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Volumn 17, Issue SUPPL. 1, 2012, Pages

JAK2 inhibitors and their impact in myeloproliferative neoplasms

Author keywords

Acute leukemia; Essential thrombocythemia; JAK2 inhibitor; Myelofibrosis; Myeloproliferative neoplasms; Polycythemia vera; Primary myelofibrosis

Indexed keywords

CYT 387; JANUS KINASE 2 INHIBITOR; LESTAURTINIB; PLACEBO; RUXOLITINIB; SB 1518; TG 101348; UNCLASSIFIED DRUG;

EID: 84859766271     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453312X13336169156375     Document Type: Article
Times cited : (9)

References (10)
  • 1
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couédic JP, Staerk J, Delhommeau F, Lacout C, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-8.
    • (2005) Nature. , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    le Couédic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 2
    • 79952042862 scopus 로고    scopus 로고
    • Targeting myeloproliferative neoplasms with JAK inhibitors
    • Pardanani A, Tefferi A. Targeting myeloproliferative neoplasms with JAK inhibitors. Curr Opin Hematol. 2011;18:105-10.
    • (2011) Curr Opin Hematol. , vol.18 , pp. 105-110
    • Pardanani, A.1    Tefferi, A.2
  • 3
    • 42449124578 scopus 로고    scopus 로고
    • Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
    • Tefferi A, Lasho TL, Huang J, Finke C, Mesa RA, Li CY, et al. Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival. Leukemia. 2008;22:756-61.
    • (2008) Leukemia. , vol.22 , pp. 756-761
    • Tefferi, A.1    Lasho, T.L.2    Huang, J.3    Finke, C.4    Mesa, R.A.5    Li, C.Y.6
  • 5
    • 80051667101 scopus 로고    scopus 로고
    • Results of a randomized study of the JAK inhibitor ruxolitinib (INC424) vs best available therapy (BAT) in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) or post-essential thrombocythemiamyelofibrosis (PET-MF)
    • Abstract LBA6501
    • Harrison CN, Kiladjian J, Al-Ali HK, Gisslinger H, Waltzman RJ, Stalbovskaya V, et al. Results of a randomized study of the JAK inhibitor ruxolitinib (INC424) vs best available therapy (BAT) in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) or post-essential thrombocythemiamyelofibrosis (PET-MF). J Clin Oncol. 2011;29:Abstract LBA6501.
    • (2011) J Clin Oncol. , vol.29
    • Harrison, C.N.1    Kiladjian, J.2    Al-Ali, H.K.3    Gisslinger, H.4    Waltzman, R.J.5    Stalbovskaya, V.6
  • 6
    • 84868686713 scopus 로고    scopus 로고
    • RESPONSE: A randomized, open label, phase III study of INC424 in polycythemia vera (PV) in patients resistant to or intolerant of hydroxyurea (HU)
    • Abstract TPS203
    • Verstovsek S, Kiladjian J, Waltzman RJ, Sandor V, Lukawy J, Garrett WM, et al. RESPONSE: a randomized, open label, phase III study of INC424 in polycythemia vera (PV) in patients resistant to or intolerant of hydroxyurea (HU). J Clin Oncol. 2011;29:Abstract TPS203.
    • (2011) J Clin Oncol. , vol.29
    • Verstovsek, S.1    Kiladjian, J.2    Waltzman, R.J.3    Sandor, V.4    Lukawy, J.5    Garrett, W.M.6
  • 8
    • 80054098336 scopus 로고    scopus 로고
    • Phase II study of SB1518, an orally available novel JAK2 inhibitor in patients with myelofibrosis
    • Abstract 6515
    • Deeg HJ, Odenike O, Scott BL, Estrov Z, Cortes JE, Thomas DA, et al. Phase II study of SB1518, an orally available novel JAK2 inhibitor in patients with myelofibrosis. J Clin Oncol. 2011;29:Abstract 6515.
    • (2011) J Clin Oncol. , vol.29
    • Deeg, H.J.1    Odenike, O.2    Scott, B.L.3    Estrov, Z.4    Cortes, J.E.5    Thomas, D.A.6
  • 10
    • 77949535491 scopus 로고    scopus 로고
    • Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis
    • Santos FP, Kantarjian HM, Jain N, Manshouri T, Thomas DA, Garcia-Manero G, et al. Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Blood. 2010;115:1131-6.
    • (2010) Blood. , vol.115 , pp. 1131-1136
    • Santos, F.P.1    Kantarjian, H.M.2    Jain, N.3    Manshouri, T.4    Thomas, D.A.5    Garcia-Manero, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.