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Volumn 287, Issue 14, 2012, Pages 11556-11565

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; CELL PERIPHERY; CELLULAR LEVELS; CYTOSKELETAL PROTEINS; ERM PROTEINS; MUTATION RESULTS; PATHOPHYSIOLOGICAL; REACTIVE OXYGEN SPECIES; VASCULAR MALFORMATION;

EID: 84859501932     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.320259     Document Type: Article
Times cited : (62)

References (43)
  • 2
    • 27644471154 scopus 로고    scopus 로고
    • Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3
    • Guclu, B., Ozturk, A. K., Pricola, K. L., Bilguvar, K., Shin, D., O'Roak, B. J., and Gunel, M. (2005) Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3. Neurosurgery 57, 1008-1013
    • (2005) Neurosurgery , vol.57 , pp. 1008-1013
    • Guclu, B.1    Ozturk, A.K.2    Pricola, K.L.3    Bilguvar, K.4    Shin, D.5    O'Roak, B.J.6    Gunel, M.7
  • 3
    • 77954926292 scopus 로고    scopus 로고
    • Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity
    • Li, X., Zhang, R., Zhang, H., He, Y., Ji, W., Min, W., and Boggon, T. J. (2010) Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. J. Biol. Chem. 285, 24099-24107
    • (2010) J. Biol. Chem. , vol.285 , pp. 24099-24107
    • Li, X.1    Zhang, R.2    Zhang, H.3    He, Y.4    Ji, W.5    Min, W.6    Boggon, T.J.7
  • 4
    • 77953866538 scopus 로고    scopus 로고
    • Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development
    • He, Y., Zhang, H., Yu, L., Gunel, M., Boggon, T. J., Chen, H., and Min, W. (2010) Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci. Signal. 3, ra26
    • (2010) Sci. Signal. , vol.3
    • He, Y.1    Zhang, H.2    Yu, L.3    Gunel, M.4    Boggon, T.J.5    Chen, H.6    Min, W.7
  • 9
    • 34250330782 scopus 로고    scopus 로고
    • PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway
    • DOI 10.1091/mbc.E06-07-0608
    • Ma, X., Zhao, H., Shan, J., Long, F., Chen, Y., Chen, Y., Zhang, Y., Han, X., and Ma, D. (2007) PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway. Mol. Biol. Cell 18, 1965-1978 (Pubitemid 46911350)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.6 , pp. 1965-1978
    • Ma, X.1    Zhao, H.2    Shan, J.3    Long, F.4    Chen, Y.5    Chen, Y.6    Zhang, Y.7    Han, X.8    Ma, D.9
  • 10
    • 34948833449 scopus 로고    scopus 로고
    • CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations
    • DOI 10.1007/s10048-007-0098-9
    • Voss, K., Stahl, S., Schleider, E., Ullrich, S., Nickel, J., Mueller, T. D., and Felbor, U. (2007) CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations. Neurogenetics 8, 249-256 (Pubitemid 47624455)
    • (2007) Neurogenetics , vol.8 , Issue.4 , pp. 249-256
    • Voss, K.1    Stahl, S.2    Schleider, E.3    Ullrich, S.4    Nickel, J.5    Mueller, T.D.6    Felbor, U.7
  • 11
    • 77951194603 scopus 로고    scopus 로고
    • CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation
    • Fidalgo, M., Fraile, M., Pires, A., Force, T., Pombo, C., and Zalvide, J. (2010) CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation. J. Cell Sci. 123, 1274-1284
    • (2010) J. Cell Sci. , vol.123 , pp. 1274-1284
    • Fidalgo, M.1    Fraile, M.2    Pires, A.3    Force, T.4    Pombo, C.5    Zalvide, J.6
  • 15
    • 43049155951 scopus 로고    scopus 로고
    • Biosignaling of mammalian Ste20-related kinases
    • Ling, P., Lu, T. J., Yuan, C. J., and Lai, M. D. (2008) Biosignaling of mammalian Ste20-related kinases. Cell. Signal. 20, 1237-1247
    • (2008) Cell. Signal. , vol.20 , pp. 1237-1247
    • Ling, P.1    Lu, T.J.2    Yuan, C.J.3    Lai, M.D.4
  • 16
    • 0035341895 scopus 로고    scopus 로고
    • The Ste20 group kinases as regulators of MAP kinase cascades
    • DOI 10.1016/S0962-8924(01)01980-8, PII S0962892401019808
    • Dan, I., Watanabe, N. M., and Kusumi, A. (2001) The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol. 11, 220-230 (Pubitemid 32367879)
    • (2001) Trends in Cell Biology , vol.11 , Issue.5 , pp. 220-230
    • Dan, I.1    Watanabe, N.M.2    Kusumi, A.3
  • 19
    • 47049088906 scopus 로고    scopus 로고
    • SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death
