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Volumn 42, Issue 5, 2012, Pages 526-533

Aliskiren reduces portal pressure in portal hypertensive rats

Author keywords

Aliskiren; Nitric oxide; Portal hypertension; Porto systemic collaterals

Indexed keywords

ALISKIREN; ARGININE; CREATININE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; VASOPRESSIN;

EID: 84859706022     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2011.02611.x     Document Type: Article
Times cited : (8)

References (31)
  • 3
    • 25444454353 scopus 로고    scopus 로고
    • A human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
    • Pilz B, Shagdarsuren E, Wellner M, Fiebeler A, Dechend R, Gratze P et al. A human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension 2005;46:569-76.
    • (2005) Hypertension , vol.46 , pp. 569-576
    • Pilz, B.1    Shagdarsuren, E.2    Wellner, M.3    Fiebeler, A.4    Dechend, R.5    Gratze, P.6
  • 4
    • 57449084151 scopus 로고    scopus 로고
    • Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure
    • Westermann D, Riad A, Lettau O, Roks A, Savvatis K, Becher PM et al. Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure. Hypertension 2008;52:1068-75.
    • (2008) Hypertension , vol.52 , pp. 1068-1075
    • Westermann, D.1    Riad, A.2    Lettau, O.3    Roks, A.4    Savvatis, K.5    Becher, P.M.6
  • 5
    • 46449118638 scopus 로고    scopus 로고
    • Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
    • Feldman DL, Jin L, Xuan H, Contrepas A, Zhou Y, Webb RL et al. Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 2008;52:130-6.
    • (2008) Hypertension , vol.52 , pp. 130-136
    • Feldman, D.L.1    Jin, L.2    Xuan, H.3    Contrepas, A.4    Zhou, Y.5    Webb, R.L.6
  • 6
    • 52049097072 scopus 로고    scopus 로고
    • Renin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changes
    • Imanishi T, Tsujioka H, Ikejima H, Kuroi A, Takarada S, Kitabata H et al. Renin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changes. Hypertension 2008;52:563-72.
    • (2008) Hypertension , vol.52 , pp. 563-572
    • Imanishi, T.1    Tsujioka, H.2    Ikejima, H.3    Kuroi, A.4    Takarada, S.5    Kitabata, H.6
  • 7
    • 50349094508 scopus 로고    scopus 로고
    • Aliskiren
    • Brown MJ. Aliskiren. Circulation 2008;118:773-84.
    • (2008) Circulation , vol.118 , pp. 773-784
    • Brown, M.J.1
  • 8
    • 42649109044 scopus 로고    scopus 로고
    • Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents
    • Nguyen G, Danser AH. Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents. Exp Physiol 2008;93:557-63.
    • (2008) Exp Physiol , vol.93 , pp. 557-563
    • Nguyen, G.1    Danser, A.H.2
  • 9
    • 27444447364 scopus 로고    scopus 로고
    • Renin, prorenin and the putative (pro)renin receptor
    • Danser AH, Deinum J. Renin, prorenin and the putative (pro)renin receptor. Hypertension 2005;46:1069-76.
    • (2005) Hypertension , vol.46 , pp. 1069-1076
    • Danser, A.H.1    Deinum, J.2
  • 11
    • 0034849461 scopus 로고    scopus 로고
    • Cellular and molecular basis of portal hypertension
    • Shah V. Cellular and molecular basis of portal hypertension. Clin Liver Dis 2001;5:629-44.
    • (2001) Clin Liver Dis , vol.5 , pp. 629-644
    • Shah, V.1
  • 13
    • 0020677377 scopus 로고
    • Hyperdynamic circulation in portal-hypertensive rat model: a primary factor for maintenance of chronic portal hypertension
    • Vorobioff J, Bredfeldt JE, Groszmann RJ. Hyperdynamic circulation in portal-hypertensive rat model: a primary factor for maintenance of chronic portal hypertension. Am J Physiol 1983;244:G52-7.
