메뉴 건너뛰기




Volumn 55, Issue SUPPL.1, 2012, Pages 33-38

Clinical utility of micafungin: Pharmacokinetics, dosing, use in special populations and drug interactions

Author keywords

Antifungal; Aspergillus; Candida; Echinocandin; Micafungin; Pharmacokinetics

Indexed keywords

ANIDULAFUNGIN; CASPOFUNGIN; CREATININE; CYCLOSPORIN; FLUCONAZOLE; ITRACONAZOLE; MICAFUNGIN; MYCOPHENOLIC ACID; NIFEDIPINE; PREDNISOLONE; RAPAMYCIN; TACROLIMUS; VORICONAZOLE;

EID: 84859410881     PISSN: 09337407     EISSN: 14390507     Source Type: Journal    
DOI: 10.1111/j.1439-0507.2011.02114.x     Document Type: Article
Times cited : (2)

References (41)
  • 1
    • 0141863188 scopus 로고    scopus 로고
    • Echinocandin antifungal drugs
    • Denning DW. Echinocandin antifungal drugs. Lancet 2003; 362: 1142-51.
    • (2003) Lancet , vol.362 , pp. 1142-1151
    • Denning, D.W.1
  • 2
    • 0036093584 scopus 로고    scopus 로고
    • Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits
    • Petraitis V, Petraitiene R, Groll AH et al. Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits. Antimicrob Agents Chemother 2002; 46: 1857-69.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1857-1869
    • Petraitis, V.1    Petraitiene, R.2    Groll, A.H.3
  • 3
    • 33748569923 scopus 로고    scopus 로고
    • Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis
    • Denning DW, Marr KA, Lau WM et al. Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis. J Infect 2006; 53: 337-49.
    • (2006) J Infect , vol.53 , pp. 337-349
    • Denning, D.W.1    Marr, K.A.2    Lau, W.M.3
  • 4
    • 34848928703 scopus 로고    scopus 로고
    • Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis
    • Pappas PG, Rotstein CM, Betts RF et al. Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis. Clin Infect Dis 2007; 45: 883-93.
    • (2007) Clin Infect Dis , vol.45 , pp. 883-893
    • Pappas, P.G.1    Rotstein, C.M.2    Betts, R.F.3
  • 5
    • 0037130295 scopus 로고    scopus 로고
    • From natural products to clinically useful antifungals
    • Barrett D. From natural products to clinically useful antifungals. Biochim Biophys Acta 2002; 1587: 224-33.
    • (2002) Biochim Biophys Acta , vol.1587 , pp. 224-233
    • Barrett, D.1
  • 6
    • 84859393822 scopus 로고    scopus 로고
    • Highlights of prescribing information
    • Astellas P. Highlights of prescribing information.
    • Astellas, P.1
  • 7
    • 25444513384 scopus 로고    scopus 로고
    • Pharmacokinetics of micafungin in healthy volunteers, volunteers with moderate liver disease, and volunteers with renal dysfunction
    • Hebert MF, Smith HE, Marbury TC et al. Pharmacokinetics of micafungin in healthy volunteers, volunteers with moderate liver disease, and volunteers with renal dysfunction. J Clin Pharmacol 2005; 45: 1145-52.
    • (2005) J Clin Pharmacol , vol.45 , pp. 1145-1152
    • Hebert, M.F.1    Smith, H.E.2    Marbury, T.C.3
  • 9
    • 34948887165 scopus 로고    scopus 로고
    • Population pharmacokinetics of micafungin in pediatric patients and implications for antifungal dosing
    • Hope WW, Seibel NL, Schwartz CL et al. Population pharmacokinetics of micafungin in pediatric patients and implications for antifungal dosing. Antimicrob Agents Chemother 2007; 51: 3714-9.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3714-3719
    • Hope, W.W.1    Seibel, N.L.2    Schwartz, C.L.3
  • 10
    • 77952633470 scopus 로고    scopus 로고
    • Population pharmacokinetics of micafungin in neonates and young infants
    • Hope WW, Smith PB, Arrieta A et al. Population pharmacokinetics of micafungin in neonates and young infants. Antimicrob Agents Chemother 2007; 54: 2633-7.
    • (2007) Antimicrob Agents Chemother , vol.54 , pp. 2633-2637
    • Hope, W.W.1    Smith, P.B.2    Arrieta, A.3
  • 11
    • 0035185714 scopus 로고    scopus 로고
    • Compartmental pharmacokinetics and tissue distribution of the antifungal echinocandin lipopeptide micafungin (FK463) in rabbits
