메뉴 건너뛰기




Volumn 728, Issue , 2012, Pages 65-83

Evidence for FGF23 involvement in a bone-kidney axis regulating bone mineralization and systemic phosphate and vitamin D homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; DENTIN MATRIX PROTEIN 1; FIBROBLAST GROWTH FACTOR 23; PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; FIBROBLAST GROWTH FACTOR; PHOSPHATE; VITAMIN D;

EID: 84859536721     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0887-1_4     Document Type: Article
Times cited : (24)

References (114)
  • 1
    • 57449105957 scopus 로고    scopus 로고
    • Endocrine functions ofbone in mineral metabolism regulation
    • Quarles LD. Endocrine functions ofbone in mineral metabolism regulation. J Clin Invest2008;118(12):3820-8
    • (2008) J Clin Invest , vol.118 , Issue.12 , pp. 3820-3828
    • Quarles, L.D.1
  • 2
    • 0017747466 scopus 로고
    • Role of 1,25-dihydroxyvitamin D3 on intestinal phosphate absorption in rats with a normal vitamin D supply
    • Rizzoli R, Fleisch H, Bonjour JP. Role of 1,25-dihydroxyvitamin D3 on intestinal phosphate absorption in rats with a normal vitamin D supply. J Clin Invest 1977; 60(3):639-47
    • (1977) J Clin Invest , vol.60 , Issue.3 , pp. 639-647
    • Rizzoli, R.1    Fleisch, H.2    Bonjour, J.P.3
  • 3
    • 34250296228 scopus 로고
    • An interpretation of acute changes in plasma 45Ca following parathyroid hormone administration to thyroparathyroidectomized rats
    • Talmage RV, Doppelt SH, Fondren FB. An interpretation of acute changes in plasma 45Ca following parathyroid hormone administration to thyroparathyroidectomized rats. CalcifTissue Res 1976; 22(2):117-28
    • (1976) CalcifTissue Res , vol.22 , Issue.2 , pp. 117-128
    • Talmage, R.V.1    Doppelt, S.H.2    Fondren, F.B.3
  • 4
    • 0034878897 scopus 로고    scopus 로고
    • Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation
    • Ma YL, Cain RL, Halladay DL et al. Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. Endocrinology2001; 142(9):4047-54
    • (2001) Endocrinology , vol.142 , Issue.9 , pp. 4047-4054
    • Ma, Y.L.1    Cain, R.L.2    Halladay, D.L.3
  • 5
    • 0022644440 scopus 로고
    • Parathyroid hormone stimulates phosphate efflux through an apparently adenosine 3′,5′-monophosphate-independent process in rat parotid cell aggregates
    • Shiraki M, Gee MV, Baum BJ et al. Parathyroid hormone stimulates phosphate efflux through an apparently adenosine 3′,5′- monophosphate-independent process in rat parotid cell aggregates. Endocrinology 1986; 118(5):2009-15
    • (1986) Endocrinology , vol.118 , Issue.5 , pp. 2009-2015
    • Shiraki, M.1    Gee, M.V.2    Baum, B.J.3
  • 6
    • 69249205598 scopus 로고    scopus 로고
    • A paradigm of integrative physiology, the crosstalk between bone and energy metabolisms
    • Confavreux CB, Levine RL, Karsenty G. A paradigm of integrative physiology, the crosstalk between bone and energy metabolisms. Mol Cell Endocrinol 2009; 310(1-2):21-9
    • (2009) Mol Cell Endocrinol , vol.310 , Issue.1-2 , pp. 21-29
    • Confavreux, C.B.1    Levine, R.L.2    Karsenty, G.3
  • 7
    • 0034703619 scopus 로고    scopus 로고
    • Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
    • Yamashita T, Yoshioka M, Itoh N. Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain. Biochem Biophys Res Commun 2000; 277(2):494-8
    • (2000) Biochem Biophys Res Commun , vol.277 , Issue.2 , pp. 494-498
    • Yamashita, T.1    Yoshioka, M.2    Itoh, N.3
  • 8
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 2004; 20(11):563-9
    • (2004) Trends Genet , vol.20 , Issue.11 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 9
    • 38149134409 scopus 로고    scopus 로고
    • Functional evolutionary history ofthe mouse Fgfgene family
    • ItohN, Ornitz DM. Functional evolutionary history ofthe mouse Fgfgene family. Dev Dyn2008; 237(1):18-27
    • (2008) Dev Dyn , vol.237 , Issue.1 , pp. 18-27
    • Itoh, N.1    Ornitz, D.M.2
  • 10
    • 41649109108 scopus 로고    scopus 로고
    • BetaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c
    • Suzuki M, Uehara Y, Motomura-Matsuzaka K et al. betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c. Mol Endocrinol 2008; 22(4):1006-14
    • (2008) Mol Endocrinol , vol.22 , Issue.4 , pp. 1006-1014
    • Suzuki, M.1    Uehara, Y.2    Motomura-Matsuzaka, K.3
  • 11
    • 33646578195 scopus 로고    scopus 로고
    • Regulation of fibroblast growth factor-23 signaling by klotho
    • Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 2006; 281(10):6120-3
    • (2006) J Biol Chem , vol.281 , Issue.10 , pp. 6120-6123
    • Kurosu, H.1    Ogawa, Y.2    Miyoshi, M.3
  • 12
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • Urakawa I, Yamazaki Y, Shimada T et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006; 444(7120):770-4
    • (2006) Nature , vol.444 , Issue.7120 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3
  • 13
    • 26844564690 scopus 로고    scopus 로고
    • Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23
    • Yu X, Ibrahimi OA, Goetz R et al. Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23. Endocrinology 2005; 146(11):4647-56
    • (2005) Endocrinology , vol.146 , Issue.11 , pp. 4647-4656
    • Yu, X.1    Ibrahimi, O.A.2    Goetz, R.3
  • 14
    • 13844318061 scopus 로고    scopus 로고
    • Immunohistochemical localization of Klotho protein in brain, kidney and reproductive organs of mice
    • Li SA, Watanabe M, Yamada H et al. Immunohistochemical localization of Klotho protein in brain, kidney and reproductive organs of mice. Cell Struct Funct 2004; 29(4):91-9
