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Volumn 78, Issue 4, 2012, Pages 473-482

Myths and facts in neuromuscular pharmacology - New developments in reversing neuromuscular blockade

Author keywords

Acetylcholinesterase; Neuromuscular blockade; Pharmacology

Indexed keywords

ACETYLCHOLINESTERASE; ATRACURIUM; ATROPINE; CHOLINESTERASE INHIBITOR; CISATRACURIUM; GLYCOPYRRONIUM BROMIDE; MUSCLE RELAXANT AGENT; PANCURONIUM; ROCURONIUM; SUGAMMADEX; VECURONIUM;

EID: 84859414160     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (17)

References (57)
  • 2
    • 0034821030 scopus 로고    scopus 로고
    • Sevoflurane with remifentanil allows rapid tracheal intubation without neuromuscular blocking agents
    • Joo HS, Perks WJ, Belo SE. Sevoflurane with remifentanil allows rapid tracheal intubation without neuromuscular blocking agents. Can J Anaesth 2001;48:646-50.
    • (2001) Can J Anaesth , vol.48 , pp. 646-650
    • Joo, H.S.1    Perks, W.J.2    Belo, S.E.3
  • 3
    • 33645106917 scopus 로고    scopus 로고
    • Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants
    • Gupta A, Kaur R, Malhotra R, Kale S. Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants. Paediatr Anaesth 2006;16:399-405.
    • (2006) Paediatr Anaesth , vol.16 , pp. 399-405
    • Gupta, A.1    Kaur, R.2    Malhotra, R.3    Kale, S.4
  • 6
    • 34547918318 scopus 로고    scopus 로고
    • Comparison of two induction regimens using or not using muscle relaxant: Impact on postoperative upper airway discomfort
    • Combes X, Andriamifidy L, Dufresne E, Suen P, Sauvat S, Scherrer E et al. Comparison of two induction regimens using or not using muscle relaxant: impact on postoperative upper airway discomfort. Br J Anaesth 2007;99:276-81.
    • (2007) Br J Anaesth , vol.99 , pp. 276-281
    • Combes, X.1    Andriamifidy, L.2    Dufresne, E.3    Suen, P.4    Sauvat, S.5    Scherrer, E.6
  • 7
    • 0034086433 scopus 로고    scopus 로고
    • Remifentanil and propofol without muscle relaxants or with different doses of rocuronium for tracheal intubation in outpatient anaesthesia
    • Schlaich N, Mertzlufft F, Soltesz S, Fuchs-Buder T. Remifentanil and propofol without muscle relaxants or with different doses of rocuronium for tracheal intubation in outpatient anaesthesia. Acta Anaesthesiol Scand 2000;44:720-6.
    • (2000) Acta Anaesthesiol Scand , vol.44 , pp. 720-726
    • Schlaich, N.1    Mertzlufft, F.2    Soltesz, S.3    Fuchs-Buder, T.4
  • 8
    • 0037302417 scopus 로고    scopus 로고
    • Muscle relaxation and increasing doses of propofol improve intubating conditions
    • Lieutaud T, Billard V, Khalaf H, Debaene B. Muscle relaxation and increasing doses of propofol improve intubating conditions. Can J Anaesth 2003;50:121-6.
    • (2003) Can J Anaesth , vol.50 , pp. 121-126
    • Lieutaud, T.1    Billard, V.2    Khalaf, H.3    Debaene, B.4
  • 11
    • 77950863126 scopus 로고    scopus 로고
    • Residual paralysis after emergence from anesthesia
    • Plaud B, Debaene B, Donati F, Marty J. Residual paralysis after emergence from anesthesia. Anesthesiology 2010;112:1013-22.
    • (2010) Anesthesiology , vol.112 , pp. 1013-1022
    • Plaud, B.1    Debaene, B.2    Donati, F.3    Marty, J.4
  • 12
    • 78349255889 scopus 로고    scopus 로고
    • Residual paralysis following a single dose of atracurium: Results from a quality assurance trial
    • Schreiber JU, Mucha E, Fuchs-Buder T. Residual paralysis following a single dose of atracurium: results from a quality assurance trial. Eur J Anaesthesiol 2010;27:993-4.
