Discovery and structural modification of 1-phenyl-3-(1-phenylethyl)urea derivatives as inhibitors of complement

ACS Medicinal Chemistry Letters

Volumn 3, Issue 4, 2012, Pages 317-321

  Zhang, Mei ^a,b   Yang, Xiao Ying ^b   Tang, Wei ^b   Groeneveld, Tom W L ^c   He, Pei Lan ^b   Zhu, Feng Hua ^b   Li, Jia ^b   Lu, Wei ^a   Blom, Anna M ^c   Zuo, Jian Ping ^b   Nan, Fa Jun ^b  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c LUND UNIVERSITY   (Sweden)

Author keywords

C9; complement inhibitors; high throughput screening; structural modification

Indexed keywords

1 PHENYL 3 (1 PHENYLETHYL)UREA DERIVATIVE; COMPLEMENT INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH THROUGHPUT SCREENING; IC 50; PRIORITY JOURNAL;

EID: 84859754252     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300005w     Document Type: Article

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