Hepatitis B virus X gene in the development of hepatocellular carcinoma

Hong Kong Medical Journal

Volumn 17, Issue 6 SUPPL 6, 2011, Pages 44-47

  Ma, N F ^a   Lau, S H ^a   Hu, L ^a   Dong, S S ^a   Guan, X Y ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; COMPLEMENTARY DNA; TRANSACTIVATOR PROTEIN; VIRUS DNA;

APOPTOSIS; ARTICLE; CANCER RISK; CARBOXY TERMINAL SEQUENCE; CARCINOGENICITY; CELL PROLIFERATION; DNA MICROARRAY; GENE DELETION; GENE EXPRESSION; GENETIC RISK; HEPATITIS B VIRUS; HEPATITIS B VIRUS X GENE; HUMAN; LIVER CELL CARCINOMA; NONHUMAN; PROTEIN EXPRESSION; RISK FACTOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; HEPG2 CELL LINE; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER CANCER CELL LINE; MIHA CELL LINE; MOUSE; PATHOGENESIS; POLYMERASE CHAIN REACTION; TUMOR XENOGRAFT; TUNEL ASSAY; ANIMAL; CELL STRAIN HEPG2; DRUG SCREENING; GENETICS; HEPATITIS B; LIVER TUMOR; NUDE MOUSE; TUMOR CELL LINE; VIROLOGY;

ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DNA, VIRAL; HEP G2 CELLS; HEPATITIS B; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANS-ACTIVATORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84859715833     PISSN: 10242708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002;31:339-46.
2. Wang Y, Lau SH, Sham JS, Wu MC, Wang T, Guan XY. Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis. Oncogene 2004;23:142-8.
3. Tu H, Bonura C, Giannini C, et al. Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues. Cancer Res 2001;61:7803-10.