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Volumn 7, Issue 4, 2012, Pages

Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons

Author keywords

[No Author keywords available]

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; METHYLSUCCINATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SAPONIN; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; UNCLASSIFIED DRUG; 2 (2 (4 (4 NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; 2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; ANTIARRHYTHMIC AGENT; DRUG DERIVATIVE; THIOUREA;

EID: 84859356049     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034465     Document Type: Article
Times cited : (53)

References (32)
  • 1
    • 79953180902 scopus 로고    scopus 로고
    • Assessing mitochondrial dysfunction in cells
    • Brand MD, Nicholls DG, (2011) Assessing mitochondrial dysfunction in cells. Biochem J 435: 297-312.
    • (2011) Biochem J , vol.435 , pp. 297-312
    • Brand, M.D.1    Nicholls, D.G.2
  • 2
    • 4544298249 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of neural cell apoptosis
    • Polster BM, Fiskum G, (2004) Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 90: 1281-1289.
    • (2004) J Neurochem , vol.90 , pp. 1281-1289
    • Polster, B.M.1    Fiskum, G.2
  • 3
    • 0033510014 scopus 로고    scopus 로고
    • Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases
    • Fiskum G, Murphy AN, Beal MF, (1999) Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases. J Cereb Blood Flow Metab 19: 351-369.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 351-369
    • Fiskum, G.1    Murphy, A.N.2    Beal, M.F.3
  • 4
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin MT, Beal MF, (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443: 787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 5
    • 44949185670 scopus 로고    scopus 로고
    • Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells
    • Kuznetsov AV, Veksler V, Gellerich FN, Saks V, Margreiter R, et al. (2008) Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat Protoc 3: 965-976.
    • (2008) Nat Protoc , vol.3 , pp. 965-976
    • Kuznetsov, A.V.1    Veksler, V.2    Gellerich, F.N.3    Saks, V.4    Margreiter, R.5
  • 8
    • 0019324973 scopus 로고
    • The regulation of brain mitochondrial calcium-ion transport. The role of ATP in the discrimination between kinetic and membrane-potential-dependent calcium-ion efflux mechanisms
    • Nicholls DG, Scott ID, (1980) The regulation of brain mitochondrial calcium-ion transport. The role of ATP in the discrimination between kinetic and membrane-potential-dependent calcium-ion efflux mechanisms. Biochem J 186: 833-839.
    • (1980) Biochem J , vol.186 , pp. 833-839
    • Nicholls, D.G.1    Scott, I.D.2
  • 9
    • 0038143180 scopus 로고    scopus 로고
    • The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
    • Chalmers S, Nicholls DG, (2003) The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J Biol Chem 278: 19062-19070.
    • (2003) J Biol Chem , vol.278 , pp. 19062-19070
    • Chalmers, S.1    Nicholls, D.G.2
  • 10
    • 78650086750 scopus 로고    scopus 로고
    • KB-R7943, an inhibitor of the reverse Na(+)/Ca(2+) exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I
    • Brustovetsky T, Brittain MK, Sheets PL, Cummins TR, Pinelis V, et al. (2011) KB-R7943, an inhibitor of the reverse Na(+)/Ca(2+) exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I. Br J Pharmacol 162: 255-270.
    • (2011) Br J Pharmacol , vol.162 , pp. 255-270
    • Brustovetsky, T.1    Brittain, M.K.2    Sheets, P.L.3    Cummins, T.R.4    Pinelis, V.5
  • 11
    • 0031816393 scopus 로고    scopus 로고
    • Differential inhibition of Na+/Ca2+ exchanger isoforms by divalent cations and isothiourea derivative
    • Iwamoto T, Shigekawa M, (1998) Differential inhibition of Na+/Ca2+ exchanger isoforms by divalent cations and isothiourea derivative. Am J Physiol 275: C423-C430.
    • (1998) Am J Physiol , vol.275
    • Iwamoto, T.1    Shigekawa, M.2
  • 12
    • 20444386209 scopus 로고    scopus 로고
    • Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins
    • Stoica BA, Movsesyan VA, Knoblach SM, Faden AI, (2005) Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. Mol Cell Neurosci 29: 355-371.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 355-371
