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Volumn 23, Issue 4, 2012, Pages 815-822

Intensified chemotherapy with stem-cell rescue in germ-cell tumors

Author keywords

Autologous stem cell transplantation; Germ cell tumors; High dose chemotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; EPIRUBICIN; ETOPOSIDE; IFOSFAMIDE; PACLITAXEL; THIOTEPA; VINBLASTINE;

EID: 84859492667     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdr403     Document Type: Review
Times cited : (23)

References (56)
  • 1
    • 0031408767 scopus 로고    scopus 로고
    • Testicular cancer: an oncological success story
    • Einhorn LH. Testicular cancer: an oncological success story. Clin Cancer Res 1997; 3: 2630-2632.
    • (1997) Clin Cancer Res , vol.3 , pp. 2630-2632
    • Einhorn, L.H.1
  • 2
    • 0030857028 scopus 로고    scopus 로고
    • Testicular germ-cell cancer
    • Bosl GJ, Motzer RJ. Testicular germ-cell cancer. N Engl J Med 1997; 337: 242-253.
    • (1997) N Engl J Med , vol.337 , pp. 242-253
    • Bosl, G.J.1    Motzer, R.J.2
  • 3
    • 0023195303 scopus 로고
    • Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide
    • Williams SD, Birch R, Einhorn LH et al. Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide. N Engl J Med 1987; 316: 1435-1440.
    • (1987) N Engl J Med , vol.316 , pp. 1435-1440
    • Williams, S.D.1    Birch, R.2    Einhorn, L.H.3
  • 4
    • 0344734200 scopus 로고    scopus 로고
    • Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor
    • Loehrer PJ Sr, Gonin R, Nichols CR et al. Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor. J Clin Oncol 1998; 16: 2500-2504.
    • (1998) J Clin Oncol , vol.16 , pp. 2500-2504
    • Loehrer Sr., P.J.1    Gonin, R.2    Nichols, C.R.3
  • 5
    • 0030814035 scopus 로고    scopus 로고
    • Ifosfamide and cisplatin-containing chemotherapy as first-line salvage therapy in germ-cell tumors: response and survival
    • McCaffrey JA, Mazumdar M, Bajorin DF et al. Ifosfamide and cisplatin-containing chemotherapy as first-line salvage therapy in germ-cell tumors: response and survival. J Clin Oncol 1997; 15: 2559-2563.
    • (1997) J Clin Oncol , vol.15 , pp. 2559-2563
    • McCaffrey, J.A.1    Mazumdar, M.2    Bajorin, D.F.3
  • 6
    • 0024995401 scopus 로고
    • Dose intensity versus total dose of chemotherapy: an experimental basis
    • De Vita VT, Hellman S, Rosemberg SA (eds). Philadelphia, PA: Lippincott
    • Skipper HE. Dose intensity versus total dose of chemotherapy: an experimental basis. In De Vita VT, Hellman S, Rosemberg SA (eds). Important Advances in Oncology. Philadelphia, PA: Lippincott 1990; 43-64.
    • (1990) Important Advances in Oncology , pp. 43-64
    • Skipper, H.E.1
  • 7
    • 0024439774 scopus 로고
    • Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor
    • Siena S, Bregni M, Brando B et al. Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor. Blood 1989; 74: 1905-1914.
    • (1989) Blood , vol.74 , pp. 1905-1914
    • Siena, S.1    Bregni, M.2    Brando, B.3
  • 8
    • 9044236159 scopus 로고    scopus 로고
    • Randomized trial of filgrastim-mobilized peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients
    • Schmitz N, Linch DC, Dreger P et al. Randomized trial of filgrastim-mobilized peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients. Lancet 1996; 347: 353-357.
    • (1996) Lancet , vol.347 , pp. 353-357
    • Schmitz, N.1    Linch, D.C.2    Dreger, P.3
  • 9
    • 0034097402 scopus 로고    scopus 로고
    • Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy
    • Siena S, Schiavo R, Pedrazzoli P, Carlo-Stella C. Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy. J Clin Oncol 2000; 18: 1360-1377.
    • (2000) J Clin Oncol , vol.18 , pp. 1360-1377
    • Siena, S.1    Schiavo, R.2    Pedrazzoli, P.3    Carlo-Stella, C.4
  • 10
    • 35348958398 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous hematopoietic stem cell support for solid tumors in adults
    • Pedrazzoli P, Rosti G, Secondino S et al. High-dose chemotherapy with autologous hematopoietic stem cell support for solid tumors in adults. Semin Hematol 2007; 44: 286-295.
