Strontium ranelate treatment increases osteoprotegerin serum levels in postmenopausal osteoporotic women

Bone

Volumn 50, Issue 5, 2012, Pages 1201-1202

  Reginster, J Y ^a   Bruyere, O ^b   Collette, J ^b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; AMINO TERMINAL TELOPEPTIDE; CARBOXY TERMINAL TELOPEPTIDE; OSTEOPROTEGERIN; STRONTIUM RANELATE;

BONE TURNOVER; DRUG EFFICACY; FEMALE; HUMAN; LETTER; OSSIFICATION; OSTEOBLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; PROTEIN BLOOD LEVEL; PROTEIN CROSS LINKING; VERTEBRA FRACTURE;

ANIMALS; FEMALE; OSTEOBLASTS; OSTEOCLASTS; OSTEOPROTEGERIN; STRONTIUM;

EID: 84859423461     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.12.024     Document Type: Letter

References (6)

1. Peng S., Liu X.S., Huang S., Li Z., Pan H., Zhen W., Luk K.D., Guo X.E., Lu W.W. The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin. Bone 2011, 49:1290-1298.
2. Peng S., Liu X.S., Zhou G., Li Z., Luk K.D., Guo X.E., Lu W.W. Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption. J Bone Miner Res 2011, 26:1272-1282.
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4. Reginster J.Y., Seeman E., De Vernejoul M.C., Adami S., Compston J., Phenekos C., Devogelaer J.P., Curiel M.D., Sawicki A., Goemaere S., Sorensen O.H., Felsenberg D., Meunier P.J. Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. J Clin Endocrinol Metab 2005, 90:2816-2822.
5. Marie P.J., Felsenberg D., Brandi M.L. How strontium ranelate, via opposite effects on bone resorption and formation, prevents osteoporosis. Osteoporos Int 2011, 22:1659-1667.
6. Bruyere O., Collette J., Reginster J.Y. The effects of strontium ranelate on biochemical markers of bone turnover and their relationship with bone mineral density. Osteoporos Int 2010, 21:1039-1040.