Real-time imaging reveals endothelium-mediated leukocyte retention in LPS-treated lung microvessels

Microvascular Research

Volumn 83, Issue 3, 2012, Pages 323-331

  Kandasamy, Kathirvel ^a   Sahu, Geetaram ^a   Parthasarathi, Kaushik ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; LIPOPOLYSACCHARIDE; POLYMYXIN B;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; EX VIVO STUDY; FLUORESCENCE IMAGING; IMAGE ANALYSIS; IMMUNOFLUORESCENCE TEST; LEUKOCYTE; LUNG BLOOD VESSEL; LUNG CAPILLARY; LUNG MICROVESSEL; LUNG PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME FLUORESCENCE IMAGING; VENULE;

ANIMALS; CAPILLARIES; DIAGNOSTIC IMAGING; ENDOTHELIUM, VASCULAR; FLUORESCENT DYES; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; L-SELECTIN; LEUKOCYTES; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICROCIRCULATION; MICROSCOPY, FLUORESCENCE; PERFUSION; POLYMYXIN B; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TIME FACTORS;

RATTUS;

EID: 84859517096     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2012.01.006     Document Type: Article

References (36)

1. Andonegui G., Bonder C.S., Green F., Mullaly S.C., Zbytnuik L., Raharjo E., Kubes P. Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J. Clin. Invest. 2003, 111:1011-1020.
2. Aoki T., Suzuki Y., Nishio K., Suzuki K., Miyata A., Iigou Y., Serizawa H., Tsumura H., Ishimura Y., Suematsu M., Yamaguchi K. Role of CD18-ICAM-1 in the entrapment of stimulated leukocytes in alveolar capillaries of perfused rat lungs. Am. J. Physiol. 1997, 273:H2361-H2371.
3. Basit A., Reutershan J., Morris M.A., Solga M., Rose C.E., Ley K. ICAM-1 and LFA-1 play critical roles in LPS-induced neutrophil recruitment into the alveolar space. Am. J. Physiol. Lung Cell. Mol. Physiol. 2006, 291:L200-L207.
4. Burns A.R., Takei F., Doerschuk C.M. Quantitation of ICAM-1 expression in mouse lung during pneumonia. J. Immunol. 1994, 153:3189-3198.
5. Chow J.C., Young D.W., Golenbock D.T., Christ W.J., Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 1999, 274:10689-10692.
6. Doerschuk C.M. Mechanisms of leukocyte sequestration in inflamed lungs. Microcirculation 2001, 8:71-88.
7. Doherty D.E., Downey G.P., Schwab B., Elson E., Worthen G.S. Lipolysaccharide-induced monocyte retention in the lung. Role of monocyte stiffness, actin assembly, and CD18-dependent adherence. J. Immunol. 1994, 153:241-255.
8. Doyle N.A., Bhagwan S.D., Meek B.B., Kutkoski G.J., Steeber D.A., Tedder T.F., Doerschuk C.M. Neutrophil margination, sequestration, and emigration in the lungs of L-selectin-deficient mice. J. Clin. Invest. 1997, 99:526-533.
9. Erickson S.E., Martin G.S., Davis J.L., Matthay M.A., Eisner M.D. Recent trends in acute lung injury mortality: 1996-2005. Crit. Care Med. 2009, 37:1574-1579.
10. Gebb S.A., Graham J.A., Hanger C.C., Godbey P.S., Capen R.L., Doerschuk C.M., Wagner W.W. Sites of leukocyte sequestration in the pulmonary microcirculation. J. Appl. Physiol. 1995, 79:493-497.
11. Grimminger F., Mayer K., Kiss L., Walmrath D., Seeger W. PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 2000, 278:L268-L275.
12. Hattar K., Oppermann S., Ankele C., Weissmann N., Schermuly R.T., Bohle R.M., Moritz R., Krogel B., Seeger W., Grimminger F., et al. c-ANCA-induced neutrophil-mediated lung injury: a model of acute Wegener's granulomatosis. Eur. Respir. J. 2010, 36:187-195.
13. Hu G., Malik A.B., Minshall R.D. Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Crit. Care Med. 2010, 38:194-201.
14. Ichimura H., Parthasarathi K., Issekutz A.C., Bhattacharya J. Pressure-induced leukocyte margination in lung postcapillary venules. Am. J. Physiol. Lung Cell. Mol. Physiol. 2005, 289:L407-L412.
15. Kamochi M., Kamochi F., Kim Y.B., Sawh S., Sanders J.M., Sarembock I., Green S., Young J.S., Ley K., Fu S.M., et al. P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver. Am. J. Physiol. 1999, 277:L310-L319.
