Crystallization of microparticulate pure polymorphs of active pharmaceutical ingredients using CO 2-expanded solvents

Crystal Growth and Design

Volumn 12, Issue 4, 2012, Pages 1717-1726

  Sala, Santiago ^a   Córdoba, Alba ^a   Moreno Calvo, Evelyn ^a   Elizondo, Elisa ^a   Muntó, Maria ^a   Rojas, Paula Elena ^a   Larrayoz, Maria Àngels ^b   Ventosa, Nora ^a   Veciana, Jaume ^a  

^a CSIC   (Spain)

^b UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL SALICYLIC ACID; ACTIVE PHARMACEUTICAL INGREDIENTS; DEPRESSURIZATIONS; EXPANDED LIQUID; EXPANDED SOLVENTS; GOOD MANUFACTURING PRACTICES; HIGH CRYSTALLINITY; INITIAL SOLUTION; MODEL DRUGS; NAPROXENS; ORGANIC SOLUTIONS; PHARMACEUTICAL INDUSTRY; POTENTIAL APPLICATIONS; PROCESS PARAMETERS; RESIDUAL SOLVENTS; SUPERSATURATION RATIO;

PARTICLE SIZE ANALYSIS; SOLVENTS;

CARBON DIOXIDE;

EID: 84859404122     PISSN: 15287483     EISSN: 15287505     Source Type: Journal    
DOI: 10.1021/cg200356x     Document Type: Article

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