    • Nogueira, E., Fidalgo, M., Molnar, A., Kyriakis, J., Force, T., Zalvide, J., and Pombo, C. M. (2008) SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death. J. Biol. Chem. 283, 16248-16258
    • (2008) J. Biol. Chem. , vol.283 , pp. 16248-16258
    • Nogueira, E.1    Fidalgo, M.2    Molnar, A.3    Kyriakis, J.4    Force, T.5    Zalvide, J.6    Pombo, C.M.7
  • 20
    • 67651215903 scopus 로고    scopus 로고
    • Serine 58 of 14-3-3ζ is a molecular switch regulating ASK1 and oxidant stress-induced cell death
    • Zhou, J., Shao, Z., Kerkela, R., Ichijo, H., Muslin, A. J., Pombo, C., and Force, T. (2009) Serine 58 of 14-3-3ζ is a molecular switch regulating ASK1 and oxidant stress-induced cell death. Mol. Cell. Biol. 29, 4167-4176
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 4167-4176
    • Zhou, J.1    Shao, Z.2    Kerkela, R.3    Ichijo, H.4    Muslin, A.J.5    Pombo, C.6    Force, T.7
  • 22
    • 1842613600 scopus 로고    scopus 로고
    • YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3ζ
    • DOI 10.1083/jcb.200310061
    • Preisinger, C., Short, B., De Corte, V., Bruyneel, E., Haas, A., Kopajtich, R., Gettemans, J., and Barr, F. A. (2004) YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3ζ. J. Cell Biol. 164, 1009-1020 (Pubitemid 38429127)
    • (2004) Journal of Cell Biology , vol.164 , Issue.7 , pp. 1009-1020
    • Preisinger, C.1    Short, B.2    De Corte, V.3    Bruyneel, E.4    Haas, A.5    Kopajtich, R.6    Gettemans, J.7    Barr, F.A.8
  • 25
    • 65249182536 scopus 로고    scopus 로고
    • Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3
    • Chen, L., Tanriover, G., Yano, H., Friedlander, R., Louvi, A., and Gunel, M. (2009) Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3. Stroke 40, 1474-1481
    • (2009) Stroke , vol.40 , pp. 1474-1481
    • Chen, L.1    Tanriover, G.2    Yano, H.3    Friedlander, R.4    Louvi, A.5    Gunel, M.6
  • 26
    • 79951544995 scopus 로고    scopus 로고
    • Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3
    • Schleider, E., Stahl, S., Wustehube, J., Walter, U., Fischer, A., and Felbor, U. (2010) Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3. Neurogenetics 12, 83-86
    • (2010) Neurogenetics , vol.12 , pp. 83-86
    • Schleider, E.1    Stahl, S.2    Wustehube, J.3    Walter, U.4    Fischer, A.5    Felbor, U.6
  • 27
    • 80051789017 scopus 로고    scopus 로고
    • In vitro characterization of the angiogenic phenotype and genotype of the endothelia derived from sporadic cerebral cavernous malformations
    • Zhu, Y., Wu, Q., Xu, J. F., Miller, D., Sandalcioglu, I. E., Zhang, J. M., and Sure, U. (2011) In vitro characterization of the angiogenic phenotype and genotype of the endothelia derived from sporadic cerebral cavernous malformations. Neurosurgery 69, 722-731
    • (2011) Neurosurgery , vol.69 , pp. 722-731
    • Zhu, Y.1    Wu, Q.2    Xu, J.F.3    Miller, D.4    Sandalcioglu, I.E.5    Zhang, J.M.6    Sure, U.7
  • 28
    • 0029814060 scopus 로고    scopus 로고
    • Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway
    • Pombo, C. M., Bonventre, J. V., Molnar, A., Kyriakis, J., and Force, T. (1996) Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway. EMBO J. 15, 4537-4546 (Pubitemid 26294572)
    • (1996) EMBO Journal , vol.15 , Issue.17 , pp. 4537-4546
    • Pombo, C.M.1    Bonventre, J.V.2    Molnar, A.3    Kyriakis, J.4    Force, T.5
  • 29
    • 33846018602 scopus 로고    scopus 로고
    • Cell death by necrosis: towards a molecular definition
    • DOI 10.1016/j.tibs.2006.11.001, PII S0968000406003185
    • Golstein, P., and Kroemer, G. (2007) Cell death by necrosis. Towards a molecular definition. Trends Biochem. Sci. 32, 37-43 (Pubitemid 46043552)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.1 , pp. 37-43
    • Golstein, P.1    Kroemer, G.2
  • 30
    • 0028500118 scopus 로고
    • Dysfunction of mouse liver mitochondria induced by 2, 2'-azobis-(2-amidinopropane) dihydrochloride, a radical initiator, in vitro and in vivo
