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Volumn 23, Issue 7, 2012, Pages 1243-1253

Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; INTERMEDIATE FILAMENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; PROTEIN SYNEMIN; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

EID: 84859398214     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-08-0685     Document Type: Article
Times cited : (31)

References (65)
  • 2
    • 37649024728 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner
    • Andrabi S, Gjoerup OV, Kean JA, Roberts TM, Schaffhausen B (2007). Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner. Proc Natl Acad Sci USA 104, 19011-19016.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19011-19016
    • Andrabi, S.1    Gjoerup, O.V.2    Kean, J.A.3    Roberts, T.M.4    Schaffhausen, B.5
  • 3
    • 27944448894 scopus 로고    scopus 로고
    • Involvement of PP2A in viral and cellular transformation
    • DOI 10.1038/sj.onc.1209038, PII 1209038
    • Arroyo JD, Hahn WC (2005). Involvement of PP2A in viral and cellular transformation. Oncogene 24, 7746-7755. (Pubitemid 41670676)
    • (2005) Oncogene , vol.24 , Issue.52 , pp. 7746-7755
    • Arroyo, J.D.1    Hahn, W.C.2
  • 4
    • 53649106357 scopus 로고    scopus 로고
    • Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways
    • Bayascas JR (2008). Dissecting the role of the 3-phosphoinositide- dependent protein kinase-1 (PDK1) signalling pathways. Cell Cycle 7, 2978-2982.
    • (2008) Cell Cycle , vol.7 , pp. 2978-2982
    • Bayascas, J.R.1
  • 5
    • 0023917654 scopus 로고
    • A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay
    • Baykov AA, Evtushenko OA, Avaeva SM (1988). A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Anal Biochem 171, 266-270.
    • (1988) Anal Biochem , vol.171 , pp. 266-270
    • Baykov, A.A.1    Evtushenko, O.A.2    Avaeva, S.M.3
  • 6
    • 59149091041 scopus 로고    scopus 로고
    • Curcumin disrupts the mammalian target of rapamycin-raptor complex
    • Beevers CS, Chen L, Liu L, Luo Y, Webster NJ, Huang S (2009). Curcumin disrupts the mammalian target of rapamycin-raptor complex. Cancer Res 69, 1000-1008.
    • (2009) Cancer Res , vol.69 , pp. 1000-1008
    • Beevers, C.S.1    Chen, L.2    Liu, L.3    Luo, Y.4    Webster, N.J.5    Huang, S.6
  • 7
    • 0035943673 scopus 로고    scopus 로고
    • Synemin may function to directly link muscle cell intermediate filaments to both myofibrillar Z-lines and costameres
    • Bellin RM, Huiatt TW, Critchley DR, Robson RM (2001). Synemin may function to directly link muscle cell intermediate filaments to both myofibrillar Z-lines and costameres. J Biol Chem 276, 32330-3233.
    • (2001) J Biol Chem , vol.276 , pp. 32330-33233
    • Bellin, R.M.1    Huiatt, T.W.2    Critchley, D.R.3    Robson, R.M.4
  • 8
    • 0032878518 scopus 로고    scopus 로고
    • Molecular characteristics and interactions of the intermediate filament protein synemin. Interactions with alpha-actinin may anchor synemin-containing heterofilaments
    • Bellin RM, Sernett SW, Becker B, Ip W, Huiatt TW, Robson RM (1999). Molecular characteristics and interactions of the intermediate filament protein synemin. Interactions with alpha-actinin may anchor synemin-containing heterofilaments. J Biol Chem 274, 29493-29499.