    • (2010) Eur J Anaesthesiol , vol.27 , pp. 993-994
    • Schreiber, J.U.1    Mucha, E.2    Fuchs-Buder, T.3
  • 13
    • 33644942363 scopus 로고    scopus 로고
    • Residual neuromuscular blockade: Incidence, assessment, and relevance in the postoperative period
    • Murphy GS. Residual neuromuscular blockade: incidence, assessment, and relevance in the postoperative period. Minerva Anestesiol 2006;72:97-109.
    • (2006) MinErva Anestesiol , vol.72 , pp. 97-109
    • Murphy, G.S.1
  • 14
    • 33845317613 scopus 로고    scopus 로고
    • Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium
    • Maybauer DM, Geldner G, Blobner M, Puhringer F, Hof M.R, Rex C et al. Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium. Anaesthesia 2007;62: 12-7.
    • (2007) Anaesthesia , vol.62 , pp. 12-17
    • Maybauer, D.M.1    Geldner, G.2    Blobner, M.3    Puhringer, F.4    Hof, M.R.5    Rex, C.6
  • 15
    • 0030657843 scopus 로고    scopus 로고
    • Residual neuromuscular block is a risk factor for postoperative pulmonary complications. A prospective, randomised, and blinded study of postoperative pulmonary complications after atracurium, vecuronium and pancuronium
    • Berg H, Roed J, Viby-Mogensen J, Mortensen CR, Engbaek J, Skovgaard LT et al. Residual neuromuscular block is a risk factor for postoperative pulmonary complications. A prospective, randomised, and blinded study of postoperative pulmonary complications after atracurium, vecuronium and pancuronium. Acta Anaesthesiol Scand 1997;41:1095-103.
    • (1997) Acta Anaesthesiol Scand , vol.41 , pp. 1095-1103
    • Berg, H.1    Roed, J.2    Viby-Mogensen, J.3    Mortensen, C.R.4    Engbaek, J.5    Skovgaard, L.T.6
  • 16
    • 33746233430 scopus 로고    scopus 로고
    • Muscle relaxants in Germany 2005: A comparison of application customs in hospitals and private practices
    • Fink H, Geldner G, Fuchs-Buder T, Hofmockel R, Ulm K, Wallek B et al. [Muscle relaxants in Germany 2005: A comparison of application customs in hospitals and private practices.]. Anaesthesist 2006;55:668-78.
    • (2006) Anaesthesist , vol.55 , pp. 668-678
    • Fink, H.1    Geldner, G.2    Fuchs-Buder, T.3    Hofmockel, R.4    Ulm, K.5    Wallek, B.6
  • 17
    • 0030730673 scopus 로고    scopus 로고
    • Functional assessment of the pharynx at rest and during swallowing in partially paralyzed humans. Simultaneous videomanometry and mechanomyography of awake human volunteers
    • Eriksson LI, Sundman E, Olsson R, Nilsson L, Witt H, Ekberg O et al. Functional assessment of the pharynx at rest and during swallowing in partially paralyzed humans. Simultaneous videomanometry and mechanomyography of awake human volunteers. Anesthesiology 1997;87:1035-43.
    • (1997) Anesthesiology , vol.87 , pp. 1035-1043
    • Eriksson, L.I.1    Sundman, E.2    Olsson, R.3    Nilsson, L.4    Witt, H.5    Ekberg, O.6
  • 18
    • 0034071051 scopus 로고    scopus 로고
    • The incidence and mechanisms of pharyngeal and upper esophageal dysfunction in partially paralyzed humans. Pharyngeal videoradiography and simultaneous manometry after atracurium
    • Sundman E, Witt H, Olsson R, Ekberg O, Kuylenstierna R, Eriksson LI. The incidence and mechanisms of pharyngeal and upper esophageal dysfunction in partially paralyzed humans. Pharyngeal videoradiography and simultaneous manometry after atracurium. Anesthesiology 2000;92:977-84.