    • Groll AH, Mickiene D, Petraitis V et al. Compartmental pharmacokinetics and tissue distribution of the antifungal echinocandin lipopeptide micafungin (FK463) in rabbits. Antimicrob Agents Chemother 2001; 45: 3322-7.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 3322-3327
    • Groll, A.H.1    Mickiene, D.2    Petraitis, V.3
  • 12
    • 39349084676 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates
    • Hope WW, Mickiene D, Petraitis V et al. The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates. J Infect Dis 2008; 197: 163-71.
    • (2008) J Infect Dis , vol.197 , pp. 163-171
    • Hope, W.W.1    Mickiene, D.2    Petraitis, V.3
  • 13
    • 72849119258 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of repeat-dose micafungin in young infants
    • Benjamin DK Jr, Smith PB, Arrieta A et al. Safety and pharmacokinetics of repeat-dose micafungin in young infants. Clin Pharmacol Ther 2001; 87: 93-99.
    • (2001) Clin Pharmacol Ther , vol.87 , pp. 93-99
    • Benjamin Jr, D.K.1    Smith, P.B.2    Arrieta, A.3
  • 14
    • 67649559611 scopus 로고    scopus 로고
    • Pharmacokinetics of an elevated dosage of micafungin in premature neonates
    • Smith PB, Walsh TJ, Hope W et al. Pharmacokinetics of an elevated dosage of micafungin in premature neonates. Pediatr Infect Dis J 2009; 28: 412-5.
    • (2009) Pediatr Infect Dis J , vol.28 , pp. 412-415
    • Smith, P.B.1    Walsh, T.J.2    Hope, W.3
  • 15
    • 62949093915 scopus 로고    scopus 로고
    • Bronchopulmonary disposition of micafungin in healthy adult volunteers
    • Nicasio AM, Tessier PR, Nicolau DP et al. Bronchopulmonary disposition of micafungin in healthy adult volunteers. Antimicrob Agents Chemother 2009; 53: 1218-20.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1218-1220
    • Nicasio, A.M.1    Tessier, P.R.2    Nicolau, D.P.3
  • 16
    • 77955380693 scopus 로고    scopus 로고
    • Intrapulmonary pharmacokinetics and pharmacodynamics of micafungin in adult lung transplant patients
    • Walsh TJ, Goutelle S, Jelliffe RW et al. Intrapulmonary pharmacokinetics and pharmacodynamics of micafungin in adult lung transplant patients. Antimicrob Agents Chemother 2010; 54: 3451-9.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 3451-3459
    • Walsh, T.J.1    Goutelle, S.2    Jelliffe, R.W.3
  • 17
    • 8744314133 scopus 로고    scopus 로고
    • Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantation
    • van Burik JA, Ratanatharathorn V, Stepan DE et al. Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantation. Clin Infect Dis 2004; 39: 1407-16.
    • (2004) Clin Infect Dis , vol.39 , pp. 1407-1416
    • van Burik, J.A.1    Ratanatharathorn, V.2    Stepan, D.E.3
  • 19
    • 84855448583 scopus 로고    scopus 로고
    • Distribution of micafungin in the tissue fluids of patients with invasive fungal infections
    • Yamada N, Kumada K, Kishino S, Mochizuki N, Ohno K, Ogura S. Distribution of micafungin in the tissue fluids of patients with invasive fungal infections. J Infect Chemother 2011; 17: 731-4.
    • (2011) J Infect Chemother , vol.17 , pp. 731-734
    • Yamada, N.1    Kumada, K.2    Kishino, S.3    Mochizuki, N.4    Ohno, K.5    Ogura, S.6
  • 20
    • 80054856394 scopus 로고    scopus 로고
    • Intraocular penetration of micafungin in patient with Candida albicans endophthalmitis
    • Mochizuki K, Suemori S, Udo K et al. Intraocular penetration of micafungin in patient with Candida albicans endophthalmitis. J Ocul Pharmacol Ther 2011; 27: 531-3.
    • (2011) J Ocul Pharmacol Ther , vol.27 , pp. 531-533
    • Mochizuki, K.1    Suemori, S.2    Udo, K.3
  • 22
    • 54049088997 scopus 로고    scopus 로고
    • In vivo pharmacodynamic target investigation for micafungin against Candida albicans and C. glabrata in a neutropenic murine candidiasis model
