메뉴 건너뛰기




Volumn 25, Issue 2, 2012, Pages 107-115

Cellularity and cartilage matrix increased in hypertrophied ligamentum flavum: Histopathological analysis focusing on the mechanical stress and bone morphogenetic protein signaling

Author keywords

bone morphogenetic protein; cartilage matrix formation; degenerative lumbar canal stenosis; ligamentum flavum; mechanical stress

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; ENDOGLIN; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR SOX9;

EID: 84859651978     PISSN: 15360652     EISSN: 15392465     Source Type: Journal    
DOI: 10.1097/BSD.0b013e31820bb76e     Document Type: Article
Times cited : (24)

References (29)
  • 2
    • 39049089534 scopus 로고    scopus 로고
    • Pathomechanism of loss of elasticity and hypertrophy of lumbar ligamentum flavum in elderly patients with lumbar spinal canal stenosis
    • DOI 10.1097/BRS.0b013e31815b650f, PII 0000763220071201000005
    • Kosaka H, Sairyo K, Biyani A, et al. Pathomechanism of loss of elasticity and hypertrophy of lumbar ligamentum flavum in elderly patients with lumbar spinal canal stenosis. Spine. 2007;32:2805-2811. (Pubitemid 351339349)
    • (2007) Spine , vol.32 , Issue.25 , pp. 2805-2811
    • Kosaka, H.1    Sairyo, K.2    Biyani, A.3    Leaman, D.4    Yeasting, R.5    Higashino, K.6    Sakai, T.7    Katoh, S.8    Sano, T.9    Goel, V.K.10    Yasui, N.11
  • 3
    • 3542998653 scopus 로고    scopus 로고
    • The pathology of ligamentum flavum in degenerative lumbar disease
    • Okuda T, Baba I, Fujimoto Y, et al. The pathology of ligamentum flavum in degenerative lumbar disease. Spine (Philadelphia, PA 1976). 2004;29:1689-1697.
    • (2004) Spine (Philadelphia, PA 1976) , vol.29 , pp. 1689-1697
    • Okuda, T.1    Baba, I.2    Fujimoto, Y.3
  • 4
    • 0032796374 scopus 로고    scopus 로고
    • Histology of the ligamentum flavum in patients with degenerative lumbar spinal stenosis
    • DOI 10.1007/s005860050181
    • Schrader PK, Grob D, Rahn BA, et al. Histology of the ligamentum flavum in patients with degenerative lumbar spinal stenosis. Eur Spine J. 1999;8:323-328. (Pubitemid 29390136)
    • (1999) European Spine Journal , vol.8 , Issue.4 , pp. 323-328
    • Schrader, P.K.1    Grob, D.2    Rahn, B.A.3    Cordey, J.4    Dvorak, J.5
  • 5
    • 0026442263 scopus 로고
    • Hypertrophied ligamentum flavum in lumbar spinal canal stenosis. Pathogenesis and morphologic and immunohistochemical observation
    • Yoshida M, Shima K, Taniguchi Y, et al. Hypertrophied ligamentum flavum in lumbar spinal canal stenosis. Pathogenesis and morphologic and immunohistochemical observation. Spine. 1992;17:1353-1360.
    • (1992) Spine , vol.17 , pp. 1353-1360
    • Yoshida, M.1    Shima, K.2    Taniguchi, Y.3
  • 6
    • 0028909352 scopus 로고
    • The effect of mechanical stress on hypertrophy of the lumbar ligamentum flavum
    • Fukuyama S, Nakamura T, Ikeda T, et al. The effect of mechanical stress on hypertrophy of the lumbar ligamentum flavum. J Spinal Disord. 1995;8:126-130.
    • (1995) J Spinal Disord , vol.8 , pp. 126-130
    • Fukuyama, S.1    Nakamura, T.2    Ikeda, T.3
  • 7
    • 0036436022 scopus 로고    scopus 로고
    • Mechanical stretching force promotes collagen synthesis by cultured cells from human ligamentum flavum via transforming growth factor-beta1
    • DOI 10.1016/S0736-0266(02)00046-3, PII S0736026602000463
    • Nakatani T, Marui T, Hitora T, et al. Mechanical stretching force promotes collagen synthesis by cultured cells from human ligamentum flavum via transforming growth factor-beta1. J Orthop Res. 2002;20:1380-1386. (Pubitemid 35364000)