    • Stoica, B.A.1    Movsesyan, V.A.2    Knoblach, S.M.3    Faden, A.I.4
  • 13
    • 0035478060 scopus 로고    scopus 로고
    • Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury
    • Yakovlev AG, Ota K, Wang G, Movsesyan V, Bao WL, et al. (2001) Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury. J Neurosci 21: 7439-7446.
    • (2001) J Neurosci , vol.21 , pp. 7439-7446
    • Yakovlev, A.G.1    Ota, K.2    Wang, G.3    Movsesyan, V.4    Bao, W.L.5
  • 14
    • 67650484137 scopus 로고    scopus 로고
    • Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity
    • Gerencser AA, Mark KA, Hubbard AE, Divakaruni AS, Mehrabian Z, et al. (2009) Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity. J Neurochem 110: 990-1004.
    • (2009) J Neurochem , vol.110 , pp. 990-1004
    • Gerencser, A.A.1    Mark, K.A.2    Hubbard, A.E.3    Divakaruni, A.S.4    Mehrabian, Z.5
  • 15
    • 33846317064 scopus 로고    scopus 로고
    • Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
    • Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, et al. (2007) Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol 292: C125-C136.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Wu, M.1    Neilson, A.2    Swift, A.L.3    Moran, R.4    Tamagnine, J.5
  • 16
    • 68849085646 scopus 로고    scopus 로고
    • Quantitative microplate-based respirometry with correction for oxygen diffusion
    • Gerencser AA, Neilson A, Choi SW, Edman U, Yadava N, et al. (2009) Quantitative microplate-based respirometry with correction for oxygen diffusion. Anal Chem 81: 6868-6878.
    • (2009) Anal Chem , vol.81 , pp. 6868-6878
    • Gerencser, A.A.1    Neilson, A.2    Choi, S.W.3    Edman, U.4    Yadava, N.5
  • 17
    • 1642317185 scopus 로고    scopus 로고
    • Some precautions in using chelators to buffer metals in biological solutions
    • Patton C, Thompson S, Epel D, (2004) Some precautions in using chelators to buffer metals in biological solutions. Cell Calc 35: 427-431.
    • (2004) Cell Calc , vol.35 , pp. 427-431
    • Patton, C.1    Thompson, S.2    Epel, D.3
  • 18
    • 79955525026 scopus 로고    scopus 로고
    • Analysis of regional brain mitochondrial bioenergetics and susceptibility to mitochondrial inhibition utilizing a microplate based system
    • Sauerbeck A, Pandya J, Singh I, Bittman K, Readnower R, et al. (2011) Analysis of regional brain mitochondrial bioenergetics and susceptibility to mitochondrial inhibition utilizing a microplate based system. J Neurosci Methods 198: 36-43.
    • (2011) J Neurosci Methods , vol.198 , pp. 36-43
    • Sauerbeck, A.1    Pandya, J.2    Singh, I.3    Bittman, K.4    Readnower, R.5
  • 19
    • 77249126523 scopus 로고    scopus 로고
    • Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species
    • Dranka BP, Hill BG, Darley-Usmar VM, (2010) Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species. Free Radic Biol Med 48: 905-914.
    • (2010) Free Radic Biol Med , vol.48 , pp. 905-914
    • Dranka, B.P.1    Hill, B.G.2    Darley-Usmar, V.M.3
  • 20
    • 80053331862 scopus 로고    scopus 로고
    • Adaptation of microplate-based respirometry for hippocampal slices and analysis of respiratory capacity
    • Schuh RA, Clerc P, Hwang H, Mehrabian Z, Bittman K, et al. (2011) Adaptation of microplate-based respirometry for hippocampal slices and analysis of respiratory capacity. J Neurosci Res 89: 1979-1988.
    • (2011) J Neurosci Res , vol.89 , pp. 1979-1988
    • Schuh, R.A.1    Clerc, P.2    Hwang, H.3    Mehrabian, Z.4    Bittman, K.5
  • 21
    • 73249119801 scopus 로고    scopus 로고
    • Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport
    • Jones TT, Brewer GJ, (2010) Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport. Biochim Biophys Acta 1797: 167-176.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 167-176
    • Jones, T.T.1    Brewer, G.J.2
  • 22
    • 67649135866 scopus 로고    scopus 로고
    • Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction
    • Brustovetsky T, Li V, Brustovetsky N, (2009) Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction. Cell Calc 46: 18-29.
    • (2009) Cell Calc , vol.46 , pp. 18-29
    • Brustovetsky, T.1    Li, V.2    Brustovetsky, N.3
  • 23