    • (1999) J Biol Chem , vol.274 , pp. 29493-29499
    • Bellin, R.M.1    Sernett, S.W.2    Becker, B.3    Ip, W.4    Huiatt, T.W.5    Robson, R.M.6
  • 9
    • 33745150087 scopus 로고    scopus 로고
    • The intricacies of p21 phosphorylation: Protein/protein interactions, subcellular localization and stability
    • Child ES, Mann DJ (2006). The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability. Cell Cycle 5, 1313-1319. (Pubitemid 43894287)
    • (2006) Cell Cycle , vol.5 , Issue.12 , pp. 1313-1319
    • Child, E.S.1    Mann, D.J.2
  • 13
    • 0034088846 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease
    • DOI 10.1074/jbc.275.8.5535
    • Gong CX, Lidsky T, Wegiel J, Zuck L, Grundke-Iqbal I, Iqbal K (2000). Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease. J Biol Chem 275, 5535-5544. (Pubitemid 30115189)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.8 , pp. 5535-5544
    • Gong, C.-X.1    Lidsky, T.2    Wegiel, J.3    Zuck, L.4    Grundke-Iqbal, I.5    Iqbal, K.6
  • 14
    • 0021676702 scopus 로고
    • Expression of the intermediate-filament-associated protein synemin in chicken lens cells
    • Granger BL, Lazarides E (1984). Expression of the intermediate-filament- associated protein synemin in chicken lens cells. Mol Cell Biol 4, 1943-1950. (Pubitemid 15209965)
    • (1984) Molecular and Cellular Biology , vol.4 , Issue.10 , pp. 1943-1950
    • Granger, B.L.1    Lazarides, E.2
  • 15
    • 36049005571 scopus 로고    scopus 로고
    • Molecular evolution of type VI intermediate filament proteins
    • Guérette D, Khan PA, Savard PE, Vincent M (2007). Molecular evolution of type VI intermediate filament proteins. BMC Evol Biol 7, 164.
    • (2007) BMC Evol Biol , vol.7 , pp. 164
    • Guérette, D.1    Khan, P.A.2    Savard, P.E.3    Vincent, M.4
  • 16
    • 10744230626 scopus 로고    scopus 로고
    • Characterization of mammalian synemin, an intermediate filament protein present in all four classes of muscle cells and some neuroglial cells: Co-localization and interaction with type III intermediate filament proteins and keratins
    • DOI 10.1007/s00441-003-0732-2
    • Hirako Y, Yamakawa H, Tsujimura Y, Nishizawa Y, Okumura M, Usukura J, Matsumoto H, Jackson KW, Owaribe K, Ohara O (2003). Characterization of mammalian synemin, an intermediate filament protein present in all four classes of muscle cells and some neuroglial cells: co-localization and interaction with type III intermediate filament proteins and keratins. Cell Tissue Res 313, 195-207. (Pubitemid 37129951)
    • (2003) Cell and Tissue Research , vol.313 , Issue.2 , pp. 195-207
    • Hirako, Y.1    Yamakawa, H.2    Tsujimura, Y.3    Nishizawa, Y.4    Okumura, M.5    Usukura, J.6    Matsumoto, H.7    Jackson, K.W.8    Owaribe, K.9    Ohara, O.10
  • 17
    • 27844444696 scopus 로고    scopus 로고
    • PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility
    • DOI 10.1038/sj.emboj.7600847, PII 7600847
    • Ivaska J, Vuoriluoto K, Huovinen T, Izawa I, Inagaki M, Parker PJ (2005). PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility. EMBO J 24, 3834-3845. (Pubitemid 41637991)
    • (2005) EMBO Journal , vol.24 , Issue.22 , pp. 3834-3845
    • Ivaska, J.1    Vuoriluoto, K.2    Huovinen, T.3    Izawa, I.4    Inagaki, M.5    Parker, P.J.6
  • 18
    • 77953230609 scopus 로고    scopus 로고
    • Synemin isoforms in astroglial and neuronal cells from human central nervous system
    • Izmiryan A, Peltekian E, Paulin D, Li ZL, Xue ZG (2010). Synemin isoforms in astroglial and neuronal cells from human central nervous system. Neurochem Res 35, 881-887.
