Cholinergic degeneration and alterations in the TrkA and p75NTR balance as a result of pro-NGF injection into aged rats

Journal of Aging Research

Volumn 2011, Issue , 2011, Pages

  Fortress, Ashley M ^a   Buhusi, Mona ^a   Helke, Kris L ^a   Granholm, Ann Charlotte E ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; NEUROTROPHIN RECEPTOR P75; PRONERVE GROWTH FACTOR; PROTEIN PRECURSOR; PROTEIN TYROSINE KINASE A; UNCLASSIFIED DRUG;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; FOREBRAIN; HIPPOCAMPUS; IN VIVO STUDY; MALE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 84859269517     PISSN: 20902204     EISSN: 20902212     Source Type: Journal    
DOI: 10.4061/2011/460543     Document Type: Article

References (34)

1. Bierer L. M., Haroutunian V., Gabriel S., Knott P. J., Carlin L. S., Purohit D. P., Perl D. P., Schmeidler J., Kanof P., Davis K. L., Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits. Journal of Neurochemistry 1995 64 2 749 760 2-s2.0-0028873975
2. Schneider L. S., lschneid@usc.edu Insel P. S., Weiner M. W., Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's disease neuroimaging initiative. Archives of Neurology 2011 68 1 58 66 10.1001/archneurol.2010.343
3. Fahnestock M., Michalski B., Xu B., Coughlin M. D., The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Molecular and Cellular Neuroscience 2001 18 2 210 220 2-s2.0-0034848604 10.1006/mcne.2001.1016 (Pubitemid 32846529)
4. Al-Shawi R., Hafner A., Olson J., Chun S., Raza S., Thrasivoulou C., Lovestone S., Killick R., Simons P., Cowen T., Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system. European Journal of Neuroscience 2008 27 8 2103 2114 2-s2.0-42049088076 10.1111/j.1460-9568.2008.06152.x (Pubitemid 351521477)
5. Peng S., Wuu J., Mufson E. J., Fahnestock M., Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. Journal of Neuropathology and Experimental Neurology 2004 63 6 641 649 2-s2.0-2942536284 (Pubitemid 38736427)
6. Volosin M., Trotter C., Cragnolini A., Kenchappa R. S., Light M., Hempstead B. L., Carter B. D., Friedman W. J., Induction of proneurotrophins and activation of p75-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. Journal of Neuroscience 2008 28 39 9870 9879 2-s2.0-55749104402 10.1523/JNEUROSCI.2841-08.2008
7. Jurič D. M., Čarman-Kržan M., Interleukin-1 β but not IL-1 α mediates nerve growth factor secretion from rat astrocytes via type I IL-1 receptor. International Journal of Developmental Neuroscience 2001 19 7 675 683 2-s2.0-0034765960 10.1016/S0736-5748(01)00044-2 (Pubitemid 33035036)
8. Friedman W. J., Proneurotrophins, seizures, and neuronal apoptosis. Neuroscientist 2010 16 3 244 252 2-s2.0-77952644392 10.1177/1073858409349903
9. Volosin M., Song W., Almeida R. D., Kaplan D. R., Hempstead B. L., Friedman W. J., Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. Journal of Neuroscience 2006 26 29 7756 7766 2-s2.0-33747051514 10.1523/JNEUROSCI.1560-06.2006 (Pubitemid 44315195)
10. Bruno M. A., Leon W. C., Fragoso G., Mushynski W. E., Almazan G., Cuello A. C., Amyloid β -induced nerve growth factor dysmetabolism in Alzheimer disease. Journal of Neuropathology and Experimental Neurology 2009 68 8 857 869 2-s2.0-69449097269 10.1097/NEN.0b013e3181aed9e6
11. Pedraza C. E., Podlesniy P., Vidal N., Arévalo J. C., Lee R., Hempstead B., Ferrer I., Iglesias M., Espinet C., Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR. American Journal of Pathology 2005 166 2 533 543 2-s2.0-13244288122 (Pubitemid 40189049)
12. Cooper J. D., Salehi A., Delcroix J. D., Howe C. L., Belichenko P. V., Chua-Couzens J., Kilbridge J. F., Carlson E. J., Epstein C. J., Mobley W. C., Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proceedings of the National Academy of Sciences of the United States of America 2001 98 18 10439 10444 2-s2.0-2942591228 10.1073/pnas.181219298 (Pubitemid 32803038)
13. Kelly A., Maguire C., Lynch M. A., Deficits in nerve growth factor release and tyrosine receptor kinase phosphorylation are associated with age-related impairment in long-term potentiation in the dentate gyrus. Neuroscience 1999 95 2 359 365 2-s2.0-0032714367 10.1016/S0306-4522(99)00460-1
14. Hunter C. L., Bimonte H. A., Granholm A. C. E., Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory. Behavioural Brain Research 2003 138 2 121 131 2-s2.0-0037460101 10.1016/S0166-4328(02)00275-9 (Pubitemid 36071351)
15. Salehi A., Delcroix J. D., Swaab D. F., Alzheimer's disease and NGF signaling. Journal of Neural Transmission 2004 111 3 323 345 2-s2.0-1542283606 10.1007/s00702-003-0091-x (Pubitemid 38316609)
16. Williams B. J., Eriksdotter-Jonhagen M., Granholm A. C., Nerve growth factor in treatment and pathogenesis of Alzheimer's disease. Progress in Neurobiology 2006 80 3 114 128 2-s2.0-33750963813 10.1016/j.pneurobio.2006.09. 001 (Pubitemid 44739167)
