Biliary dysplasia in patients with primary sclerosing cholangitis: Additional value of DNA ploidity

Liver International

Volumn 32, Issue 5, 2012, Pages 783-789

  Halme, Leena ^a   Arola, Johanna ^b   Numminen, Kirsti ^a   Krogerus, Leena ^b   Mäkisalo, Heikki ^a   Färkkilä, Martti ^c  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Brush cytology; Cholangiocancer; DNA content; Flow cytometry; Hepatobiliary malignancy

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; TUMOR MARKER;

ANEUPLOIDY; ARTICLE; BILE DUCT CANCER; BILIARY TRACT EXAMINATION; BRUSH CYTOLOGY; CANCER DIAGNOSIS; CANCER SURGERY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOLOGY; DNA CONTENT; DNA DETERMINATION; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FLOW CYTOMETRY; GALLBLADDER CANCER; HEPATOBILIARY DISEASE; HEPATOBILIARY DYSPLASIA; HEPATOBILIARY SYSTEM CANCER; HUMAN; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; PREDICTIVE VALUE; PRIMARY SCLEROSING CHOLANGITIS; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

ADULT; BILIARY TRACT NEOPLASMS; BIOPSY; CA-19-9 ANTIGEN; CHOLANGIOCARCINOMA; CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE; CHOLANGITIS, SCLEROSING; DNA, NEOPLASM; FLOW CYTOMETRY; HUMANS; PLOIDIES; PROSPECTIVE STUDIES; TUMOR MARKERS, BIOLOGICAL;

EID: 84859411320     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02672.x     Document Type: Article

References (22)

1. Ponsioen CY, Vrouenraets SM, Prawirodirdjo W, et al. Natural history of primary sclerosing cholangitis and prognostic value of the cholangiography in a Dutch population. Gut 2002; 51: 562-6.
2. Bergquist A, Ekbom A, Olsson R, et al. Hepatic and extrahepatic malignancies in primary sclerosing cholangitis. J Hepatol 2002; 36: 321-7.
3. Wiesner RH, Grambsch PM, Dickson ER, et al. Primary sclerosing cholangitis-natural-history, prognostic factors and survival analysis. Hepatology 1989; 10: 430-6.
4. Ahrendt SA, Pitt HA, Nakeeb A, et al. Diagnosis and management of cholangiocancer in primary sclerosing cholangitis. J Gastrointest Surg 1999; 3: 357-68.
5. Boberg KM, Bergquist A, Mitchell S, et al. Cholangiocancer in primary sclerosing cholangitis: risk factors and clinical presentation. Scand J Gastroenterol 2002; 37: 1205-11.
6. Broome U, Olsson R, Loof L, et al. Natural history and prognostic factors in 305 Swedish patients with primary sclerosing cholangitis. Gut 1996; 38: 610-5.
7. Burak K, Angulo P, Pasha TM, et al. Incidence and risk factors for cholangiocarcinoma in primary sclerosing cholangitis. Am J Gastroenterol 2004; 99: 523-6.
8. Levy C, Lymp J, Angulo P, et al. The value of serum CA 19-9 in predicting cholangiocancer in patients with primary sclerosing cholangitis. Dig Dis Sci 2005; 50: 1734-40.
9. Lindberg B, Arnelo U, Bergqvist A, et al. Diagnosis of biliary strictures in conjunction with endocopic retrograde cholangiopancreaticography, with special reference to patients with primary sclerosing cholangitis. Endoscopy 2002; 34: 909-16.
10. Boberg K, Jebsen P, Clausen O, et al. Diagnostic benefit of biliary brush cytology in cholangiocancer in primary sclerosing cholangitis. J Hepatol 2006; 45: 568-74.
11. Charatcharoenwitthaya P, Enders FB, Halling KC, Lindor KD. Utility of serum tumor markers, imaging, and biliary cytology for detecting cholangiocancer in primary sclerosing cholangitis. Hepatology 2008; 48: 1106-17.
12. Baisch H, Gerdes J. Simultaneous staining of exponentially growing versus plateau phase cells with the proliferation - associated antibody Ki-67 and propidium iodine: analysis by flow cytometry. Cell Tissue Kinet 1987; 20: 387-91.
13. Bergqvist A, Tribukait B, Glaumann H, Broome U. Can DNA cytometry be used for evaluation of malignancy and premalignancy in bile duct strictures in primary sclerosing cholangitis? J Hepatol 2000; 33: 873-7.
14. Lee JG, Leung JW, Baillie J, Layfield LJ, Cotton PB. Benign, dysplastic, or malignant - making sense of endoscopic bile duct brush cytology: results in 149 consecutive patients. Am J Gastroenterol 1995; 90: 722-6.
15. Selvaggi SM. Biliary brushing cytology. Cytopathology 2004; 15: 74-9.
16. Siqueira E, Schoen RE, Silverman W, et al. Detecting cholangiocancer in patients with primary sclerosing cholangitis. Gastrointest Endosc 2002; 56: 40-7.
17. Ponsioen CY, Vrouenraets SME, van Milligen de Wit AWM, et al. Value of brush cytology for dominant strictures in primary sclerosing cholangitis. Endoscopy 1999; 31: 305-9.
18. Moreno LE, Kipp B, Halling KC, et al. Advanced cytologic techniques for the detection of malignant pancreatobiliary strictures. Gastroenterology 2006; 131: 1064-72.
19. Broome U, Löfberg R, Veress B, Eriksson S. Primary sclerosing cholangitis and ulcerative colitis: evidence for increased neoplastic potential. Hepatology 1995; 40: 570-7.
20. Bjorö K, Schrumpf E. Liver transplantation for primary sclerosing cholangitis. J Hepatol 2004; 40: 570-7.
21. Reddy SB, Patel T. Current approaches to the diagnosis and treatment of cholangiocancer. Curr Gastroenterol Rep 2006; 8: 30-7.
22. Nehls O, Gregor M, Klump B. Serum and bile markers for cholangiocancer. Semin Liver Dis 2004; 24: 139-54.