    • (2010) Neurochem Res , vol.35 , pp. 881-887
    • Izmiryan, A.1    Peltekian, E.2    Paulin, D.3    Li, Z.L.4    Xue, Z.G.5
  • 19
    • 18244395587 scopus 로고    scopus 로고
    • Intermediate filament protein synemin is present in human reactive and malignant astrocytes and associates with ruffled membranes in astrocytoma cells
    • DOI 10.1002/glia.20158
    • Jing R, Pizzolato G, Robson RM, Gabbiani G, Skalli O (2005). Intermediate filament protein synemin is present in human reactive and malignant astrocytes and associates with ruffled membranes in astrocytoma cells. Glia 50, 107-120. (Pubitemid 40695265)
    • (2005) GLIA , vol.50 , Issue.2 , pp. 107-120
    • Jing, R.1    Pizzolato, G.2    Robson, R.M.3    Gabbiani, G.4    Skalli, O.5
  • 20
    • 34248168653 scopus 로고    scopus 로고
    • Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks
    • DOI 10.1242/jcs.03423
    • Jing R, Wilhelmsson U, Goodwill W, Li L, Pan Y, Pekny M, Skalli O (2007). Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks. J Cell Sci 120, 1267-1277. (Pubitemid 46711845)
    • (2007) Journal of Cell Science , vol.120 , Issue.7 , pp. 1267-1277
    • Jing, R.1    Wilhelmsson, U.2    Goodwill, W.3    Li, L.4    Pan, Y.5    Pekny, M.6    Skalli, O.7
  • 21
    • 34347374872 scopus 로고    scopus 로고
    • Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm
    • DOI 10.1101/gad.1552107
    • Kim S, Coulombe PA (2007). Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes Dev 21, 1581-1597. (Pubitemid 47026362)
    • (2007) Genes and Development , vol.21 , Issue.13 , pp. 1581-1597
    • Kim, S.1    Coulombe, P.A.2
  • 22
    • 33745003902 scopus 로고    scopus 로고
    • A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth
    • DOI 10.1038/nature04659, PII NATURE04659
    • Kim S, Wong P, Coulombe PA (2006). A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature 441, 362-365. (Pubitemid 44050202)
    • (2006) Nature , vol.441 , Issue.7091 , pp. 362-365
    • Kim, S.1    Wong, P.2    Coulombe, P.A.3
  • 24
    • 77956412905 scopus 로고    scopus 로고
    • Cytoskeletal keratin glycosylation protects epithelial tissue from injury
    • Ku NO, Toivola DM, Strnad P, Omary MB (2010). Cytoskeletal keratin glycosylation protects epithelial tissue from injury. Nat Cell Biol 12, 876-885.
    • (2010) Nat Cell Biol , vol.12 , pp. 876-885
    • Ku, N.O.1    Toivola, D.M.2    Strnad, P.3    Omary, M.B.4
  • 25
    • 38349190654 scopus 로고    scopus 로고
    • Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt
    • Kuo YC, Huang KY, Yang CH, Yang YS, Lee WY, Chiang CW (2008). Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt. J Biol Chem 283, 1882-1892.
    • (2008) J Biol Chem , vol.283 , pp. 1882-1892
    • Kuo, Y.C.1    Huang, K.Y.2    Yang, C.H.3    Yang, Y.S.4    Lee, W.Y.5    Chiang, C.W.6
  • 26
    • 73649145175 scopus 로고    scopus 로고
    • The function of p27 KIP1 during tumor development
    • Lee J, Kim SS (2009). The function of p27 KIP1 during tumor development. Exp Mol Med 41, 765-771.
    • (2009) Exp Mol Med , vol.41 , pp. 765-771
    • Lee, J.1    Kim, S.S.2
  • 27
    • 77954367131 scopus 로고    scopus 로고
    • The B56γ3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition
    • Lee TY, Lai TY, Lin SC, Wu CW, Ni IF, Yang YS, Hung LY, Law BK, Wu CC (2010). The B56γ3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition. J Biol Chem 285, 21567-21580.