    • (2000) Anesthesiology , vol.92 , pp. 977-984
    • Sundman, E.1    Witt, H.2    Olsson, R.3    Ekberg, O.4    Kuylenstierna, R.5    Eriksson, L.I.6
  • 19
    • 0029984852 scopus 로고    scopus 로고
    • Reduced hypoxic chemosensitivity in partially paralysed man. A new property of muscle relaxants
    • Eriksson LI. Reduced hypoxic chemosensitivity in partially paralysed man. A new property of muscle relaxants? Acta Anaesthesiol Scand 1996;40:520-3.
    • (1996) Acta Anaesthesiol Scand , vol.40 , pp. 520-523
    • Eriksson, L.I.1
  • 21
    • 0018770642 scopus 로고
    • Residual curarization in the recovery room
    • Viby Mogensen J, Chraemer Jorgensen B, Ording H. Residual curarization in the recovery room. Anesthesiology 1979;50:539-41.
    • (1979) Anesthesiology , vol.50 , pp. 539-541
    • Viby, M.J.1    Chraemer, J.B.2    Ording, H.3
  • 24
    • 0031771695 scopus 로고    scopus 로고
    • Tactile evaluation of the response to double burst stimulation decreases, but does not eliminate, the problem of postoperative residual paralysis
    • Fruergaard K, Viby-Mogensen J, Berg H, el-Mahdy AM. Tactile evaluation of the response to double burst stimulation decreases, but does not eliminate, the problem of postoperative residual paralysis. Acta Anaesthesiol Scand 1998;42:1168-74.
    • (1998) Acta Anaesthesiol Scand , vol.42 , pp. 1168-1174
    • Fruergaard, K.1    Viby-Mogensen, J.2    Berg, H.3    El-Mahdy, A.M.4
  • 26
    • 0024600719 scopus 로고
    • Manual evaluation of residual curarization using double burst stimulation: A comparison with train-of- four
    • Drenck NE, Ueda N, Olsen NV, Engboek J, Jensen E, Skovgaard LT et al. Manual evaluation of residual curarization using double burst stimulation: a comparison with train-of- four. Anesthesiology 1989;70:578-81.
    • (1989) Anesthesiology , vol.70 , pp. 578-581
    • Drenck, N.E.1    Ueda, N.2    Olsen, N.V.3    Engboek, J.4    Jensen, E.5    Skovgaard, L.T.6
  • 27
    • 0037406756 scopus 로고    scopus 로고
    • Evidence-based practice and neuromuscular monitoring: It's time for routine quantitative assessment
    • Eriksson LI. Evidence-based practice and neuromuscular monitoring: it's time for routine quantitative assessment. Anesthesiology 2003;98:1037-9.
    • (2003) Anesthesiology , vol.98 , pp. 1037-1039
    • Eriksson, L.I.1
  • 28
    • 6844243070 scopus 로고
    • The antagonism of curare: The cardiac effects of atropine and neostigmine
    • Gottlieb JD, Sweet RB. The antagonism of curare: the cardiac effects of atropine and neostigmine. Can Anaesth Soc J 1963;10:114-21.
    • (1963) Can Anaesth Soc J , vol.10 , pp. 114-121
    • Gottlieb, J.D.1    Sweet, R.B.2
  • 29
    • 0019508574 scopus 로고
    • The effect on heart rate of neuromuscular blockade reversal by pyridostigmine
    • Long G, Marsh HM. The effect on heart rate of neuromuscular blockade reversal by pyridostigmine. Anaesth Intensive Care 1981;9:144-6.
    • (1981) Anaesth Intensive Care , vol.9 , pp. 144-146
    • Long, G.1    Marsh, H.M.2
  • 30
    • 0023138201 scopus 로고
    • Adverse cardiovascular effects of anticholinesterase medications
    • Arsura EL, Brunner NG, Namba T, Grob D. Adverse cardiovascular effects of anticholinesterase medications. Am J Med Sci 1987;293:18-23.
    • (1987) Am J Med Sci , vol.293 , pp. 18-23
    • Arsura, E.L.1    Brunner, N.G.2    Namba, T.3    Grob, D.4
  • 31
    • 0023910282 scopus 로고
    • Bronchospasm after neostigmine
    • Pratt CI. Bronchospasm after neostigmine. Anaesthesia 1988;43:248.