    • 0035851110 scopus 로고    scopus 로고
    • BH3 death domain peptide induces cell type-selective mitochondrial outer membrane permeability
    • Polster BM, Kinnally KW, Fiskum G, (2001) BH3 death domain peptide induces cell type-selective mitochondrial outer membrane permeability. J Biol Chem 276: 37887-37894.
    • (2001) J Biol Chem , vol.276 , pp. 37887-37894
    • Polster, B.M.1    Kinnally, K.W.2    Fiskum, G.3
  • 24
    • 46349104861 scopus 로고    scopus 로고
    • Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity
    • Abramov AY, Duchen MR, (2008) Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity. Biochim Biophys Acta 1777: 953-964.
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 953-964
    • Abramov, A.Y.1    Duchen, M.R.2
  • 25
    • 0030805969 scopus 로고    scopus 로고
    • Isolation and characterization of tightly coupled mitochondria from neurons and astrocytes in primary culture
    • Almeida A, Medina JM, (1997) Isolation and characterization of tightly coupled mitochondria from neurons and astrocytes in primary culture. Brain Res 764: 167-172.
    • (1997) Brain Res , vol.764 , pp. 167-172
    • Almeida, A.1    Medina, J.M.2
  • 26
    • 33644781684 scopus 로고    scopus 로고
    • Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation
    • Kristian T, Hopkins IB, McKenna MC, Fiskum G, (2006) Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation. J Neurosci Methods 152: 136-143.
    • (2006) J Neurosci Methods , vol.152 , pp. 136-143
    • Kristian, T.1    Hopkins, I.B.2    McKenna, M.C.3    Fiskum, G.4
  • 27
    • 50249154155 scopus 로고    scopus 로고
    • Isolation of mitochondria from rat brain using Percoll density gradient centrifugation
    • Sims NR, Anderson MF, (2008) Isolation of mitochondria from rat brain using Percoll density gradient centrifugation. Nat Protoc 3: 1228-1239.
    • (2008) Nat Protoc , vol.3 , pp. 1228-1239
    • Sims, N.R.1    Anderson, M.F.2
  • 28
    • 78249257768 scopus 로고    scopus 로고
    • Mitochondrial Functional Impairment with Aging is Exaggerated in Isolated Mitochondria compared to Permeabilized Myofibers
    • Picard M, Ritchie D, Wright KJ, Romestaing C, Thomas MM, et al. (2010) Mitochondrial Functional Impairment with Aging is Exaggerated in Isolated Mitochondria compared to Permeabilized Myofibers. Aging Cell 9: 1032-1046.
    • (2010) Aging Cell , vol.9 , pp. 1032-1046
    • Picard, M.1    Ritchie, D.2    Wright, K.J.3    Romestaing, C.4    Thomas, M.M.5
  • 29
    • 79953147483 scopus 로고    scopus 로고
    • Mitochondrial structure and function are disrupted by standard isolation methods
    • Picard M, Taivassalo T, Ritchie D, Wright KJ, Thomas MM, et al. (2011) Mitochondrial structure and function are disrupted by standard isolation methods. PLoS ONE 6: e18317.
    • (2011) PLoS ONE , vol.6
    • Picard, M.1    Taivassalo, T.2    Ritchie, D.3    Wright, K.J.4    Thomas, M.M.5
  • 30
    • 70450207200 scopus 로고    scopus 로고
    • Spare respiratory capacity, oxidative stress and excitotoxicity
    • Nicholls DG, (2009) Spare respiratory capacity, oxidative stress and excitotoxicity. Biochem Soc Trans 37: 1385-1388.
    • (2009) Biochem Soc Trans , vol.37 , pp. 1385-1388
    • Nicholls, D.G.1
  • 31
    • 34347353227 scopus 로고    scopus 로고
    • The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter
    • Santo-Domingo J, Vay L, Hernandez-Sanmiguel E, Lobaton CD, Moreno A, et al. (2007) The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter. Br J Pharmacol 151: 647-654.
    • (2007) Br J Pharmacol , vol.151 , pp. 647-654
    • Santo-Domingo, J.1    Vay, L.2    Hernandez-Sanmiguel, E.3    Lobaton, C.D.4    Moreno, A.5
  • 32
    • 0024548920 scopus 로고
    • Effect of esters of succinic acid and other citric acid cycle intermediates on insulin release and inositol phosphate formation by pancreatic islets
    • Macdonald MJ, Fahien LA, Mertz RJ, Rana RS, (1989) Effect of esters of succinic acid and other citric acid cycle intermediates on insulin release and inositol phosphate formation by pancreatic islets. Arch Biochem Biophys 269: 400-406.
    • (1989) Arch Biochem Biophys , vol.269 , pp. 400-406
    • Macdonald, M.J.1    Fahien, L.A.2    Mertz, R.J.3    Rana, R.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.