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This article shows the reasons and results of reclassification and initiation of active treatment in the PRIAS consortium over 6 years
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Bul M, van den Bergh RC, Rannikko A, et al. Predictors of unfavourable repeat biopsy results in men participating in a prospective active surveillance program. Eur Urol 2011. This article shows the reasons and results of reclassification and initiation of active treatment in the PRIAS consortium over 6 years.
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Klotz L, Zhang L, Lam A, et al. Clinical results of long-termfollow-up of a large, active surveillance cohort with localized prostate cancer. J Clin Oncol 2010; 28:126-131. This article shows the results of surveillance and treatment in the Canadian cohort that has the longest median follow-up in the world.
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Tosoian JJ, Trock BJ, Landis P, et al. Active surveillance program for prostate cancer: an update of the Johns Hopkins experience. J Clin Oncol 2011; 29:2185-2190. This article shows the results of active surveillance and treatment based on a protocol that uses only biopsies to reclassify patient risk on progressive disease.
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This article shows the results of active surveillance in a cohort that is based on very strict inclusion criteria of one positive biopsy only
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Soloway MS, Soloway CT, Eldefrawy A, et al. Careful selection and close monitoring of low-risk prostate cancer patients on active surveillance minimizes the need for treatment. Eur Urol 2010; 58:831-835. This article shows the results of active surveillance in a cohort that is based on very strict inclusion criteria of one positive biopsy only.
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This article illustrates that the role of MRI for selection of cancer patients for active surveillance might well be overestimated currently, and that prospective monitoring studies are needed
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Ploussard G, Xylinas E, Durand X, et al. Magnetic resonance imaging does not improve the prediction of misclassification of prostate cancer patients eligible for active surveillance when the most stringent selection criteria are based on the saturation biopsy scheme. BJU Int 2010. This article illustrates that the role of MRI for selection of cancer patients for active surveillance might well be overestimated currently, and that prospective monitoring studies are needed.
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BJU Int
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Ploussard, G.1
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This article shows that molecular markers may play a role in the inclusion of patients for active surveillance, but that prospective studies are needed
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Wolters T, Vissers KJ, Bangma CH, et al. The value of EZH2, p27(kip1), BMI-1 and MIB-1 on biopsy specimens with low-risk prostate cancer in selecting men with significant prostate cancer at prostatectomy. BJU Int 2010; 106:280-286. This article shows that molecular markers may play a role in the inclusion of patients for active surveillance, but that prospective studies are needed.
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Selecting men diagnosed with prostate cancer for active surveillance using a risk calculator: A prospective impact study
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van Vugt HA, Roobol MJ, van der Poel HG, et al. Selecting men diagnosed with prostate cancer for active surveillance using a risk calculator: a prospective impact study. BJU Int 2011. This article shows that the compliance of physicians and patients to risk assessment tools stratifying patients for active surveillance are well accepted and followed in 82% of cases.
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BJU Int
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