    • (1983) Am J Physiol , vol.244
    • Vorobioff, J.1    Bredfeldt, J.E.2    Groszmann, R.J.3
  • 14
    • 0034998782 scopus 로고    scopus 로고
    • In vivo angiogenesis in normal and portal hypertensive rats: role of basic fibroblast growth factor and nitric oxide
    • Sieber CC, Sumanovski LT, Stumm M, van der Kooij M, Battegay E. In vivo angiogenesis in normal and portal hypertensive rats: role of basic fibroblast growth factor and nitric oxide. J Hepatol 2001;34:644-50.
    • (2001) J Hepatol , vol.34 , pp. 644-650
    • Sieber, C.C.1    Sumanovski, L.T.2    Stumm, M.3    van der Kooij, M.4    Battegay, E.5
  • 15
    • 0032858372 scopus 로고    scopus 로고
    • Effects of vasopressin on portal-systemic collaterals in portal hypertensive rats: role of nitric oxide and prostaglandin
    • Chan CC, Lee FY, Wang SS, Chang FY, Lin HC, Chu CJ et al. Effects of vasopressin on portal-systemic collaterals in portal hypertensive rats: role of nitric oxide and prostaglandin. Hepatology 1999;30:630-5.
    • (1999) Hepatology , vol.30 , pp. 630-635
    • Chan, C.C.1    Lee, F.Y.2    Wang, S.S.3    Chang, F.Y.4    Lin, H.C.5    Chu, C.J.6
  • 16
    • 0019522762 scopus 로고
    • Measurement of the portal-systemic shunting in the rat by using γ-labeled microspheres
    • Chojkier M, Groszmann RJ. Measurement of the portal-systemic shunting in the rat by using γ-labeled microspheres. Am J Physiol 1981;240:G371-5.
    • (1981) Am J Physiol , vol.240
    • Chojkier, M.1    Groszmann, R.J.2
  • 18
    • 0025966706 scopus 로고
    • Influence of anesthesia, postanesthetic state, and restraint on superior mesenteric arterial flow in normal rats
    • Colombato LA, Sabbà C, Polio J, Groszmann RJ. Influence of anesthesia, postanesthetic state, and restraint on superior mesenteric arterial flow in normal rats. Am J Physiol 1991;260:G1-5.
    • (1991) Am J Physiol , vol.260
    • Colombato, L.A.1    Sabbà, C.2    Polio, J.3    Groszmann, R.J.4
  • 19
    • 45549093442 scopus 로고    scopus 로고
    • Review article: the modern management of portal hypertension - primary and secondary prophylaxis of variceal bleeding in cirrhotic patients
    • Garcia-Pagan JC, De Gottardi A, Bosch J. Review article: the modern management of portal hypertension - primary and secondary prophylaxis of variceal bleeding in cirrhotic patients. Aliment Pharmacol Ther 2008;28:178-86.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 178-186
    • Garcia-Pagan, J.C.1    De Gottardi, A.2    Bosch, J.3
  • 21
    • 0036731212 scopus 로고    scopus 로고
    • Primary prophylaxis of variceal hemorrhage: a randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate
    • Lui HF, Stanley AJ, Forrest EH, Jalan R, Hislop WS, Mills PR et al. Primary prophylaxis of variceal hemorrhage: a randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate. Gastroenterology 2002;123:735-44.
    • (2002) Gastroenterology , vol.123 , pp. 735-744
    • Lui, H.F.1    Stanley, A.J.2    Forrest, E.H.3    Jalan, R.4    Hislop, W.S.5    Mills, P.R.6
  • 22
    • 0034922565 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibitors and angiotensin II antagonists as therapy in chronic liver disease
    • Vlachogiannakos J, Tang AK, Patch D, Burroughs AK. Angiotensin converting enzyme inhibitors and angiotensin II antagonists as therapy in chronic liver disease. Gut 2001;49:303-8.
    • (2001) Gut , vol.49 , pp. 303-308
