-
1
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couédic JP, Staerk J, Delhommeau F, Lacout C, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-8.
-
(2005)
Nature.
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
le Couédic, J.P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
-
2
-
-
79952042862
-
Targeting myeloproliferative neoplasms with JAK inhibitors
-
Pardanani A, Tefferi A. Targeting myeloproliferative neoplasms with JAK inhibitors. Curr Opin Hematol. 2011;18:105-10.
-
(2011)
Curr Opin Hematol.
, vol.18
, pp. 105-110
-
-
Pardanani, A.1
Tefferi, A.2
-
3
-
-
42449124578
-
Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
-
Tefferi A, Lasho TL, Huang J, Finke C, Mesa RA, Li CY, et al. Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival. Leukemia. 2008;22:756-61.
-
(2008)
Leukemia.
, vol.22
, pp. 756-761
-
-
Tefferi, A.1
Lasho, T.L.2
Huang, J.3
Finke, C.4
Mesa, R.A.5
Li, C.Y.6
-
4
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S, Kantarjian H, Mesa RA, Pardanani AD, Cortes-Franco J, Thomas DA, et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med. 2010;363:1117-27.
-
(2010)
N Engl J Med.
, vol.363
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
Mesa, R.A.3
Pardanani, A.D.4
Cortes-Franco, J.5
Thomas, D.A.6
-
5
-
-
80051667101
-
Results of a randomized study of the JAK inhibitor ruxolitinib (INC424) vs best available therapy (BAT) in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) or post-essential thrombocythemiamyelofibrosis (PET-MF)
-
Abstract LBA6501
-
Harrison CN, Kiladjian J, Al-Ali HK, Gisslinger H, Waltzman RJ, Stalbovskaya V, et al. Results of a randomized study of the JAK inhibitor ruxolitinib (INC424) vs best available therapy (BAT) in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) or post-essential thrombocythemiamyelofibrosis (PET-MF). J Clin Oncol. 2011;29:Abstract LBA6501.
-
(2011)
J Clin Oncol.
, vol.29
-
-
Harrison, C.N.1
Kiladjian, J.2
Al-Ali, H.K.3
Gisslinger, H.4
Waltzman, R.J.5
Stalbovskaya, V.6
-
6
-
-
84868686713
-
RESPONSE: A randomized, open label, phase III study of INC424 in polycythemia vera (PV) in patients resistant to or intolerant of hydroxyurea (HU)
-
Abstract TPS203
-
Verstovsek S, Kiladjian J, Waltzman RJ, Sandor V, Lukawy J, Garrett WM, et al. RESPONSE: a randomized, open label, phase III study of INC424 in polycythemia vera (PV) in patients resistant to or intolerant of hydroxyurea (HU). J Clin Oncol. 2011;29:Abstract TPS203.
-
(2011)
J Clin Oncol.
, vol.29
-
-
Verstovsek, S.1
Kiladjian, J.2
Waltzman, R.J.3
Sandor, V.4
Lukawy, J.5
Garrett, W.M.6
-
7
-
-
80054094068
-
Safety and efficacy of CYT387, a JAK-1/2 inhibitor, for the treatment of myelofibrosis
-
Abstract 6514
-
Pardanani AD, Caramazza D, George G, Lasho TL, Hogan WJ, Litzow MR, et al. Safety and efficacy of CYT387, a JAK-1/2 inhibitor, for the treatment of myelofibrosis. J Clin Oncol. 2011;29:Abstract 6514.
-
(2011)
J Clin Oncol.
, vol.29
-
-
Pardanani, A.D.1
Caramazza, D.2
George, G.3
Lasho, T.L.4
Hogan, W.J.5
Litzow, M.R.6
-
8
-
-
80054098336
-
Phase II study of SB1518, an orally available novel JAK2 inhibitor in patients with myelofibrosis
-
Abstract 6515
-
Deeg HJ, Odenike O, Scott BL, Estrov Z, Cortes JE, Thomas DA, et al. Phase II study of SB1518, an orally available novel JAK2 inhibitor in patients with myelofibrosis. J Clin Oncol. 2011;29:Abstract 6515.
-
(2011)
J Clin Oncol.
, vol.29
-
-
Deeg, H.J.1
Odenike, O.2
Scott, B.L.3
Estrov, Z.4
Cortes, J.E.5
Thomas, D.A.6
-
9
-
-
79952333359
-
Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis
-
Pardanani A, Gotlib JR, Jamieson C, Cortes JE, Talpaz M, Stone RM, et al. Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis. J Clin Oncol. 2011;29:789-96.
-
(2011)
J Clin Oncol.
, vol.29
, pp. 789-796
-
-
Pardanani, A.1
Gotlib, J.R.2
Jamieson, C.3
Cortes, J.E.4
Talpaz, M.5
Stone, R.M.6
-
10
-
-
77949535491
-
Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis
-
Santos FP, Kantarjian HM, Jain N, Manshouri T, Thomas DA, Garcia-Manero G, et al. Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Blood. 2010;115:1131-6.
-
(2010)
Blood.
, vol.115
, pp. 1131-1136
-
-
Santos, F.P.1
Kantarjian, H.M.2
Jain, N.3
Manshouri, T.4
Thomas, D.A.5
Garcia-Manero, G.6
|