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Volumn 46, Issue 4, 2012, Pages 590-598

Dapagliflozin for the treatment of type 2 diabetes;Dapagliflozina para el tratamiento de la diabetes tipo 2

Author keywords

Dapagliflozin; SGLT2 inhibitor; Sodium glucose cotransporter 2 inhibitor; Type 2 diabetes mellitus

Indexed keywords

DAPAGLIFLOZIN; GLIMEPIRIDE; GLIPIZIDE; GLUCOSE; HEMOGLOBIN A1C; METFORMIN; PIOGLITAZONE; PLACEBO; SITAGLIPTIN;

EID: 84859705044     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1Q538     Document Type: Review
Times cited : (35)

References (24)
  • 1
    • 84859700253 scopus 로고    scopus 로고
    • WebMD Diabetes Health Center. (accessed 2011 Nov 14)
    • WebMD Diabetes Health Center. World diabetes: 366 million cases and counting. http://diabetes.webmd.com/news/20110914/world-diabetes-366-million-cases-and-counting (accessed 2011 Nov 14).
    • World diabetes: 366 million cases and counting
  • 2
    • 79960614571 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. (accessed 2011 Nov 14)
    • National diabetes fact sheet, 2011. Centers for Disease Control and Prevention. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf (accessed 2011 Nov 14).
    • (2011) National diabetes fact sheet
  • 4
    • 0028963260 scopus 로고
    • Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years
    • United Kingdom Prospective Diabetes Study (UKPDS)
    • United Kingdom Prospective Diabetes Study (UKPDS). Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years. BMJ 1995;310:83-8.
    • (1995) BMJ , vol.310 , pp. 83-88
  • 5
    • 0028817815 scopus 로고
    • Overview of 6 years' therapy of type II diabetes: A progressive disease
    • UK Prospective Diabetes Study 16, UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. UK Prospective Diabetes Study (UKPDS) Group. Diabetes 1995;44:1249-58.
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 7
    • 0344440817 scopus 로고
    • Renal glucose transport
    • In: Seldin DW, Giebisch G, eds. 2nd ed. New York: Raven Press, Ltd
    • Deetjen P, von Baeyer H, Drexel H. Renal glucose transport. In: Seldin DW, Giebisch G, eds. The kidney: physiology and pathophysiology. 2nd ed. New York: Raven Press, Ltd., 1992:2873-88.
    • (1992) The kidney: Physiology and pathophysiology , pp. 2873-2888
    • Deetjen, P.1    von Baeyer, H.2    Drexel, H.3
  • 9
    • 1242272759 scopus 로고    scopus 로고
    • The sodium/glucose cotransport family SLC5
    • Wright EM, Turk E. The sodium/glucose cotransport family SLC5. Eur J Physiol 2004;447:510-8.
    • (2004) Eur J Physiol , vol.447 , pp. 510-518
    • Wright, E.M.1    Turk, E.2
  • 10
    • 0036937335 scopus 로고    scopus 로고
    • Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2)
    • van den Heuvel LP, Assink K, Willemsen M, Monnens L. Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2). Hum Genet 2002;111:544-7.
    • (2002) Hum Genet , vol.111 , pp. 544-547
    • van den Heuvel, L.P.1    Assink, K.2    Willemsen, M.3    Monnens, L.4
  • 11
    • 84899135333 scopus 로고    scopus 로고
    • Bristol-Myers Squibb Company, AstraZeneca. Bristol-Myers Squibb, AstraZeneca July 13, (accessed 2011 Nov 14)
    • Bristol-Myers Squibb Company, AstraZeneca. NDA 202293 Dapagliflozin: Endocrinologic & Metabolic Advisory Committee background document. Bristol-Myers Squibb, AstraZeneca July 13, 2011. http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeeting Materials/Drugs/EndocrinologicandMetabolicDrugsAdvisoryCommittee/ UCM262996.pdf (accessed 2011 Nov 14).
    • (2011) NDA 202293 Dapagliflozin: Endocrinologic & Metabolic Advisory Committee background document
  • 12
    • 82855162710 scopus 로고    scopus 로고
    • Influence of hepatic impairment on the pharmacokinetics and safety profile of dapagliflozin: An open-label, parallel-group, single-dose study
    • Kasichayanula S, Liu X, Zhang W, Pfister M, LaCreta FP, Boulton DW. Influence of hepatic impairment on the pharmacokinetics and safety profile of dapagliflozin: an open-label, parallel-group, single-dose study. Clin Ther 2011;33:1798-808.
    • (2011) Clin Ther , vol.33 , pp. 1798-1808
    • Kasichayanula, S.1    Liu, X.2    Zhang, W.3    Pfister, M.4    la Creta, F.P.5    Boulton, D.W.6
  • 13
    • 79951897566 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus
    • Kasichayanula S, Chang M, Hasegawa M, et al. Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus. Diabetes Obes Metab 2011;13:357-65.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 357-365
