Effects of variable blast pressures on blood flow and oxygen saturation in rat brain as evidenced using MRI

Magnetic Resonance Imaging

Volumn 30, Issue 4, 2012, Pages 527-534

  Bir, Cynthia ^a   VandeVord, Pamela ^a,b   Shen, Yimin ^b   Raza, Waqar ^b   Haacke, E Mark ^a,b  

^a Wayne State University   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

Blast; MRI; Neurotrauma; Rat model

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY CORTEX; BLOOD OXYGENATION; BRAIN BLOOD FLOW; CONTROLLED STUDY; EXPOSURE; HIPPOCAMPUS; HYPERBARISM; IMAGE ANALYSIS; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PRIORITY JOURNAL; RAT; SHOCK; THALAMUS; TUBE;

ANIMALS; BLAST INJURIES; BRAIN INJURIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; SPIN LABELS;

ANIMALIA; RATTUS;

EID: 84859642788     PISSN: 0730725X     EISSN: 18735894     Source Type: Journal    
DOI: 10.1016/j.mri.2011.12.003     Document Type: Article

References (16)

1. Gondusky J.S., Reiter M.P. Protecting military convoys in Iraq: an examination of battle injuries sustained by mechanized battalion during Operation Iraqi Freedom II. Mil Med 2005, 170:546-549.
2. Okie S. Traumatic brain injury in the war zone. N Engl J Med 2005, 352(20):2043-2047.
3. Zoroya G. Key Iraq wound: brain trauma. USA Today 2005.
4. Cernak I., Wang Z., Jiang J., Bian X., Savic J. Cognitive deficits following blast injury-induced neurotrauma: possible involvement of nitric oxide. Brain Inj 2001, 15(7):593-612.
5. Elder G.A., Cristian A. Blast-related mild traumatic brain injury: mechanisms of injury and impact on clinical care. Mt Sinai J Med 2009, 76(2):111-118.
6. Avila M., Sell S.L., Kadoi Y., Prough D.S., Hellmich H.L., Velasco M., et al. l-Arginine decreases fluid-percussion injury-induced neuronal nitrotyrosine immunoreactivity in rats. J Cereb Blood Flow Metab 2008, 28:1733-1741.
7. DeWitt D.S., Prough D.S. Blast-induced brain injury and posttraumatic hypotension and hypoxemia. J Neurotrauma 2009, 26(6):877-887.
8. Shen Y., Kou Z., Kreipke C.W., Petrov T., Hu J., Haacke E.M. In vivo measurement of tissue damage, oxygen saturation changes and blood flow changes after experimental traumatic brain injury in rats using susceptibility weighted imaging. Magn Reson Imaging 2007, 25:219-227.
9. Reichenbach J.R., Venkatesan R., Schillinger D.J., Kido D.K., Haacke E.M. Small vessels in the human brain: MR venography with deoxyhemoglobin as an intrinsic contrast agent. Radiology 1997, 204:272-277.
10. Tong K.A., Ashwal S., Holshouser B.A., Shutter L.A., Herigault G., Haacke E.M., et al. Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology 2003, 227(2):332-339.
11. Wycliffe N.D., Choe J., Holshouser B., Oyoyo U.E., Haacke E.M., Kido D.K. Reliability in detection of hemorrhage in acute stroke by a new three-dimensional gradient recalled echo susceptibility-weighted imaging technique compared to computed tomography: a retrospective study. J Magn Reson Imaging 2004, 20(3):372-377.
12. Sigmund G.A., Tong K.A., Nickerson J.P., Wall C.J., Oyoyo U., Ashwal S. Multimodality comparison of neuroimaging in pediatric traumatic brain injury. Pediatr Neurol 2007, 36(4):217-226.
13. Chastain C.A., Oyoyo U., Zipperman M., Joo E., Ashwal S., Shutter L., et al. Predicting outcomes of traumatic brain injury by imaging modality and injury distribution. J Neurotrauma 2009, 26(8):1183-1196.
14. Detre J.A., Leigh J.S., Williams D.S., Koretsky A.P. Perfusion imaging. Magn Reson Med 1992, 23:37-45.
15. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 2005, Elsevier Academic Press, San Diego. 5th ed.
16. Haacke E.M., Filleti C.L., Gattu R., Ciulla C., Al-Bashir A., Suryanarayanan K., et al. New algorithm for quantifying vascular changes in dynamic contrast-enhanced MRI independent of absolute T1 values. Magn Reson Med 2007, 58:463-472.