    • (2002) Journal of Orthopaedic Research , vol.20 , Issue.6 , pp. 1380-1386
    • Nakatani, T.1    Marui, T.2    Hitora, T.3    Doita, M.4    Nishida, K.5    Kurosaka, M.6
  • 8
    • 18044403830 scopus 로고    scopus 로고
    • Quantitative analysis of transforming growth factor-beta 1 in ligamentum flavum of lumbar spinal stenosis and disc herniation
    • Park JB, Chang H, Lee JK. Quantitative analysis of transforming growth factor-beta 1 in ligamentum flavum of lumbar spinal stenosis and disc herniation. Spine. 2001;26:E492-E495.
    • (2001) Spine , vol.26
    • Park, J.B.1    Chang, H.2    Lee, J.K.3
  • 9
    • 28844508615 scopus 로고    scopus 로고
    • Pathomechanism of ligamentum flavum hypertrophy: A multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments
    • DOI 10.1097/01.brs.0000188117.77657.ee
    • Sairyo K, Biyani A, Goel V, et al. Pathomechanism of ligamentum flavum hypertrophy: a multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments. Spine. 2005;30:2649-2656. (Pubitemid 41780375)
    • (2005) Spine , vol.30 , Issue.23 , pp. 2649-2656
    • Sairyo, K.1    Biyani, A.2    Goel, V.3    Leaman, D.4    Booth Jr., R.5    Thomas, J.6    Gehling, D.7    Vishnubhotla, S.L.8    Long, R.9    Ebraheim, N.10
  • 10
    • 0034021776 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
    • Gilboa L, Nohe A, Geissendorfer T, et al. Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell. 2000;11:1023-1035. (Pubitemid 30159319)
    • (2000) Molecular Biology of the Cell , vol.11 , Issue.3 , pp. 1023-1035
    • Gilboa, L.1    Nohe, A.2    Geissendorfer, T.3    Sebald, W.4    Henis, Y.I.5    Knaus, P.6
  • 11
    • 0002071012 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: From basic science to clinical applications
    • Reddi AH. Bone morphogenetic proteins: from basic science to clinical applications. J Bone Joint Surg Am. 2001;83-A(suppl 1):S1-S6.
    • (2001) J Bone Joint Surg Am , vol.83 A , Issue.SUPPL. 1
    • Reddi, A.H.1
  • 12
    • 0030955344 scopus 로고    scopus 로고
    • Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage
    • Zou H, Wieser R, Massague J, et al. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev. 1997;11:2191-2203. (Pubitemid 27387970)
    • (1997) Genes and Development , vol.11 , Issue.17 , pp. 2191-2203
    • Zou, H.1    Wieser, R.2    Massague, J.3    Niswander, L.4
  • 14
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • DOI 10.1038/nature02006
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature. 2003;425:577-584. (Pubitemid 37280136)
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 18
    • 0032100625 scopus 로고    scopus 로고
    • Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats
    • DOI 10.1016/S8756-3282(98)00056-8, PII S8756328298000568
    • Onishi T, Ishidou Y, Nagamine T, et al. Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats. Bone. 1998;22:605-612. (Pubitemid 28284608)
    • (1998) Bone , vol.22 , Issue.6 , pp. 605-612
    • Onishi, T.1    Ishidou, Y.2    Nagamine, T.3    Yone, K.4    Imamura, T.5    Kato, M.6    Sampath, T.K.7    Ten, D.P.T.8    Sakou, T.9
  • 19
    • 0033565488 scopus 로고    scopus 로고
    • Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc
    • DOI 10.1097/00007632-199907150-00002
    • Takae R, Matsunaga S, Origuchi N, et al. Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc. Spine. 1999;24:1397-1401. (Pubitemid 29331410)