    • (1988) Anaesthesia , vol.43 , pp. 248
    • Pratt, C.I.1
  • 32
    • 67650713727 scopus 로고    scopus 로고
    • Reversal of neuromuscular block
    • Srivastava A, Hunter JM. Reversal of neuromuscular block. Br J Anaesth 2009;103:115-29.
    • (2009) Br J Anaesth , vol.103 , pp. 115-129
    • Srivastava, A.1    Hunter, J.M.2
  • 33
    • 0033565321 scopus 로고    scopus 로고
    • Neostigmine for the treatment of acute colonic pseudo-obstruction
    • Ponec RJ, Saunders MD, Kimmey MB. Neostigmine for the treatment of acute colonic pseudo-obstruction. N Engl J Med 1999;341:137-41.
    • (1999) N Engl J Med , vol.341 , pp. 137-141
    • Ponec, R.J.1    Saunders, M.D.2    Kimmey, M.B.3
  • 35
    • 0023219769 scopus 로고
    • Incomplete reversal of pancuronium neuromuscular blockade by neostigmine, pyridostigmine, and edrophonium
    • Bartkowski RR. Incomplete reversal of pancuronium neuromuscular blockade by neostigmine, pyridostigmine, and edrophonium. Anesthesia and Analgesia 1987;66:594-8.
    • (1987) Anesthesia and Analgesia , vol.66 , pp. 594-598
    • Bartkowski, R.R.1
  • 36
    • 13844256446 scopus 로고    scopus 로고
    • Antagonism of profound cisatracurium and rocuronium block: The role of objective assessment of neuromuscular function
    • Kopman A, Kopman D, Ng J, Zank L. Antagonism of profound cisatracurium and rocuronium block: the role of objective assessment of neuromuscular function. J Clin Anesth 2005;17:30-5.
    • (2005) J Clin Anesth , vol.17 , pp. 30-35
    • Kopman, A.1    Kopman, D.2    Ng, J.3    Zank, L.4
  • 37
    • 0032984506 scopus 로고    scopus 로고
    • Pharmacodynamics and the plasma concentration of mivacurium during spontaneous recovery and neostigmine-facilitated recovery
    • Lien CA, Belmont MR, Wray Roth DL, Okamoto M, Abalos A, Savarese JJ. Pharmacodynamics and the plasma concentration of mivacurium during spontaneous recovery and neostigmine-facilitated recovery. Anesthesiology 1999;91:119-26.
    • (1999) Anesthesiology , vol.91 , pp. 119-126
    • Lien, C.A.1    Belmont, M.R.2    Wray, R.D.L.3    Okamoto, M.4    Abalos, A.5    Savarese, J.J.6
  • 39
    • 79953680159 scopus 로고    scopus 로고
    • Sugammadex is cleared rapidly and primarily unchanged via renal excretion
    • Peeters P, Passier P, Smeets J, Zwiers A, de Zwart M, van de Wetering-Krebbers S et al. Sugammadex is cleared rapidly and primarily unchanged via renal excretion. Biopharm Drug Dispos 2011;32:159-67.
    • (2011) Biopharm Drug Dispos , vol.32 , pp. 159-167
    • Peeters, P.1    Passier, P.2    Smeets, J.3    Zwiers, A.4    de Zwart, M.5
  • 40
    • 48849112776 scopus 로고    scopus 로고
    • Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: An international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial
    • Puhringer FK, Rex C, Sielenkamper AW, Claudius C, Larsen PB, Prins ME et al. Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: an international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial. Anesthesiology 2008;109:188-97.
    • (2008) Anesthesiology , vol.109 , pp. 188-197
    • Puhringer, F.K.1    Rex, C.2    Sielenkamper, A.W.3    Claudius, C.4    Larsen, P.B.5    Prins, M.E.6
  • 41
    • 56149116295 scopus 로고    scopus 로고
    • Reversal of profound rocuronium-induced blockade with sugammadex: A randomized comparison with neostigmine
    • Jones RK, Caldwell JE, Brull SJ, Soto RG. Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine. Anesthesiology 2008;109:816-24.