16. Kuebler W.M., Borges J., Sckell A., Kuhnle G.E., Bergh K., Messmer K., Goetz A.E. Role of L-selectin in leukocyte sequestration in lung capillaries in a rabbit model of endotoxemia. Am. J. Respir. Crit. Care Med. 2000, 161:36-43.
17. Kuhnle G.E., Kuebler W.M., Groh J., Goetz A.E. Effect of blood flow on the leukocyte-endothelium interaction in pulmonary microvessels. Am. J. Respir. Crit. Care Med. 1995, 152:1221-1228.
18. Kumasaka T., Quinlan W.M., Doyle N.A., Condon T.P., Sligh J., Takei F., Beaudet A., Bennett C.F., Doerschuk C.M. Role of the intercellular adhesion molecule-1 (ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice. J. Clin. Invest. 1996, 97:2362-2369.
19. Ledebur H.C., Parks T.P. Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers. J. Biol. Chem. 1995, 270:933-943.
20. Melamed A., Sorvillo F.J. The burden of sepsis-associated mortality in the United States from 1999 to 2005: an analysis of multiple-cause-of-death data. Crit. Care 2009, 13:R28.
21. Mizgerd J.P., Lupa M.M., Spieker M.S. NF-kappaB p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation. BMC Immunol. 2004, 5:10.
22. Norman K.E., Moore K.L., McEver R.P., Ley K. Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand-1. Blood 1995, 86:4417-4421.
23. Parthasarathi K., Ichimura H., Quadri S., Issekutz A., Bhattacharya J. Mitochondrial reactive oxygen species regulate spatial profile of proinflammatory responses in lung venular capillaries. J. Immunol. 2002, 169:7078-7086.
24. 2+-dependent proinflammatory responses in lung capillaries. J. Clin. Invest. 2006, 116:2193-2200.
25. Ploppa A., Schmidt V., Hientz A., Reutershan J., Haeberle H.A., Nohé B. Mechanisms of leukocyte distribution during sepsis: an experimental study on the interdependence of cell activation, shear stress and endothelial injury. Crit. Care 2010, 14:R201.
26. Poltorak A., He X., Smirnova I., Liu M.Y., Van Huffel C., Du X., Birdwell D., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., Layton B., Beutler B. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in TLR4 gene. Science 1998, 282:2085-2088.
27. 2+ determines the severity of inflammation in mouse lung microvessels. J. Clin. Invest. 2011, 121:1986-1999.
28. Saito H., Lai J., Rogers R., Doerschuk C.M. Mechanical properties of rat bone marrow and circulating neutrophils and their responses to inflammatory mediators. Blood 2002, 99:2207-2213.
29. Sato Y., van Eeden S.F., English D., Hogg J.C. Bacteremic pneumococcal pneumonia: bone marrow release and pulmonary sequestration of neutrophils. Crit. Care Med. 1998, 26:501-509.
30. Sharma A.K., LaPar D.J., Zhao Y., Li L., Lau C.L., Kron I.L., Iwakura Y., Okusa M.D., Laubach V.E. Natural killer T cell-derived IL-17 mediates lung ischemia-reperfusion injury. Am. J. Respir. Crit. Care Med. 2011, 183:1539-1549.
31. Van Putte B.P., Kesecioglu J., Hendriks J.M., Persy V.P., van Marck E., Van Schil P.E., De Broe M.E. Cellular infiltrates and injury evaluation in a rat model of warm pulmonary ischemia-reperfusion. Crit. Care 2005, 9:R1-R8.
32. Wang Q., Doerschuk C.M. The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation. J. Immunol. 2001, 166:6877-6884.
33. Wang Q., Chiang E.T., Lim M., Lai J., Rogers R., Janmey P.A., Shepro D., Doerschuk C.M. Changes in the biomechanical properties of neutrophils and endothelial cells during adhesion. Blood 2001, 97:660-668.
34. Worthen G.S., Schwab B., Elson E.L., Downey G.P. Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries. Science 1989, 245:183-186.
35. Yiming M.T., Parthasarathi K., Issekutz A.C., Bhattacharya S. Sequence of endothelial signaling during lung expansion. Am. J. Respir. Cell Mol. Biol. 2005, 33:549-554.
36. Yoshida K., Kondo R., Wang Q., Doerschuk C.M. Neutrophil cytoskeletal rearrangements during capillary sequestration in bacterial pneumonia in rats. Am. J. Respir. Crit. Care Med. 2006, 174:689-698.