-
1
-
-
0020334774
-
Pharmacokinetics, interactions with macromolecules and species differences in metabolism of DEHP
-
Albro, P.W., Corbett, J.T., Schroeder, J.L., Jordan, S., Matthews H.B. (1982): Pharmacokinetics, interactions with macromolecules and species differences in metabolism of DEHP. Environ. Health Perspect., 45,19-25.
-
(1982)
Environ. Health Perspect
, vol.45
, pp. 19-25
-
-
Albro, P.W.1
Corbett, J.T.2
Schroeder, J.L.3
Jordan, S.4
Matthews, H.B.5
-
2
-
-
79960838649
-
A twenty- olunteer study using deuterium labelling to determine the kinetics and fractional excretion of primary and secondary urinary metabolites of di-2-ethylhexylphthalate and di-iso-nonylphthalate
-
Anderson, W.A., Castle, L., Hird, S., Jeffery, J. and Scotter, M.J. (2011): A twenty- olunteer study using deuterium labelling to determine the kinetics and fractional excretion of primary and secondary urinary metabolites of di-2-ethylhexylphthalate and di-iso-nonylphthalate. Food and Chem. Toxicol., 49, 2022-2029.
-
(2011)
Food and Chem. Toxicol
, vol.49
, pp. 2022-2029
-
-
Anderson, W.A.1
Castle, L.2
Hird, S.3
Jeffery, J.4
Scotter, M.J.5
-
3
-
-
0041304143
-
-
ATSDR Atlanta, GA, Agency for Toxic Substances and Disease Registry
-
ATSDR (2002): Toxicological profile for di(2-ethylhexyl)phthalate (DEHP). Atlanta, GA, Agency for Toxic Substances and Disease Registry, 7-26-2004.
-
(2002)
Toxicological profile for di(2-ethylhexyl)phthalate (DEHP)
, pp. 7-26
-
-
-
4
-
-
0024906407
-
Metabolism of DEHP: Effects of prefeeding and dose variation, and comparative studies in rodents and the cynomolgus monkey (CMA Studies)
-
Astill, B.D. (1989): Metabolism of DEHP: Effects of prefeeding and dose variation, and comparative studies in rodents and the cynomolgus monkey (CMA Studies). Drug. Metab. Rev., 21, 35-53.
-
(1989)
Drug. Metab. Rev
, vol.21
, pp. 35-53
-
-
Astill, B.D.1
-
5
-
-
64049090287
-
Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro
-
Chauvigne, F., Menuet, A., Lesne, L., Chagnon, M.C., Chevrier, C., Regnier, J.F., Angerer, J. and Jegou, B. (2009): Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro. Environ. Health. Perspect., 117, 515-521.
-
(2009)
Environ. Health. Perspect
, vol.117
, pp. 515-521
-
-
Chauvigne, F.1
Menuet, A.2
Lesne, L.3
Chagnon, M.C.4
Chevrier, C.5
Regnier, J.F.6
Angerer, J.7
Jegou, B.8
-
6
-
-
0023751785
-
Testicular toxicity and reduced Sertoli cell numbers In neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults
-
Dostal, L.A., Chapin, R.E., Stefanski, S.A., Harris, M.W. and Schwetz, B.A. (1988): Testicular toxicity and reduced Sertoli cell numbers In neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults. Toxicol. Appl. Pharmacol., 95, 104-121.
-
(1988)
Toxicol. Appl. Pharmacol
, vol.95
, pp. 104-121
-
-
Dostal, L.A.1
Chapin, R.E.2
Stefanski, S.A.3
Harris, M.W.4
Schwetz, B.A.5
-
7
-
-
34547414129
-
Metabolism of phthalates in humans
-
Frederiksen, H., Skakkebaek, N.E. and Andersson, A.M. (2007): Metabolism of phthalates in humans. Mol. Nutr. Food Res., 51, 899-911.
-
(2007)
Mol. Nutr. Food Res
, vol.51
, pp. 899-911
-
-
Frederiksen, H.1
Skakkebaek, N.E.2
Andersson, A.M.3
-
8
-
-
0021339760
-
Effect of some phthalate esters and other testicular toxins on primary cultures of testicular cells
-
Gray, T.J. and Beamand, J.A. (1984): Effect of some phthalate esters and other testicular toxins on primary cultures of testicular cells. Food Chem. Toxicol., 22, 123-131.
