Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection

Scientific Reports

Volumn 1, Issue , 2011, Pages

  Kasamatsu, Shinya ^a   Hachiya, Akira ^a   Fujimura, Tsutomu ^a   Sriwiriyanont, Penkanok ^b   Haketa, Keiichi ^a   Visscher, Marty O ^c   Kitzmiller, William J ^d   Bello, Alexander ^e   Kitahara, Takashi ^a   Kobinger, Gary P ^e   Takema, Yoshinori ^a  

^a KAO CORPORATION   (Japan)

^b 705 Engineering Research Center   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CINCINNATI   (United States)

^e UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; CARRIER PROTEIN; FIBRILLIN; GLYCOPROTEIN; MFAP4 PROTEIN, HUMAN; RECOMBINANT PROTEIN; SCLEROPROTEIN; SMALL INTERFERING RNA;

ANIMAL; ARTICLE; CUTANEOUS PARAMETERS; DRUG ANTAGONISM; DRUG EFFECT; ELASTICITY; FUNCTIONS OF THE SKIN AND ITS APPENDAGES; GENETICS; HOMEOSTASIS; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; RADIATION EXPOSURE; SKIN; ULTRAVIOLET RADIATION; XENOGRAFT;

ANIMALS; CARRIER PROTEINS; ELASTICITY; EXTRACELLULAR MATRIX PROTEINS; GLYCOPROTEINS; HOMEOSTASIS; HUMANS; MICE; MICROFILAMENT PROTEINS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SKIN; SKIN AGING; SKIN PHYSIOLOGICAL PHENOMENA; TRANSPLANTATION, HETEROLOGOUS; ULTRAVIOLET RAYS;

EID: 84859771720     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00164     Document Type: Article

References (60)

