Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 13, 2012, Pages 4816-4821

  Murakami, Kenji ^a   Gibbons, Brian J ^a   Davis, Ralph E ^a   Nagai, Shigeki ^a   Liu, Xin ^a   Robinson, Philip J J ^a   Wu, Tinghe ^a   Kaplan, Craig D ^b   Kornberg, Roger D ^a  

^a STANFORD UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

DNA repair; General transcription factor; RNA polymerase II; TFIIK; Transcription pre initiation complex; Yeast

Indexed keywords

HELICASE; SSL2 HELICASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IIH; TRANSCRIPTION FACTOR TFB6; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SUBUNIT; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION;

CHROMATOGRAPHY, LIQUID; DNA HELICASES; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; MASS SPECTROMETRY; PHENOTYPE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN SUBUNITS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE; TRANSCRIPTION FACTOR TFIIH; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

EID: 84859460616     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1201448109     Document Type: Article

References (22)

1. Conaway RC, Conaway JW (1993) General initiation factors for RNA polymerase II. Annu Rev Biochem 62:161-190. (Pubitemid 23237869)
2. Svejstrup JQ, et al. (1995) Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome. Cell 80:21-28.
3. Chang WH, Kornberg RD (2000) Electron crystal structure of the transcription factor and DNA repair complex, core TFIIH. Cell 102:609-613.
4. Ranish JA, et al. (2004) Identification of TFB5, a new component of general transcription and DNA repair factor IIH. Nat Genet 36:707-713. (Pubitemid 38886631)
5. Giglia-Mari G, et al. (2004) A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A. Nat Genet 36:714-719. (Pubitemid 38886632)
6. Feaver WJ, Svejstrup JQ, Henry NL, Kornberg RD (1994) Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK. Cell 79:1103-1109.
7. Svejstrup JQ, Feaver WJ, Kornberg RD (1996) Subunits of yeast RNA polymerase II transcription factor TFIIH encoded by the CCL1 gene. J Biol Chem 271:643-645. (Pubitemid 26034909)
8. Takagi Y, et al. (2003) Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH. J Biol Chem 278:43897-43900. (Pubitemid 37377128)
9. Roy R, et al. (1994) The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell 79:1093-1101.
10. Gulyas KD, Donahue TF (1992) SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3. Cell 69:1031-1042.
11. Estruch F, Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14:1664-1676. (Pubitemid 36547430)
12. Mizuki F, et al. (2007) Participation of XPB/Ptr8p, a component of TFIIH, in nucleocytoplasmic transport of mRNA in fission yeast. Genes Cells 12:35-47. (Pubitemid 44971095)
13. Gibbons BJ, et al. (2012) Subunit architecture of general transcription factor TFIIH. Proc Natl Acad Sci USA 109:1949-1954.
14. Feaver WJ, et al. (1993) Dual roles of a multiprotein complex from S.cerevisiae in transcription and DNA repair. Cell 75:1379-1387. (Pubitemid 24021912)
15. Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440:631-636.
16. Brooks MA, et al. (2010) Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations. Structure 18:1075-1082.
17. Svejstrup JQ, Feaver WJ, LaPointe J, Kornberg RD (1994) RNA polymerase transcription factor IIH holoenzyme from yeast. J Biol Chem 269:28044-28048. (Pubitemid 24354535)
18. Lee BS, et al. (1998) Posttranslational inhibition of Ty1 retrotransposition by nucleotide excision repair/transcription factor TFIIH subunits Ssl2p and Rad3p. Genetics 148:1743-1761.
19. Borggrefe T, Davis R, Bareket-Samish A, Kornberg RD (2001) Quantitation of the RNA polymerase II transcription machinery in yeast. J Biol Chem 276:47150-47153.
20. Ranish JA, Lane WS, Hahn S (1992) Isolation of two genes that encode subunits of the yeast transcription factor IIA. Science 255:1127-1129.
21. Liu X, Bushnell DA, Wang D, Calero G, Kornberg RD (2009) Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science 327:206-209.
22. Sayre MH, Tschochner H, Kornberg RD (1992) Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae. J Biol Chem 267:23376-23382.