-
(1984)
Food Chem. Toxicol
, vol.22
, pp. 123-131
-
-
Gray, T.J.1
Beamand, J.A.2
-
9
-
-
0022560385
-
Aspects of the testicular toxicity of phthalate esters
-
Gray, T.J. and Gangolli, S.D. (1986). Aspects of the testicular toxicity of phthalate esters. Environ. Health Perspect., 65, 229-235.
-
(1986)
Environ. Health Perspect
, vol.65
, pp. 229-235
-
-
Gray, T.J.1
Gangolli, S.D.2
-
10
-
-
0030002143
-
Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk
-
Huber, W.W., KrauppGrasl, B. and Schulte-Hermann, R. (1996): Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk. Crit. Rev. Toxicol., 26, 365-481.
-
(1996)
Crit. Rev. Toxicol
, vol.26
, pp. 365-481
-
-
Huber, W.W.1
Krauppgrasl, B.2
Schulte-Hermann, R.3
-
12
-
-
84859361647
-
Harmonized tripartite guideline
-
ICH, E6 (R1)
-
ICH (1996): Harmonized tripartite guideline. Guideline for good clinical practice. E6 (R1).
-
(1996)
Guideline For Good Clinical Practice
-
-
-
13
-
-
0036755741
-
NTP center for the evaluation of risks to human reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di(2-ethylhexyl) phthalate
-
Kavlock, R., Boekelheide, K., Chapin, R., Cunningham, M., Faustman, E., Foster, P., Golub, M., Henderson, R., Hinberg, I., Little, R., Seed, J., Shea, K., Tabacova, S., Tyl, R., Williams, P. and Zacharewski, T. (2002): NTP center for the evaluation of risks to human reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di(2-ethylhexyl) phthalate. Reprod. Toxicol., 16, 529-653.
-
(2002)
Reprod. Toxicol
, vol.16
, pp. 529-653
-
-
Kavlock, R.1
Boekelheide, K.2
Chapin, R.3
Cunningham, M.4
Faustman, E.5
Foster, P.6
Golub, M.7
Henderson, R.8
Hinberg, I.9
Little, R.10
Seed, J.11
Shea, K.12
Tabacova, S.13
Tyl, R.14
Williams, P.15
Zacharewski, T.16
-
14
-
-
8444221615
-
Neonatal exposure to di(n-butyl) phthalate (DBP) alters male reproductive-tract development
-
Kim, H.S., Kim, T.S., Shin, J.H., Moon, H.J., Kang, I.H., Kim, I.Y., Oh, J.Y. and Han, S.Y. (2004): Neonatal exposure to di(n-butyl) phthalate (DBP) alters male reproductive-tract development. J. Toxicol. Environ. Health A., 67, 2045-2060.
-
(2004)
J. Toxicol. Environ. Health A
, vol.67
, pp. 2045-2060
-
-
Kim, H.S.1
Kim, T.S.2
Shin, J.H.3
Moon, H.J.4
Kang, I.H.5
Kim, I.Y.6
Oh, J.Y.7
Han, S.Y.8
-
15
-
-
33645231471
-
Di(2-ethylhexyl) phthalate (DEHP): Human metabolism and internal exposure -- an update and latest results
-
Koch, H.M., Preuss, R. and Angerer, J. (2006): Di(2-ethylhexyl) phthalate (DEHP): human metabolism and internal exposure -- an update and latest results. Int. J. Androl., 29, 155-165.
-
(2006)
Int. J. Androl
, vol.29
, pp. 155-165
-
-
Koch, H.M.1
Preuss, R.2
Angerer, J.3
-
16
-
-
0031943086
-
Subchronic toxicity of di(2-ethylhexyl) phthalate in common marmosets: Lack of hepatic peroxisome proliferation, testicular atrophy or pancreatic acinar cell hyperplasia
-
Kurata, Y., Kidachi, F., Yokoyama, M., Toyota, N., Tsuchitani, M. and Katoh, M. (1998): Subchronic toxicity of di(2-ethylhexyl) phthalate in common marmosets: Lack of hepatic peroxisome proliferation, testicular atrophy or pancreatic acinar cell hyperplasia. Toxicol. Sci., 42, 49-56.