1. Crutzen, P. J. Ultraviolet on the increase. Nature 356, 104-105 (1992).
2. Slaper, H., Velders, G. J. M., Daniel, J. S., De, Gruijl, F. R. & Van der, Leun, J. C. Estimates of ozone depletion and skin cancer incidence to examine the Vienna Convention achievements. Nature 384, 256-258 (1996). (Pubitemid 26396972)
3. Scharffetter-Kochanek, K. et al. UV-induced reactive oxygen species in photocarcinogenesis and photoaging. Biol. Chem. 378, 1247-1257 (1997). (Pubitemid 27507540)
4. Nakagawa, H. Cutaneous aging processes. J. Japanese Cosmetic Science Society 24, 120-123 (2000).
5. Braverman, I. M. & Fonferko, E. Studies in cutaneous aging: 1. The elastic fiber network. J. Invest. Dermatol. 78, 434-443 (1982). (Pubitemid 12100911)
6. Uitto, J. Connective tissue biochemistry of aging dermis. Age-related alterations in collagen and elastin. Dermatol. Clin. 4, 433-446 (1986). (Pubitemid 16094938)
7. Schwartz, E. Connective tissue alterations in the skin of ultraviolet irradiated hairless mice. J. Invest. Dermatol. 91, 158-161 (1988).
8. Zheng, P. & Kligman, L. H. UVA-induced ultrastructural changes in hairless mouse skin: a comparison to UVB-induced damage. J. Invest. Dermatol. 100, 194-199 (1993). (Pubitemid 23053307)
9. Bernstein, E. F. et al. Enhanced elastin and fibrillin gene expression in chronically photodamaged skin. J. Invest. Dermato. l 103, 182-186 (1994). (Pubitemid 24234604)
10. Schwartz, E., Feinberg, E., Lebwohl, M., Mariani, T. J. & Boyd, C. D. Ultraviolet radiation increases tropoelastin accumulation by a post-transcriptional mechanism in dermal fibroblasts. J. Invest. Dermatol. 105, 65-69 (1995).
11. Bernstein, E. F. & Uitto, J. The effect of photodamage on dermal extracellular matrix. Clin. Dermatol. 14, 143-151 (1996). (Pubitemid 26130198)
12. Starcher, B., Pierce, R. & Hinek, A. UVB irradiation stimulates deposition of new elastic fibers by modified epithelial cells surrounding the hair follicles and sebaceous glands in mice. J. Invest. Dermatol. 112, 450-455 (1999). (Pubitemid 29171934)
13. Kambayashi, H. et al. Epidermal changes caused by chronic low-dose UV irradiation induce wrinkle formation in hairless mouse. J. Dermatol. Sci. 27, S19-S25 (2001).
14. Kambayashi, H., Odake, Y., Takada, K., Funasaka, Y. & Ichihashi, M. Involvement of changes in stratum corneum keratin in wrinkle formation by chronic ultraviolet irradiation in hairless mice. Exp. Dermatol. 12, 22-27 (2003). (Pubitemid 37526845)
15. Sano, T. et al. The formation of wrinkles caused by transition of keratin intermediate filaments after repetitive UVB exposure. Arch. Dermatol. Res. 296, 359-365 (2005). (Pubitemid 40310808)
16. Hachiya, A. et al. Mechanistic effects of long-term ultraviolet B irradiation induce epidermal and dermal changes in human skin xenografts. Am. J. Pathol. 174, 401-413 (2009).
17. Oxlund, H., Manscho, J. & Viidik, A. The role of elastin in the mechanical properties of skin. J. Biomech. 21, 213-218 (1988). (Pubitemid 18095753)
18. Imayama, S. & Braverman, I. M. A hypothetical explanation for the aging of skin. Chronologic alteration of the three-dimensional arrangement of collagen and elastic fibers in connective tissue. Am. J. Pathol. 134, 1019-1025 (1989). (Pubitemid 19142885)
19. Labat-Robert, J., Fourtanier, A., Boyer-Lafargur, B. & Robert, L. Age dependent increase of elastase type protease activity in mouse skin. Effect of UV-irradiation. J. Photochem. Photobiol. B. 57, 113-118 (2000).
20. Tsukahara, K. et al. Selective inhibition of skin fibroblast elastase elicits a concentration-dependent prevention of ultraviolet B-induced wrinkle formation. J. Invest. Dermatol. 117, 671-677 (2001). (Pubitemid 32955596)
21. Tsuji, N., Moriwaki, S., Suzuki, Y., Takema, Y. & Imokawa, G. The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity. Photochem. Photobiol. 74, 283-290 (2001).
22. Chung, J. H. et al. Ultraviolet modulation of human macrophage metalloelastase in human skin in vivo. J. Invest. Dermatol. 119, 507-512 (2002).
23. Mera, S. L., Lovell, C. R., Jones, R. R. & Davies, J. D. Elastic fibres in normal and sun-damaged skin: an immunohistochemical study. Br. J. Dermatol. 117, 21-27 (1987). (Pubitemid 17096131)
24. Montagna, W., Kirchner, S. & Carlisle, K. Histology of sun-damaged human skin. J. Am. Acad. Dermatol. 21, 907-918 (1989). (Pubitemid 19268632)
25. Warren, R. et al. Age, sunlight, and facial skin: a histologic and quantitative study. J. Am. Acad. Dermatol. 25, 751-760 (1991).
26. Seo, J. Y. et al., Ultraviolet radiation increases tropoelastin mRNA expression in the epidermis of human skin in vivo. J. Invest. Dermatol. 116, 915-919 (2001).
27. Sakai, L. Y., Keene, D. R. & Engvall, E. Fibrillin, A new 350-kD glycoprotein, is a component of extracellular microfibrils. J. Cell Biol. 103, 2499-2509 (1986). (Pubitemid 17216674)
28. Hollister, D. W., Godfrey, M., Sakai, L. Y. & Pyeritz, R. E. Immunohistologic abnormalities of the microfibrillar-fiber system in the Marfan syndrome. N. Engl. J. Med. 323, 152-159 (1990). (Pubitemid 20219943)
29. Kielty, C. M., Sherratt, M. J. & Shuttleworth, C. A. Elastic fibres. J. Cell Sci. 115, 2817-2828 (2002).
30. Wagenseil, J. E. & Mecham, R. P. New insights into elastic fiber assembly. Birth Defects Res. C. 81, 229-240 (2007). (Pubitemid 351186172)
