The cytotoxicity of polycationic iron oxide nanoparticles: Common endpoint assays and alternative approaches for improved understanding of cellular response mechanism

Journal of Nanobiotechnology

Volumn 10, Issue , 2012, Pages

  Hoskins, Clare ^a   Cuschieri, Alfred ^a   Wang, Lijun ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Atomic force microscopy; Cell membrane; Cell viability assay; Cellular interaction; Cytotoxicity; Magnetic nanoparticle; Zeta potential

Indexed keywords

ACIDIC ENVIRONMENT; AFM; ALTERNATIVE APPROACH; BIOMEDICAL APPLICATIONS; CELL LINES; CELL MORPHOLOGY; CELL VIABILITY; CELLULAR ASSAYS; CELLULAR INTERACTION; CELLULAR RESPONSE; CELLULAR STATE; COMPLETE INFORMATION; CYTOSKELETONS; CYTOTOXIC EFFECTS; FTIR; IN-DEPTH STUDY; IN-VITRO; IRON OXIDE NANOPARTICLE; LIPID PEROXIDATION; MAGNETIC NANOPARTICLES; MCF-7 CELLS; MEMBRANE DISRUPTION; MEMBRANE INTEGRITY; NEUTRAL PH; PARTICLE SYNTHESIS; POLYETHYLENIMINES; POSITIVE CHARGES; REACTIVE OXYGEN SPECIES; RELATIVE UTILITY; SODIUM CITRATE; TOPOGRAPHY IMAGES; TOPOGRAPHY IMAGING; U937 CELL;

ASSAYS; ATOMIC FORCE MICROSCOPY; CELL CULTURE; CELL MEMBRANES; COATINGS; IRON OXIDES; MEDICAL APPLICATIONS; NANOPARTICLES; POLYETHYLENE GLYCOLS; SODIUM; TOPOGRAPHY; ZETA POTENTIAL;

CYTOTOXICITY;

IRON OXIDE; LACTATE DEHYDROGENASE; MACROGOL; MAGNETIC NANOPARTICLE; NANOCOATING; POLY(ETHYLENIMINE); REACTIVE OXYGEN METABOLITE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; FERRIC ION; FERRIC OXIDE; MACROGOL DERIVATIVE; MAGNETITE NANOPARTICLE; POLY(ETHYLENE GLYCOL) CO POLY(ETHYLENEIMINE); POLY(ETHYLENE GLYCOL)-CO-POLY(ETHYLENEIMINE); POLYETHYLENEIMINE;

ARTICLE; CELL ASSAY; CELL INTERACTION; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; CYTOTOXICITY TEST; ELECTRICITY; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MEMBRANE STRUCTURE; MOLECULAR STABILITY; PH; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; CELL LINE; CELL MEMBRANE; CELL STRAIN U937; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; METABOLISM; ULTRASTRUCTURE;

CELL LINE; CELL MEMBRANE; CELL SURVIVAL; FERRIC COMPOUNDS; HUMANS; LIPID PEROXIDATION; MAGNETITE NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; REACTIVE OXYGEN SPECIES; U937 CELLS;

EID: 84859753577     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/1477-3155-10-15     Document Type: Article

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