. Li TC, Warren MA, Murphy C, Sargeant S, Cooke ID. A prospective, randomised, cross-over study comparing the effects of clomiphene citrate and cyclofenil on endometrial morphology in the luteal phase of normal fertile women. Br J Obstet Gynaecol 1992;99:1008-1013.
4. Mitwally MF, Casper RF. Use of aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate. Fertil Steril 2001;75:305-9.
5. Hamilton-Fairley D, Franks S, Common problems in induction of ovulation. Baillieres Clin Obstet Gynaecol 1990;4:609-25.
6. Mitwally MF, Casper RF. Aromatase inhibition: a novel method of ovulation induction in women with polycystic sendrome. Reprod Technol. 2000:10;244-247.
7. Broodie AM, Njar VJ. Aromatase inhibitors and breast canser. Semin Oncol 1996;46:4823-6.
8. Mitwally M, Casper R. Aromatase Inhibitors in ovulation induction. Semin Reprod Med 2004;22:61-78.
9. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril2004; 81:19-25
10. Kruger TF, Coetzee K. The role of sperm morphology in assisted reproduction. Hum Reprod Update. 1999 Mar-Apr;5(2):172-8. Review
11. Casper RF, Mitwally MF. Aromatase Inhibitors for Ovulation Induction. J Clin Endocrinol Metab 2006;91:760-771.
12. Buzdar A, Howell A. Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer. Clin Cancer Res 2001;7:2620-2635
13. Atay V, Cam C, Muhcu M, Cam M, Karateke A. Comparison of letrozole and clomiphene citrate in women with polycystic ovaries undergoing ovarian stimulation. J Int Med Res.2006;34:73-76.
14. Begum MR, Quadir E, Begum A, Begum RA, Begum M. Role of aromatase inhibitor in ovulation induction in patients with poor response to clomiphene citrate J Obstet Gynaecol Res. 2006;32: 502-6.
15. Bayar U, Basaran M, Kiran S, Coskun A, Gezer S. Use of an aromatase inhibitor in patients with polycystic ovary syndrome: a prospective randomized trial. Fertil Steril. 2006;86:1447-51.
16. Al-Omari, Sulaiman WR, Al-Hadithi N. Comparison of two aromatase inhibitors in women with clomiphene- resistant polycystic ovary syndrome. Int J Gynaecol Obstet. 2000:85;289-291.
17. Begum MR, Ferdous J, Begum A, Quadir E. Efficacy of aromatase inhibitor and clomiphene citrate in induction of ovulation in polycystic ovarian disease (PCOD). Fertil Steril 2009;92:853-7.
18. Badawy AM, Aal IA, Abulatta M. Clomiphene citrate or letrozole for ovulation induction in women with polycystic ovarian syndrome? A prospective randomized trial. Fertil Steril 2009;92:849-52.
19. Baruah B, Roy KK, Rahman SM, Kumar S, Sharma JB, Karmakar D. Endometrial effects of letrozole and clomiphene citrate in women with polycystic ovary syndrome using spiral artery Doppler. Arch Gynecol Obstet 2009;279:311-314.
20. He D, Jiang F. Meta-analysis of letrozole versus clomiphene citrate in polycystic ovary syndrome. Reprod Biomed Online. 2011;23(1):91-6.