MUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma

International Journal of Surgical Pathology

Volumn 20, Issue 1, 2012, Pages 29-36

  Ferenczi, Katalin ^a   Lastra, Ricardo R ^a   Farkas, Tunde ^a   Elenitsas, Rosalie ^a   Xu, Xiaowei ^a   Roberts, Shelley ^a   Brooks, John S ^a   Zhang, Paul J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

immunohistochemistry; melanoma; MUM1; PEComa

Indexed keywords

INTERFERON REGULATORY FACTOR 4; MELAN A; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOCLONAL ANTIBODY HMB 45; MONOPHENOL MONOOXYGENASE; PROTEIN S 100;

ANGIOMYOLIPOMA; ARTICLE; CANCER MORPHOLOGY; CELL STRUCTURE; CLEAR CELL SARCOMA; DERMIS; DIFFERENTIAL DIAGNOSIS; EPIDERMIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; MELANOCYTE; MELANOMA; METASTASIS; PERIVASCULAR EPITHELIOID CELL TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY;

DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON REGULATORY FACTORS; MELANOMA; PERIVASCULAR EPITHELIOID CELL NEOPLASMS; RETROSPECTIVE STUDIES; SARCOMA, CLEAR CELL; TUMOR MARKERS, BIOLOGICAL;

EID: 84859386770     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896911418204     Document Type: Article

References (19)

1. Armah HB, Parwani AV. Perivascular epithelioid cell tumor. Arch Pathol Lab Med. 2009;133:648-654.
2. Martignoni G, Pea M, Reghellin D, Zamboni G, Bonetti F. PEComas: the past, the present and the future. Virchows Arch. 2008;452:119-132.
3. Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature. Am J Surg Pathol. 2005;29: 1558-1575.
4. Hornick JL, Fletcher CD. PEComa: what do we know so far? Histopathology. 2006;48:75-82.
5. Mentzel T, Reisshauer S, Rütten A, Hantschke M, Soares de Almeida LM, Kutzner H. Cutaneous clear cell myomelanocytic tumour: a new member of the growing family of perivascular epithelioid cell tumours (PEComas). Clinicopathological and immunohistochemical analysis of seven cases. Histopathology. 2005;46:498-504.
6. de Saint Aubain Somerhausen N, Gomez Galdon M, Bouffioux B, et al. Clear cell 'sugar' tumor (PEComa) of the skin: a case report. J Cutan Pathol. 2005;32:441-444. (Pubitemid 40853009)
7. Bonetti F, Pea M, Martignoni G, Zamboni G. PEC and sugar. Am J Surg Pathol. 1992;16:307-308.
8. Calder KB, Coplowitz S, Schlauder S, Morgan MB. A case series and immunophenotypic analysis of CK20-/CK7+ primary neuroendocrine carcinoma of the skin. J Cutan Pathol. 2007;34:918-923. (Pubitemid 350132010)
9. Natkunam Y, Warnke RA, Montgomery K, Falini B, van De Rijn M. Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol. 2001;14:686-694. (Pubitemid 32667213)
10. Pea M, Bonetti F, Zamboni G, Martignoni G, Fiore-Donati L, Doglioni C. Clear cell tumor and angiomyolipoma. Am J Surg Pathol. 1991;15:199-202.
11. Gal AA, Koss MN, Hochholzer L, Chejfec G. An immunohistochemical study of benign clear cell ('sugar') tumor of the lung. Arch Pathol Lab Med. 1991;115: 1034-1038.
12. Carlson JA, Dickersin GR, Sober AJ, Barnhill RL. Desmoplastic neurotropic melanoma. A clinicopathologic analysis of 28 cases. Cancer. 1995;75:478-494.
13. Riccioni L, Di Tommaso L, Collina G. Actin-rich desmoplastic malignant melanoma: report of three cases. Am J Dermatopathol. 1999;21:537-541.
14. Grossman A, Mittrücker HW, Nicholl J, et al. Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25. Genomics. 1996;37:229-233. (Pubitemid 26360897)
15. Sundram U, Harvell JD, Rouse RV, Natkunam Y. Expression of the B-cell proliferation marker MUM1 by melanocytic lesions and comparison with S100, gp100 (HMB45), and MelanA. Mod Pathol. 2003;16:802-810. (Pubitemid 37011076)
16. Falini B, Fizzotti M, Pucciarini A, et al. A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood. 2000;95:2084-2092. (Pubitemid 30151649)
17. Tsuboi K, Iida S, Inagaki H, et al. MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies. Leukemia. 2000;14:449-456. (Pubitemid 30142870)
18. Alonso SR, Ortiz P, Pollán M, Pérez-Gómez B, et al. Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study. Am J Pathol. 2004;164:193-203. (Pubitemid 38364604)
19. Stone CH, Lee MW, Amin MB, et al. Renal angiomyolipoma: further immunophenotypic characterization of an expanding morphologic spectrum. Arch Pathol Lab Med. 2001; 125:751-758. (Pubitemid 32520518)