Hydrogen peroxide enhances the expression of G iα proteins in aortic vascular smooth cells: Role of growth factor receptor transactivation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 8, 2012, Pages

  Mbong, Nathan ^a   Anand Srivastava, Madhu B ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Adenylyl cyclase; Extracellular regulated kinase; Hydrogen peroxide; Phosphatidylinositol 3 kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6,7 DIMETHYL 2 PHENYLQUINOXALINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SMALL INTERFERING RNA; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADENYLATE CYCLASE; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, SMOOTH MUSCLE; ONCOGENE PROTEIN V-AKT; OXIDANTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RATS; RECEPTORS, GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84859760333     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00627.2011     Document Type: Article

References (35)

1. Anand-Srivastava MB. Downregulation of atrial natriuretic peptide ANP-C receptor is associated with alterations in G-protein expression in A10 smooth muscle cells. Biochemistry 39: 6503-6513, 2000.
2. Anand-Srivastava MB. Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats. Relationship to adenylate cyclase inhibition. Biochem J 288: 79-85, 1992.
3. Anand-Srivastava MB. Platelets from spontaneously hypertensive rats exhibit decreased expression of inhibitory guanine nucleotide regulatory protein. Relation with adenylyl cyclase activity. Circ Res 73: 1032-1039, 1993.
4. Anand-Srivastava MB, de Champlain J, Thibault C. DOCA-salt hypertensive rat hearts exhibit altered expression of G-proteins. Am J Hypertens 6: 72-75, 1993.
5. Anand-Srivastava MB, Franks DJ, Cantin M, Genest J. Presence of "Ra" and "P"-site receptors for adenosine coupled to adenylate cyclase in cultured vascular smooth muscle cells. Biochem Biophys Res Commun 108: 213-219, 1982.
6. Bray P, Carter A, Simons C, Guo V, Puckett C, Kamholz J, Spiegel A, Nirenberg M. Human cDNA clones for four species of G alpha s signal transduction protein. Proc Natl Acad Sci USA 83: 8893-8897, 1986.
7. Cerione RA, Staniszewski C, Caron MG, Lefkowitz RJ, Codina J, Birnbaumer L. A role for Ni in the hormonal stimulation of adenylate cyclase. Nature 318: 293-295, 1985.
8. Clempus RE, Griendling KK. Reactive oxygen species signaling in vascular smooth muscle cells. Cardiovasc Res 71: 216-225, 2006.
9. Denu JM, Tanner KG. Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry 37: 5633-5642, 1998.
10. di Fusco F, Anand-Srivastava MB. Enhanced expression of Gi proteins in nonhypertrophic hearts from rats with hypertension-induced by L-NAME treatment. J Hypertens 18: 1081-1090, 2000.
11. Feldman AM, Cates AE, Veazey WB, Hershberger RE, Bristow MR, Baughman KL, Baumgartner WA, Van Dop C. Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart. J Clin Invest 82: 189-197, 1988.
12. Frank GD, Eguchi S, Yamakawa T, Tanaka S, Inagami T, Motley ED. Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II. Endocrinology 141: 3120-3126, 2000.
13. Ge C, Garcia R. Anand-Srivastava MB. Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats. Can J Physiol Pharmacol 84: 739-746, 2006.
14. Gilman AG. G proteins: transducers of receptor-generated signals. Annu Rev Biochem 56: 615-649, 1987.
15. Gomez Sandoval YH, Levesque LO, Anand-Srivastava MB. Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells. Can J Physiol Pharmacol 87: 1037-1045, 2009.
16. Hashim S, Liu YY, Wang R, Anand-Srivastava MB. Streptozotocininduced diabetes impairs G-protein linked signal transduction in vascular smooth muscle. Mol Cell Biochem 240: 57-65, 2002.
17. Hayashi S, Morishita R, Matsushita H, Nakagami H, Taniyama Y, Nakamura T, Aoki M, Yamamoto K, Higaki J, Ogihara T. Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21. Hypertension 35: 237-243, 2000.
18. Itoh H, Toyama R, Kozasa T, Tsukamoto T, Matsuoka M, Kaziro Y. Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs. J Biol Chem 263: 6656-6664, 1988.
19. Lappas G, Daou GB, Anand-Srivastava MB. Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats. J Hypertens 23: 2251-2261, 2005.
20. Li Y, Hashim S, Anand-Srivastava MB. Intracellular peptides of natriuretic peptide receptor-C inhibit vascular hypertrophy via Gqalpha/MAP kinase signaling pathways. Cardiovasc Res 72: 464-472, 2006.
21. Li Y, Lappas G, Anand-Srivastava MB. Role of oxidative stress in angiotensin II-induced enhanced expression of Giα proteins and adenylyl cyclase signaling in A10 vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 292: H1922-H1930, 2007.
22. Li Y, Levesque LO, Anand-Srivastava MB. Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR. Am J Physiol Heart Circ Physiol 299: H1959-H1967, 2010.
23. Marcil J, de Champlain J, Anand-Srivastava MB. Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase. Cardiovasc Res 39: 492-505, 1998.
24. Marcil J, Thibault C, Anand-Srivastava MB. Enhanced expression of Gi-protein precedes the development of blood pressure in spontaneously hypertensive rats. J Mol Cell Cardiol 29: 1009-1022, 1997.
25. Mehdi MZ, Azar ZM, Srivastava AK. Role of receptor and nonreceptor protein tyrosine kinases in H2O2-induced PKB and ERK1/2 signaling. Cell Biochem Biophys 47: 1-10, 2007.
26. Pandey SK, Anand-Srivastava MB. Modulation of G-protein expression by the angiotensin converting enzyme inhibitor captopril in hearts from spontaneously hypertensive rats. Relationship with adenylyl cyclase. Am J Hypertens 9: 833-837, 1996.
27. Renshaw MW, Ren XD, Schwartz MA. Growth factor activation of MAP kinase requires cell adhesion. EMBO J 16: 5592-5599, 1997.
28. Rhee SG, Bae YS, Lee SR, Kwon J. Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci STKE 2000: pe1, 2000.
29. Schmidt CM, McKillop IH, Cahill PA, Sitzmann JV. The role of cAMP-MAPK signaling in the regulation of human hepatocellular carcinoma growth in vitro. Eur J Gastroenterol Hepatol 11: 1393-1399, 1999.
30. Schramm M, Selinger Z. Message transmission: receptor controlled adenylate cyclase system. Science 225: 1350-1356, 1984.
31. Tang WJ, Gilman AG. Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits. Science 254: 1500-1503, 1991.
32. Touyz RM, Cruzado M, Tabet F, Yao G, Salomon S, Schiffrin EL. Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation. Can J Physiol Pharmacol 81: 159-167, 2003.
33. Touyz RM, Yao G, Viel E, Amiri F, Schiffrin EL. Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells. J Hypertens 22: 1141-1149, 2004.
34. Wang Y, Yan T, Wang Q, Wang W, Xu J, Wu X, Ji H. PKC-dependent extracellular signal-regulated kinase 1/2 pathway is involved in the inhibition of Ib on AngiotensinII-induced proliferation of vascular smooth muscle cells. Biochem Biophys Res Commun 375: 151-155, 2008.
35. Zafari AM, Ushio-Fukai M, Akers M, Yin Q, Shah A, Harrison DG, Taylor WR, Griendling KK. Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension 32: 488-495, 1998.