Mechanism of binding of NO to soluble guanylyl cyclase: Implication for the second NO binding to the heme proximal site

Biochemistry

Volumn 51, Issue 13, 2012, Pages 2737-2746

  Martin, Emil ^a   Berka, Vladimir ^a   Sharina, Iraida ^a   Tsai, Ah Lim ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING MECHANISMS; COMPUTER MODELING; CONCERTED MECHANISM; CYTOCHROME C; GUANYLYL CYCLASE; KEY ENZYMES; LINEAR DEPENDENCE; N-O COMPLEXES; NO BINDING; NO CONCENTRATION; NO MOLECULE; SECOND MESSENGER; SOLUBLE GUANYLYL CYCLASE (SGC);

LIGANDS; MAGNETIC RESONANCE; NITRIC OXIDE; PARAMAGNETISM; SIGNAL TRANSDUCTION;

PORPHYRINS;

CYTOCHROME C; FERROCHELATASE; GUANYLATE CYCLASE; HEME; LIGAND; NITRIC OXIDE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; CELL LINE; COMPUTER SIMULATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME ACTIVATION; GUANYLATE CYCLASE; HEME; KINETICS; NITRIC OXIDE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SPODOPTERA;

EID: 84859404668     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300105s     Document Type: Article

References (28)

1. Zhao, Y., Schelvis, J. P., Babcock, G. T., and Marletta, M. A. (1998) Identification of histidine 105 in the β1 subunit of soluble guanylate cyclase as the heme proximal ligand Biochemistry 37, 4502-4509
2. Poulos, T. L. (2006) Soluble guanylate cyclase Curr. Opin. Struct. Biol. 16, 736-743
3. Derbyshire, E. R. and Marletta, M. A. (2009) Biochemistry of soluble guanylate cyclase Handb. Exp. Pharmacol. 17-31
4. Zhao, Y., Brandish, P. E., Ballou, D. P., and Marletta, M. A. (1999) A molecular basis for nitric oxide sensing by soluble guanylate cyclase Proc. Natl. Acad. Sci. U.S.A. 96, 14753-14758
5. Lawson, D. M., Stevenson, C. E., Andrew, C. R., and Eady, R. R. (2000) Unprecedented proximal binding of nitric oxide to heme: Implications for guanylate cyclase EMBO J. 19, 5661-5671
6. Hough, M. A., Antonyuk, S. V., Barbieri, S., Rustage, N., McKay, A. L., Servid, A. E., Eady, R. R., Andrew, C. R., and Hasnain, S. S. (2011) Distal-to-proximal NO conversion in hemoproteins: The role of the proximal pocket J. Mol. Biol. 405, 395-409
7. Russwurm, M. and Koesling, D. (2004) NO activation of guanylyl cyclase EMBO J. 23, 4443-4450
8. Sayed, N., Baskaran, P., Ma, X., van den Akker, F., and Beuve, A. (2007) Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation Proc. Natl. Acad. Sci. U.S.A. 104, 12312-12317
9. Russwurm, M. and Koesling, D. (2004) Guanylyl cyclase: NO hits its target Biochem. Soc. Symp. 51-63
10. Cary, S. P., Winger, J. A., Derbyshire, E. R., and Marletta, M. A. (2006) Nitric oxide signaling: No longer simply on or off Trends Biochem. Sci. 31, 231-239
11. Fernhoff, N. B., Derbyshire, E. R., and Marletta, M. A. (2009) A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase Proc. Natl. Acad. Sci. U.S.A. 106, 21602-21607
12. Kharitonov, V. G., Sundquist, A. R., and Sharma, V. S. (1995) Kinetics of nitrosation of thiols by nitric oxide in the presence of oxygen J. Biol. Chem. 270, 28158-28164
13. Martin, E., Berka, V., Tsai, A.-L., and Murad, F. (2005) Soluble guanylyl cyclase: The nitric oxide receptor Methods Enzymol. 396, 478-492
14. Feelisch, M. and Noack, E. A. (1987) Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase Eur. J. Pharmacol. 139, 19-30
15. Wu, G., Lu, J. M., van der Donk, W. A., Kulmacz, R. J., and Tsai, A.-L. (2011) Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects J. Inorg. Biochem. 105, 382-390
16. Tsai, A.-L., Berka, V., Kulmacz, R. J., Wu, G., and Palmer, G. (1998) An improved sample packing device for rapid freeze-trap electron paramagnetic resonance spectroscopy kinetic measurements Anal. Biochem. 264, 165-171
17. Tsai, A.-L., Berka, V., Martin, F. E., Ma, X., van den Akker, F., Fabian, M., and Olson, J. S. (2010) Is Nostoc H-NOX an NO sensor or redox switch? Biochemistry 49, 6587-6599
18. Wei, C., Kulmacz, R. J., and Tsai, A.-L. (1995) Comparison of branched-chain and tightly coupled reaction mechanisms for prostaglandin H synthase Biochemistry 34, 8499-8512
19. 2 by Heme Protein Sensors Biochemistry 51, 172-186
20. Tsai, A.-L., Berka, V., Sharina, I., and Martin, E. (2011) Dynamic ligand exchange in soluble guanylyl cyclase: Implications for sGC regulation and desensitization J. Biol. Chem. 286, 43182-43192
21. Makino, R., Matsuda, H., Obayashi, E., Shiro, Y., Iizuka, T., and Hori, H. (1999) EPR characterization of axial bond in metal center of native and cobalt-substituted guanylate cyclase J. Biol. Chem. 274, 7714-7723
22. 2 in Low-Temperature Solutions J. Am. Chem. Soc. 122, 6516-6517
23. Andrew, C. R., Green, E. L., Lawson, D. M., and Eady, R. R. (2001) Resonance Raman studies of cytochrome c′ support the binding of NO and CO to opposite sides of the heme: Implications for ligand discrimination in heme-based sensors Biochemistry 40, 4115-4122
24. Kruglik, S. G., Lambry, J. C., Cianetti, S., Martin, J. L., Eady, R. R., Andrew, C. R., and Negrerie, M. (2007) Molecular basis for nitric oxide dynamics and affinity with Alcaligenes xylosoxidans cytochrome c J. Biol. Chem. 282, 5053-5062
25. Kharitonov, V. G., Sharma, V. S., Magde, D., and Koesling, D. (1997) Kinetics of nitric oxide dissociation from five- and six-coordinate nitrosyl hemes and heme proteins, including soluble guanylate cyclase Biochemistry 36, 6814-6818
26. Martin, E., Berka, V., Bogatenkova, E., Murad, F., and Tsai, A.-L. (2006) Ligand selectivity of soluble guanylyl cyclase: Effect of the hydrogen bonding tyrosine in the distal heme pocket on binding of oxygen, nitric oxide and carbon monoxide J. Biol. Chem. 281, 27836-27845
27. Brandish, P. E., Buechler, W., and Marletta, M. A. (1998) Regeneration of the ferrous heme of soluble guanylate cyclase from the nitric oxide complex: Acceleration by thiols and oxyhemoglobin Biochemistry 37, 16898-16907
28. Kharitonov, V. G., Russwurm, M., Magde, D., Sharma, V. S., and Koesling, D. (1997) Dissociation of nitric oxide from soluble guanylate cyclase Biochem. Biophys. Res. Commun. 239, 284-286