    • (1999) Spine , vol.24 , Issue.14 , pp. 1397-1401
    • Takae, R.1    Matsunaga, S.2    Origuchi, N.3    Yamamoto, T.4    Morimoto, N.5    Suzuki, S.6    Sakou, T.7
  • 21
    • 4043089297 scopus 로고    scopus 로고
    • Lumbar instability and clinical symptoms: Which is the more critical factor for symptoms: Sagittal translation or segment angulation?
    • Iguchi T, Kanemura A, Kasahara K, et al. Lumbar instability and clinical symptoms: which is the more critical factor for symptoms: sagittal translation or segment angulation? J Spinal Disord Tech. 2004;17:284-290.
    • (2004) J Spinal Disord Tech , vol.17 , pp. 284-290
    • Iguchi, T.1    Kanemura, A.2    Kasahara, K.3
  • 22
    • 16244422690 scopus 로고    scopus 로고
    • Cyclic hydrostatic compression stimulates chondroinduction of C3H/10T1/2 cells
    • DOI 10.1007/s10237-004-0058-3
    • Elder SH, Fulzele KS, McCulley WR. Cyclic hydrostatic compression stimulates chondroinduction of C3H/10T1/2 cells. Biomech Model Mechanobiol. 2005;3:141-146. (Pubitemid 40454313)
    • (2005) Biomechanics and Modeling in Mechanobiology , vol.3 , Issue.3 , pp. 141-146
    • Elder, S.H.1    Fulzele, K.S.2    McCulley, W.R.3
  • 23
    • 2942553906 scopus 로고    scopus 로고
    • Effects of cyclic compressive loading on chondrogenesis of rabbit bone-marrow derived mesenchymal stem cells
    • Huang CY, Hagar KL, Frost LE, et al. Effects of cyclic compressive loading on chondrogenesis of rabbit bone-marrow derived mesenchymal stem cells. Stem Cells. 2004;22:313-323. (Pubitemid 38736615)
    • (2004) Stem Cells , vol.22 , Issue.3 , pp. 313-323
    • Huang, C.-Y.C.1    Hagar, K.L.2    Frost, L.E.3    Sun, Y.4    Cheung, H.S.5
  • 24
    • 66249107073 scopus 로고    scopus 로고
    • Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer
    • Steinert AF, Palmer GD, Pilapil C, et al. Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Eng Part A. 2009;15:1127-1139.
    • (2009) Tissue Eng Part A , vol.15 , pp. 1127-1139
    • Steinert, A.F.1    Palmer, G.D.2    Pilapil, C.3
  • 26
    • 0030823929 scopus 로고    scopus 로고
    • Fibroblasts of spinal ligaments pathologically differentiate into chondrocytes induced by recombinant human bone morphogenetic protein-2: Morphological examinations for ossification of spinal ligaments
    • DOI 10.1016/S8756-3282(97)00106-3, PII S8756328297001063
    • Hoshi K, Amizuka N, Sakou T, et al. Fibroblasts of spinal ligaments pathologically differentiate into chondrocytes induced by recombinant human bone morphogenetic protein-2: morphological examinations for ossification of spinal ligaments. Bone. 1997;21:155-162. (Pubitemid 27395403)
    • (1997) Bone , vol.21 , Issue.2 , pp. 155-162
    • Hoshi, K.1    Amizuka, N.2    Sakou, T.3    Kurokawa, T.4    Ozawa, H.5
  • 27
    • 0346252654 scopus 로고    scopus 로고
    • Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault
    • DOI 10.1242/dev.00793
    • Ishii M, Merrill AE, Chan YS, et al. Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault. Development. 2003;130:6131-6142. (Pubitemid 38016176)
    • (2003) Development , vol.130 , Issue.24 , pp. 6131-6142
    • Ishii, M.1    Merrill, A.E.2    Chan, Y.-S.3    Gitelman, I.4    Rice, D.P.C.5    Sucov, H.M.6    Maxson Jr., R.E.7
  • 29
    • 56349169536 scopus 로고    scopus 로고
    • Mechanotransduction-a field pulling together?
    • Chen CS. Mechanotransduction-a field pulling together? J Cell Sci. 2008;121:3285-3292.
    • (2008) J Cell Sci , vol.121 , pp. 3285-3292
    • Chen, C.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.