    • (2010) J Biol Chem , vol.285 , pp. 21567-21580
    • Lee, T.Y.1    Lai, T.Y.2    Lin, S.C.3    Wu, C.W.4    Ni, I.F.5    Yang, Y.S.6    Hung, L.Y.7    Law, B.K.8    Wu, C.C.9
  • 28
    • 0027519717 scopus 로고
    • 3H]endothall thioanhydride binding site. Inhibitor specificity of cantharidin and ATP analogues
    • DOI 10.1016/0006-2952(93)90109-A
    • Li YM, Mackintosh C, Casida JE (1993). Protein phosphatase 2A and its [3H] cantharidin/[3H]endothall thioanhydride binding site. Inhibitor specificity of cantharidin and ATP analogues. Biochem Pharmacol 46, 1435-1443. (Pubitemid 23319314)
    • (1993) Biochemical Pharmacology , vol.46 , Issue.8 , pp. 1435-1443
    • Li, Y.-M.1    Mackintosh, C.2    Casida, J.E.3
  • 29
    • 78650798995 scopus 로고    scopus 로고
    • Expression profiles of nestin and synemin in reactive astrocytes and Müler cells following retinal injury: A comparison with glial fibrillar acidic protein and vimentin
    • Luna G, Lewis GP, Banna CD, Skalli O, Fisher SK (2010). Expression profiles of nestin and synemin in reactive astrocytes and Müler cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentin. Mol Vis 16, 2511-2523.
    • (2010) Mol Vis , vol.16 , pp. 2511-2523
    • Luna, G.1    Lewis, G.P.2    Banna, C.D.3    Skalli, O.4    Fisher, S.K.5
  • 30
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB Signaling: Navigating Downstream
    • DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
    • Manning BD, Cantley LC (2007). AKT/PKB signaling: navigating downstream. Cell 129, 1261-1274. (Pubitemid 46962095)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 31
    • 77953484480 scopus 로고    scopus 로고
    • Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition
    • Mendez MG, Kojima S, Goldman RD (2010). Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition. FASEB J 24, 1838-1851.
    • (2010) FASEB J , vol.24 , pp. 1838-1851
    • Mendez, M.G.1    Kojima, S.2    Goldman, R.D.3
  • 33
    • 77956170185 scopus 로고    scopus 로고
    • Intermediate filament dynamics and breast cancer: Aberrant promoter methylation of the synemin gene is associated with early tumor relapse
    • Noetzel E, Rose M, Sevinc E, Hilgers RD, Hartmann A, Naami A, Knühel R, Dahl E (2010). Intermediate filament dynamics and breast cancer: aberrant promoter methylation of the synemin gene is associated with early tumor relapse. Oncogene 29, 4814-4825.
    • (2010) Oncogene , vol.29 , pp. 4814-4825
    • Noetzel, E.1    Rose, M.2    Sevinc, E.3    Hilgers, R.D.4    Hartmann, A.5    Naami, A.6    Knühel, R.7    Dahl, E.8
  • 34
    • 68849111162 scopus 로고    scopus 로고
    • Toward unraveling the complexity of simple epithelial keratins in human disease
    • Omary MB, Ku NO, Strnad P, Hanada S (2009). Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest 119, 1794-1805.
    • (2009) J Clin Invest , vol.119 , pp. 1794-1805
    • Omary, M.B.1    Ku, N.O.2    Strnad, P.3    Hanada, S.4
  • 36
    • 0025103372 scopus 로고
    • Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
    • Pallas DC, Shahrik LK, Martin BL, Jaspers S, Miller TB, Brautigan DL, Roberts TM (1990). Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell 60, 167-176.
    • (1990) Cell , vol.60 , pp. 167-176
    • Pallas, D.C.1    Shahrik, L.K.2    Martin, B.L.3    Jaspers, S.4    Miller, T.B.5    Brautigan, D.L.6    Roberts, T.M.7
  • 37
    • 51349169486 scopus 로고    scopus 로고
    • Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton
    • Pan Y, Jing R, Pitre A, Williams BJ, Skalli O (2008). Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton. FASEB J 22, 3196-3206.
    • (2008) FASEB J , vol.22 , pp. 3196-3206
    • Pan, Y.1    Jing, R.2    Pitre, A.3    Williams, B.J.4    Skalli, O.5
  • 38
    • 0034791125 scopus 로고    scopus 로고
    • Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest
    • DOI 10.1128/MCB.21.21.7449-7459.2001
    • Paramio JM, Segrelles C, Ruiz S, Jorcano JL (2001). Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest. Mol Cell Biol 21, 7449-7459. (Pubitemid 32953495)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.21 , pp. 7449-7459
    • Paramio, J.M.1    Segrelles, C.2    Ruiz, S.3    Jorcano, J.L.4
  • 39
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons DW et al. (2008). An integrated genomic analysis of human glioblastoma multiforme. Science 321, 1807-1812.
