-
2
-
-
45949099964
-
From Darwin's finches to canaries in the coal mine - Mining the genome for new biology
-
Hunter DJ, Altshuler D, Rader DJ. From Darwin's finches to canaries in the coal mine - mining the genome for new biology. N Engl J Med. 2008;358:2796-2803.
-
(2008)
N Engl J Med
, vol.358
, pp. 2796-2803
-
-
Hunter, D.J.1
Altshuler, D.2
Rader, D.J.3
-
3
-
-
77949578084
-
Performance of common genetic variants in breast-cancer risk models
-
Wacholder S, Hartge P, Prentice R, et al. Performance of common genetic variants in breast-cancer risk models. N Engl J Med. 2010;363:2272.
-
(2010)
N Engl J Med
, vol.363
, pp. 2272
-
-
Wacholder, S.1
Hartge, P.2
Prentice, R.3
-
4
-
-
33846563409
-
Why most published research findings are false
-
Ioannidis JP. Why most published research findings are false. PLoS Med. 2005;2:e124.
-
(2005)
PLoS Med
, vol.2
-
-
Ioannidis, J.P.1
-
5
-
-
80051552041
-
The false-positive to false-negative ratio in epidemiologic studies
-
Ioannidis JP, Tarone R, McLaughlin JK. The false-positive to false-negative ratio in epidemiologic studies. Epidemiology. 2011;22:450-456.
-
(2011)
Epidemiology
, vol.22
, pp. 450-456
-
-
Ioannidis, J.P.1
Tarone, R.2
McLaughlin, J.K.3
-
6
-
-
0017042882
-
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design
-
Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I: Introduction and design. Br J Cancer. 1976;34:585-612. (Pubitemid 8004970)
-
(1976)
British Journal of Cancer
, vol.34
, Issue.6
, pp. 585-612
-
-
Peto, R.1
Pike, M.C.2
Armitage, P.3
-
7
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango AH, Estrada K, Lettre G, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010;467:832-838.
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango, A.H.1
Estrada, K.2
Lettre, G.3
-
8
-
-
33745608452
-
Methods for pooling results of epidemiologic studies: The pooling project of prospective studies of diet and cancer
-
DOI 10.1093/aje/kwj127
-
Smith-Warner SA, Spiegelman D, Ritz J, et al. Methods for pooling results of epidemiologic studies: the pooling project of prospective studies of diet and cancer. Am J Epidemiol. 2006;163:1053-1064. (Pubitemid 43987598)
-
(2006)
American Journal of Epidemiology
, vol.163
, Issue.11
, pp. 1053-1064
-
-
Smith-Warner, S.A.1
Spiegelman, D.2
Ritz, J.3
Albanes, D.4
Beeson, W.L.5
Bernstein, L.6
Berrino, F.7
Van Den, B.P.A.8
Buring, J.E.9
Cho, E.10
Colditz, G.A.11
Folsom, A.R.12
Freudenheim, J.L.13
Giovannucci, E.14
Goldbohm, R.A.15
Graham, S.16
Harnack, L.17
Horn-Ross, P.L.18
Krogh, V.19
Leitzmann, M.F.20
McCullough, M.L.21
Miller, A.B.22
Rodriguez, C.23
Rohan, T.E.24
Schatzkin, A.25
Shore, R.26
Virtanen, M.27
Willett, W.C.28
Wolk, A.29
Zeleniuch-Jacquotte, A.30
Zhang, S.M.31
Hunter, D.J.32
more..
-
9
-
-
0030843969
-
Breast cancer and hormone replacement therapy: Collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer
-
Collaborative Group on Hormonal Factors in Breast Cancer
-
Collaborative Group on Hormonal Factors in Breast Cancer.Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Lancet. 1997;350:1047-1059.
