Individual differences in nucleus accumbens activity to food and sexual images predict weight gain and sexual behavior

Journal of Neuroscience

Volumn 32, Issue 16, 2012, Pages 5549-5552

  Demos, Kathryn E ^a,b   Heatherton, Todd F ^a   Kelley, William M ^a  

^a Dartmouth College   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; APPETITE; ARTICLE; ASSOCIATION; BODY MASS; FEMALE; FOLLOW UP; FOOD; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; INDIVIDUALITY; NORMAL HUMAN; NUCLEUS ACCUMBENS; OVERNUTRITION; PREDICTION; PRIORITY JOURNAL; REWARD; SEXUAL BEHAVIOR; VISUAL STIMULATION; WEIGHT GAIN;

ADOLESCENT; CUES; FEMALE; FOLLOW-UP STUDIES; FOOD; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGINATION; INDIVIDUALITY; MAGNETIC RESONANCE IMAGING; MALE; MOTIVATION; NUCLEUS ACCUMBENS; OXYGEN; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; REWARD; SEXUAL BEHAVIOR; WEIGHT GAIN; YOUNG ADULT;

EID: 84859738471     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5958-11.2012     Document Type: Article

References (30)

1. Arnsten AF (2009) Stress signaling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 10:410-422.
2. Back SE, Hartwell K, DeSantis SM, Saladin M, McRae-Clark AL, Price KL, Moran-Santa Maria MM, Baker NL, Spratt E, Kreek MJ, Brady KT (2010) Reactivity to laboratory stress provocation predicts relapse to cocaine. Drug Alcohol Depend 106:21-27.
3. Bargh JA, Morsella E (2008) The unconscious mind. Perspect Psychol Sci 3:73-79.
4. Brooks SJ, O'Daly OG, Uher R, Friederich HC, Giampietro V, Brammer M, Williams SC, Schiöth HB, Treasure J, Campbell IC (2011) Differential neural responses to food images in women with bulimia versus anorexia nervosa. PLoS One 6:e22259.
5. Cloutier J, Heatherton TF, Whalen PJ, Kelley WM (2008) Are attractive people rewarding? Sex differences in the neural substrates of facial attractiveness. J Cogn Neurosci 20:941-951.
6. Demos KE, Kelley WM, Heatherton TF (2011) Dietary restraint violations influence reward responses in nucleus accumbens and amygdala. J Cogn Neurosci 23:1952-1963.
7. Dijksterhuis A, Chartrand TL, Aarts H (2007) Effects of priming and perception on social behavior and goal pursuit. In: Social psychology and the unconscious: the automaticity of higher mental processes (Bargh JA, ed), pp 51-132. Philadelphia: Psychology
8. Drummond DC, Cooper T, Glautier SP (1990) Conditioned learning in alcohol dependence: implications for cue exposure treatment. Br J Addict 85:725-743.
9. Friston KJ, Holmes AP, Worsley KJ, Poline JB, Frith CD, Frackowiak RS (1995) Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 2:189-210.
10. Hamann S, Herman RA, Nolan CL, Wallen K (2004) Men and women differ in amygdala response to visual sexual stimuli. Nat Neurosci 7:411-416.
11. Hare TA, Camerer CF, Rangel A (2009) Self-control in decision-making involves modulation of the vmPFC valuation system. Science 324:646-648.
12. Heatherton TF (2011) Neuroscience of self and self-regulation. Annu Rev Psychol 62:363-390.
13. Heatherton TF, Baumeister RF (1991) Binge eating as escape from selfawareness. Psychol Bull 110:86-108.
14. Heatherton TF, Wagner DD (2011) Cognitive neuroscience of selfregulation failure. Trends Cogn Sci 15:132-139.
15. Janes AC, Pizzagalli DA, Richardt S, deB Frederick B, Chuzi S, Pachas G, Culhane MA, Holmes AJ, Fava M, Evins AE, Kaufman MJ (2010) Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol Psychiatry 67:722-729.
16. Jansen A (1998) A learning model of binge eating: cue reactivity and cue exposure. Behav Res Ther 36:257-272.
17. Kober H, Mende-Siedlecki P, Kross EF, Weber J, Mischel W, Hart CL, Ochsner KN (2010) Prefrontal-striatal pathway underlies cognitive regulation of craving. Proc Natl Acad Sci U S A 107:14811-14816.
18. Lang PJ, Bradley MM, Cuthbert BN (2008) International affective picture system (IAPS): affective ratings of pictures and instruction manual. Technical Report A-8. Gainesville, FL: University of Florida.
19. Martin LN, Delgado MR (2011) The influence of emotion regulation on decision making under risk. J Cogn Neurosci 23:2569-2581.
20. Neto LL, Oliveira E, Correia F, Ferreira AG (2008) The human nucleus accumbens: where is it? A stereotactic, anatomical and magnetic resonance imaging study. Neuromodulation 11:13-22.
21. Passamonti L, Rowe JB, Schwarzbauer C, Ewbank MP, von dem Hagen E, Calder AJ (2009) Personality predicts the brain's response to viewing appetizing foods: the neural basis of a risk factor for overeating. J Neurosci 29:43-51.
22. Piazza PV, Le MoalM (1998) The role of stress in drug self-administration. Trends Pharmacol Sci 19:67-74.
23. Simpson JA, Gangestad SW (1991) Individual differences in sociosexuality: evidence for convergent and discriminant validity. J Pers Soc Psychol 60:870-883.
24. Spector IP, Carey MP, Steinberg L (1996) The sexual desire inventory: development, factor structure, and evidence of reliability. J Sex Marital Ther 22:175-190.
25. Stacy AW, Wiers RW (2010) Implicit cognition and addiction: a tool for explaining paradoxical behavior. Annu Rev Clin Psychol 6:551-575.
26. Staudinger MR, Erk S, Walter H (2011) Dorsolateral prefrontal cortex modulates striatal reward encoding during reappraisal of reward anticipation. Cereb Cortex 21:2578-2588.
27. Stewart J, de Wit H, Eikelboom R (1984) Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants. Psychol Rev 91:251-268.
28. Stice E, Yokum S, Bohon C, Marti N, Smolen A (2010) Reward circuitry responsivity to food predicts future increases in body mass: moderating effects of DRD2 and DRD4. Neuroimage 50:1618-1625.
29. Stoeckel LE, Weller RE, Cook EW 3rd, Twieg DB, Knowlton RC, Cox JE (2008) Widespread reward-system activation in obese women in response to pictures of high-calorie foods. Neuroimage 41:636-647.
30. Wagner DD, Dal Cin S, Sargent JD, Kelley WM, Heatherton TF (2011) Spontaneous action representation in smokers when watching movie characters smoke. J Neurosci 31:894-898.