    • (2007) Semin Hematol , vol.44 , pp. 286-295
    • Pedrazzoli, P.1    Rosti, G.2    Secondino, S.3
  • 11
    • 0031037241 scopus 로고    scopus 로고
    • International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers
    • International Germ-Cell Cancer Collaborative Group
    • International Germ-Cell Cancer Collaborative Group. International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group. J Clin Oncol 1997; 15: 594-603.
    • (1997) International Germ Cell Cancer Collaborative Group. J Clin Oncol , vol.15 , pp. 594-603
  • 12
    • 0027489607 scopus 로고
    • Phase II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation in first-line therapy for patients with poor-risk germ cell tumors
    • Motzer RJ, Mazumdar M, Gulati SC et al. Phase II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation in first-line therapy for patients with poor-risk germ cell tumors. J Natl Cancer Inst 1993; 85: 1828-1835.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1828-1835
    • Motzer, R.J.1    Mazumdar, M.2    Gulati, S.C.3
  • 13
    • 0030804929 scopus 로고    scopus 로고
    • High-dose carboplatin, etoposide, and cyclophosphamide with autologous bone marrow transplantation in first-line therapy for patients with poor-risk germ cell tumors
    • Motzer RJ, Mazumdar M, Bajorin DF et al. High-dose carboplatin, etoposide, and cyclophosphamide with autologous bone marrow transplantation in first-line therapy for patients with poor-risk germ cell tumors. J Clin Oncol 1997; 15: 2546-2552.
    • (1997) J Clin Oncol , vol.15 , pp. 2546-2552
    • Motzer, R.J.1    Mazumdar, M.2    Bajorin, D.F.3
  • 14
    • 0032703762 scopus 로고    scopus 로고
    • First-line high-dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: a multivariate and matched-pair analysis
    • Bokemeyer C, Kollmannsberger C, Meisner C et al. First-line high-dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: a multivariate and matched-pair analysis. J Clin Oncol 1999; 17: 3450-3456.
    • (1999) J Clin Oncol , vol.17 , pp. 3450-3456
    • Bokemeyer, C.1    Kollmannsberger, C.2    Meisner, C.3
  • 15
    • 0022576065 scopus 로고
    • Prognostic factors for favourable outcome in disseminated germ cell tumors
    • Birch R, Williams S, Cone A et al. Prognostic factors for favourable outcome in disseminated germ cell tumors. J Clin Oncol 1986; 4: 400-407.
    • (1986) J Clin Oncol , vol.4 , pp. 400-407
    • Birch, R.1    Williams, S.2    Cone, A.3
  • 16
    • 0642347620 scopus 로고    scopus 로고
    • Long-term results of first-line sequential high dose VIP chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group
    • Schmoll HJ, Kollmannsberger C, Metzner B et al. Long-term results of first-line sequential high dose VIP chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group. J Clin Oncol 2003; 21: 4083-4091.
    • (2003) J Clin Oncol , vol.21 , pp. 4083-4091
    • Schmoll, H.J.1    Kollmannsberger, C.2    Metzner, B.3
  • 18
    • 34548405549 scopus 로고    scopus 로고
    • Paclitaxel plus ifosfamide followed by high-dose carboplatin plus etoposide in previously treated germ cell tumors
    • Kondagunta GV, Bacik J, Sheinfeld J et al. Paclitaxel plus ifosfamide followed by high-dose carboplatin plus etoposide in previously treated germ cell tumors. J Clin Oncol 2007; 25: 85-90.
    • (2007) J Clin Oncol , vol.25 , pp. 85-90
    • Kondagunta, G.V.1    Bacik, J.2    Sheinfeld, J.3
  • 19
    • 0034018301 scopus 로고    scopus 로고
    • Sequential dose-intensive paclitaxel, ifosfamide, carboplatin, and etoposide salvage therapy for germ cell tumor patients
    • Motzer RJ, Mazumdar M, Sheinfeld J et al. Sequential dose-intensive paclitaxel, ifosfamide, carboplatin, and etoposide salvage therapy for germ cell tumor patients. J Clin Oncol 2000; 8: 1173-1180.