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1
  • 40
    • 14644404885 scopus 로고    scopus 로고
    • Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve
    • DOI 10.1016/j.neuron.2005.01.023
    • Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, Fainzilber M (2005). Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 45, 715-726. (Pubitemid 40320706)
    • (2005) Neuron , vol.45 , Issue.5 , pp. 715-726
    • Perlson, E.1    Hanz, S.2    Ben-Yaakov, K.3    Segal-Ruder, Y.4    Seger, R.5    Fainzilber, M.6
  • 41
    • 33846542342 scopus 로고    scopus 로고
    • On the use of ratio standard curves to accurately quantitate relative changes in protein levels by Western blot
    • DOI 10.1016/j.ab.2006.11.008, PII S0003269706008153
    • Pitre A, Pan Y, Pruett S, Skalli O (2007). On the use of ratio standard curves to accurately quantitate relative changes in protein levels by Western blot. Anal Biochem 361, 305-307. (Pubitemid 46164761)
    • (2007) Analytical Biochemistry , vol.361 , Issue.2 , pp. 305-307
    • Pitre, A.1    Pan, Y.2    Pruett, S.3    Skalli, O.4
  • 42
    • 0036629336 scopus 로고    scopus 로고
    • Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice
    • Reichelt J, Magin TM (2002). Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice. J Cell Sci 115, 2639-2650. (Pubitemid 34846505)
    • (2002) Journal of Cell Science , vol.115 , Issue.13 , pp. 2639-2650
    • Reichelt, J.1    Magin, T.M.2
  • 43
    • 0036154215 scopus 로고    scopus 로고
    • Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes
    • DOI 10.1016/S0898-6568(01)00238-8, PII S0898656801002388
    • Resjö S, Göransson O, Härndahl L, Zolnierowicz S, Manganiello V, Degerman E (2002). Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes. Cell Signal 14, 231-238. (Pubitemid 34102452)
    • (2002) Cellular Signalling , vol.14 , Issue.3 , pp. 231-238
    • Resjo, S.1    Goransson, O.2    Harndahl, L.3    Zolnierowicz, S.4    Manganiello, V.5    Degerman, E.6
  • 44
    • 79956197280 scopus 로고    scopus 로고
    • Spatial regulation of Cdc55-PP2A by Zds1/Zds2 controls mitotic entry and mitotic exit in budding yeast
    • Rossio V, Yoshida S (2011). Spatial regulation of Cdc55-PP2A by Zds1/Zds2 controls mitotic entry and mitotic exit in budding yeast. J. Cell Biol 193, 445-454.
    • (2011) J. Cell Biol , vol.193 , pp. 445-454
    • Rossio, V.1    Yoshida, S.2
  • 45
    • 33750223900 scopus 로고    scopus 로고
    • A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death
    • DOI 10.1038/sj.emboj.7601366, PII 7601366
    • Sahlgren CM, Pallari HM, He T, Chou YH, Goldman RD, Eriksson JE (2006). A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death. EMBO J 25, 4808-4819. (Pubitemid 44607026)
    • (2006) EMBO Journal , vol.25 , Issue.20 , pp. 4808-4819
    • Sahlgren, C.M.1    Pallari, H.-M.2    He, T.3    Chou, Y.-H.4    Goldman, R.D.5    Eriksson, J.E.6
  • 46
    • 0029018031 scopus 로고
    • Neurofilament-associated protein phosphatase 2A: Its possible role in preserving neurofilaments in filamentous states
    • Saito T, Shima H, Osawa Y, Nagao M, Hemmings BA, Kishimoto T, Hisanaga S (1995). Neurofilament-associated protein phosphatase 2A: its possible role in preserving neurofilaments in filamentous states. Biochemistry 34, 7376-7384.