17. Williams B., Granholm A. C., Sambamurti K., Age-dependent loss of NGF signaling in the rat basal forebrain is due to disrupted MAPK activation. Neuroscience Letters 2007 413 2 110 114 2-s2.0-33846574233 10.1016/j.neulet. 2006.11.040 (Pubitemid 46177399)
18. Ledesma M. D., Abad-Rodriguez J., Galvan C., Biondi E., Navarro P., Delacourte A., Dingwall C., Dotti C. G., Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains. EMBO Reports 2003 4 12 1190 1196 2-s2.0-0346463111 10.1038/sj.embor.7400021 (Pubitemid 38088415)
19. Melchor J. P., Pawlak R., Strickland S., The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid- β (A β) degradation and inhibits A β -induced neurodegeneration. Journal of Neuroscience 2003 23 26 8867 8871 2-s2.0-0141641077 (Pubitemid 37210899)
20. Liu R. M., van Groen T., Katre A., Cao D., Kadisha I., Ballinger C., Wang L., Carroll S. L., Li L., Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease. Neurobiology of Aging 2011 32 6 1079 1089 2-s2.0-67650034635 10.1016/j.neurobiolaging.2009.06.003
21. Sobottka B., Reinhardt D., Brockhaus M., Jacobsen H., Metzger F., ProNGF inhibits NGF-mediated TrkA activation in PC12 cells. Journal of Neurochemistry 2008 107 5 1294 1303
22. Song W., Volosin M., Cragnolini A. B., Hempstead B. L., Friedman W. J., wilmaf@andromeda.rutgers.edu ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons. Journal of Neuroscience 2010 30 46 15608 15615 10.1523/JNEUROSCI.2581-10.2010
23. Williams B., Nelson M., Granholm A. C., Coultrap S., Browning M., Curtis M., Altered NGF response but not release in the aged septo-hippocampal cholinergic system. Experimental Neurology 2005 196 1 30 40 (Pubitemid 41417783)
24. Jullien J., Guili V., Reichardt L. F., Rudkin B. B., Molecular kinetics of nerve growth factor receptor trafficking and activation. Journal of Biological Chemistry 2002 277 41 38700 38708 2-s2.0-0037064037 10.1074/jbc.M202348200 (Pubitemid 35154731)
25. Deppmann C. D., Mihalas S., Sharma N., Lonze B. E., Niebur E., Ginty D. D., A model for neuronal competition during development. Science 2008 320 5874 369 373 2-s2.0-42349090693 10.1126/science.1152677 (Pubitemid 351555658)
26. Bai Y., Dergham P., Nedev H., Xu J., Galan A., Rivera J. C., ZhiHua S., Mehta H. M., Woo S. B., Sarunic M. V., Neet K. E., Saragovi H. U., uri.saragovi@mcgill.ca Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism. Journal of Biological Chemistry 2010 285 50 39392 39400 10.1074/jbc.M110.147801
27. Mufson E. J., Lavine N., Jaffar S., Kordower J. H., Quirion R., Saragovi H. U., Reduction in p140-trkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease. Experimental Neurology 1997 146 1 91 103 2-s2.0-0031194454 10.1006/exnr.1997.6504 (Pubitemid 27319723)
28. Roskoden T., Otten U., Schwegler H., Early postnatal corticosterone administration regulates neurotrophins and their receptors in septum and hippocampus of the rat. Experimental Brain Research 2004 154 2 183 191 2-s2.0-1642538217 10.1007/s00221-003-1656-5 (Pubitemid 38134623)
29. Fiore M., Amendola T., Triaca V., Alleva E., Aloe L., Fighting in the aged male mouse increases the expression of TrkA and TrkB in the subventricular zone and in the hippocampus. Behavioural Brain Research 2005 157 2 351 362 2-s2.0-11444262461 10.1016/j.bbr.2004.08.024 (Pubitemid 40082578)
30. Bulbarelli A., Lonati E., Cazzaniga E., Re F., Sesana S., Barisani D., Sancini G., Mutoh T., Masserini M., TrkA pathway activation induced by amyloid-beta (Abeta). Molecular and Cellular Neuroscience 2009 40 3 365 373 2-s2.0-60149109230 10.1016/j.mcn.2008.12.006
31. Bäckman C., Rose G. M., Hoffer B. J., Henry M. A., Bartus R. T., Friden P., Granholm A. C., Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy. Journal of Neuroscience 1996 16 17 5437 5442 2-s2.0-0029843679 (Pubitemid 26277872)
32. Nykjaer A., Lee R., Teng K. K., Jansen P., Madsen P., Nielsen M. S., Jacobsen C., Kliemannel M., Schwarz E., Willnow T. E., Hempstead B. L., Petersen C. M., Sortilin is essential for proNGF-induced neuronal cell death. Nature 2004 427 6977 843 848 2-s2.0-10744219632 10.1038/nature02319 (Pubitemid 38297746)
33. Terry A. V. Jr., Kutiyanawalla A., Pillai A., Age-dependent alterations in nerve growth factor (NGF)-related proteins, sortilin, and learning and memory in rats. Physiology & Behavior 2011 102 2 149 157
34. Vaegter C. B., cv@biokemi.au.dk Jansen P., Fjorback A. W., Glerup S., Skeldal S., Kjolby M., Richner M., Erdmann B., Nyengaard J. R., Tessarollo L., Lewin G. R., Willnow T. E., Chao M. V., Nykjaer A., an@biokemi.au.dk Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nature Neuroscience 2011 14 1 54 63 10.1038/nn.2689