    • (2000) J Clin Oncol , vol.8 , pp. 1173-1180
    • Motzer, R.J.1    Mazumdar, M.2    Sheinfeld, J.3
  • 20
    • 37649025685 scopus 로고    scopus 로고
    • Phase I/II study of sequential doseintensified ifosfamide, cisplatin, and etoposide plus paclitaxel as induction chemotherapy for poor prognosis germ cell tumors by the German Testicular Cancer Study Group
    • Hartmann JT, Gauler T, Metzner B et al. Phase I/II study of sequential doseintensified ifosfamide, cisplatin, and etoposide plus paclitaxel as induction chemotherapy for poor prognosis germ cell tumors by the German Testicular Cancer Study Group. J Clin Oncol 2007; 25: 5742-5747.
    • (2007) J Clin Oncol , vol.25 , pp. 5742-5747
    • Hartmann, J.T.1    Gauler, T.2    Metzner, B.3
  • 21
    • 33846917709 scopus 로고    scopus 로고
    • Phase III randomized trial of conventional-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors
    • Motzer RJ, Nichols CJ, Margolin KA et al. Phase III randomized trial of conventional-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors. J Clin Oncol 2007; 25: 247-256.
    • (2007) J Clin Oncol , vol.25 , pp. 247-256
    • Motzer, R.J.1    Nichols, C.J.2    Margolin, K.A.3
  • 22
    • 84859506313 scopus 로고    scopus 로고
    • High-dose sequential chemotherapy versus conventional-dose chemotherapy as first-line treatment for advanced poor prognosis germ-cell tumors: a multicenter phase III Italian trial
    • Di Nicola M, Necchi A, Nicolai N et al. High-dose sequential chemotherapy versus conventional-dose chemotherapy as first-line treatment for advanced poor prognosis germ-cell tumors: a multicenter phase III Italian trial. Ann Oncol 2009; 20 (Suppl 8): viii3-viii4.
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 8
    • Di Nicola, M.1    Necchi, A.2    Nicolai, N.3
  • 23
    • 78650418112 scopus 로고    scopus 로고
    • A randomized phase III study comparing standard dose BEP with sequential high-dose cisplatin, etoposide, ifosfamide (VIP) plus stem cell support in males with poor prognosis germ cell cancer (GCC): an intergroup study of EORTC, GTCSG, and Grupo Germinal (EORTC 30974)
    • (Abstr 4512)
    • Daugaard G, Skoneczna IA, Aass N et al. A randomized phase III study comparing standard dose BEP with sequential high-dose cisplatin, etoposide, ifosfamide (VIP) plus stem cell support in males with poor prognosis germ cell cancer (GCC): an intergroup study of EORTC, GTCSG, and Grupo Germinal (EORTC 30974). Proc Am Soc Clin Oncol 2010; 28 (Suppl): 15s (Abstr 4512).
    • (2010) Proc Am Soc Clin Oncol , vol.28 , Issue.SUPPL.
    • Daugaard, G.1    Skoneczna, I.A.2    Aass, N.3
  • 24
    • 27244441799 scopus 로고    scopus 로고
    • Combination of paclitaxel, ifosfamide, and cisplatin is an effective second-line therapy for patients with relapsed testicular germ cell tumors
    • Kondagunta GV, Bacik J, Donadio A et al. Combination of paclitaxel, ifosfamide, and cisplatin is an effective second-line therapy for patients with relapsed testicular germ cell tumors. J Clin Oncol 2005; 23: 6549-6555.
    • (2005) J Clin Oncol , vol.23 , pp. 6549-6555
    • Kondagunta, G.V.1    Bacik, J.2    Donadio, A.3
  • 25
    • 0021248775 scopus 로고
    • Cyclophosphamide and VP16-213 with autologous bone marrow transplantation: a dose escalation study
    • Postmus PE, De Vries EG, De Vries-Hospars HG et al. Cyclophosphamide and VP16-213 with autologous bone marrow transplantation: a dose escalation study. Eur J Cancer Clin Oncol 1984; 20: 777-782.