-
(1998)
Toxicol. Sci
, vol.42
, pp. 49-56
-
-
Kurata, Y.1
Kidachi, F.2
Yokoyama, M.3
Toyota, N.4
Tsuchitani, M.5
Katoh, M.6
-
17
-
-
84856877041
-
Metabolism of di (2-ethylhexyl) phthalate (DEHP): Comparative study in juvenile and fetal marmosets and rats
-
Kurata, Y., Makinodan, F., Shimamura, N. and Katoh, M. (2012): Metabolism of di (2-ethylhexyl) phthalate (DEHP): comparative study in juvenile and fetal marmosets and rats. J. Toxicol. Sci., 37, 33-49.
-
(2012)
J. Toxicol. Sci
, vol.37
, pp. 33-49
-
-
Kurata, Y.1
Makinodan, F.2
Shimamura, N.3
Katoh, M.4
-
18
-
-
60749089958
-
Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production
-
Lambrot, R., Muczynski, V., Lécureuil, C., Angenard, G., Coffigny, H., Pairault, C., Moison, D., Frydman, R., Habert, R. and Rouiller-Fabre, V. (2009): Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production. Environ. Health Perspect., 117, 32-37.
-
(2009)
Environ. Health Perspect
, vol.117
, pp. 32-37
-
-
Lambrot, R.1
Muczynski, V.2
Lécureuil, C.3
Angenard, G.4
Coffigny, H.5
Pairault, C.6
Moison, D.7
Frydman, R.8
Habert, R.9
Rouiller-Fabre, V.10
-
19
-
-
0032423198
-
Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats
-
Li, L.H., Jester, W.F. and Orth, J.M. (1998): Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats. Toxicol. Appl. Pharmacol., 153, 258-265.
-
(1998)
Toxicol. Appl. Pharmacol
, vol.153
, pp. 258-265
-
-
Li, L.H.1
Jester, W.F.2
Orth, J.M.3
-
20
-
-
0020334796
-
Toxic potential of the plasticizer Di(2-ethylhexyl) phthalate in the context of its disposition and metabolism in primates and man
-
Peck, C.C. and Albro, P.W. (1982): Toxic potential of the plasticizer Di(2-ethylhexyl) phthalate in the context of its disposition and metabolism in primates and man. Environ. Health Perspect., 45, 11-17.
-
(1982)
Environ. Health Perspect
, vol.45
, pp. 11-17
-
-
Peck, C.C.1
Albro, P.W.2
-
21
-
-
0030989774
-
Subchronic oral toxicity of di-N-octyl phthalate and di(2-ethylhexyl) phthalate in the rat
-
Poon, R., Lecavalier, P., Mueller, R., Valli, V.E., Procter, B.G. and Chu, I. (1997): Subchronic oral toxicity of di-N-octyl phthalate and di(2-ethylhexyl) phthalate in the rat. Food. Chem. Toxicol., 35, 225-239.
-
(1997)
Food. Chem. Toxicol
, vol.35
, pp. 225-239
-
-
Poon, R.1
Lecavalier, P.2
Mueller, R.3
Valli, V.E.4
Procter, B.G.5
Chu, I.6
-
22
-
-
0342733424
-
Effects of di-isononyl phthalate, di-2-ethylhexyl phthalate, and clofibrate in cynomolgus monkeys
-
Pugh, G.Jr., Isenberg, J.S., Kamendulis, L.M., Ackley, D.C., Clare, L.J., Brown, R., Lington, A.W., Smith, J.H. and Klaunig, J.E. (2000): Effects of di-isononyl phthalate, di-2-ethylhexyl phthalate, and clofibrate in cynomolgus monkeys. Toxicol. Sci., 56, 181-188.
-
(2000)
Toxicol. Sci
, vol.56
, pp. 181-188
-
-
Pugh Jr, G.1
Isenberg, J.S.2
Kamendulis, L.M.3
Ackley, D.C.4
Clare, L.J.5
Brown, R.6
Lington, A.W.7
Smith, J.H.8
Klaunig, J.E.9
-
23
-
-
0022560399
-
Comparative pharmacokinetics and subacute toxicity of di(2-ethylhexyl) phthalate (DEHP) in rats and marmosets: Extrapolation of effects in rodents to man
-
Rhodes, C., Orton, T.C., Pratt, I.S., Batten, P.L., Bratt, H., Jackson, S.J. and Elcombe, C.R. (1986): Comparative pharmacokinetics and subacute toxicity of di(2-ethylhexyl) phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man. Environ. Health. Perspect., 65, 299-307.