    • (2004) Cell Struct Funct , vol.29 , Issue.4 , pp. 91-99
    • Li, S.A.1    Watanabe, M.2    Yamada, H.3
  • 15
    • 50249114540 scopus 로고    scopus 로고
    • Anti-FGF23 neutralizing antibodies show the physiological role and structural features ofFGF23
    • Yamazaki Y, Tamada T, Kasai N et al.. Anti-FGF23 neutralizing antibodies show the physiological role and structural features ofFGF23. J Bone Miner Res 2008; 23(9):1509-18
    • (2008) J Bone Miner Res , vol.23 , Issue.9 , pp. 1509-1518
    • Yamazaki, Y.1    Tamada, T.2    Kasai, N.3
  • 16
    • 33646367420 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D
    • Liu S, Tang W, Zhou J et al. Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 2006; l7(5):l305-l5
    • (2006) J Am Soc Nephrol , vol.17 , Issue.5 , pp. 1305-1315
    • Liu, S.1    Tang, W.2    Zhou, J.3
  • 17
    • 9244240970 scopus 로고    scopus 로고
    • Transgenic mice overexpressing human fibroblast growth factor 23 (Rl76Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders
    • Bai X, Miao D, Li J et al. Transgenic mice overexpressing human fibroblast growth factor 23 (Rl76Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders. Endocrinology 2004; l45(ll):5269-79
    • (2004) Endocrinology , vol.145 , Issue.11 , pp. 5269-5279
    • Bai, X.1    Miao, D.2    Li, J.3
  • 18
    • 3042634460 scopus 로고    scopus 로고
    • Transgenic mice expressing fibroblast growth factor 23 under the control of the alphal (I) collagen promoter exhibit growth retardation, osteomalacia and disturbed phosphatehomeostasis
    • Larsson T, Marsell R, Schipani E et al. Transgenic mice expressing fibroblast growth factor 23 under the control of the alphal(I) collagen promoter exhibit growth retardation, osteomalacia and disturbed phosphatehomeostasis. Endocrinology2004; l45(7):3087-94
    • (2004) Endocrinology , vol.145 , Issue.7 , pp. 3087-3094
    • Larsson, T.1    Marsell, R.2    Schipani, E.3
  • 19
    • 14344279878 scopus 로고    scopus 로고
    • Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
    • Shimada T, Mizutani S, Muto T et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad SciUSA200l;98(ll):6500-5
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.11 , pp. 6500-6505
    • Shimada, T.1    Mizutani, S.2    Muto, T.3
  • 20
    • 26844568409 scopus 로고    scopus 로고
    • Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism
    • Shimada T, Yamazaki Y, Takahashi M et al. Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism. Am J Physiol Renal Physiol 2005; 289(5):Fl088-95
    • (2005) Am J Physiol Renal Physiol , vol.289 , Issue.5
    • Shimada, T.1    Yamazaki, Y.2    Takahashi, M.3
  • 21
    • 0037462746 scopus 로고    scopus 로고
    • Human fibroblast growth factor-23 mutants suppressNa+-dependent phosphate cotransport activity and lalpha,25-dihydroxyvitamin D3 production
    • Saito H, Kusano K, Kinosaki M. Human fibroblast growth factor-23 mutants suppressNa+-dependent phosphate cotransport activity and lalpha,25- dihydroxyvitamin D3 production. J Biol Chem 2003; 278(4):2206-ll
    • (2003) J Biol Chem , vol.278 , Issue.4
    • Saito, H.1    Kusano, K.2    Kinosaki, M.3
  • 22
    • 34248587172 scopus 로고    scopus 로고
    • Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population
    • Zhang F, Zhai G, Kato BS et al. Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population. Osteoarthritis Cartilage, 2007
    • (2007) Osteoarthritis Cartilage
    • Zhang, F.1    Zhai, G.2    Kato, B.S.3
  • 23
    • 0030724491 scopus 로고    scopus 로고
    • Mutation of the mouse klotho gene leads to a syndrome resembling ageing
    • Kuro-o M, Matsumura Y, Aizawa H et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature l997; 390(6655):45-5l
    • (1997) Nature , vol.390 , Issue.6655 , pp. 45-51
    • Kuro-O, M.1    Matsumura, Y.2    Aizawa, H.3
  • 24
    • 36849017126 scopus 로고    scopus 로고
    • The parathyroid is a target organ for FGF23 in rats
    • Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007; ll7(l2):4003-8
    • (2007) J Clin Invest , vol.117 , Issue.12 , pp. 4003-4008
    • Ben-Dov, I.Z.1    Galitzer, H.2    Lavi-Moshayoff, V.3
  • 25
    • 44449118964 scopus 로고    scopus 로고
    • Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro
    • Wang H, Yoshiko Y, Yamamoto R et al. Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro. J Bone Miner Res 2008; 23(6):939-48
    • (2008) J Bone Miner Res , vol.23 , Issue.6 , pp. 939-948
    • Wang, H.1    Yoshiko, Y.2    Yamamoto, R.3
  • 27
    • 1642416884 scopus 로고    scopus 로고
    • Targeted ablation ofFgf23 demonstrates an essential physiological role ofFGF23 in phosphate and vitamin D metabolism
    • Shimada T, Kakitani M, Yamazaki Y etal. Targeted ablation ofFgf23 demonstrates an essential physiological role ofFGF23 in phosphate and vitamin D metabolism. J Clin Invest 2004; ll3(4):56l-8
    • (2004) J Clin Invest , vol.113 , Issue.4 , pp. 561-568
    • Shimada, T.1    Kakitani, M.2    Yamazaki, Y.3
  • 28
    • 9644303231 scopus 로고    scopus 로고
    • Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis and reverses hypophosphatemia in Phex-deficient mice
    • Sitara D, Razzaque MS, Hesse M et al. Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol 2004; 23(7):42l-32
    • (2004) Matrix Biol , vol.23 , Issue.7
    • Sitara, D.1    Razzaque, M.S.2    Hesse, M.3
  • 29
    • 33846566785 scopus 로고    scopus 로고
    • Ablation of vitamin D signaling rescues bone mineral and glucose homeostasis in Fgf-23 deficient mice
