Study the pharmacokinetics of AV-45 in rat plasma and metabolism in liver microsomes by ultra-performance liquid chromatography with mass spectrometry

Biomedical Chromatography

Volumn 26, Issue 5, 2012, Pages 666-671

  Yin, Wei ^a   Zhou, Xue ^a   Qiao, Jinping ^a   Zhu, Lin ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

AV 45; LC MS MS; Metabolites; Microsomes; Pharmacokinetics; Rat plasma

Indexed keywords

BIOMOLECULES; BODY FLUIDS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES; PHYSIOLOGY; POSITIVE IONS; PRECIPITATION (CHEMICAL); RATS;

AV-45; INTERNAL STANDARDS; LC-MS-MS; LC.MS/MS; LIVER MICROSOMES; MATRICES EFFECT; MICROSOME; RAT PLASMA; TANDEM MASS SPECTROMETRIC; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

PHARMACOKINETICS;

AV 45; BENZOPHENONE; FLORBETAPIR F 18; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STRUCTURE; LIVER MICROSOME; MALE; MASS SPECTROMETRY; METABOLISM; NONHUMAN; PHARMACODYNAMICS; PLASMA; RAT; STANDARD; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

RATTUS;

EID: 84859443015     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1714     Document Type: Article

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