-
(1997)
Lancet
, vol.350
, pp. 1047-1059
-
-
-
10
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls. Nature. 2007;447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
11
-
-
32144461525
-
Cohort profile: 1958 British birth cohort (National Child Development Study)
-
DOI 10.1093/ije/dyi183
-
Power C, Elliott J. Cohort profile: 1958 British birth cohort (National Child Development Study). Int J Epidemiol. 2006;35:34-41. (Pubitemid 43205440)
-
(2006)
International Journal of Epidemiology
, vol.35
, Issue.1
, pp. 34-41
-
-
Power, C.1
Elliott, J.2
-
12
-
-
34547510624
-
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
-
DOI 10.1038/ng2062, PII NG2062
-
Gudmundsson J, Sulem P, Steinthorsdottir V, et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet. 2007;39:977-983. (Pubitemid 47185170)
-
(2007)
Nature Genetics
, vol.39
, Issue.8
, pp. 977-983
-
-
Gudmundsson, J.1
Sulem, P.2
Steinthorsdottir, V.3
Bergthorsson, J.T.4
Thorleifsson, G.5
Manolescu, A.6
Rafnar, T.7
Gudbjartsson, D.8
Agnarsson, B.A.9
Baker, A.10
Sigurdsson, A.11
Benediktsdottir, K.R.12
Jakobsdottir, M.13
Blondal, T.14
Stacey, S.N.15
Helgason, A.16
Gunnarsdottir, S.17
Olafsdottir, A.18
Kristinsson, K.T.19
Birgisdottir, B.20
Ghosh, S.21
Thorlacius, S.22
Magnusdottir, D.23
Stefansdottir, G.24
Kristjansson, K.25
Bagger, Y.26
Wilensky, R.L.27
Reilly, M.P.28
Morris, A.D.29
Kimber, C.H.30
Adeyemo, A.31
Chen, Y.32
Zhou, J.33
So, W.-Y.34
Tong, P.C.Y.35
Ng, M.C.Y.36
Hansen, T.37
Andersen, G.38
Borch-Johnsen, K.39
Jorgensen, T.40
Tres, A.41
Fuertes, F.42
Ruiz-Echarri, M.43
Asin, L.44
Saez, B.45
Van Boven, E.46
Klaver, S.47
Swinkels, D.W.48
Aben, K.K.49
Graif, T.50
Cashy, J.51
Suarez, B.K.52
Van Vierssen, T.O.53
Frigge, M.L.54
Ober, C.55
Hofker, M.H.56
Wijmenga, C.57
Christiansen, C.58
Rader, D.J.59
Palmer, C.N.A.60
Rotimi, C.61
Chan, J.C.N.62
Pedersen, O.63
Sigurdsson, G.64
Benediktsson, R.65
Jonsson, E.66
Einarsson, G.V.67
Mayordomo, J.I.68
Catalona, W.J.69
Kiemeney, L.A.70
Barkardottir, R.B.71
Gulcher, J.R.72
Thorsteinsdottir, U.73
Kong, A.74
Stefansson, K.75
more..
-
13
-
-
0028345626
-
Implications of measurement error in exposure for the sample sizes of case-control studies
-
McKeown-Eyssen GE, Tibshirani R. Implications of measurement error in exposure for the sample sizes of case-control studies. Am J Epidemiol. 1994;139:415-421. (Pubitemid 24081341)
-
(1994)
American Journal of Epidemiology
, vol.139
, Issue.4
, pp. 415-421
-
-
McKeown-Eyssen, G.E.1
Tibshirani, R.2
-
14
-
-
27644546712
-
Population structure, differential bias and genomic control in a large-scale, case-control association study
-
DOI 10.1038/ng1653, PII N1653
-
Clayton DG, Walker NM, Smyth DJ, et al. Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat Genet. 2005;37:1243-1246. (Pubitemid 41568707)
-
(2005)
Nature Genetics
, vol.37
, Issue.11
, pp. 1243-1246
-
-
Clayton, D.G.1
Walker, N.M.2
Smyth, D.J.3
Pask, R.4
Cooper, J.D.5
Maier, L.M.6
Smink, L.J.7
Lam, A.C.8
Ovington, N.R.9
Stevens, H.E.10
Nutland, S.11
Howson, J.M.M.12
Faham, M.13
Moorhead, M.14
Jones, H.B.15
Falkowski, M.16
Hardenbol, P.17
Willis, T.D.18
Todd, J.A.19
-
15
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander ES, Schork NJ. Genetic dissection of complex traits. Science. 1994;265:2037-2048. (Pubitemid 24325685)
-
(1994)
Science
, vol.265
, Issue.5181
, pp. 2037-2048
-
-
Lander, E.S.1
Schork, N.J.2
-
16
-
-
0034686618
-
Population stratification in epidemiologic studies of common genetic variants and cancer: Quantification of bias
-
Wacholder S, Rothman N, Caporaso N. Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias. J Natl Cancer Inst. 2000;92:1151-1158.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1151-1158
-
-
Wacholder, S.1
Rothman, N.2
Caporaso, N.3
-
17
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
DOI 10.1038/ng1847, PII NG1847
-
Price AL, Patterson NJ, Plenge RM, et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38:904-909. (Pubitemid 44141658)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
18
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Science USA. 2009;106:9362-9367.