    • (1984) Eur J Cancer Clin Oncol , vol.20 , pp. 777-782
    • Postmus, P.E.1    De Vries, E.G.2    De Vries-Hospars, H.G.3
  • 26
    • 0023923396 scopus 로고
    • Salvage chemotherapy in refractory germ cell tumors with etoposide (VP-16) plus ifosfamide plus high-dose cisplatin. A VihP regimen
    • Ghosn M, Droz JP, Theodore C et al. Salvage chemotherapy in refractory germ cell tumors with etoposide (VP-16) plus ifosfamide plus high-dose cisplatin. A VihP regimen. Cancer 1988; 62: 24-27.
    • (1988) Cancer , vol.62 , pp. 24-27
    • Ghosn, M.1    Droz, J.P.2    Theodore, C.3
  • 27
    • 0024338525 scopus 로고
    • Dose-intensive chemotherapy in refractory germ cell cancer-a phase 1/2 trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation
    • Nichols CR, Tricot G, Williams SD et al. Dose-intensive chemotherapy in refractory germ cell cancer-a phase 1/2 trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation. J Clin Oncol 1989; 7: 932-939.
    • (1989) J Clin Oncol , vol.7 , pp. 932-939
    • Nichols, C.R.1    Tricot, G.2    Williams, S.D.3
  • 28
    • 0026729352 scopus 로고
    • Long-term outcome of patients with relapsed and refractory germ cell tumors treated with high-dose chemotherapy and autologous bone marrow rescue
    • Brown ER, Nichols CR, Kneebone P et al. Long-term outcome of patients with relapsed and refractory germ cell tumors treated with high-dose chemotherapy and autologous bone marrow rescue. Ann Intern Med 1992; 117: 124-128.
    • (1992) Ann Intern Med , vol.117 , pp. 124-128
    • Brown, E.R.1    Nichols, C.R.2    Kneebone, P.3
  • 29
    • 0026580199 scopus 로고
    • High-dose chemotherapy with autologous bone marrow rescue for patients with refractory germ cell tumors. Early intervention is better tolerated
    • Motzer RJ, Gulati SC, Crown JP et al. High-dose chemotherapy with autologous bone marrow rescue for patients with refractory germ cell tumors. Early intervention is better tolerated. Cancer 1992; 69: 550-556.
    • (1992) Cancer , vol.69 , pp. 550-556
    • Motzer, R.J.1    Gulati, S.C.2    Crown, J.P.3
  • 30
    • 0028229053 scopus 로고
    • High-dose treatment with carboplatin, etoposide, and ifosfamide followed by autologous stemcell transplantation in relapsed or refractory germ cell cancer: a phase I/II study. The German Testicular Cancer Cooperative Study Group
    • Siegert W, Beyer J, Strohscheer I et al. High-dose treatment with carboplatin, etoposide, and ifosfamide followed by autologous stemcell transplantation in relapsed or refractory germ cell cancer: a phase I/II study. The German Testicular Cancer Cooperative Study Group. J Clin Oncol 1994; 12: 1223-1231.
    • (1994) J Clin Oncol , vol.12 , pp. 1223-1231
    • Siegert, W.1    Beyer, J.2    Strohscheer, I.3
  • 31
    • 10144262544 scopus 로고    scopus 로고
    • High-dose chemotherapy as salvage treatment in germ cell tumors: a multivariate analysis of prognostic variables
    • Beyer J, Kramar A, Mandanas R et al. High-dose chemotherapy as salvage treatment in germ cell tumors: a multivariate analysis of prognostic variables. J Clin Oncol 1996; 14: 2638-2645.
    • (1996) J Clin Oncol , vol.14 , pp. 2638-2645
    • Beyer, J.1    Kramar, A.2    Mandanas, R.3
  • 32
    • 0035148199 scopus 로고    scopus 로고
    • Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer
    • Rick O, Bokemeyer C, Beyer J et al. Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer. J Clin Oncol 2001; 19: 81-88.
    • (2001) J Clin Oncol , vol.19 , pp. 81-88
    • Rick, O.1    Bokemeyer, C.2    Beyer, J.3
  • 33
    • 0034306291 scopus 로고    scopus 로고
    • High dose chemotherapy as initial salvage chemotherapy in patients with relapsed testicular cancer
    • Bhatia S, Abonour R, Porcu P et al. High dose chemotherapy as initial salvage chemotherapy in patients with relapsed testicular cancer. J Clin Oncol 2000; 18: 3346-3351.