    • Hesse M, Frohlich LF, Zeitz U et al. Ablation of vitamin D signaling rescues bone, mineral and glucose homeostasis in Fgf-23 deficient mice. Matrix Biol2007; 26(2):75-84
    • (2007) Matrix Biol , vol.26 , Issue.2 , pp. 75-84
    • Hesse, M.1    Frohlich, L.F.2    Zeitz, U.3
  • 30
    • 34247545717 scopus 로고    scopus 로고
    • Genetic ablation of vitamin d activation pathway reverses biochemical and skeletal anomalies in fgf-23-null animals
    • Sitara D, Razzaque MS, St-Arnaud R et al. Genetic ablation of vitamin d activation pathway reverses biochemical and skeletal anomalies in fgf-23-null animals. Am J Pathol 2006; l69(6):2l6l-70
    • (2006) Am J Pathol , vol.169 , Issue.6 , pp. 2161-2170
    • Sitara, D.1    Razzaque, M.S.2    St-Arnaud, R.3
  • 31
    • 34249914670 scopus 로고    scopus 로고
    • Role of Hyperphosphatemia and l,25 OH2D3 in Vascular Calcifications and Mortality in FGF23 Null Mice
    • Stubbs J, Liu S, Tang W et al. Role of Hyperphosphatemia and l,25(OH2D3 in Vascular Calcifications and Mortality in FGF23 Null Mice. J Am Soc Nephrol 2007; 17:689a
    • (2007) J Am Soc Nephrol , vol.17
    • Stubbs, J.1    Liu, S.2    Tang, W.3
  • 32
    • 42149130855 scopus 로고    scopus 로고
    • A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism
    • Brownstein CA, Adler F, Nelson-Williams C et al. A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism. Proc Natl Acad Sci USA 2008; l05(9):3455-60
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.9 , pp. 3455-3460
    • Brownstein, C.A.1    Adler, F.2    Nelson-Williams, C.3
  • 33
    • 0013118819 scopus 로고    scopus 로고
    • The autosomal dominant hypophosphatemic rickets Rl76Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency
    • Bai XY, Miao D, Goltzman D et al. The autosomal dominant hypophosphatemic rickets Rl76Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency. J Biol Chem2003; 278(ll):9843-9
    • (2003) J Biol Chem , vol.278 , Issue.11 , pp. 9843-9849
    • Bai, X.Y.1    Miao, D.2    Goltzman, D.3
  • 34
    • 3242656464 scopus 로고    scopus 로고
    • FGF23 is processed by proprotein convertases but notby PHEX
    • Benet-Pages A, Lorenz-Depiereux B, Zischka H et al. FGF23 is processed by proprotein convertases but notby PHEX. Bone 2004; 35(2):455-62
    • (2004) Bone , vol.35 , Issue.2 , pp. 455-462
    • Benet-Pages, A.1    Lorenz-Depiereux, B.2    Zischka, H.3
  • 35
    • 33750454816 scopus 로고    scopus 로고
    • Loss of DMPl causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism
    • Feng JQ, Ward LM, Liu S et al. Loss of DMPl causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet 2006; 38(ll):l3l0-5
    • (2006) Nat Genet , vol.38 , Issue.11 , pp. 1310-1315
    • Feng, J.Q.1    Ward, L.M.2    Liu, S.3
  • 36
    • 33750427897 scopus 로고    scopus 로고
    • DMPl mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis
    • Lorenz-Depiereux B, Bastepe M, Benet-Pages A et al. DMPl mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis. Nat Genet 2006;38(ll):l248-50
    • (2006) Nat Genet , vol.38 , Issue.11 , pp. 1248-1250
    • Lorenz-Depiereux, B.1    Bastepe, M.2    Benet-Pages, A.3
  • 37
    • 28144464147 scopus 로고    scopus 로고
    • DMPl depletion decreases bone mineralization in vivo: An FTIR imaging analysis
    • Ling Y, Rios HF, Myers ER et al. DMPl depletion decreases bone mineralization in vivo: an FTIR imaging analysis. J Bone Miner Res 2005; 20(l2):2l69-77
    • (2005) J Bone Miner Res , vol.20 , Issue.12
    • Ling, Y.1    Rios, H.F.2    Myers, E.R.3
  • 38
    • 20244368616 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia
    • Jonsson KB, Zahradnik R, Larsson T et al. Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med 2003; 348(l7):l656-63
    • (2003) N Engl J Med , vol.348 , Issue.17
    • Jonsson, K.B.1    Zahradnik, R.2    Larsson, T.3
  • 39
    • 0141525564 scopus 로고    scopus 로고
    • Serum FGF23 levels in normal and disordered phosphorus homeostasis
    • Weber TJ, Liu S, Indridason OS et al. Serum FGF23 levels in normal and disordered phosphorus homeostasis. J Bone Miner Res 2003; l8(7):l227-34
    • (2003) J Bone Miner Res , vol.18 , Issue.7 , pp. 1227-1234
    • Weber, T.J.1    Liu, S.2    Indridason, O.S.3
  • 40
    • 85047693146 scopus 로고    scopus 로고
    • Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent
    • Berndt T, Craig TA, Bowe AE et al. Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent. J Clin Invest 2003; ll2(5):785-94
    • (2003) J Clin Invest , vol.112 , Issue.5 , pp. 785-794
    • Berndt, T.1    Craig, T.A.2    Bowe, A.E.3
  • 41
    • 0030954146 scopus 로고    scopus 로고
    • Cloning and sequencing of human PEX from a bone cDNA library: Evidence for its developmental stage-specific regulation in osteoblasts
    • Guo R, Quarles LD. Cloning and sequencing of human PEX from a bone cDNA library: evidence for its developmental stage-specific regulation in osteoblasts. J Bone Miner Res l997; l2(7):l009-l7
    • (1997) J Bone Miner Res , vol.12 , Issue.7 , pp. 1009-1017
    • Guo, R.1    Quarles, L.D.2
  • 42
    • 0029160578 scopus 로고
    • The HYP Consortium, A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemicrickets
    • The HYP Consortium, A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemicrickets. NatGenet l995; ll (2):l30-6
    • (1995) Nat Genet , vol.11 , Issue.2 , pp. 130-136
  • 43
    • 84859773412 scopus 로고    scopus 로고
    • Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts
    • Thompson DL, Sabbagh Y, Tenenhouse HS et al. Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts. J Bone Miner Res 2002; l7(2):3ll-20
    • (2002) J Bone Miner Res , vol.L7 , Issue.2
    • Thompson, D.L.1    Sabbagh, Y.2    Tenenhouse, H.S.3
  • 44
    • 0141844575 scopus 로고    scopus 로고
    • Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX
    • Liu S, Guo R, Simpson LG et al. Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX. J Biol Chem 2003; 278(39):374l9-26
    • (2003) J Biol Chem , vol.278 , Issue.39
    • Liu, S.1    Guo, R.2    Simpson, L.G.3
  • 45
    • 19944430581 scopus 로고    scopus 로고
    • Mutations that cause osteoglophonic dysplasia define novel roles for FGFRl in bone elongation
    • White KE, Cabral JM, Davis SI et al. Mutations that cause osteoglophonic dysplasia define novel roles for FGFRl in bone elongation. Am J Hum Genet 2005; 76(2):36l-7
    • (2005) Am J Hum Genet , vol.76 , Issue.2
    • White, K.E.1    Cabral, J.M.2    Davis, S.I.3
  • 46
    • 13544270218 scopus 로고    scopus 로고
    • An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia
    • Benet-Pages A, Orlik P, Strom TM et al. An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. Hum Mol Genet 2005; l4(3):385-90
    • (2005) Hum Mol Genet , vol.14 , Issue.3 , pp. 385-390
    • Benet-Pages, A.1    Orlik, P.2    Strom, T.M.3
  • 47
    • 23844457598 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 mutants causing familial tumoral calcinosis are differentially processed
    • Larsson T, Davis SI, Garringer HJ et al. Fibroblast growth factor-23 mutants causing familial tumoral calcinosis are differentially processed. Endocrinology 2005; l46(9):3883-9l
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3883-3891
    • Larsson, T.1    Davis, S.I.2    Garringer, H.J.3
  • 48
    • 0021813494 scopus 로고    scopus 로고
    • Genetic transmission of tumoral calcinosis: Autosomal dominant with variable clinical expressivity
    • Lyles KW, Burkes EJ, Ellis GJ et al. Genetic transmission of tumoral calcinosis: autosomal dominant with variable clinical expressivity. J Clin Endocrinol Metab l985; 60(6):l093-6
    • J Clin Endocrinol Metab l985 , vol.60 , Issue.6
    • Lyles, K.W.1    Burkes, E.J.2    Ellis, G.J.3
  • 49
    • 34848871595 scopus 로고    scopus 로고
    • A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis
    • Ichikawa S, Imel EA, Kreiter ML et al. A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. J Clin Invest 2007; ll7(9):2684-269l
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2684-2691
    • Ichikawa, S.1    Imel, E.A.2    Kreiter, M.L.3
  • 50
    • 33749015193 scopus 로고    scopus 로고
    • A deleterious mutation in SAMD9 causes normophosphatemic familial tumoral calcinosis
    • Topaz O, Indelman M, Chefetz I et al. A deleterious mutation in SAMD9 causes normophosphatemic familial tumoral calcinosis. Am J Hum Genet 2006; 79(4):759-64
    • (2006) Am J Hum Genet , vol.79 , Issue.4 , pp. 759-764
    • Topaz, O.1    Indelman, M.2    Chefetz, I.3
  • 51
    • 0030035111 scopus 로고    scopus 로고
    • CDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D- galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3
    • Bennett EP, Hassan H, Clausen H. cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N- acetylgalactosaminyltransferase, GalNAc-t3. J Biol Chem l996; 27l(29):l7006-l2
    • (1996) J Biol Chem , vol.271 , Issue.29 , pp. 17006-17012
    • Bennett, E.P.1    Hassan, H.2    Clausen, H.3
  • 52
    • 33846867744 scopus 로고    scopus 로고
    • Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice
    • Segawa H, Yamanaka S, Ohno Y et al. Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice. Am J Physiol Renal Physiol 2007; 292(2):F769-79
    • (2007) Am J Physiol Renal Physiol , vol.292 , Issue.2
    • Segawa, H.1    Yamanaka, S.2    Ohno, Y.3
  • 53
    • 0036150953 scopus 로고    scopus 로고
    • Mediation of unusually high concentrations of l,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal lalpha-hydroxylase gene
    • Yoshida T, Fujimori T, Nabeshima Y. Mediation of unusually high concentrations of l,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal lalpha-hydroxylase gene. Endocrinology2002; l43(2):683-9
    • (2002) Endocrinology , vol.143 , Issue.2 , pp. 683-689
    • Yoshida, T.1    Fujimori, T.2    Nabeshima, Y.3
  • 54
    • 33646238028 scopus 로고    scopus 로고
    • Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process
    • Razzaque MS, Sitara D, Taguchi T et al. Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J 2006; 20(6):720-2
    • (2006) FASEB J , vol.20 , Issue.6 , pp. 720-722
    • Razzaque, M.S.1    Sitara, D.2    Taguchi, T.3
  • 55
    • 33644818657 scopus 로고    scopus 로고
    • Hypophosphatemia: An evidence-based approach to its clinical consequences and management
    • Amanzadeh J, Reilly RF, Jr. Hypophosphatemia: an evidence-based approach to its clinical consequences and management. Nat Clin Pract Nephrol 2006; 2(3):l36-48
    • (2006) Nat Clin Pract Nephrol , vol.2 , Issue.3
    • Amanzadeh, J.1    Reilly Jr., R.F.2
  • 56
    • 3543139492 scopus 로고    scopus 로고
    • Mineral metabolism, mortality and morbidity in maintenance hemodialysis
    • Block GA, Klassen PS, Lazarus JM et al. Mineral metabolism, mortality and morbidity in maintenance hemodialysis. J Am Soc Nephrol 2004; l5(8):2208-l8
    • (2004) J Am Soc Nephrol , vol.15 , Issue.8 , pp. 2208-2218
    • Block, G.A.1    Klassen, P.S.2    Lazarus, J.M.3
  • 57
    • 33845296928 scopus 로고    scopus 로고
    • Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts
    • Masuyama R, Stockmans I, Torrekens S et al. Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts. J Clin Invest 2006; ll6(l2):3l50-9
    • (2006) J Clin Invest , vol.116 , Issue.12 , pp. 3150-3159
    • Masuyama, R.1    Stockmans, I.2    Torrekens, S.3
  • 58
    • 70350330869 scopus 로고    scopus 로고
    • Bone formation regulates circulating concentrations of fibroblast growth factor 23
    • Samadfam R, Richard C, Nguyen-Yamamoto L et al. Bone formation regulates circulating concentrations of fibroblast growth factor 23. Endocrinology 2009; l50(ll):4835-45
    • (2009) Endocrinology , vol.150 , Issue.11 , pp. 4835-4845
    • Samadfam, R.1    Richard, C.2    Nguyen-Yamamoto, L.3
  • 59
    • 9644290893 scopus 로고    scopus 로고
    • Fibroblast growth factor 23, parathyroid hormone and 1alpha,25- dihydroxyvitamin D in surgically treated primary hyperparathyroidism
    • Tebben PJ, Singh RJ, Clarke BL et al. Fibroblast growth factor 23, parathyroid hormone and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism. Mayo Clin Proc 2004; 79(l2):l508-l3
    • (2004) Mayo Clin Proc , vol.79 , Issue.12
    • Tebben, P.J.1    Singh, R.J.2    Clarke, B.L.3
  • 60
    • 34948866160 scopus 로고    scopus 로고
    • Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism
    • Kawata T, Imanishi Y, Kobayashi K et al. Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism. J Am Soc Nephrol 2007; l8(l0):2683-8
    • (2007) J Am Soc Nephrol , vol.18 , Issue.10 , pp. 2683-2688
    • Kawata, T.1    Imanishi, Y.2    Kobayashi, K.3
  • 61
    • 67649099265 scopus 로고    scopus 로고
    • Regulation of fibroblast growth factor 23 production in bone in uremic rats
    • Saji F, Shiizaki K, Shimada S et al. Regulation of fibroblast growth factor 23 production in bone in uremic rats. Nephron Physiol 2009; lll(4):p59-66
    • (2009) Nephron Physiol , vol.111 , Issue.4 , pp. 59-66
    • Saji, F.1    Shiizaki, K.2    Shimada, S.3
  • 62
    • 27844501565 scopus 로고    scopus 로고
    • Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and l,25-dihydroxyvitamin D metabolism in mice
    • Perwad F, Azam N, Zhang MY et al. Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and l,25-dihydroxyvitamin D metabolism in mice. Endocrinology 2005; l46(l2):5358-64
    • (2005) Endocrinology , vol.146 , Issue.12 , pp. 5358-5364
    • Perwad, F.1    Azam, N.2    Zhang, M.Y.3
  • 63
    • 15944376583 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men
    • Ferrari SL, Bonjour JP, Rizzoli R. Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab 2005; 90(3):l5l9-24
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.3
    • Ferrari, S.L.1    Bonjour, J.P.2    Rizzoli, R.3
  • 64
    • 33845322655 scopus 로고    scopus 로고
    • Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men
    • Nishida Y, Taketani Y, Yamanaka-Okumura H et al. Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men. Kidney Int 2006; 70(l2):2l4l-7
    • (2006) Kidney Int , vol.70 , Issue.12
    • Nishida, Y.1    Taketani, Y.2    Yamanaka-Okumura, H.3
  • 65
    • 77649153956 scopus 로고    scopus 로고
    • Oral phosphate supplementation corrects hypophosphatemia and normalizes plasma FGF23 and 25-hydroxyvitamin D3 levels in women with chronic metabolic acidosis
    • Domrongkitchaiporn S, Disthabanchong S, Cheawchanthanakij R et al. Oral phosphate supplementation corrects hypophosphatemia and normalizes plasma FGF23 and 25-hydroxyvitamin D3 levels in women with chronic metabolic acidosis. Exp Clin Endocrinol Diabetes 20l0; ll8(2):l05-l2
    • (2010) Exp Clin Endocrinol Diabetes , vol.118 , Issue.2 , pp. 105-112
    • Domrongkitchaiporn, S.1    Disthabanchong, S.2    Cheawchanthanakij, R.3
  • 66
    • 40849083626 scopus 로고    scopus 로고
    • FGF23 is elevated in Gambian children with rickets
    • Prentice A, Ceesay M, Nigdikar Setal. FGF23 is elevated in Gambian children with rickets. Bone 2008; 42(4):788-97
    • (2008) Bone , vol.42 , Issue.4 , pp. 788-797
    • Prentice, A.1    Ceesay, M.2    Nigdikar, S.3
  • 67
    • 40949151916 scopus 로고    scopus 로고
    • Tumor producing fibroblast growth factor 23 localized by two-staged venous sampling
    • van Boekel G, Ruinemans-Koerts J, Joosten F et al. Tumor producing fibroblast growth factor 23 localized by two-staged venous sampling. Eur J Endocrinol 2008; l58(3):43l-7
    • (2008) Eur J Endocrinol , vol.158 , Issue.3 , pp. 431-437
    • Van Boekel, G.1    Ruinemans-Koerts, J.2    Joosten, F.3
  • 68
    • 10744226781 scopus 로고    scopus 로고
    • MEPE has the properties of an osteoblastic phosphatonin and minhibin
    • Rowe PS, Kumagai Y, Gutierrez G et al. MEPE has the properties of an osteoblastic phosphatonin and minhibin. Bone 2004; 34(2):303-l9
    • (2004) Bone , vol.34 , Issue.2
    • Rowe, P.S.1    Kumagai, Y.2    Gutierrez, G.3
  • 69
    • 33947385485 scopus 로고    scopus 로고
    • Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity
    • Liu S, Rowe PS, Vierthaler L et al. Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity. J Endocrinol 2007; l92(l):26l-7
    • (2007) J Endocrinol , vol.192 , Issue.50 , pp. 261-267
    • Liu, S.1    Rowe, P.S.2    Vierthaler, L.3
  • 70
    • 38849170631 scopus 로고    scopus 로고
    • Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia
    • Yuan B, Takaiwa M, Clemens TL et al. Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia. J Clin Invest 2008; ll8(2):722-34
    • (2008) J Clin Invest , vol.118 , Issue.2 , pp. 722-734
    • Yuan, B.1    Takaiwa, M.2    Clemens, T.L.3