    • Vlachogiannakos, J.1    Tang, A.K.2    Patch, D.3    Burroughs, A.K.4
  • 24
    • 75149139972 scopus 로고    scopus 로고
    • Effect of direct renin inhibition on renal hemodynamic function, arterial stiffness, and endothelial function in humans with uncomplicated type 1 diabetes: a pilot study
    • Cherney DZ, Lai V, Scholey JW, Miller JA, Zinman B, Reich HN. Effect of direct renin inhibition on renal hemodynamic function, arterial stiffness, and endothelial function in humans with uncomplicated type 1 diabetes: a pilot study. Diabetes Care 2010;33:361-5.
    • (2010) Diabetes Care , vol.33 , pp. 361-365
    • Cherney, D.Z.1    Lai, V.2    Scholey, J.W.3    Miller, J.A.4    Zinman, B.5    Reich, H.N.6
  • 25
    • 0019383360 scopus 로고
    • Effect of angiotensin-II blockade on systemic and hepatic haemodynamics and on the renin-angiotensin-aldosterone system in cirrhosis with ascites
    • Arroyo V, Bosch J, Mauri M, Ribera F, Navarro-Lopez F, Rodes J. Effect of angiotensin-II blockade on systemic and hepatic haemodynamics and on the renin-angiotensin-aldosterone system in cirrhosis with ascites. Eur J Clin Invest 1981;11:221-9.
    • (1981) Eur J Clin Invest , vol.11 , pp. 221-229
    • Arroyo, V.1    Bosch, J.2    Mauri, M.3    Ribera, F.4    Navarro-Lopez, F.5    Rodes, J.6
  • 26
    • 0034898990 scopus 로고    scopus 로고
    • Hemodynamic effects of the angiotensin II receptor antagonist irbesartan in patients with cirrhosis and portal hypertension
    • Schepke M, Werner E, Biecker E, Schiedermaier P, Heller J, Neef M et al. Hemodynamic effects of the angiotensin II receptor antagonist irbesartan in patients with cirrhosis and portal hypertension. Gastroenterology 2001;121:389-95.
    • (2001) Gastroenterology , vol.121 , pp. 389-395
    • Schepke, M.1    Werner, E.2    Biecker, E.3    Schiedermaier, P.4    Heller, J.5    Neef, M.6
  • 28
    • 14044271546 scopus 로고    scopus 로고
    • Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats
    • Wood JM, Schnell CR, Cumin F, Menard J, Webb RL. Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats. J Hypertens 2005;23:417-26.
    • (2005) J Hypertens , vol.23 , pp. 417-426
    • Wood, J.M.1    Schnell, C.R.2    Cumin, F.3    Menard, J.4    Webb, R.L.5
  • 29
    • 70349251477 scopus 로고    scopus 로고
    • Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice
    • Yamamoto E, Kataoka K, Dong YF, Nakamura T, Fukuda M, Tokutomi Y et al. Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice. Hypertension 2009;54:633-8.
    • (2009) Hypertension , vol.54 , pp. 633-638
    • Yamamoto, E.1    Kataoka, K.2    Dong, Y.F.3    Nakamura, T.4    Fukuda, M.5    Tokutomi, Y.6
  • 30
    • 77949713481 scopus 로고    scopus 로고
    • Aliskiren ameliorates chlorhexidine digluconate-induced peritoneal fibrosis in rats
    • Ke CY, Lee CC, Lee CJ, Subeq YM, Lee RP, Hsu BG. Aliskiren ameliorates chlorhexidine digluconate-induced peritoneal fibrosis in rats. Eur J Clin Invest 2010;40:301-9.
    • (2010) Eur J Clin Invest , vol.40 , pp. 301-309
    • Ke, C.Y.1    Lee, C.C.2    Lee, C.J.3    Subeq, Y.M.4    Lee, R.P.5    Hsu, B.G.6
  • 31
    • 42949109643 scopus 로고    scopus 로고
    • Aliskiren: the first renin inhibitor for clinical treatment
    • Jensen C, Herold P, Brunner HR. Aliskiren: the first renin inhibitor for clinical treatment. Nat Rev Drug Discov 2008;7:399-410.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 399-410
    • Jensen, C.1    Herold, P.2    Brunner, H.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.