    • Kanno, T., Utsumi, T., Ide, A., Takehara, Y., Saibara, T., Akiyama, J., Yoshioka, T., and Utsumi, K. (1994) Dysfunction of mouse liver mitochondria induced by 2,2′-azobis-(2-amidinopropane) dihydrochloride, a radical initiator, in vitro and in vivo. Free Radic. Res. 21, 223-234 (Pubitemid 2137691)
    • (1994) Free Radical Research , vol.21 , Issue.4 , pp. 223-234
    • Kanno, T.1    Utsumi, T.2    Ide, A.3    Takehara, Y.4    Saibara, T.5    Akiyama, J.6    Yoshioka, T.7    Utsumi, K.8
  • 31
    • 0034631843 scopus 로고    scopus 로고
    • Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane
    • DOI 10.1083/jcb.150.1.193
    • Gautreau, A., Louvard, D., and Arpin, M. (2000) Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J. Cell Biol. 150, 193-203 (Pubitemid 30480237)
    • (2000) Journal of Cell Biology , vol.150 , Issue.1 , pp. 193-203
    • Gautreau, A.1    Louvard, D.2    Arpin, M.3
  • 33
    • 0032498528 scopus 로고    scopus 로고
    • Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
    • DOI 10.1083/jcb.140.3.647
    • Matsui, T., Maeda, M., Doi, Y., Yonemura, S., Amano, M., Kaibuchi, K., Tsukita, S., and Tsukita, S. (1998) Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J. Cell Biol. 140, 647-657 (Pubitemid 28134067)
    • (1998) Journal of Cell Biology , vol.140 , Issue.3 , pp. 647-657
    • Matsui, T.1    Maeda, M.2    Doi, Y.3    Yonemura, S.4    Amano, M.5    Kaibuchi, K.6    Tsukita, S.7    Tsukita, S.8
  • 34
    • 0032567361 scopus 로고    scopus 로고
    • Phosphorylation of moesin by Rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures
    • DOI 10.1074/jbc.273.52.34663
    • Oshiro, N., Fukata, Y., and Kaibuchi, K. (1998) Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. J. Biol. Chem. 273, 34663-34666 (Pubitemid 29028150)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.52 , pp. 34663-34666
    • Oshiro, N.1    Fukata, Y.2    Kaibuchi, K.3
  • 35
    • 0034282766 scopus 로고    scopus 로고
    • Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes
    • Tran Quang, C., Gautreau, A., Arpin, M., and Treisman, R. (2000) Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes. EMBO J. 19, 4565-4576
    • (2000) EMBO J. , vol.19 , pp. 4565-4576
    • Tran Quang, C.1    Gautreau, A.2    Arpin, M.3    Treisman, R.4
  • 38
    • 4444258587 scopus 로고    scopus 로고
    • Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth
    • DOI 10.1101/gad.303304
    • Hipfner, D. R., Keller, N., and Cohen, S. M. (2004) Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth. Genes Dev. 18, 2243-2248 (Pubitemid 39209572)
    • (2004) Genes and Development , vol.18 , Issue.18 , pp. 2243-2248
    • Hipfner, D.R.1    Keller, N.2    Cohen, S.M.3
  • 39
    • 0030703639 scopus 로고    scopus 로고
    • 2+]
    • DOI 10.1074/jbc.272.46.29372
    • Pombo, C. M., Tsujita, T., Kyriakis, J. M., Bonventre, J. V., and Force, T. (1997) Activation of the Ste20-like oxidant stress response kinase-1 during the initial stages of chemical anoxia-induced necrotic cell death. Requirement for dual inputs of oxidant stress and increased cytosolic [Ca2+]. J. Biol. Chem. 272, 29372-29379 (Pubitemid 27498232)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.46 , pp. 29372-29379
    • Pombo, C.M.1    Tsujita, T.2    Kyriakis, J.M.3    Bonventre, J.V.4    Force, T.5
  • 42
    • 0031471375 scopus 로고    scopus 로고
    • Ezrin: A protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures
    • Bretscher, A., Reczek, D., and Berryman, M. (1997) Ezrin. A protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures. J. Cell Sci. 110, 3011-3018 (Pubitemid 28026432)
    • (1997) Journal of Cell Science , vol.110 , Issue.24 , pp. 3011-3018
    • Bretscher, A.1    Reczek, D.2    Berryman, M.3
  • 43
    • 34247336193 scopus 로고    scopus 로고
    • Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells
    • DOI 10.1152/ajpcell.00375.2006
    • Tamma, G., Procino, G., Svelto, M., and Valenti, G. (2007) Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells. Am. J. Physiol. Cell. Physiol. 292, C1476-84 (Pubitemid 46631738)
    • (2007) American Journal of Physiology - Cell Physiology , vol.292 , Issue.4
    • Tamma, G.1    Procino, G.2    Svelto, M.3    Valenti, G.4


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