  • 71
    • 0034805353 scopus 로고    scopus 로고
    • FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate
    • Bowe AE, Finnegan R, Jan de Beur SM et al. FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate. Biochem Biophys Res Commun 200l; 284(4):977-8l
    • (2001) Biochem Biophys Res Commun , vol.284 , Issue.4
    • Bowe, A.E.1    Finnegan, R.2    Jan De Beur, S.M.3
  • 72
    • 0034786083 scopus 로고    scopus 로고
    • Analysis of recombinant Phex: An endopeptidase in search of a substrate
    • Guo R, Liu S, Spurney RF et al. Analysis of recombinant Phex: an endopeptidase in search of a substrate. Am J Physiol Endocrinol Metab 200l; 28l(4):E837-47
    • (2001) Am J Physiol Endocrinol Metab , vol.28 L , Issue.4
    • Guo, R.1    Liu, S.2    Spurney, R.F.3
  • 73
    • 0038343128 scopus 로고    scopus 로고
    • Human recombinant endopeptidase PHEX has a strict Sl′ specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein
    • Campos M, Couture C, Hirata IY et al. Human recombinant endopeptidase PHEX has a strict Sl′ specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein. Biochem J 2003; 373(Pt l):27l-9
    • (2003) Biochem J , vol.373 , Issue.PART 1
    • Campos, M.1    Couture, C.2    Hirata, I.Y.3
  • 74
    • 52949134423 scopus 로고    scopus 로고
    • MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: An inhibition regulated by PHEX cleavage of ASARM
    • Addison WN, Nakano Y, Loisel T et al. MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM. J Bone Miner Res 2008; 23(l0):l638-49
    • (2008) J Bone Miner Res , vol.23 , Issue.10
    • Addison, W.N.1    Nakano, Y.2    Loisel, T.3
  • 75
    • 41549134046 scopus 로고    scopus 로고
    • Degradation ofMEPE DMPl andrelease ofSIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP
    • Martin A, David V, Laurence JS etal. Degradation ofMEPE, DMPl andrelease ofSIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP. Endocrinology 2008; l49(4):l757-72
    • (2008) Endocrinology , vol.149 , Issue.4 , pp. 1757-1772
    • Martin, A.1    David, V.2    Laurence, J.S.3
  • 76
    • 26944499850 scopus 로고    scopus 로고
    • Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia
    • Liu S, Brown TA, Zhou J et al. Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia. J Am Soc Nephrol 2005; l6(6):l645-53
    • (2005) J Am Soc Nephrol , vol.16 , Issue.6
    • Liu, S.1    Brown, T.A.2    Zhou, J.3
  • 77
    • 12244263475 scopus 로고    scopus 로고
    • Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression
    • Bai X, Miao D, Panda D et al. Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression. Mol Endocrinol 2002; l6(l2):29l3-25
    • (2002) Mol Endocrinol , vol.16 , Issue.12 , pp. 2913-2925
    • Bai, X.1    Miao, D.2    Panda, D.3
  • 78
    • 20844431717 scopus 로고    scopus 로고
    • Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype
    • Erben RG, Mayer D, Weber K et al. Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype. J Bone Miner Res 2005; 20(7):ll49-60
    • (2005) J Bone Miner Res , vol.20 , Issue.7
    • Erben, R.G.1    Mayer, D.2    Weber, K.3
  • 79
    • 0036479315 scopus 로고    scopus 로고
    • Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype
    • Liu S, Guo R, Tu Q et al. Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype. J Biol Chem 2002; 277(5):3686-97
    • (2002) J Biol Chem , vol.277 , Issue.5 , pp. 3686-3697
    • Liu, S.1    Guo, R.2    Tu, Q.3
  • 80
    • 33750454816 scopus 로고    scopus 로고
    • Loss of DMPl causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism
    • Feng JQ, Ward LM, Liu S et al. Loss of DMPl causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet, 2006
    • (2006) Nat Genet
    • Feng, J.Q.1    Ward, L.M.2    Liu, S.3
  • 81
    • 0037931728 scopus 로고    scopus 로고
    • Dual functional roles of dentin matrix protein l. Implications in biomineralization and gene transcription by activation of intracellular Ca2+ store
    • Narayanan K, Ramachandran A, Hao J et al. Dual functional roles of dentin matrix protein l. Implications in biomineralization and gene transcription by activation of intracellular Ca2+ store. J Biol Chem 2003; 278(l9):l7500-8
    • (2003) J Biol Chem , vol.278 , Issue.19
    • Narayanan, K.1    Ramachandran, A.2    Hao, J.3
  • 82
    • 4644312298 scopus 로고    scopus 로고
    • Expression of SIBLINGs and their partner MMPs in salivary glands
    • Ogbureke KU, Fisher LW. Expression of SIBLINGs and their partner MMPs in salivary glands. J Dent Res 2004; 83(9):664-70
    • (2004) J Dent Res , vol.83 , Issue.9 , pp. 664-670
    • Ogbureke, K.U.1    Fisher, L.W.2
  • 83
    • 68849097845 scopus 로고    scopus 로고
    • FGF23 is aputative marker for bone healing and regeneration
    • Goebel S, Lienau J, Rammoser Uetal. FGF23 is aputative marker for bone healing and regeneration. J Orthop Res 2009
    • (2009) J Orthop Res
    • Goebel, S.1    Lienau, J.2    Rammoser, U.3
  • 84
    • 57449105121 scopus 로고    scopus 로고
    • Studies of the DMPl 57-kDa functional domain both in vivo and in vitro
    • Lu Y, Qin C, Xie Y et al. Studies of the DMPl 57-kDa functional domain both in vivo and in vitro. Cells Tissues Organs 2009; l89(l-4):l75-85
    • (2009) Cells Tissues Organs , vol.189 , Issue.1-4 , pp. 175-185
    • Lu, Y.1    Qin, C.2    Xie, Y.3
  • 85
    • 84859772435 scopus 로고    scopus 로고
    • Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice
    • Aug
    • Liu S, Tang W, Zhou J et al. Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice. Am J Physiol Endocrinol Metab 2008 Aug;295(2):E254-6l