    • Kasichayanula, S.1    Chang, M.2    Hasegawa, M.3
  • 14
    • 67349180574 scopus 로고    scopus 로고
    • Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects
    • Komoroski B, Vachharajani N, Boulton D, et al. Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther 2009;85:520-6.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 520-526
    • Komoroski, B.1    Vachharajani, N.2    Boulton, D.3
  • 15
    • 78649715079 scopus 로고    scopus 로고
    • Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects
    • Kasichayanula S, Liu X, Shyu WC, et al. Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects. Diabetes Obes Metab 2011;13:47-54.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 47-54
    • Kasichayanula, S.1    Liu, X.2    Shyu, W.C.3
  • 16
    • 67349275999 scopus 로고    scopus 로고
    • Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes
    • Komoroski B, Vachharajani N, Feng Y, Li L, Kornhauser D, Pfister M. Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes. Clin Pharmacol Ther 2009;85:513-9.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 513-519
    • Komoroski, B.1    Vachharajani, N.2    Feng, Y.3    Li, L.4    Kornhauser, D.5    Pfister, M.6
  • 17
    • 65349196064 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care 2009;32:650-7.
    • (2009) Diabetes Care , vol.32 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3    Tang, W.4    Fiedorek, F.T.5
  • 18
    • 69549095914 scopus 로고    scopus 로고
    • A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus sensitizers: Applicability of a novel insulin-dependent treatment
    • Wilding JPH, Norwood P, T'joen C, Bastien A, List JF, Fiedorek FT. A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus sensitizers: applicability of a novel insulin-dependent treatment. Diabetes Care 2009;32:1656-62.
    • (2009) Diabetes Care , vol.32 , pp. 1656-1662
    • Wilding, J.P.H.1    Norwood, P.2    T'joen, C.3    Bastien, A.4    List, J.F.5    Fiedorek, F.T.6
  • 19
    • 77956921439 scopus 로고    scopus 로고
    • Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise
    • Ferrannini E, Ramos SJ, Salsali A, Tang W, List JF. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise. Diabetes Care 2010;33:2217-24.
    • (2010) Diabetes Care , vol.33 , pp. 2217-2224
    • Ferrannini, E.1    Ramos, S.J.2    Salsali, A.3    Tang, W.4    List, J.F.5
  • 20
    • 33744600902 scopus 로고    scopus 로고
    • (accessed 2011 Nov 14)
    • National Institutes of Health. ClinicalTrials. gov. http://clinicaltrials.gov/ ct2/results?term=dapagliflozin+monotherapy (accessed 2011 Nov 14).
    • National Institutes of Health
  • 21
    • 80155124676 scopus 로고    scopus 로고
    • Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: A randomized, 52-week, double-blind, active-controlled noninferiority trial
    • Aug 4. (Epub ahead of print)
    • Nauck MA, Del Prato S, Meier JJ, et al. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial. Diabetes Care 2011 Aug 4. (Epub ahead of print).
    • (2011) Diabetes Care
    • Nauck, M.A.1    del Prato, S.2    Meier, J.J.3
  • 22
    • 77953857048 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
    • Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet 2010;375:2223-33.
    • (2010) Lancet , vol.375 , pp. 2223-2233
    • Bailey, C.J.1    Gross, J.L.2    Pieters, A.3    Bastien, A.4    List, J.F.5
  • 23
    • 80052524011 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: A randomised, 24-week, doubleblind, placebo-controlled trial
    • Strojek K, Yoon KH, Hruba V, Elze M, Langkide AM, Parikh S. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomised, 24-week, doubleblind, placebo-controlled trial. Diabetes Obes Metab 2011;13:928-38.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 928-938
    • Strojek, K.1    Yoon, K.H.2    Hruba, V.3    Elze, M.4    Langkide, A.M.5    Parikh, S.6
  • 24
    • 76749111151 scopus 로고    scopus 로고
    • In vitro characterization and pharmacokinetics of dapagliflozin (BMS-512148), a potent sodium-glucose cotransporter type II inhibitor, in animals and humans
    • Obermeier M, Yao M, Khanna A, et al. In vitro characterization and pharmacokinetics of dapagliflozin (BMS-512148), a potent sodium-glucose cotransporter type II inhibitor, in animals and humans. Drug Metab Dispos 2010;38:405-14.
    • (2010) Drug Metab Dispos , vol.38 , pp. 405-414
    • Obermeier, M.1    Yao, M.2    Khanna, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.