-
(1986)
Environ. Health. Perspect
, vol.65
, pp. 299-307
-
-
Rhodes, C.1
Orton, T.C.2
Pratt, I.S.3
Batten, P.L.4
Bratt, H.5
Jackson, S.J.6
Elcombe, C.R.7
-
24
-
-
0021823729
-
Excretion and metabolism of di(2-ethylhexyl)phthalate in man
-
Schmid, P. and Schlatter, C. (1985). Excretion and metabolism of di(2-ethylhexyl)phthalate in man. Xenobiotica, 15, 251-256.
-
(1985)
Xenobiotica
, vol.15
, pp. 251-256
-
-
Schmid, P.1
Schlatter, C.2
-
25
-
-
0034112732
-
Effect of neonatal gonadotropin-releasing hormone antagonist admistration on sertoli cell number and testicular development in the marmoset: Comparison with the rat
-
Sharpe, R.M., Walker, M., Millar, M.R., Atanassova, N., Morris, K., McKinnell, C., Saunders, P.T.K. and Fraser, H.M. (2000): Effect of neonatal gonadotropin-releasing hormone antagonist admistration on sertoli cell number and testicular development in the marmoset: Comparison with the rat. Biol. Reprod., 62, 1685-1693.
-
(2000)
Biol. Reprod
, vol.62
, pp. 1685-1693
-
-
Sharpe, R.M.1
Walker, M.2
Millar, M.R.3
Atanassova, N.4
Morris, K.5
McKinnell, C.6
Saunders, P.T.K.7
Fraser, H.M.8
-
26
-
-
0023629398
-
Metabolic and peroxisome proliferation studies with di(2-ethylhexyl) phthalate in rats and monkeys
-
Short, R.D., Robinson, E.C., Lington, A.W. and Chin, A.E. (1987). Metabolic and peroxisome proliferation studies with di(2-ethylhexyl) phthalate in rats and monkeys. Toxicol. Ind. Health., 3, 185-194.
-
(1987)
Toxicol. Ind. Health
, vol.3
, pp. 185-194
-
-
Short, R.D.1
Robinson, E.C.2
Lington, A.W.3
Chin, A.E.4
-
27
-
-
0022500653
-
Effects of di-(2-ethylhexyl)phthalate and five of its metabolites on rat testis in vivo and in vitro
-
Sjöerg, P., Bondesson, U., Gray, T.J. and Plön, L. (1986): Effects of di-(2-ethylhexyl)phthalate and five of its metabolites on rat testis in vivo and in vitro. Acta. Pharmacol. Toxicol., 58, 225-233.
-
(1986)
Acta. Pharmacol. Toxicol
, vol.58
, pp. 225-233
-
-
Sjöerg, P.1
Bondesson, U.2
Gray, T.J.3
Plön, L.4
-
28
-
-
12444333169
-
Evaluation of antiandrogenic activity of di-(2-ethylhexyl)phthalate
-
Stroheker, T., Cabaton, N., Nourdin, G., Régnier, J.F., Lhuguenot, J.C. and Chagnon, M.C. (2005): Evaluation of antiandrogenic activity of di-(2-ethylhexyl)phthalate. Toxicology, 208, 115-121.
-
(2005)
Toxicology
, vol.208
, pp. 115-121
-
-
Stroheker, T.1
Cabaton, N.2
Nourdin, G.3
Régnier, J.F.4
Lhuguenot, J.C.5
Chagnon, M.C.6
-
29
-
-
33746448400
-
Effect of di(2-ethylhexyl) phthalate (DEHP) on genital organs from juvenile common marmosets: I. Morphological and biochemical investigation in 65-week toxicity study
-
Tomonari, Y., Kurata, Y., David, R.M., Gans, G., Kawasuso, T. and Katoh, M. (2006): Effect of di(2-ethylhexyl) phthalate (DEHP) on genital organs from juvenile common marmosets: I. Morphological and biochemical investigation in 65-week toxicity study. J. Toxicol. Environ. Health A., 69, 1651-1672.
-
(2006)
J. Toxicol. Environ. Health A
, vol.69
, pp. 1651-1672
-
-
Tomonari, Y.1
Kurata, Y.2
David, R.M.3
Gans, G.4
Kawasuso, T.5
Katoh, M.6
-
30
-
-
0003871544
-
-
WHO, Ethical Principles for Medical Research Involving Human Subjects
-
WHO (2000): World Medical Association Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects.
-
(2000)
World Medical Association Declaration of Helsinki
-
-
|