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , Issue.2
    • Liu, S.1    Tang, W.2    Zhou, J.3
  • 86
    • 0031796266 scopus 로고    scopus 로고
    • Intrinsic mineralization defect in Hyp mouse osteoblasts
    • Xiao ZS, Crenshaw M, Guo R et al. Intrinsic mineralization defect in Hyp mouse osteoblasts. Am J Physiol l998; 275(4 Pt l):E700-8
    • (1998) Am J Physiol , vol.275 , Issue.4 PART 1
    • Xiao, Z.S.1    Crenshaw, M.2    Guo, R.3
  • 87
  • 89
    • 0020028750 scopus 로고
    • Bone response to phosphate and vitamin D metabolites in the hypophosphatemic male mouse
    • Marie PJ, Travers R, Glorieux FH. Bone response to phosphate and vitamin D metabolites in the hypophosphatemic male mouse. Calcif Tissue Int l982; 34(2):l58-64
    • (1982) Calcif Tissue Int , vol.34 , Issue.2 , pp. 158-164
    • Marie, P.J.1    Travers, R.2    Glorieux, F.H.3
  • 90
    • 50849104780 scopus 로고    scopus 로고
    • Genetic evidence of serum phosphate-independent functions of FGF-23 on bone
    • Sitara D, Kim S, Razzaque MS et al. Genetic evidence of serum phosphate-independent functions of FGF-23 on bone. PLoS Genet 2008; 4(8):el000l54
    • (2008) PLoS Genet , vol.4 , Issue.8
    • Sitara, D.1    Kim, S.2    Razzaque, M.S.3
  • 91
    • 57149099628 scopus 로고    scopus 로고
    • FGFR3 and 4 do not mediate renal effectso of FGF23 in vivo
    • In Press
    • Liu S, Vierthaler L, Tang W et al. FGFR3 and 4 do not mediate renal effectso of FGF23 in vivo. J Am Soc Nephrol 2008; In Press
    • (2008) J Am Soc Nephrol
    • Liu, S.1    Vierthaler, L.2    Tang, W.3
  • 92
    • 1642441997 scopus 로고    scopus 로고
    • Dentin matrix protein l immobilized on type i collagen fibrils facilitates apatite deposition in vitro
    • He G, George A. Dentin matrix protein l immobilized on type I collagen fibrils facilitates apatite deposition in vitro. J Biol Chem 2004; 279(l2):ll649-56
    • (2004) J Biol Chem , vol.279 , Issue.12
    • He, G.1    George, A.2
  • 93
    • 33748376254 scopus 로고    scopus 로고
    • Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin
    • Rowe PS, Matsumoto N, Jo OD et al. Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin. Bone, 2006
    • (2006) Bone
    • Rowe, P.S.1    Matsumoto, N.2    Jo, O.D.3
  • 94
    • 22844440951 scopus 로고    scopus 로고
    • Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates
    • Laize V, Martel P, Viegas CS et al. Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates. J Biol Chem 2005; 280(29):26659-68
    • (2005) J Biol Chem , vol.280 , Issue.29 , pp. 26659-26668
    • Laize, V.1    Martel, P.2    Viegas, C.S.3
  • 95
    • 0030947025 scopus 로고    scopus 로고
    • Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
    • Luo G, Ducy P, McKee MD et al. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature l997; 386(6620):78-8l
    • (1997) Nature , vol.386 , Issue.6620 , pp. 78-81
    • Luo, G.1    Ducy, P.2    McKee, M.D.3
  • 96
    • 33645968982 scopus 로고    scopus 로고
    • Role of matrix Gla protein in parathyroid hormone inhibition of osteoblast mineralization
    • Gopalakrishnan R, Suttamanatwong S, Carlson AE et al. Role of matrix Gla protein in parathyroid hormone inhibition of osteoblast mineralization. Cells Tissues Organs 2005; l8l(3-4):l66-75
    • (2005) Cells Tissues Organs , vol.181 , Issue.3-4 , pp. 166-175
    • Gopalakrishnan, R.1    Suttamanatwong, S.2    Carlson, A.E.3
  • 97
    • 0034711305 scopus 로고    scopus 로고
    • Thrombospondin-4 binds specifically to both collagenous and noncollagenous extracellular matrix proteins via its C-terminal domains
    • Narouz-Ott L, Maurer P, Nitshce DP et al. Thrombospondin-4 binds specifically to both collagenous and noncollagenous extracellular matrix proteins via its C-terminal domains. J Biol Chem 2000; 275(47):37ll0-7
    • (2000) J Biol Chem , vol.275 , Issue.47
    • Narouz-Ott, L.1    Maurer, P.2    Nitshce, D.P.3
  • 98
    • 44849140776 scopus 로고    scopus 로고
    • Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-l, thrombospondin-3, thrombospondin-5 and type IX collagen
    • Posey KL, Hankenson K, Veerisetty AC et al. Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-l, thrombospondin-3, thrombospondin-5 and type IX collagen. Am J Pathol 2008; l72(6):l664-74
    • (2008) Am J Pathol , vol.172 , Issue.6 , pp. 1664-1674
    • Posey, K.L.1    Hankenson, K.2    Veerisetty, A.C.3
  • 99
    • 20744460867 scopus 로고    scopus 로고
    • Mice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties ofbone and have accelerated development of the femoral head
    • Hankenson KD, Hormuzdi SG, Meganck JA et al. Mice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties ofbone and have accelerated development of the femoral head. Mol Cell Biol 2005; 25(l3):5599-606
    • (2005) Mol Cell Biol , vol.25 , Issue.13 , pp. 5599-5606
    • Hankenson, K.D.1    Hormuzdi, S.G.2    Meganck, J.A.3
  • 100
    • 33749261278 scopus 로고    scopus 로고
    • Constitutive expression ofthrombospondin l inMC3T3-El osteoblastic cells inhibits mineralization
    • Ueno A, Miwa Y, Miyoshi K et al. Constitutive expression ofthrombospondin l inMC3T3-El osteoblastic cells inhibits mineralization. J Cell Physiol 2006; 209(2):322-32
    • (2006) J Cell Physiol , vol.209 , Issue.2 , pp. 322-332
    • Ueno, A.1    Miwa, Y.2    Miyoshi, K.3
  • 101
    • 0025944564 scopus 로고
    • Carbonic anhydrase II deficiency syndrome in a Belgian family is caused by a point mutation at an invariant histidine residue (l07 His-Tyr): Complete structure of the normal human CAII gene