    • (2000) J Clin Oncol , vol.18 , pp. 3346-3351
    • Bhatia, S.1    Abonour, R.2    Porcu, P.3
  • 34
    • 0029978783 scopus 로고    scopus 로고
    • Feasibility of multiple courses of high dose cyclophosphamide, thiotepa and carboplatin for breast cancer or germ cell cancer
    • Rodenhuis S, Westermann A, Holtkamps MJ et al. Feasibility of multiple courses of high dose cyclophosphamide, thiotepa and carboplatin for breast cancer or germ cell cancer. J Clin Oncol 1996; 14: 1473-1483.
    • (1996) J Clin Oncol , vol.14 , pp. 1473-1483
    • Rodenhuis, S.1    Westermann, A.2    Holtkamps, M.J.3
  • 35
    • 0036242756 scopus 로고    scopus 로고
    • High-dose versus conventional-dose chemotherapy as first-salvage treatment in patients with non-seminomatous germ-cell tumors: a matched-pair analysis
    • Beyer J, Stenning S, Gerl A et al. High-dose versus conventional-dose chemotherapy as first-salvage treatment in patients with non-seminomatous germ-cell tumors: a matched-pair analysis. Ann Oncol 2002; 13: 599-605.
    • (2002) Ann Oncol , vol.13 , pp. 599-605
    • Beyer, J.1    Stenning, S.2    Gerl, A.3
  • 36
    • 34547200072 scopus 로고    scopus 로고
    • High-dose chemotherapy and stem cell rescue for metastatic germ-cell tumors
    • Einhorn LH, Williams SD, Chamness BA et al. High-dose chemotherapy and stem cell rescue for metastatic germ-cell tumors. N Engl J Med 2007; 357: 340-348.
    • (2007) N Engl J Med , vol.357 , pp. 340-348
    • Einhorn, L.H.1    Williams, S.D.2    Chamness, B.A.3
  • 37
    • 77950466810 scopus 로고    scopus 로고
    • TI-CE high-dose chemotherapy for patients with previously treated germ cell tumors: results and prognostic factor analysis
    • Feldman DR, Sheinfeld J, Bajorin DF et al. TI-CE high-dose chemotherapy for patients with previously treated germ cell tumors: results and prognostic factor analysis. J Clin Oncol 2010; 28: 1706-1713.
    • (2010) J Clin Oncol , vol.28 , pp. 1706-1713
    • Feldman, D.R.1    Sheinfeld, J.2    Bajorin, D.F.3
  • 38
    • 25144455744 scopus 로고    scopus 로고
    • A randomised trial of high-dose chemotherapy in the salvage treatment of patients failing first-line platinum chemotherapy for advanced germ cell tumours
    • Pico JL, Rosti G, Kamar A et al. A randomised trial of high-dose chemotherapy in the salvage treatment of patients failing first-line platinum chemotherapy for advanced germ cell tumours. Ann Oncol 2005; 16: 1152-1159.
    • (2005) Ann Oncol , vol.16 , pp. 1152-1159
    • Pico, J.L.1    Rosti, G.2    Kamar, A.3
  • 39
    • 34447568382 scopus 로고    scopus 로고
    • Single versus sequential highdose chemotherapy in patients with relapsed or refractory germ-cell tumors: a prospective randomized multicentre trial of the German Testicular Cancer Study Group
    • Lorch A, Kollmannsberger C, Hartmann JT et al. Single versus sequential highdose chemotherapy in patients with relapsed or refractory germ-cell tumors: a prospective randomized multicentre trial of the German Testicular Cancer Study Group. J Clin Oncol 2007; 25: 2778-2784.
    • (2007) J Clin Oncol , vol.25 , pp. 2778-2784
    • Lorch, A.1    Kollmannsberger, C.2    Hartmann, J.T.3
  • 40
    • 84859515751 scopus 로고    scopus 로고
    • Superior survival after sequential high-dose chemotherapy (HDCT) as compared to single HDCT in patients with relapsed or refractory germ cell tumors (GCT): six-year long-term follow-up of a prospective, randomized phase II trial
    • (Abstr 4507)
    • Lorch A, Kleinhans A, Kramar A et al. Superior survival after sequential high-dose chemotherapy (HDCT) as compared to single HDCT in patients with relapsed or refractory germ cell tumors (GCT): six-year long-term follow-up of a prospective, randomized phase II trial. Proc Am Soc Clin Oncol 2011; 29 (Suppl): 15 (Abstr 4507).
