메뉴 건너뛰기




Volumn 88, Issue 5, 2012, Pages 446-449

The potential benefits of participating in early-phase clinical trials in multiple myeloma: Long-term remission in a patient with relapsed multiple myeloma treated with 90 cycles of lenalidomide and bortezomib

Author keywords

Bortezomib; Lenalidomide; Long term treatment; Multiple myeloma; Relapse

Indexed keywords

BORTEZOMIB; DEXAMETHASONE; LENALIDOMIDE; PAMIDRONIC ACID; THALIDOMIDE;

EID: 84859602910     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2012.01765.x     Document Type: Article
Times cited : (9)

References (18)
  • 1
    • 36349023319 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma
    • Dimopoulos M, Spencer A, Attal M, et al. Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med 2007;357:2123-32.
    • (2007) N Engl J Med , vol.357 , pp. 2123-2132
    • Dimopoulos, M.1    Spencer, A.2    Attal, M.3
  • 2
    • 36349010285 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America
    • Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America. N Engl J Med 2007;357:2133-42.
    • (2007) N Engl J Med , vol.357 , pp. 2133-2142
    • Weber, D.M.1    Chen, C.2    Niesvizky, R.3
  • 3
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003;348:2609-17.
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 4
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Richardson PG, Sonneveld P, Schuster MW, et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005;352:2487-98.
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3
  • 5
    • 35148825003 scopus 로고    scopus 로고
    • Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial
    • Richardson PG, Sonneveld P, Schuster M, et al. Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial. Blood 2007;110:3557-60.
    • (2007) Blood , vol.110 , pp. 3557-3560
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.3
  • 6
    • 0034331194 scopus 로고    scopus 로고
    • Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
    • Hideshima T, Chauhan D, Shima Y, et al. Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood 2000;96:2943-50.
    • (2000) Blood , vol.96 , pp. 2943-2950
    • Hideshima, T.1    Chauhan, D.2    Shima, Y.3
  • 7
    • 0037097595 scopus 로고    scopus 로고
    • Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
    • Mitsiades N, Mitsiades CS, Poulaki V, et al. Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood 2002;99:4525-30.
    • (2002) Blood , vol.99 , pp. 4525-4530
    • Mitsiades, N.1    Mitsiades, C.S.2    Poulaki, V.3
  • 8
    • 73349115580 scopus 로고    scopus 로고
    • Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma
    • Richardson PG, Weller E, Jagannath S, et al. Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma. J Clin Oncol 2009;27:5713-9.
    • (2009) J Clin Oncol , vol.27 , pp. 5713-5719
    • Richardson, P.G.1    Weller, E.2    Jagannath, S.3
  • 9
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 2010;116:679-86.
    • (2010) Blood , vol.116 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3
  • 10
    • 84859609127 scopus 로고    scopus 로고
    • Bortezomib (Velcade)-thalidomide-dexamethasone is superior to thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation
    • Presented at the 37th Annual Meeting of the European Group for Blood and Marrow Transplantation, Paris, France. 4 April 2011
    • Garderet L, Iacobelli S, Moreau P, et al. Bortezomib (Velcade)-thalidomide-dexamethasone is superior to thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation. Presented at the 37th Annual Meeting of the European Group for Blood and Marrow Transplantation, Paris, France. 4 April 2011.
    • Garderet, L.1    Iacobelli, S.2    Moreau, P.3
  • 11
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • San Miguel JF, Schlag R, Khuageva N, et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008;359:906-17.
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.3
  • 12
    • 73249146496 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial
    • Rajkumar SV, Jacobus S, Callander NS, et al. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol 2010;11:29-37.
    • (2010) Lancet Oncol , vol.11 , pp. 29-37
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.S.3
  • 13
    • 79551615800 scopus 로고    scopus 로고
    • The immunostimulatory effect of lenalidomide on NK-cell function is profoundly inhibited by concurrent dexamethasone therapy
    • Hsu AK, Quach H, Tai T, et al. The immunostimulatory effect of lenalidomide on NK-cell function is profoundly inhibited by concurrent dexamethasone therapy. Blood 2011;117:1605-13.
    • (2011) Blood , vol.117 , pp. 1605-1613
    • Hsu, A.K.1    Quach, H.2    Tai, T.3
  • 14
    • 78650303638 scopus 로고    scopus 로고
    • Phase III intergroup study of lenalidomide versus placebo maintenance therapy following single autologous stem cell transplant (ASCT) for multiple myeloma (MM): CALGB 100104
    • Abstract 8017
    • McCarthy PL, Owzar K, Anderson KC, et al. Phase III intergroup study of lenalidomide versus placebo maintenance therapy following single autologous stem cell transplant (ASCT) for multiple myeloma (MM): CALGB 100104. J Clin Oncol 2010;28(15 Suppl):Abstract 8017.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • McCarthy, P.L.1    Owzar, K.2    Anderson, K.C.3
  • 15
    • 78650333538 scopus 로고    scopus 로고
    • Lenalidomide maintenance after transplantation for myeloma
    • Abstract 8018
    • Attal M, Cristini C, Marit G, et al. Lenalidomide maintenance after transplantation for myeloma. J Clin Oncol 2010;28(15 Suppl):Abstract 8018.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Attal, M.1    Cristini, C.2    Marit, G.3
  • 16
    • 77954660886 scopus 로고    scopus 로고
    • Bortezomib, dexamethasone, cyclophosphamide and lenalidomide in newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study
    • Kumar SK, Flinn I, Noga SJ, et al. Bortezomib, dexamethasone, cyclophosphamide and lenalidomide in newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study. Leukemia 2010;24:1350-6.
    • (2010) Leukemia , vol.24 , pp. 1350-1356
    • Kumar, S.K.1    Flinn, I.2    Noga, S.J.3
  • 17
    • 79951797822 scopus 로고    scopus 로고
    • Novel three- and four-drug combination regimens of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide, for previously untreated multiple myeloma: results from the multi-center, randomized, phase 2 EVOLUTION study
    • Abstract 621
    • Kumar S, Flinn IW, Richardson PG, et al. Novel three- and four-drug combination regimens of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide, for previously untreated multiple myeloma: results from the multi-center, randomized, phase 2 EVOLUTION study. Blood 2010;116:Abstract 621.
    • (2010) Blood , vol.116
    • Kumar, S.1    Flinn, I.W.2    Richardson, P.G.3
  • 18
    • 79960666079 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Consortium trial
    • Jakubowiak AJ, Griffith KA, Reece DE, et al. Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Consortium trial. Blood 2011;118:535-43.
    • (2011) Blood , vol.118 , pp. 535-543
    • Jakubowiak, A.J.1    Griffith, K.A.2    Reece, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.