    • Venta PJ, Welty RJ, Johnson TM et al. Carbonic anhydrase II deficiency syndrome in a Belgian family is caused by a point mutation at an invariant histidine residue (l07 His-Tyr): complete structure of the normal human CAII gene. Am J Hum Genet l99l; 49(5):l082-90
    • (1991) Am J Hum Genet , vol.49 , Issue.5 , pp. 1082-1090
    • Venta, P.J.1    Welty, R.J.2    Johnson, T.M.3
  • 102
    • 49649122544 scopus 로고    scopus 로고
    • Direct binding of integrin alphavbeta3 to FGFl plays a role in FGFl signaling
    • Mori S, Wu CY, Yamaji S et al. Direct binding of integrin alphavbeta3 to FGFl plays a role in FGFl signaling. J Biol Chem 2008; 283(26):l8066-75
    • (2008) J Biol Chem , vol.283 , Issue.26
    • Mori, S.1    Wu, C.Y.2    Yamaji, S.3
  • 103
  • 104
    • 12344250943 scopus 로고    scopus 로고
    • Surface Plasmon Resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: A model for impaired mineralization in X-linked rickets (HYP)
    • Rowe PS, Garrett IR, Schwarz PM et al. Surface Plasmon Resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP). Bone 2005; 36(l):33-46
    • (2005) Bone , vol.36 , Issue.50 , pp. 33-46
    • Rowe, P.S.1    Garrett, I.R.2    Schwarz, P.M.3
  • 105
    • 33846938087 scopus 로고    scopus 로고
    • Rescue of odontogenesis in Dmpl-deficient mice by targeted re-expression of DMPl reveals roles for DMPl in early odontogenesis and dentin apposition in vivo
    • Lu Y, Ye L, Yu S et al. Rescue of odontogenesis in Dmpl-deficient mice by targeted re-expression of DMPl reveals roles for DMPl in early odontogenesis and dentin apposition in vivo. Dev Biol 2007; 303(l):l9l-20l
    • (2007) Dev Biol , vol.303 , Issue.50
    • Lu, Y.1    Ye, L.2    Yu, S.3
  • 106
    • 0035142415 scopus 로고    scopus 로고
    • Transcriptional regulation of alpha 2 (I) collagen gene expression by fibroblast growth factor-2 in MC3T3-El osteoblast-like cells
    • Fang MA, Glackin CA, Sadhu A et al. Transcriptional regulation of alpha 2(I) collagen gene expression by fibroblast growth factor-2 in MC3T3-El osteoblast-like cells. J Cell Biochem 200l; 80(4):550-9
    • (2001) J Cell Biochem , vol.80 , Issue.4 , pp. 550-559
    • Fang, M.A.1    Glackin, C.A.2    Sadhu, A.3
  • 107
    • 0042838268 scopus 로고    scopus 로고
    • BFGF administration lowers the phosphate threshold for mineralization in bone marrow stromal cells
    • Nauman EA, Sakata T, Keaveny TM et al. bFGF administration lowers the phosphate threshold for mineralization in bone marrow stromal cells. Calcif Tissue Int 2003; 73(2):l47-52
    • (2003) Calcif Tissue Int , vol.73 , Issue.2
    • Nauman, E.A.1    Sakata, T.2    Keaveny, T.M.3
  • 108
    • 20444388816 scopus 로고    scopus 로고
    • FGF7-an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors
    • Carpenter TO, Ellis BK, Insogna KL et al. FGF7-an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors. J Clin Endocrinol Metab, 2004
    • (2004) J Clin Endocrinol Metab
    • Carpenter, T.O.1    Ellis, B.K.2    Insogna, K.L.3
  • 109
    • 59449106881 scopus 로고    scopus 로고
    • Normal FGF23 levels in adult idiopathic phosphate diabetes
    • Laroche M, Boyer JF, Jahafar H et al. Normal FGF23 levels in adult idiopathic phosphate diabetes. Calcif Tissue Int 2009; 84(2):ll2-7
    • (2009) Calcif Tissue Int , vol.84 , Issue.2
    • Laroche, M.1    Boyer, J.F.2    Jahafar, H.3
  • 110
    • 85047691059 scopus 로고    scopus 로고
    • FGF-23 in fibrous dysplasia ofbone and its relationship to renal phosphate wasting
    • Riminucci M, Collins MT, Fedarko NS etal. FGF-23 in fibrous dysplasia ofbone and its relationship to renal phosphate wasting. J Clin Invest 2003; ll2(5):683-92
    • (2003) J Clin Invest , vol.112 , Issue.5 , pp. 683-692
    • Riminucci, M.1    Collins, M.T.2    Fedarko, N.S.3
  • 111
    • 27744545673 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease
    • Gutierrez O, Isakova T, Rhee E et al. Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol 2005; l6(7):2205-l5
    • (2005) J Am Soc Nephrol , vol.16 , Issue.7 , pp. 2205-2215
    • Gutierrez, O.1    Isakova, T.2    Rhee, E.3
  • 112
    • 70349113905 scopus 로고    scopus 로고
    • RT-PCR analysis for FGF23 using paraffin sections in the diagnosis of phosphaturic mesenchymal tumors with and without known tumor induced osteomalacia
    • Bahrami A, Weiss SW, Montgomery E et al. RT-PCR analysis for FGF23 using paraffin sections in the diagnosis of phosphaturic mesenchymal tumors with and without known tumor induced osteomalacia. Am J Surg Pathol 2009; 33(9):l348-54
    • (2009) Am J Surg Pathol , vol.33 , Issue.9
    • Bahrami, A.1    Weiss, S.W.2    Montgomery, E.3
  • 113
    • 77956319437 scopus 로고    scopus 로고
    • FGF23 gene expression is upregulated by PTH receptor activation in osteocytes in vitro and in vivo: A parathyroid-bone link influencing the endocrine function of osteocytes
    • Rhee Y. FGF23 gene expression is upregulated by PTH receptor activation in osteocytes in vitro and in vivo: a parathyroid-bone link influencing the endocrine function of osteocytes. J Bone Miner Res 2009; 24(Suppl l)
    • (2009) J Bone Miner Res , vol.24 , Issue.SUPPL. 1
    • Rhee, Y.1
  • 114
    • 67650309019 scopus 로고    scopus 로고
    • Bone modeling and remodeling
    • Seeman E. Bone modeling and remodeling. Crit Rev Eukaryot Gene Expr 2009; l9(3):2l9-33
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , Issue.3 , pp. 219-233
    • Seeman, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.