-
(2009)
Proc Natl Acad Science USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
-
19
-
-
0036517472
-
A comprehensive review of genetic association studies
-
DOI 10.1097/00125817-200203000-00002
-
Hirschhorn JN, Lohmueller K, Byrne E, et al. A comprehensive review of genetic association studies. Genet Med. 2002;4:45-61. (Pubitemid 44698579)
-
(2002)
Genetics in Medicine
, vol.4
, Issue.2
, pp. 45-61
-
-
Hirschhorn, J.N.1
Lohmueller, K.2
Byrne, E.3
Hirschhorn, K.4
-
20
-
-
79951703690
-
Comprehensive analysis of hormone and genetic variation in 36 genes related to steroid hormone metabolism in pre- and postmenopausal women from the breast and prostate cancer cohort consortium (BPC3)
-
Beckmann L, Husing A, Setiawan VW, et al. Comprehensive analysis of hormone and genetic variation in 36 genes related to steroid hormone metabolism in pre- and postmenopausal women from the breast and prostate cancer cohort consortium (BPC3). J Clin Endocrinol Metab. 2011;96:E360-E367.
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Beckmann, L.1
Husing, A.2
Setiawan, V.W.3
-
21
-
-
77956594771
-
Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium
-
Canzian F, Cox DG, Setiawan VW, et al. Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. Hum Mol Genet. 2010;19:3873-3884.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3873-3884
-
-
Canzian, F.1
Cox, D.G.2
Setiawan, V.W.3
-
22
-
-
0026195734
-
Multiple comparisons? No Problem!
-
Poole C. Multiple comparisons? No Problem! Epidemiology. 1991;2:241-243.
-
(1991)
Epidemiology
, vol.2
, pp. 241-243
-
-
Poole, C.1
-
23
-
-
0025893282
-
Empirical-Bayes adjustments for multiple comparisons are sometimes useful
-
Greenland S, Robins JM. Empirical-Bayes adjustments for multiple comparisons are sometimes useful. Epidemiology. 1991;2:244-251.
-
(1991)
Epidemiology
, vol.2
, pp. 244-251
-
-
Greenland, S.1
Robins, J.M.2
-
24
-
-
0025031812
-
No adjustments are needed for multiple comparisons
-
Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology. 1990;1:43-46. (Pubitemid 20255621)
-
(1990)
Epidemiology
, vol.1
, Issue.1
, pp. 43-46
-
-
Rothman, K.J.1
-
25
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature. 2009;461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
26
-
-
79952489475
-
Estimating missing heritability for disease from genome-wide association studies
-
Lee SH, Wray NR, Goddard ME, et al. Estimating missing heritability for disease from genome-wide association studies. Am J Hum Genet. 2011;88:294-305.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 294-305
-
-
Lee, S.H.1
Wray, N.R.2
Goddard, M.E.3
-
27
-
-
79960943621
-
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
-
Sanna S, Li B, Mulas A, et al. Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet. 2011;7:e1002198.
-
(2011)
PLoS Genet
, vol.7
-
-
Sanna, S.1
Li, B.2
Mulas, A.3
|