    • (1995) Biochemistry , vol.34 , pp. 7376-7384
    • Saito, T.1    Shima, H.2    Osawa, Y.3    Nagao, M.4    Hemmings, B.A.5    Kishimoto, T.6    Hisanaga, S.7
  • 47
    • 0020568847 scopus 로고
    • Purification of the intermediate filament-associated protein, synemin, from chicken smooth muscle. Studies on its physicochemical properties, interaction with desmin, and phosphorylation
    • Sandoval IV, Colaco CA, Lazarides E (1983). Purification of the intermediate filament-associated protein, synemin, from chicken smooth muscle. Studies on its physicochemical properties, interaction with desmin, and phosphorylation. J Biol Chem 258, 2568-2576. (Pubitemid 13118458)
    • (1983) Journal of Biological Chemistry , vol.258 , Issue.4 , pp. 2568-2576
    • Sandoval, I.V.1    Colaco, C.A.L.S.2    Lazarides, E.3
  • 48
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • DOI 10.1126/science.1106148
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM (2005). Phosphorylation and regulation of Akt/PKB by the Rictor-mTOR complex. Science 307, 1098-1101. (Pubitemid 40262113)
    • (2005) Science , vol.307 , Issue.5712 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 49
    • 33747840986 scopus 로고    scopus 로고
    • Synemin expression is widespread in liver fibrosis and is induced in proliferating and malignant biliary epithelial cells
    • DOI 10.1016/j.humpath.2006.04.017, PII S0046817706002619
    • Schmitt-Graeff A, Jing R, Nitschke R, Desmoulière A, Skalli O (2006). Synemin expression is widespread in liver fibrosis and is induced in proliferating and malignant biliary epithelial cells. Hum Pathol 37, 1200-1210. (Pubitemid 44286988)
    • (2006) Human Pathology , vol.37 , Issue.9 , pp. 1200-1210
    • Schmitt-Graeff, A.1    Jing, R.2    Nitschke, R.3    Desmouliere, A.4    Skalli, O.5
  • 50
    • 70350340056 scopus 로고    scopus 로고
    • Serine/threonine phosphatases: Mechanism through structure
    • Shi Y (2009). Serine/threonine phosphatases: mechanism through structure. Cell 139, 468-484.
    • (2009) Cell , vol.139 , pp. 468-484
    • Shi, Y.1
  • 51
    • 0028924295 scopus 로고
    • A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle
    • Sontag E, Nunbhakdi-Craig V, Bloom GS, Mumby MC (1995). A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle. J Cell Biol 128, 1131-1144.
    • (1995) J Cell Biol , vol.128 , pp. 1131-1144
    • Sontag, E.1    Nunbhakdi-Craig, V.2    Bloom, G.S.3    Mumby, M.C.4
  • 52
    • 0033520355 scopus 로고    scopus 로고
    • Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies
    • Sontag E, Nunbhakdi-Craig V, Lee G, Brandt R, Kamibayashi C, Kuret J, White CL 3rd, Mumby MC, Bloom GS (1999). Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies. J Biol Chem 274, 25490-25498.
    • (1999) J Biol Chem , vol.274 , pp. 25490-25498
    • Sontag, E.1    Nunbhakdi-Craig, V.2    Lee, G.3    Brandt, R.4    Kamibayashi, C.5    Kuret, J.6    White III, C.L.7    Mumby, M.C.8    Bloom, G.S.9
  • 53
    • 0034087208 scopus 로고    scopus 로고
    • Intermediate filament protein synemin is transiently expressed in a subset of astrocytes during development
    • Sultana S, Sernett SW, Bellin RM, Robson RM, Skalli O (2000). Intermediate filament protein synemin is transiently expressed in a subset of astrocytes during development. Glia 30, 143-153. (Pubitemid 30199428)
    • (2000) GLIA , vol.30 , Issue.2 , pp. 143-153
    • Sultana, S.1    Sernett, S.W.2    Bellin, R.M.3    Robson, R.M.4    Skalli, O.5
  • 54
    • 36849051185 scopus 로고    scopus 로고
    • From G0 to S phase: A view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway
    • DOI 10.1002/jcb.21609
    • Sun A, Bagella L, Tutton S, Romano G, Giordano A (2007). From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway. J Cell Biochem 102, 1400-1404. (Pubitemid 350223943)
    • (2007) Journal of Cellular Biochemistry , vol.102 , Issue.6 , pp. 1400-1404
    • Sun, A.1    Bagella, L.2    Tutton, S.3    Romano, G.4    Giordano, A.5
  • 55
    • 72449173327 scopus 로고    scopus 로고
    • Synemin interacts with the LIM domain protein zyxin and is essential for cell adhesion and migration
    • Sun N, Huiatt TW, Paulin D, Li Z, Robson RM (2010). Synemin interacts with the LIM domain protein zyxin and is essential for cell adhesion and migration. Exp Cell Res 316, 491-505.