    • Andes DR, Diekema DJ, Pfaller MA, Marchillo K, Bohrmueller J. In vivo pharmacodynamic target investigation for micafungin against Candida albicans and C. glabrata in a neutropenic murine candidiasis model. Antimicrob Agents Chemother 2008; 52: 3497-503.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3497-3503
    • Andes, D.R.1    Diekema, D.J.2    Pfaller, M.A.3    Marchillo, K.4    Bohrmueller, J.5
  • 23
    • 28844486224 scopus 로고    scopus 로고
    • Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activity
    • Louie A, Deziel M, Liu W, Drusano MF, Gumbo T, Drusano GL. Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activity. Antimicrob Agents Chemother 2005; 49: 5058-68.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 5058-5068
    • Louie, A.1    Deziel, M.2    Liu, W.3    Drusano, M.F.4    Gumbo, T.5    Drusano, G.L.6
  • 25
    • 80052836823 scopus 로고    scopus 로고
    • Pharmacodynamics of echinocandins against Candida glabrata: requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts
    • Howard SJ, Slater J, Sharp A et al. Pharmacodynamics of echinocandins against Candida glabrata: requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts. Antimicrob Agents Chemother 2011; 55: 4880-7.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 4880-4887
    • Howard, S.J.1    Slater, J.2    Sharp, A.3
  • 26
    • 23044471740 scopus 로고    scopus 로고
    • Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates
    • Park S, Kelly R, Kahn JN et al. Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. Antimicrob Agents Chemother 2005; 49: 3264-73.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3264-3273
    • Park, S.1    Kelly, R.2    Kahn, J.N.3
  • 28
    • 79959192938 scopus 로고    scopus 로고
    • Disseminated candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin
    • Slater JL, Howard SJ, Sharp A et al. Disseminated candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin. Antimicrob Agents Chemother 2011; 55: 3075-83.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3075-3083
    • Slater, J.L.1    Howard, S.J.2    Sharp, A.3
  • 29
    • 16244367425 scopus 로고    scopus 로고
    • Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant
    • Hiemenz J, Cagnoni P, Simpson D et al. Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant. Antimicrob Agents Chemother 2005; 49: 1331-6.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1331-1336
    • Hiemenz, J.1    Cagnoni, P.2    Simpson, D.3
  • 30
    • 33745252558 scopus 로고    scopus 로고
    • A study to determine the safety profile and maximum tolerated dose of micafungin (FK463) in patients undergoing haematopoietic stem cell transplantation
    • Sirohi B, Powles RL, Chopra R et al. A study to determine the safety profile and maximum tolerated dose of micafungin (FK463) in patients undergoing haematopoietic stem cell transplantation. Bone Marrow Transplant 2006; 38: 47-51.
    • (2006) Bone Marrow Transplant , vol.38 , pp. 47-51
    • Sirohi, B.1    Powles, R.L.2    Chopra, R.3
  • 31
    • 60549098868 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America
    • Pappas PG, Kauffman CA, Andes D et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009; 48: 503-35.
    • (2009) Clin Infect Dis , vol.48 , pp. 503-535
    • Pappas, P.G.1    Kauffman, C.A.2    Andes, D.3
  • 32
    • 33845412802 scopus 로고    scopus 로고
    • The pharmacokinetics and safety of micafungin, a novel echinocandin, in premature infants
    • Heresi GP, Gerstmann DR, Reed MD et al. The pharmacokinetics and safety of micafungin, a novel echinocandin, in premature infants. Pediatr Infect Dis J 2006; 25: 1110-5.
    • (2006) Pediatr Infect Dis J , vol.25 , pp. 1110-1115
    • Heresi, G.P.1    Gerstmann, D.R.2    Reed, M.D.3
  • 33
    • 23044445767 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of Micafungin (FK463) in febrile neutropenic pediatric patients
