-
1
-
-
77949437015
-
Colorectal cancer
-
Cunningham D., Atkin W., Lenz H.J., Lynch H.T., Minsky B., Nordlinger B., et al. Colorectal cancer. Lancet 2010, 375:1030-1047.
-
(2010)
Lancet
, vol.375
, pp. 1030-1047
-
-
Cunningham, D.1
Atkin, W.2
Lenz, H.J.3
Lynch, H.T.4
Minsky, B.5
Nordlinger, B.6
-
2
-
-
78650082373
-
Consensus recommendations for the use of anti-EGFR therapies in metastatic colorectal cancer
-
Cripps C., Gill S., Ahmed S., Colwell B., Dowden S., Kennecke H., et al. Consensus recommendations for the use of anti-EGFR therapies in metastatic colorectal cancer. Curr Oncol 2010, 17:39-45.
-
(2010)
Curr Oncol
, vol.17
, pp. 39-45
-
-
Cripps, C.1
Gill, S.2
Ahmed, S.3
Colwell, B.4
Dowden, S.5
Kennecke, H.6
-
3
-
-
77955230057
-
Targeted therapy in advanced colorectal cancer: More data, more questions
-
Ochenduszko S.L., Krzemieniecki K. Targeted therapy in advanced colorectal cancer: More data, more questions. Anticancer Drugs 2010, 21:737-748.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 737-748
-
-
Ochenduszko, S.L.1
Krzemieniecki, K.2
-
4
-
-
53049087109
-
Genomic and epigenetic instability in colorectal cancer pathogenesis
-
Grady W.M., Carethers J.M. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 2008, 135:1079-1099.
-
(2008)
Gastroenterology
, vol.135
, pp. 1079-1099
-
-
Grady, W.M.1
Carethers, J.M.2
-
5
-
-
78651241644
-
Colorectal cancer molecular biology moves into clinical practice
-
Pritchard C.C., Grady W.M. Colorectal cancer molecular biology moves into clinical practice. Gut 2011, 60:116-129.
-
(2011)
Gut
, vol.60
, pp. 116-129
-
-
Pritchard, C.C.1
Grady, W.M.2
-
6
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
7
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
Malumbres M., Barbacid M. RAS oncogenes: The first 30 years. Nat Rev Cancer 2003, 3:459-465.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
8
-
-
84859439557
-
-
Cetuximab plus FOLFIRI in the treatment of metastatic colorectal cancer (mCRC): The influence of KRAS AND BRAF biomarkers on outcome: Updated data from the CRYSTAL trial. American Society of Clinical Oncology (ASCO) Gastrointestinal Cancer Symposium 2010. Proceedings of ASCO GI 2010. 22-1-2010. Abstract 281.
-
Van Cutsem E, Lang I, Folprecht G, Nowacki M, Cascinu S, Shchepotin I, et al. Cetuximab plus FOLFIRI in the treatment of metastatic colorectal cancer (mCRC): The influence of KRAS AND BRAF biomarkers on outcome: Updated data from the CRYSTAL trial. American Society of Clinical Oncology (ASCO) Gastrointestinal Cancer Symposium 2010. Proceedings of ASCO GI 2010. 2010. 22-1-2010. Abstract 281.
-
(2010)
-
-
Van Cutsem, E.1
Lang, I.2
Folprecht, G.3
Nowacki, M.4
Cascinu, S.5
Shchepotin, I.6
-
9
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D., Humblet Y., Siena S., Khayat D., Bleiberg H., Santoro A., et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004, 351:337-345.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
-
10
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
Saltz L.B., Meropol N.J., Loehrer P.J., Needle M.N., Kopit J., Mayer R.J. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004, 22:1201-1208.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer, P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
11
-
-
35648941728
-
Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: The BOND-2 study
-
Saltz L.B., Lenz H.J., Kindler H.L., Hochster H.S., Wadler S., Hoff P.M., et al. Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: The BOND-2 study. J Clin Oncol 2007, 25:4557-4561.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4557-4561
-
-
Saltz, L.B.1
Lenz, H.J.2
Kindler, H.L.3
Hochster, H.S.4
Wadler, S.5
Hoff, P.M.6
-
12
-
-
54949085398
-
KRAS mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis C.S., Khambata-Ford S., Jonker D.J., O'Callaghan C.J., Tu D., Tebbutt N.C., et al. KRAS mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008, 359:1757-1765.
