Human macrophage ATP7A is localized in the trans-Golgi apparatus, controls intracellular copper levels, and mediates macrophage responses to dermal wounds

Inflammation

Volumn 35, Issue 1, 2012, Pages 167-175

  Kim, Ha Won ^a   Chan, Qilin ^a,b   Afton, Scott E ^a,b   Caruso, Joseph A ^b   Lai, Barry ^c   Weintraub, Neal L ^a   Qin, Zhenyu ^a,d  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

^d Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

ATP7A; Copper; Macrophage

Indexed keywords

CD68 ANTIGEN; COPPER; MENKES PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATP7A GENE; CELL ISOLATION; CELL LEVEL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FLUORESCENCE MICROSCOPY; GENE; GENE EXPRESSION REGULATION; GENE LOCATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SKIN INJURY;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CATION TRANSPORT PROTEINS; CELL LINE; COPPER; FEMALE; GOLGI APPARATUS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MACROPHAGES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, NUDE; RNA, MESSENGER; SKIN; TRANS-GOLGI NETWORK;

MURINAE; MUS; MUS MUSCULUS;

EID: 84859422890     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9302-z     Document Type: Article

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