    • (2008) Anesthesiology , vol.109 , pp. 816-824
    • Jones, R.K.1    Caldwell, J.E.2    Brull, S.J.3    Soto, R.G.4
  • 42
    • 33846586403 scopus 로고    scopus 로고
    • Effective reversal of moderate rocuronium- or vecuronium-induced neuromuscular block with sugammadex, a selective relaxant binding agent
    • Suy K, Morias K, Cammu G, Hans P, van Duijnhoven WG, Heeringa M, Demeyer I. Effective reversal of moderate rocuronium- or vecuronium-induced neuromuscular block with sugammadex, a selective relaxant binding agent. Anesthesiology 2007;106:283-88.
    • (2007) Anesthesiology , vol.106 , pp. 283-288
    • Suy, K.1    Morias, K.2    Cammu, G.3    Hans, P.4    van Duijnhoven, W.G.5    Heeringa, M.6    Demeyer, I.7
  • 43
    • 31144448393 scopus 로고    scopus 로고
    • Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block
    • Shields M, Giovannelli M, Mirakhur R, Moppett I, Adams J, Hermens Y. Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block. Br J Anaesth 2006;96:36-43.
    • (2006) Br J Anaesth , vol.96 , pp. 36-43
    • Shields, M.1    Giovannelli, M.2    Mirakhur, R.3    Moppett, I.4    Adams, J.5    Hermens, Y.6
  • 44
    • 78049345252 scopus 로고    scopus 로고
    • Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block
    • Schaller SJ, Fink H, Ulm K, Blobner M. Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block. Anesthesiology 2010;113:1054-60.
    • (2010) Anesthesiology , vol.113 , pp. 1054-1060
    • Schaller, S.J.1    Fink, H.2    Ulm, K.3    Blobner, M.4
  • 46
    • 84859418876 scopus 로고    scopus 로고
    • Clinical trials.gov, Study P06042, (COMPLETED) [Internet]. [cited 2012 February 21]. Available at
    • Clinical trials.gov. Sugammadex Hypersensitivity Study (Study P06042) (COMPLETED) [Internet]. [cited 2012 February 21]. Available at: http://clinicaltrials.gov/ct2/ show/NCT00988065
    • Sugammadex Hypersensitivity Study
  • 47
    • 77956892310 scopus 로고    scopus 로고
    • Repeat dosing of rocuronium 1.2 mg kg-1 after reversal of neuromuscular block by sugammadex 4.0 mg kg-1 in anaesthetized healthy volunteers: A modelling-based pilot study
    • Cammu G, de Kam PJ, De Graeve K, Van Den Heuvel M, Suy K, Morias K et al. Repeat dosing of rocuronium 1.2 mg kg-1 after reversal of neuromuscular block by sugammadex 4.0 mg kg-1 in anaesthetized healthy volunteers: a modelling-based pilot study. Br J Anaesth 2010;105:487-92.
    • (2010) Br J Anaesth , vol.105 , pp. 487-492
    • Cammu, G.1    de Kam, P.J.2    de Graeve, K.3    van Den, H.M.4    Suy, K.5    Morias, K.6
  • 48
    • 51849115179 scopus 로고    scopus 로고
    • Multicentre, parallel-group, comparative trial evaluating the efficacy and safety of sugammadex in patients with end-stage renal failure or normal renal function
    • Staals LM, Snoeck MM, Driessen JJ, Flockton EA, Heeringa M, Hunter JM. Multicentre, parallel-group, comparative trial evaluating the efficacy and safety of sugammadex in patients with end-stage renal failure or normal renal function. Br J Anaesth 2008;101:492-7.
    • (2008) Br J Anaesth , vol.101 , pp. 492-497
    • Staals, L.M.1    Snoeck, M.M.2    Driessen, J.J.3    Flockton, E.A.4    Heeringa, M.5    Hunter, J.M.6
  • 50
    • 79957519704 scopus 로고    scopus 로고
    • Reversibility of rocuronium-induced profound neuromuscular block with sugammadex in younger and older patients
    • Epub ahead of print
    • Suzuki T, Kitajima O, Ueda K, Kondo Y, Kato J, Ogawa S. Reversibility of rocuronium-induced profound neuromuscular block with sugammadex in younger and older patients. Br J Anaesth 2011 [Epub ahead of print].