31. Gray, W. R., Sandberg, L. B. & Foster, J. A. Molecular model for elastin structure and function. Nature 246, 461-466 (1973).
32. Narayanan, A. S., Page, R. C., Kuzan, F. & Cooper, C. G. Elastin cross-linking in vitro. Studies on factors influencing the formation of desmosines by lysyl oxidase action on tropoelastin. Biochem. J. 173, 857-862 (1978). (Pubitemid 9010978)
33. Bellingham, C. M., Woodhouse, K. A., Robson, P., Rothstein, S. J. & Keeley, F. W. Self-aggregation characteristics of recombinantly expressed human elastin polypeptides. Biochim. Biophys. Acta. 1550, 6-19 (2001). (Pubitemid 33153060)
34. Toonkool, P., Jensen, S. A., Maxwell, A. L. & Weiss, A. S. Hydrophobic domains of human tropoelastin interact in a context-dependent manner. J. Biol. Chem. 276, 44575-44580 (2001).
35. Zhao, Z. et al. The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patients. Hum. Mol. Genet. 4, 589-597 (1995).
36. Kobayashi, R. et al. Isolation and characterization of a new 36-kDa microfibrilassociated glycoprotein from porcine aorta. J. Biol. Chem. 264, 17437-17444 (1989). (Pubitemid 19255580)
37. Kobayashi, R., Mizutani, A. & Hidaka, H. Isolation and characterization of a 36-kDa microfibril-associated glycoprotein by the newly synthesized isoquinolinesulfonamide affinity chromatography. Biochem. Biophys. Res. Commun. 198, 1262-1266 (1994). (Pubitemid 24172832)
38. Toyoshima, T. et al. Ultrastructural distribution of 36-kD microfibril-associated glycoprotein (MAGP-36) in human and bovine tissues. J. Histochem. Cytochem. 47, 1049-1056 (1999). (Pubitemid 29379904)
39. Toyoshima, T., Nishi, N., Kusama, H., Kobayashi, R. & Itano, T. 36-kDa microfibril-associated glycoprotein (MAGP-36) is an elastin-binding protein increased in chick aortae during development and growth. Exp. Cell. Res. 307, 224-230 (2005). (Pubitemid 40732748)
40. Hirano, E. et al. Expression of 36-kDa microfibril-associated glycoprotein (MAGP-36) in human keratinocytes and its localization in skin. J. Dermatol. Sci. 28, 60-67 (2002). (Pubitemid 34251061)
41. Brassart, B. et al. Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts. J. Biol. Chem. 276, 5222-5227 (2001). (Pubitemid 37371419)
42. Duca, L. et al. The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J. Biol. Chem. 282, 12484-12491 (2007). (Pubitemid 47100624)
43. Tsutsui, K. et al. ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation. J. Biol. Chem. 285, 4870-4882 (2010).
44. Horiguchi, M. et al. Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase. Proc. Natl. Acad. Sci. USA 106, 19029-19034 (2009).
45. Nakamura, T. et al. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature 415, 171-175 (2002). (Pubitemid 34059518)
46. Hirai, M. et al. Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly. EMBO J. 26, 3283-3295 (2007). (Pubitemid 47123533)
47. Katsuta, Y. et al. Fibulin-5 accelerates elastic fibre assembly in human skin fibroblasts. Exp. Dermatol. 17, 837-842 (2008).
48. Choudhury, R. et al., Differential regulation of elastic fiber formation by fibulin-4 and-5. J. Biol. Chem. 284, 24553-24567 (2009).
49. Parsi, M. K., Adams, J. R., Whitelock, J. & Gibson, M. A. LTBP-2 has multiple heparin/heparan sulfate binding sites. Matrix Biol. 29, 393-401 (2010).
50. Kadoya, K. et al., Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis. Br. J. Dermatol. 153, 607-612 (2005). (Pubitemid 41248221)
51. Watson, R. E. et al., Fibrillin-rich microfibrils are reduced in photoaged skin. Distribution at the dermal-epidermal junction. J. Invest. Dermatol. 112, 782-787 (1999). (Pubitemid 29220723)
52. Coquerel, B. et al. Elastin-derived peptides: matrikines critical for glioblastoma cell aggressiveness in a 3-D system. Glia 57, 1716-1726 (2009).
53. Park, J. B., Kong, C. G., Suhl, K. H., Chang, E. D. & Riew, K. D. The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis. Clin. Orthop. Surg. 1, 81-89 (2009).
54. Sherratt, M. J. et al., Low-dose ultraviolet radiation selectively degrades chromophore-rich extracellular matrix components. J. Pathol. 222, 32-40 (2010).
55. Moon, S. E., Dame, M. K., Remick, D. R., Elder, J. T. & Varani, J. Induction of matrixmetalloproteinase-1 (MMP-1) during epidermal invasion of the stroma in human skin organ culture: keratinocyte stimulation of fibroblast MMP-1 production. Br. J. Cancer. 85, 1600-1605 (2001). (Pubitemid 34001596)
56. Fisher, G. J. et al. Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. Am. J. Pathol. 174, 101-114 (2009).
57. Watson, D. J., Kobinger, G. P., Passini, M. A., Wilson, J. M. & Wolfe, J. H. Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins. Mol. Ther. 5, 528-537 (2002). (Pubitemid 34546082)
58. Croyle, M. A. et al. PEGylation of a vesicular stomatitis virus G pseudotyped lentivirus vector prevents inactivation in serum. J. Virol. 78, 912-921 (2004). (Pubitemid 38067612)
59. Hachiya, A. et al. Gene transfer in human skin with different pseudotyped HIVbased vectors. Gene Ther. 14, 648-656 (2007). (Pubitemid 46585624)
60. Takema, Y., Yorimoto, Y., Kawai, M. & Imokawa, G. Age-related changes in the elastic properties and thickness of human facial skin. Br. J. Dermatol. 131, 641-648 (1994). (Pubitemid 24344048)