    • (2011) Proc Am Soc Clin Oncol , vol.29 , Issue.SUPPL. , pp. 15
    • Lorch, A.1    Kleinhans, A.2    Kramar, A.3
  • 41
    • 0022600727 scopus 로고
    • The Norton-Simon hypothesis revisited
    • Norton L, Simon R. The Norton-Simon hypothesis revisited. Cancer Treat Rep 1986; 70: 163-169.
    • (1986) Cancer Treat Rep , vol.70 , pp. 163-169
    • Norton, L.1    Simon, R.2
  • 42
    • 84878708632 scopus 로고    scopus 로고
    • Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy
    • The International Prognostic Factors Study Group
    • The International Prognostic Factors Study Group. Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy. J Clin Oncol 2010; 28: 4906-4911.
    • (2010) J Clin Oncol , vol.28 , pp. 4906-4911
  • 43
    • 79957955963 scopus 로고    scopus 로고
    • Conventional-dose versus high-dose chemotherapy as first salvage treatment in male patients with metastatic germ cell tumors: evidence from a large international database
    • Lorch A, Bascoul-Mollevi C, Kramar A et al. Conventional-dose versus high-dose chemotherapy as first salvage treatment in male patients with metastatic germ cell tumors: evidence from a large international database. J Clin Oncol 2011; 29 (16): 2178-2184.
    • (2011) J Clin Oncol , vol.29 , Issue.16 , pp. 2178-2184
    • Lorch, A.1    Bascoul-Mollevi, C.2    Kramar, A.3
  • 44
    • 84859483276 scopus 로고    scopus 로고
    • High-dose chemotherapy (HDCT) and autologous stem cell transplantation in relapsed germ cell tumors: do we need a randomized study
    • Pedrazzoli P, De Giorgi U, Bregni M. High-dose chemotherapy (HDCT) and autologous stem cell transplantation in relapsed germ cell tumors: do we need a randomized study? Bone Marrow Transplant 2010; 45 (Suppl 2): S30.
    • (2010) Bone Marrow Transplant , vol.45 , Issue.SUPPL. 2
    • Pedrazzoli, P.1    De Giorgi, U.2    Bregni, M.3
  • 45
    • 0029034642 scopus 로고
    • Salvage therapy of germ cell tumors
    • Horwich A. Salvage therapy of germ cell tumors. Br J Cancer 1995; 71: 901-903.
    • (1995) Br J Cancer , vol.71 , pp. 901-903
    • Horwich, A.1
  • 46
    • 20144388986 scopus 로고    scopus 로고
    • Sequential high-dose chemotherapy protocol for relapsed poor prognosis germ cell tumors combining two mobilization and cytoreductive treatments followed by three high-dose chemotherapy regimens supported by autologous stem cell transplantation. Results of the phase II multicentric TAXIF trial
    • Lotz JP, Bui B, Gomez F et al. Sequential high-dose chemotherapy protocol for relapsed poor prognosis germ cell tumors combining two mobilization and cytoreductive treatments followed by three high-dose chemotherapy regimens supported by autologous stem cell transplantation. Results of the phase II multicentric TAXIF trial. Ann Oncol 2005; 16: 411-418.
    • (2005) Ann Oncol , vol.16 , pp. 411-418
    • Lotz, J.P.1    Bui, B.2    Gomez, F.3
  • 47
    • 0642378134 scopus 로고    scopus 로고
    • Long-term survival after high-dose salvage chemotherapy for germ cell malignancies with adverse prognostic variables
    • Vaena DA, Abonour R, Einhorn LH. Long-term survival after high-dose salvage chemotherapy for germ cell malignancies with adverse prognostic variables. J Clin Oncol 2003; 21: 4100-4104.
    • (2003) J Clin Oncol , vol.21 , pp. 4100-4104
    • Vaena, D.A.1    Abonour, R.2    Einhorn, L.H.3
  • 48
    • 77951970473 scopus 로고    scopus 로고
    • High-dose chemotherapy (HDCT) as second-salvage treatment in patients with multiple relapsed or refractory germcell tumors
    • Lorch A, Neubauer A, Hackenthal M et al. High-dose chemotherapy (HDCT) as second-salvage treatment in patients with multiple relapsed or refractory germcell tumors. Ann Oncol 2010; 21: 820-825.