    • Seibel NL, Schwartz C, Arrieta A et al. Safety, tolerability, and pharmacokinetics of Micafungin (FK463) in febrile neutropenic pediatric patients. Antimicrob Agents Chemother 2005; 49: 3317-24.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3317-3324
    • Seibel, N.L.1    Schwartz, C.2    Arrieta, A.3
  • 34
    • 33847652168 scopus 로고    scopus 로고
    • Once-weekly micafungin therapy is as effective as daily therapy for disseminated candidiasis in mice with persistent neutropenia
    • Gumbo T, Drusano GL, Liu W et al. Once-weekly micafungin therapy is as effective as daily therapy for disseminated candidiasis in mice with persistent neutropenia. Antimicrob Agents Chemother 2007; 51: 968-74.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 968-974
    • Gumbo, T.1    Drusano, G.L.2    Liu, W.3
  • 35
    • 77956287727 scopus 로고    scopus 로고
    • Alternate-day micafungin antifungal prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation: a pharmacokinetic study
    • Mehta PA, Vinks AA, Filipovich A et al. Alternate-day micafungin antifungal prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation: a pharmacokinetic study. Biol Blood Marrow Transplant 2010; 16: 1458-62.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1458-1462
    • Mehta, P.A.1    Vinks, A.A.2    Filipovich, A.3
  • 36
    • 23044451114 scopus 로고    scopus 로고
    • Concomitant cyclosporine and micafungin pharmacokinetics in healthy volunteers
    • Hebert MF, Townsend RW, Austin S et al. Concomitant cyclosporine and micafungin pharmacokinetics in healthy volunteers. J Clin Pharmacol 2005; 45: 954-60.
    • (2005) J Clin Pharmacol , vol.45 , pp. 954-960
    • Hebert, M.F.1    Townsend, R.W.2    Austin, S.3
  • 37
    • 23944447575 scopus 로고    scopus 로고
    • Concomitant tacrolimus and micafungin pharmacokinetics in healthy volunteers
    • Hebert MF, Blough DK, Townsend RW et al. Concomitant tacrolimus and micafungin pharmacokinetics in healthy volunteers. J Clin Pharmacol 2005; 45: 1018-24.
    • (2005) J Clin Pharmacol , vol.45 , pp. 1018-1024
    • Hebert, M.F.1    Blough, D.K.2    Townsend, R.W.3
  • 38
    • 77956478942 scopus 로고    scopus 로고
    • Micafungin does not influence the concentration of tacrolimus in patients after allogeneic hematopoietic stem cell transplantation
    • Fukuoka N, Imataki O, Ohnishi H et al. Micafungin does not influence the concentration of tacrolimus in patients after allogeneic hematopoietic stem cell transplantation. Transplant Proc 2010; 42: 2725-30.
    • (2010) Transplant Proc , vol.42 , pp. 2725-2730
    • Fukuoka, N.1    Imataki, O.2    Ohnishi, H.3
  • 39
    • 0037629905 scopus 로고    scopus 로고
    • Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin
    • Petraitis V, Petraitiene R, Sarafandi AA et al. Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin. J Infect Dis 2003; 187: 1834-43.
    • (2003) J Infect Dis , vol.187 , pp. 1834-1843
    • Petraitis, V.1    Petraitiene, R.2    Sarafandi, A.A.3
  • 40
    • 33846602206 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of micafungin and voriconazole after separate and concomitant dosing in healthy adults
    • Keirns J, Sawamoto T, Holum M, Buell D, Wisemandle W, Alak A. Steady-state pharmacokinetics of micafungin and voriconazole after separate and concomitant dosing in healthy adults. Antimicrob Agents Chemother 2007; 51: 787-90.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 787-790
    • Keirns, J.1    Sawamoto, T.2    Holum, M.3    Buell, D.4    Wisemandle, W.5    Alak, A.6
  • 41
    • 78650820590 scopus 로고    scopus 로고
    • Lack of Pharmacokinetic Drug Interaction Between Oral Posaconazole and Caspofungin or Micafungin
    • Krishna G, Vickery D, Ma L et al. Lack of Pharmacokinetic Drug Interaction Between Oral Posaconazole and Caspofungin or Micafungin. J Clin Pharmacol 2011; 51: 84-92.
    • (2011) J Clin Pharmacol , vol.51 , pp. 84-92
    • Krishna, G.1    Vickery, D.2    Ma, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.