    • (2010) Exp Cell Res , vol.316 , pp. 491-505
    • Sun, N.1    Huiatt, T.W.2    Paulin, D.3    Li, Z.4    Robson, R.M.5
  • 56
    • 34447275978 scopus 로고    scopus 로고
    • Small-molecule inhibitors of ser/thr protein phosphatases: Specificity, use and common forms of abuse
    • Swingle M, Ni L, Honkanen RE (2007). Small-molecule inhibitors of ser/thr protein phosphatases: specificity, use and common forms of abuse. Methods Mol Biol 365, 23-38.
    • (2007) Methods Mol Biol , vol.365 , pp. 23-38
    • Swingle, M.1    Ni, L.2    Honkanen, R.E.3
  • 57
    • 33646777438 scopus 로고    scopus 로고
    • Protein phosphatase-2A associates with and dephosphorylates keratin 8 after hyposmotic stress in a site- And cell-specific manner
    • Tao GZ, Toivola DM, Zhou Q, Strnad P, Xu B, Michie SA, Omary MB (2006). Protein phosphatase-2A associates with and dephosphorylates keratin 8 after hyposmotic stress in a site- and cell-specific manner. J Cell Sci 19, 1425-1432.
    • (2006) J Cell Sci , vol.19 , pp. 1425-1432
    • Tao, G.Z.1    Toivola, D.M.2    Zhou, Q.3    Strnad, P.4    Xu, B.5    Michie, S.A.6    Omary, M.B.7
  • 59
    • 0035180120 scopus 로고    scopus 로고
    • Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratins 8/18
    • DOI 10.1053/jhep.2001.29374
    • Toivola DM, Nieminen MI, Hesse M, He T, Baribault H, Magin TM, Omary MB, Eriksson JE (2001). Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratins 8/18. Hepatology 34, 1174-1183. (Pubitemid 33096590)
    • (2001) Hepatology , vol.34 , Issue.6 , pp. 1174-1183
    • Toivola, D.M.1    Nieminen, M.I.2    Hesse, M.3    He, T.4    Baribault, H.5    Magin, T.M.6    Omary, M.B.7    Eriksson, J.E.8
  • 60
    • 0032978487 scopus 로고    scopus 로고
    • Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55
    • Turowski P, Myles T, Hemmings BA, Fernandez A, Lamb NJ (1999). Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55. Mol Biol Cell 10, 1997-2015. (Pubitemid 29272646)
    • (1999) Molecular Biology of the Cell , vol.10 , Issue.6 , pp. 1997-2015
    • Turowski, P.1    Myles, T.2    Hemmings, B.A.3    Fernandez, A.4    Lamb, N.J.C.5
  • 61
    • 53849147183 scopus 로고    scopus 로고
    • Post-translational regulation of the tumor suppressor p27(KIP1)
    • Vervoorts J, Lüscher B (2008). Post-translational regulation of the tumor suppressor p27(KIP1). Cell Mol Life Sci 65, 3255-3264.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3255-3264
    • Vervoorts, J.1    Lüscher, B.2
  • 62
    • 61649127812 scopus 로고    scopus 로고
    • From promiscuity to precision: Protein phosphatases get a makeover
    • Virshup DM, Shenolikar S (2009). From promiscuity to precision: protein phosphatases get a makeover. Mol Cell 33, 537-545.
    • (2009) Mol Cell , vol.33 , pp. 537-545
    • Virshup, D.M.1    Shenolikar, S.2
  • 64
    • 0021828496 scopus 로고
    • Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
    • DOI 10.1038/315239a0
    • Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM (1985). Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315, 239-242. (Pubitemid 15064453)
    • (1985) Nature , vol.315 , Issue.6016 , pp. 239-242
    • Whitman, M.1    Kaplan, D.R.2    Schaffhausen, B.3


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