The formation of P particle increased immunogenicity of norovirus P protein

Immunology

Volumn 136, Issue 1, 2012, Pages 28-29

  Tan, Ming ^a   Jiang, Xi ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Antigen presentation; Calicivirus; Norovirus; P domain; P particle; Vaccine; Vaccine platform

Indexed keywords

GLYCINE DEHYDROGENASE (DECARBOXYLATING); VIRUS PROTEIN;

ANTIGEN PRESENTATION; ESCHERICHIA COLI; IMMUNE RESPONSE; IMMUNOGENICITY; MOLECULAR WEIGHT; NONHUMAN; NOROVIRUS; NOTE; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; VIRUS PARTICLE;

ANIMALS; CALICIVIRIDAE INFECTIONS; FEMALE; GASTROENTERITIS; HUMANS; NOROVIRUS; VACCINES, VIRUS-LIKE PARTICLE;

EID: 84859356899     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2012.03555.x     Document Type: Note

References (16)

1. Tamminen K, Huhti L, Koho T, Lappalainen S, Hytonen VP, Vesikari T, Blazevic V. A comparison of immunogenicity of norovirus GII-4 virus-like particles and P-particles. Immunology 2012; 135:89-99.
2. Tan M, Hegde RS, Jiang X. The P domain of norovirus capsid protein forms dimer and binds to histo-blood group antigen receptors. J Virol 2004; 78:6233-42.
3. Tan M, Meller J, Jiang X. C-terminal arginine cluster is essential for receptor binding of norovirus capsid protein. J Virol 2006; 80:7322-31.
4. Bu W, Mamedova A, Tan M, Xia M, Jiang X, Hegde RS. Structural basis for the receptor binding specificity of Norwalk virus. J Virol 2008; 82:5340-7.
5. Cao S, Lou Z, Tan M et al. Structural basis for the recognition of blood group trisaccharides by norovirus. J Virol 2007; 81:5949-57.
6. Chen Y, Tan M, Xia M et al. Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens. PLoS Pathogens 2011; 7:e1002152.
7. Choi JM, Hutson AM, Estes MK, Prasad BV. Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus. Proc Natl Acad Sci U S A 2008; 105:9175-80.
8. Hansman GS, Biertumpfel C, Georgiev I, McLellan JS, Chen L, Zhou T, Katayama K, Kwong PD. Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability. J Virol 2011; 85:6687-701.
9. Shanker S, Choi JM, Sankaran B, Atmar RL, Estes MK, Prasad BV. Structural analysis of histo-blood group antigen binding specificity in a norovirus GII.4 epidemic variant: implications for epochal evolution. J Virol 2011; 85:8635-45.
10. Tan M, Fang PA, Xia M, Chachiyo T, Jiang W, Jiang X. Terminal modifications of norovirus P domain resulted in a new type of subviral particles, the small P particles. Virology 2011; 410:345-52.
11. Tan M, Fang P, Chachiyo T, Xia M, Huang P, Fang Z, Jiang W, Jiang X. Noroviral P particle: structure, function and applications in virus-host interaction. Virology 2008; 382:115-23.
12. Tan M, Huang P, Xia M et al. Norovirus P particle, a novel platform for vaccine development and antibody production. J Virol 2011; 85:753-64.
13. Tan M, Jiang X. The P domain of norovirus capsid protein forms a subviral particle that binds to histo-blood group antigen receptors. J Virol 2005; 79:14017-30.
14. Koho T, Huhti L, Blazevic V et al. Production and characterization of virus-like particles and the P domain protein of GII.4 norovirus. J Virol Methods 2012; 179:1-7.
15. Tan M, Xia M, Chen Y, Bu W, Hegde RS, Meller J, Li X, Jiang X. Conservation of carbohydrate binding interfaces: evidence of human HBGA selection in norovirus evolution. PLoS One 2009; 4:e5058.
16. Xia M, Tan M, Wei C, Zhong W, Wang L, McNeal M, Jiang X. A candidate dual vaccine against influenza and noroviruses. Vaccine 2011; 29:7670-7.