A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid, to phosphate buffered saline for treatment of osteoarthritis of the knee

Osteoarthritis and Cartilage

Volumn 20, Issue 5, 2012, Pages 350-356

  Strand, V ^a   Baraf, H S B ^b   Lavin, P T ^c   Lim, S ^d   Hosokawa, H ^d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Center for Rheumatology and Bone Research   (United States)

^c Boston Biostatistics Research Foundation   (United States)

^d SEIKAGAKU CORPORATION   (Japan)

Author keywords

Cross linked HA; Gel 200; Hyaluronic acid; Knee; Osteoarthritis

Indexed keywords

ANTIRHEUMATIC AGENT; CHONDROITIN SULFATE; GEL 200; GEL ONE; GLUCOSAMINE; HYALURONIC ACID; HYALURONIC ACID DERIVATIVE; MINOCYCLINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; PHOSPHATE BUFFERED SALINE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTHRALGIA; ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERANCE; FEMALE; HUMAN; JOINT ASPIRATION; JOINT EFFUSION; JOINT SWELLING; KNEE; KNEE OSTEOARTHRITIS; KNEE PAIN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OUTCOME ASSESSMENT; PATIENT AND PHYSICIAN GLOBAL ASSESSMENT; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; STATISTICAL SIGNIFICANCE; VISUAL ANALOG SCALE; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX;

AGED; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT; SEVERITY OF ILLNESS INDEX; SODIUM CHLORIDE; TREATMENT OUTCOME; VISCOSUPPLEMENTATION; VISCOSUPPLEMENTS;

EID: 84859434114     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.01.013     Document Type: Article

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