    • (2011) Br J Anaesth
    • Suzuki, T.1    Kitajima, O.2    Ueda, K.3    Kondo, Y.4    Kato, J.5    Ogawa, S.6
  • 51
    • 67649565435 scopus 로고    scopus 로고
    • Rapid sequence induction in obstetrics revisited
    • Sharp LM, Levy DM. Rapid sequence induction in obstetrics revisited. Curr Opin Anaesthesiol 2009;22:357-61.
    • (2009) Curr Opin Anaesthesiol , vol.22 , pp. 357-361
    • Sharp, L.M.1    Levy, D.M.2
  • 52
    • 77958191003 scopus 로고    scopus 로고
    • Sugammadex reversal of rocuronium-induced neuromuscular block in Caesarean section patients: A series of seven cases
    • Puhringer FK, Kristen P, Rex C. Sugammadex reversal of rocuronium-induced neuromuscular block in Caesarean section patients: a series of seven cases. Br J Anaesth 2010;105:657-60.
    • (2010) Br J Anaesth , vol.105 , pp. 657-660
    • Puhringer, F.K.1    Kristen, P.2    Rex, C.3
  • 53
    • 79959850200 scopus 로고    scopus 로고
    • Rocuronium and sugammadex for rapid sequence induction of obstetric general anaesthesia
    • Epub ahead of print
    • Williamson RM, Mallaiah S, Barclay P. Rocuronium and sugammadex for rapid sequence induction of obstetric general anaesthesia. Acta Anaesthesiol Scand 2011 [Epub ahead of print].
    • (2011) Acta Anaesthesiol Scand
    • Williamson, R.M.1    Mallaiah, S.2    Barclay, P.3
  • 54
    • 84859382470 scopus 로고    scopus 로고
    • US Food and Drug Administration, Sugammadex, NDA 22-225, March 11, 2008. Available at
    • US Food and Drug Administration. Sugammadex, NDA 22-225, Anesthetic and Life Support Drugs Advisory Committee March 11, 2008. Available at: http://wwwfdagov/ohrms/dockets/ac/08/slides/2008-4346s1-01-Schering-Plough-corebackuppdf2008.
    • (2008) Anesthetic and Life Support Drugs Advisory Committee
  • 55
    • 78650300680 scopus 로고    scopus 로고
    • Assessment of the potential for displacement interactions with sugammadex: A pharmacokinetic-pharmacodynamic modelling approach
    • Zwiers A, van den Heuvel M, Smeets J, Rutherford S. Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach. Clin Drug Investig 2011;31:101-11.
    • (2011) Clin Drug Investig , vol.31 , pp. 101-111
    • Zwiers, A.1    van den Heuvel, M.2    Smeets, J.3    Rutherford, S.4
  • 56
    • 77958158907 scopus 로고    scopus 로고
    • Sugammadex for reversal of neuromuscular block after rapid sequence intubation: A systematic review and economic assessment
    • Chambers D, Paulden M, Paton F, Heirs M, Duffy S, Hunter JM et al. Sugammadex for reversal of neuromuscular block after rapid sequence intubation: a systematic review and economic assessment. Br J Anaesth 2010;105: 568-75.
    • (2010) Br J Anaesth , vol.105 , pp. 568-575
    • Chambers, D.1    Paulden, M.2    Paton, F.3    Heirs, M.4    Duffy, S.5    Hunter, J.M.6
  • 57
    • 77958197305 scopus 로고    scopus 로고
    • Sugammadex compared with neostigmine/glycopyrrolate for routine reversal of neuromuscular block: A systematic review and economic evaluation
    • Paton F, Paulden M, Chambers D, Heirs M, Duffy S, Hunter JM et al. Sugammadex compared with neostigmine/glycopyrrolate for routine reversal of neuromuscular block: a systematic review and economic evaluation. Br J Anaesth 2010;105:558-67.
    • (2010) Br J Anaesth , vol.105 , pp. 558-567
    • Paton, F.1    Paulden, M.2    Chambers, D.3    Heirs, M.4    Duffy, S.5    Hunter, J.M.6


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