    • (2010) Ann Oncol , vol.21 , pp. 820-825
    • Lorch, A.1    Neubauer, A.2    Hackenthal, M.3
  • 49
    • 0036434657 scopus 로고    scopus 로고
    • Extragonadal germ cell tumors
    • Schmoll HJ. Extragonadal germ cell tumors. Ann Oncol 2002; 13: 265-272.
    • (2002) Ann Oncol , vol.13 , pp. 265-272
    • Schmoll, H.J.1
  • 50
    • 0036533845 scopus 로고    scopus 로고
    • Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis
    • Bokemeyer C, Nichols CR, Droz JP et al. Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis. J Clin Oncol 2002; 20: 1864-1873.
    • (2002) J Clin Oncol , vol.20 , pp. 1864-1873
    • Bokemeyer, C.1    Nichols, C.R.2    Droz, J.P.3
  • 51
    • 0042346023 scopus 로고    scopus 로고
    • First-line sequential high-dose VIP chemotherapy with autologous transplantation for patients with primary mediastinal nonseminomatous germ cell tumours: a prospective trial
    • Bokemeyer C, Schleucher N, Metzner B et al. First-line sequential high-dose VIP chemotherapy with autologous transplantation for patients with primary mediastinal nonseminomatous germ cell tumours: a prospective trial. Br J Cancer 2003; 89: 29-35.
    • (2003) Br J Cancer , vol.89 , pp. 29-35
    • Bokemeyer, C.1    Schleucher, N.2    Metzner, B.3
  • 52
    • 19944370162 scopus 로고    scopus 로고
    • First-line high-dose chemotherapy for patients with poor prognosis extragonadal germ cell tumors: the experience of the European Bone Marrow Transplantation (EBMT) Solid Tumors Working Party
    • Rosti G, De Giorgi U, Wandt H et al. First-line high-dose chemotherapy for patients with poor prognosis extragonadal germ cell tumors: the experience of the European Bone Marrow Transplantation (EBMT) Solid Tumors Working Party. Bone Marrow Transplant 2004; 34: 1033-1037.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 1033-1037
    • Rosti, G.1    De Giorgi, U.2    Wandt, H.3
  • 53
    • 39049178444 scopus 로고    scopus 로고
    • Is high-dose chemotherapy after primary chemotherapy a therapeutic option for patients with primary mediastinal nonseminomatous germ cell tumor
    • Banna GL, De Giorgi U, Ferrari B et al. Is high-dose chemotherapy after primary chemotherapy a therapeutic option for patients with primary mediastinal nonseminomatous germ cell tumor? Biol Blood Marrow Transplant 2006; 12: 1085-1091.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 1085-1091
    • Banna, G.L.1    De Giorgi, U.2    Ferrari, B.3
  • 54
    • 0035868955 scopus 로고    scopus 로고
    • Second line chemotherapy in patients with relapsed extragonadal nonseminomatous germ cell tumors: results of an international multicenter analysis
    • Hartmann JT, Einhorn L, Nichols CR et al. Second line chemotherapy in patients with relapsed extragonadal nonseminomatous germ cell tumors: results of an international multicenter analysis. J Clin Oncol 2001; 19: 1641-1648.
    • (2001) J Clin Oncol , vol.19 , pp. 1641-1648
    • Hartmann, J.T.1    Einhorn, L.2    Nichols, C.R.3
  • 55
    • 19944427229 scopus 로고    scopus 로고
    • Second-line high-dose chemotherapy in patients with mediastinal and retroperitoneal primary non-seminomatous germ cell tumors: the EBMT experience
    • De Giorgi U, Demirer T, Wandt H et al. Second-line high-dose chemotherapy in patients with mediastinal and retroperitoneal primary non-seminomatous germ cell tumors: the EBMT experience. Ann Oncol 2005; 16: 146-151.
    • (2005) Ann Oncol , vol.16 , pp. 146-151
    • De Giorgi, U.1    Demirer, T.2    Wandt, H.3
  • 56
    • 77953125223 scopus 로고    scopus 로고
    • FDA review summary: Mozobil in combination with granulocyte colony-stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation
    • Brave M, Farrell A, Ching Lin S et al. FDA review summary: Mozobil in combination with granulocyte colony-stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation. Oncology 2010; 78: 282-288.
    • (2010) Oncology , vol.78 , pp. 282-288
    • Brave, M.1    Farrell, A.2    Ching Lin, S.3


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