Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Kan o, Meikun ^a   Takeya, Ryu ^a   Taniguchi, Kenichiro ^a   Tanoue, Yoshihisa ^a   Tominaga, Ryuji ^a   Sumimoto, Hideki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FHOD3 PROTEIN; FORMIN PROTEIN; ISOPROTEIN; MESSENGER RNA; MYOSIN; PROTEIN; UNCLASSIFIED DRUG; ACTIN; ACTIN BINDING PROTEIN; FHOD3 PROTEIN, MOUSE;

ACTIN FILAMENT; ADULT ANIMAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CROSS LINKING; CYTOSKELETON; EMBRYO; EXON; GENE EXPRESSION; HEART; HEART CELL CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MAMMAL; MOUSE; MOUSE EMBRYO; MYOSIN FILAMENT; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SARCOMERE; THIN FILAMENT; ADULT; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART MUSCLE CELL; METABOLISM; TRANSGENIC MOUSE;

MAMMALIA; MUS;

ACTIN CYTOSKELETON; ACTINS; ADULT; ANIMALS; CELLS, CULTURED; EXONS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MYOCYTES, CARDIAC; PROTEIN ISOFORMS; SARCOMERES;

EID: 84859611356     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034765     Document Type: Article

References (19)

1. Clark KA, McElhinny AS, Beckerle MC, Gregorio CC, (2002) Striated muscle cytoarchitecture: An intricate web of form and function. Annu Rev Cell Dev Biol 18: 637-706.
2. Littlefield RS, Fowler VM, (2008) Thin filament length regulation in striated muscle sarcomeres: Pointed-end dynamics go beyond a nebulin ruler. Semin Cell Dev Biol 19: 511-519.
3. Sparrow JC, Schöck F, (2009) The initial steps of myofibril assembly: Integrins pave the way. Nat Rev Mol Cell Biol 10: 293-298.
4. Sanger JW, Wang J, Fan Y, White J, Sanger JM, (2010) Assembly and dynamics of myofibrils. J Biomed Biotechnol 2010: 858606.
5. Ono S, (2010) Dynamic regulation of sarcomeric actin filaments in striated muscle. Cytoskeleton (Hoboken) 67: 677-692.
6. Chereau D, Boczkowska M, Skwarek-Maruszewska A, Fujiwara I, Hayes DB, et al. (2008) Leiomodin is an actin filament nucleator in muscle cells. Science 320: 239-243.
7. Takano K, Watanabe-Takano H, Suetsugu S, Kurita S, Tsujita K, et al. (2010) Nebulin and N-WASP cooperate to cause IGF-1-induced sarcomeric actin filament formation. Science 330: 1536-1540.
8. Chesarone MA, DuPage AG, Goode BL, (2010) Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol 11: 62-74.
9. Campellone KG, Welch MD, (2010) A nucleator arms race: Cellular control of actin assembly. Nat Rev Mol Cell Biol 11: 237-251.
10. Taniguchi K, Takeya R, Suetsugu S, Kan-o M, Narusawa M, et al. (2009) Mammalian formin Fhod3 regulates actin assembly and sarcomere organization in striated muscles. J Biol Chem 284: 29873-29881.
11. Kanaya H, Takeya R, Takeuchi K, Watanabe N, Jing N, et al. (2005) Fhos2, a novel formin-related actin-organizing protein, probably associates with the nestin intermediate filament. Genes Cells 10: 665-678.
12. Iskratsch T, Lange S, Dwyer J, Kho AL, dos Remedios C, et al. (2010) Formin follows function: A muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance. J Cell Biol 191: 1159-1172.
13. Sanger JW, Mittal B, Sanger JM, (1984) Formation of myofibrils in spreading chick cardiac myocytes. Cell Motil 4: 405-416.
14. Bai J, Hartwig JH, Perrimon N, (2007) SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during drosophila muscle growth. Dev Cell 13: 828-842.
15. Mizushima S, Nagata S, (1990) pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res 18: 5322.
16. Gulick J, Subramaniam A, Neumann J, Robbins J, (1991) Isolation and characterization of the mouse cardiac myosin heavy chain genes. J Biol Chem 266: 9180-9185.
17. Kulandavelu S, Qu D, Sunn N, Mu J, Rennie MY, et al. (2006) Embryonic and neonatal phenotyping of genetically engineered mice. ILAR J 47: 103-117.
18. Goshima K, (1973) A study on the preservation of the beating rhythm of single myocardial cells in vitro. Exp Cell Res 80: 432-438.
19. Tokuyasu KT, (1986) Application of cryoultramicrotomy to immunocytochemistry. J Microsc 143: 139-149.