Exome versus transcriptome sequencing in identifying coding region variants

Expert Review of Molecular Diagnostics

Volumn 12, Issue 3, 2012, Pages 241-251

  Ku, Chee Seng ^a   Wu, Mengchu ^a   Cooper, David N ^b   Naidoo, Nasheen ^c   Pawitan, Yudi ^d   Pang, Brendan ^e   Iacopetta, Barry ^f   Soong, Richie ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d KAROLINSKA INSTITUTE   (Sweden)

^e NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^f UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

exome; exome enrichment; next generation sequencing; single nucleotide variants; transcriptome

Indexed keywords

DNA FRAGMENT; TRANSCRIPTOME; UNTRANSLATED RNA;

CANCER GENETICS; EXOME; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC CODE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN GENOME; MEDICAL TECHNOLOGY; POLYMERASE CHAIN REACTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION;

BASE SEQUENCE; EXOME; GENETIC VARIATION; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 84859413165     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/erm.12.10     Document Type: Review

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