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
-
13
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado R.G., Wolf M., Peeters M., Van Cutsem E., Siena S., Freeman D.J., et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008, 26:1626-1634.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
Van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
-
14
-
-
78149239651
-
Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer
-
Peeters M., Price T.J., Cervantes A., Sobrero A.F., Ducreux M., Hotko Y., et al. Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J Clin Oncol 2010, 28:4706-4713.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4706-4713
-
-
Peeters, M.1
Price, T.J.2
Cervantes, A.3
Sobrero, A.F.4
Ducreux, M.5
Hotko, Y.6
-
15
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study
-
Douillard J.Y., Siena S., Cassidy J., Tabernero J., Burkes R., Barugel M., et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010, 28:4697-4705.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
-
16
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C., Bondarenko I., Makhson A., Hartmann J.T., Aparicio J., de B.F., et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009, 27:663-671.
-
(2009)
J Clin Oncol
, vol.27
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
Hartmann, J.T.4
Aparicio, J.5
de, B.F.6
-
17
-
-
84859439558
-
-
Biomarkers predictive for outcome in patients with metastatic colorectal cancer (mCRC) treated with first-line FOLFOX4 plus or minus cetuximab: updated data from the OPUS study. American Society of Clinical Oncology (ASCO) Gastrointestinal Cancer Symposium 2010. Proceedings of ASCO GI 2010. 22-1-2010. Abstract 428
-
Bokemeyer C, Bondarenko I, Hartmann JT, De Braud FG, Schuch G, Zubel A, et al. Biomarkers predictive for outcome in patients with metastatic colorectal cancer (mCRC) treated with first-line FOLFOX4 plus or minus cetuximab: updated data from the OPUS study. American Society of Clinical Oncology (ASCO) Gastrointestinal Cancer Symposium 2010. Proceedings of ASCO GI 2010. 2010. 22-1-2010. Abstract 428.
-
(2010)
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartmann, J.T.3
De Braud, F.G.4
Schuch, G.5
Zubel, A.6
-
18
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E., Kohne C.H., Hitre E., Zaluski J., Chang Chien C.R., Makhson A., et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009, 360:1408-1417.
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Kohne, C.H.2
Hitre, E.3
Zaluski, J.4
Chang Chien, C.R.5
Makhson, A.6
-
19
-
-
84859442452
-
-
Cetuximab with chemotherapy (CT) as first-line treatment for metastatic colorectal cancer (mCRC): a meta-analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status. American Society of Clinical Oncology (ASCO) Gastrointestinal Cancer Symposium 2010. Proceedings of ASCO GI 2010. 22-1-2010. Abstract 406.
-
Kohne C, Rougier P, Stroh C, Schlichting M, Bokemeyer C, Van Cutsem E. Cetuximab with chemotherapy (CT) as first-line treatment for metastatic colorectal cancer (mCRC): a meta-analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status. American Society of Clinical Oncology (ASCO) Gastrointestinal Cancer Symposium 2010. Proceedings of ASCO GI 2010. 2010. 22-1-2010. Abstract 406.
-
(2010)
-
-
Kohne, C.1
Rougier, P.2
Stroh, C.3
Schlichting, M.4
Bokemeyer, C.5
Van Cutsem, E.6
-
20
-
-
73249130298
-
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
-
Folprecht G., Gruenberger T., Bechstein W.O., Raab H.R., Lordick F., Hartmann J.T., et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 2010, 11:38-47.
-
(2010)
Lancet Oncol
, vol.11
, pp. 38-47
-
-
Folprecht, G.1
Gruenberger, T.2
Bechstein, W.O.3
Raab, H.R.4
Lordick, F.5
Hartmann, J.T.6
-
21
-
-
78049341541
-
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
-
De Roock W., Jonker D.J., Di Nicolantonio F., Sartore-Bianchi A., Tu D., Siena S., et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA 2010, 304:1812-1820.
-
(2010)
JAMA
, vol.304
, pp. 1812-1820
-
-
De Roock, W.1
Jonker, D.J.2
Di Nicolantonio, F.3
Sartore-Bianchi, A.4
Tu, D.5
Siena, S.6
|